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Aliases for KIAA1211L Gene

Aliases for KIAA1211L Gene

  • KIAA1211 Like 2 3 5
  • C2orf55 3 4
  • Uncharacterized Protein KIAA1211-Like 3
  • Chromosome 2 Open Reading Frame 55 2
  • Uncharacterized Protein C2orf55 3

External Ids for KIAA1211L Gene

Previous HGNC Symbols for KIAA1211L Gene

  • C2orf55

Previous GeneCards Identifiers for KIAA1211L Gene

  • GC02M099411

Summaries for KIAA1211L Gene

GeneCards Summary for KIAA1211L Gene

KIAA1211L (KIAA1211 Like) is a Protein Coding gene. An important paralog of this gene is KIAA1211.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1211L Gene

Genomics for KIAA1211L Gene

Regulatory Elements for KIAA1211L Gene

Enhancers for KIAA1211L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F098908 1 FANTOM5 Ensembl ENCODE 17.1 +25.1 25059 6.0 PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF48 FOS ZNF202 LOC550644 ENSG00000273306 UNC50 REV1 MITD1 KIAA1211L COA5 TSGA10 RNU7-46P
GH02F098708 1.1 Ensembl ENCODE 14.6 +225.6 225559 3.8 RAD21 ZKSCAN1 YY1 KIAA1211L MGAT4A RNU4-84P INPP4A YWHAQP5
GH02F099023 1 FANTOM5 10.4 -86.9 -86930 0.2 TSGA10 KIAA1211L LOC550644
GH02F099040 0.5 Ensembl 10.2 -104.6 -104643 0.2 JUND IRF1 SETDB1 KIAA1211L LOC550644
GH02F098691 0.6 FANTOM5 9.9 +244.8 244760 0.2 SOX13 SOX5 RFX1 JUN FOS MGAT4A KIAA1211L INPP4A LIPT1 TSGA10 YWHAQP5 PIR38295
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around KIAA1211L on UCSC Golden Path with GeneCards custom track

Promoters for KIAA1211L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000595108 58 1600 CTCF SUZ12 CBX2 FEZF1 HIC1 ZFHX2 ZNF524 ZBTB26 PRDM1 ZBTB20

Genomic Location for KIAA1211L Gene

Chromosome:
2
Start:
98,793,846 bp from pter
End:
98,936,259 bp from pter
Size:
142,414 bases
Orientation:
Minus strand

Genomic View for KIAA1211L Gene

Genes around KIAA1211L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1211L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1211L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1211L Gene

Proteins for KIAA1211L Gene

  • Protein details for KIAA1211L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NV74-K121L_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1211-like
    Protein Accession:
    Q6NV74

    Protein attributes for KIAA1211L Gene

    Size:
    962 amino acids
    Molecular mass:
    102157 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH68277.1; Type=Frameshift; Positions=503, 725; Evidence={ECO:0000305};

neXtProt entry for KIAA1211L Gene

Post-translational modifications for KIAA1211L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KIAA1211L Gene

Domains & Families for KIAA1211L Gene

Protein Domains for KIAA1211L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1211L: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1211L Gene

Function for KIAA1211L Gene

genes like me logo Genes that share phenotypes with KIAA1211L: view

Animal Models for KIAA1211L Gene

MGI Knock Outs for KIAA1211L:

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for KIAA1211L Gene

Localization for KIAA1211L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1211L Gene COMPARTMENTS Subcellular localization image for KIAA1211L gene
Compartment Confidence
nucleus 3
cytoskeleton 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1211L Gene

Pathways & Interactions for KIAA1211L Gene

SuperPathways for KIAA1211L Gene

No Data Available

Interacting Proteins for KIAA1211L Gene

Selected Interacting proteins: Q6NV74-K121L_HUMAN for KIAA1211L Gene via IID

Symbol External ID(s) Details
NRAP
YWHAE

Gene Ontology (GO) - Biological Process for KIAA1211L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1211L Gene

Transcripts for KIAA1211L Gene

Unigene Clusters for KIAA1211L Gene

KIAA1211-like:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1211L Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: - - -
SP2: - -
SP3:
SP4: - - - -
SP5:

Relevant External Links for KIAA1211L Gene

GeneLoc Exon Structure for
KIAA1211L
ECgene alternative splicing isoforms for
KIAA1211L

Expression for KIAA1211L Gene

mRNA expression in normal human tissues for KIAA1211L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA1211L Gene

This gene is overexpressed in Brain - Cortex (x5.9), Brain - Frontal Cortex (BA9) (x5.2), and Brain - Nucleus accumbens (basal ganglia) (x4.3).

