KIAA1328 Gene
protein-coding GIFtS: 40
GCID: GC18P034483
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KIAA1328
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Aliases
for KIAA1328 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KIAA13281 2 | | Hinderin1 | | Uncharacterized Protein KIAA13282 |
Export aliases for KIAA1328 gene to outside databasesPrevious GC identifers: GC18P034232 GC18P032661 GC18P032663 GC18P031267 |
Summaries
for KIAA1328 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KIAA1328 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010966.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA1328 gene promoter:
HSF1 (long) Nkx5-1 Pax-3 PPAR-gamma1 CBF-A CBF-B HSF1short PPAR-gamma2 Pax-4a CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA1328
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1328 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18q12.2 Ensembl cytogenetic band: 18q12.2 HGNC cytogenetic band: 18q12.2KIAA1328 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18P034483: view genomic region
(about GC identifiers)
Start:
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34,409,069 bp from pter |
End:
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34,811,481 bp from pter |
Size:
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402,413 bases |
Orientation:
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plus strand |
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Proteins
for KIAA1328 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: K1328_HUMAN, Q86T90 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA1328 Size: 577 amino acids; 65373 Da
Sequence caution: Sequence=BAA92566.2; Type=Erroneous initiation;
Secondary accessions: Q05DL0 Q49AG6 Q9P2L8Alternative splicing: 4 isoforms: Q86T90-1 Q86T90-2 Q86T90-3 Q86T90-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KIAA1328: NX_Q86T90
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86T90
KIAA1328 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065827.1
ENSEMBL proteins: ENSP00000468653 ENSP00000280020 ENSP00000465036 ENSP00000467248 ENSP00000466355 ENSP00000465550 ENSP00000467507 ENSP00000441359 ENSP00000390515
Human Recombinant Protein Products:
KIAA1328 Antibody Products:
Assay Products for KIAA1328: |
Protein
Domains /
Families
for KIAA1328 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q86T90 |
Function
for KIAA1328 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1328 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1328
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: KIAA1328 (NM_020776) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1328 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1328 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1328 |
1 GenomeRNAi human phenotype for KIAA1328:
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Pathways & Interactions
for KIAA1328 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1328
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for KIAA1328 (Q86T903 ENSP000002800204) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for KIAA1328 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA1328
Search CenterWatch for drugs/clinical trials and news about KIAA1328 / K1328
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Transcripts
for KIAA1328 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIAA1328 gene: NM_020776.1 Unigene Cluster for KIAA1328: KIAA1328 Hs.4045 [show with all ESTs]Unigene Representative Sequence: AB03774912 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592611 ENST00000280020(uc002kzz.3 uc002lab.3 uc002lac.1)
ENST00000592521 ENST00000590617 ENST00000587139 ENST00000591619 ENST00000591911
ENST00000590456 ENST00000586135 ENST00000586501 ENST00000543923 ENST00000435985(uc021uiw.1 uc002lad.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1328 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1328
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIAA1328 (NM_020776) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1328 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1328 |
Additional cDNA sequence: AB037749.2 AK292288.1 AK304230.1 AL832625.2 BC008670.1 BC037903.1 BC045585.1 BC127204.1 BX648875.1 10 DOTS entries: DT.99954251 DT.212377 DT.95359245 DT.40106499 DT.95113083 DT.95316013 DT.95359246 DT.100651785 DT.91841765 DT.121104318 24/40 AceView cDNA sequences (see all 40): AW466880 BC008670 BF058927 AA774587 BU608573 AB037749 BI860191 BQ181150 AA456093 BC045585 BC037903 BM799992 D59640 D59747 AI015609 AK130479 BI459488 BX648875 AL832625 AW084689 BM927293 D59639 AA889675 BE784176
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1328 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b |
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| SP1: | | | | | | | | | - | | - | | | | | | - | | | | | | - | | | | | | |
| SP2: | | | | | - | | | | - | | - | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KIAA1328
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Expression
for KIAA1328 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA1328 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAACATTTT
About this image
See KIAA1328 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA1328
SOURCE GeneReport for Unigene cluster: Hs.4045
SABiosciences Custom PCR Arrays for KIAA1328
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1328
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat KIAA1328 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1328 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1328 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1328 |
Orthologs
for KIAA1328 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KIAA1328 gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for KIAA1328 (if available)
TreeFam Gene Tree for KIAA1328 (if available) |
Paralogs
for KIAA1328 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIAA1328 gene
KIAA1328 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for KIAA1328
PGOHUM00000237824
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Genomic Variants
for KIAA1328 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIAA1328 (34409069 - 34659069 bp, first 250kb of KIAA1328)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for KIAA1328
9 CNVs: 77846 4056 88787 67330 8857 88788 9779 1972 3165
1 Indel: 77847 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1328 |
|
Disorders
/ Diseases
for KIAA1328 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for KIAA1328 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA1328 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with KIAA1328) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (2000)
- A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- Hinderin, a five-domains protein including coiled-coil motifs that binds to SMC3. (PubMed id 15656913)1 Patel C.A. and Ghiselli G. (2005)
- DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for KIAA1328 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA1328 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIAA1328 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA1328 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA1328 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KIAA1328 gene:
Search GeneIP for patents involving KIAA1328
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA1328 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1328 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1328 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1328 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA1328 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1328 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1328 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1328 |
|  |  |  | | | | Search ThermoFisher Antibodies for KIAA1328 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1328 |
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