Protein differential expression in normal tissues from HIPED for KIAA1211L Gene

This gene is overexpressed in Frontal cortex (33.4) and Brain (30.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA1211L Gene



Protein tissue co-expression partners for KIAA1211L Gene

NURSA nuclear receptor signaling pathways regulating expression of KIAA1211L Gene:

KIAA1211L

SOURCE GeneReport for Unigene cluster for KIAA1211L Gene:

Hs.469398
genes like me logo Genes that share expression patterns with KIAA1211L: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for KIAA1211L Gene

Orthologs for KIAA1211L Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1211L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1211L 34 35
  • 99.13 (n)
cow
(Bos Taurus)
Mammalia KIAA1211L 34
  • 77.28 (n)
dog
(Canis familiaris)
Mammalia C10H2orf55 34
  • 76.94 (n)
KIAA1211L 35
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1310819 34
  • 73.49 (n)
mouse
(Mus musculus)
Mammalia 2010300C02Rik 34 16 35
  • 71.82 (n)
oppossum
(Monodelphis domestica)
Mammalia KIAA1211L 35
  • 45 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 20 (a)
ManyToMany
chicken
(Gallus gallus)
Aves KIAA1211L 35
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 59 (a)
OneToMany
-- 35
  • 21 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii si:ch211-149l1.2 35
  • 25 (a)
OneToMany
si:ch211-121j5.4 35
  • 17 (a)
OneToMany
Species where no ortholog for KIAA1211L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1211L Gene

ENSEMBL:
Gene Tree for KIAA1211L (if available)
TreeFam:
Gene Tree for KIAA1211L (if available)

Paralogs for KIAA1211L Gene

Paralogs for KIAA1211L Gene

genes like me logo Genes that share paralogs with KIAA1211L: view

Variants for KIAA1211L Gene

Sequence variations from dbSNP and Humsavar for KIAA1211L Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10169003 -- 98,892,403(+) aGATC(C/T)GAGCA intron-variant
rs10169573 -- 98,930,246(+) GCAGA(C/G)CAAGA intron-variant
rs10172158 -- 98,893,142(+) GCTCC(C/T)TGCAC intron-variant
rs10175560 -- 98,848,955(+) GTCTA(C/T)ACTCA intron-variant
rs10178956 -- 98,895,311(+) ACAGT(G/T)GGGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1211L Gene

Variant ID Type Subtype PubMed ID
esv1435269 CNV insertion 17803354
esv2277586 CNV deletion 18987734
esv3591730 CNV loss 21293372
nsv1071606 CNV deletion 25765185
nsv1114119 CNV deletion 24896259
nsv1133478 CNV deletion 24896259
nsv2842 CNV insertion 18451855
nsv582517 CNV loss 21841781
nsv582518 CNV loss 21841781
nsv834310 CNV gain+loss 17160897

Variation tolerance for KIAA1211L Gene

Residual Variation Intolerance Score: 28.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.95; 68.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA1211L Gene

Human Gene Mutation Database (HGMD)
KIAA1211L
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1211L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1211L Gene

Disorders for KIAA1211L Gene

Relevant External Links for KIAA1211L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA1211L

No disorders were found for KIAA1211L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1211L Gene

Publications for KIAA1211L Gene

  1. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 64
  3. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. (PMID: 19416921) Scott L.J. … Boehnke M. (Proc. Natl. Acad. Sci. U.S.A. 2009) 3 64
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for KIAA1211L Gene

Sources for KIAA1211L Gene

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