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Aliases for KIAA1211 Gene

Aliases for KIAA1211 Gene

  • KIAA1211 2 3

External Ids for KIAA1211 Gene

Previous GeneCards Identifiers for KIAA1211 Gene

  • GC04P056984
  • GC04P057142
  • GC04P057025
  • GC04P057090
  • GC04P056951
  • GC04P056877
  • GC04U900691
  • GC04P056731
  • GC04P057036
  • GC04P052990
  • GC04P056170

Summaries for KIAA1211 Gene

GeneCards Summary for KIAA1211 Gene

KIAA1211 (KIAA1211) is a Protein Coding gene. An important paralog of this gene is KIAA1211L.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1211 Gene

Genomics for KIAA1211 Gene

Regulatory Elements for KIAA1211 Gene

Enhancers for KIAA1211 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around KIAA1211 on UCSC Golden Path with GeneCards custom track

Promoters for KIAA1211 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for KIAA1211 Gene

Chromosome:
4
Start:
56,049,073 bp from pter
End:
56,330,724 bp from pter
Size:
281,652 bases
Orientation:
Plus strand

Genomic View for KIAA1211 Gene

Genes around KIAA1211 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1211 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1211 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1211 Gene

Proteins for KIAA1211 Gene

  • Protein details for KIAA1211 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZU35-K1211_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1211
    Protein Accession:
    Q6ZU35
    Secondary Accessions:
    • Q9NTE2
    • Q9NTP8
    • Q9ULK9

    Protein attributes for KIAA1211 Gene

    Size:
    1233 amino acids
    Molecular mass:
    136760 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA86525.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305}; Sequence=CAB61360.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for KIAA1211 Gene

Post-translational modifications for KIAA1211 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1211 Gene

No data available for DME Specific Peptides for KIAA1211 Gene

Domains & Families for KIAA1211 Gene

Protein Domains for KIAA1211 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA1211 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1211: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KIAA1211 Gene

Function for KIAA1211 Gene

Phenotypes for KIAA1211 Gene

GenomeRNAi human phenotypes for KIAA1211:
genes like me logo Genes that share phenotypes with KIAA1211: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1211 Gene

Localization for KIAA1211 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1211 Gene COMPARTMENTS Subcellular localization image for KIAA1211 gene
Compartment Confidence
nucleus 4
golgi apparatus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1211 Gene

Pathways & Interactions for KIAA1211 Gene

SuperPathways for KIAA1211 Gene

No Data Available

Interacting Proteins for KIAA1211 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000264229%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000264229 Q6ZU35-K1211_HUMAN for KIAA1211 Gene via STRING IID

Gene Ontology (GO) - Biological Process for KIAA1211 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1211 Gene

Drugs & Compounds for KIAA1211 Gene

No Compound Related Data Available

Transcripts for KIAA1211 Gene

Unigene Clusters for KIAA1211 Gene

KIAA1211:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1211 Gene

No ASD Table

Relevant External Links for KIAA1211 Gene

GeneLoc Exon Structure for
KIAA1211
ECgene alternative splicing isoforms for
KIAA1211

Expression for KIAA1211 Gene

mRNA expression in normal human tissues for KIAA1211 Gene

mRNA differential expression in normal tissues according to GTEx for KIAA1211 Gene

This gene is overexpressed in Testis (x13.7).

Protein differential expression in normal tissues from HIPED for KIAA1211 Gene

This gene is overexpressed in Gallbladder (23.5), Peripheral blood mononuclear cells (17.5), and Fetal Brain (11.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KIAA1211 Gene



NURSA nuclear receptor signaling pathways regulating expression of KIAA1211 Gene:

KIAA1211

SOURCE GeneReport for Unigene cluster for KIAA1211 Gene:

Hs.596667
genes like me logo Genes that share expression patterns with KIAA1211: view

Primer Products

No data available for Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for KIAA1211 Gene

Orthologs for KIAA1211 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1211 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia KIAA1211 34
  • 79.43 (n)
  • 75.53 (a)
MGC148692 35
  • 67 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia KIAA1211 34
  • 99.41 (n)
  • 99.03 (a)
KIAA1211 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1211 35
  • 63 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1211 35
  • 49 (a)
OneToOne
mouse
(Mus musculus)
Mammalia C530008M17Rik 35
  • 61 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1211 35
  • 31 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA1211 35
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1211 35
  • 72 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:dkeyp-117h8.2 35
  • 39 (a)
OneToOne
Species where no ortholog for KIAA1211 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1211 Gene

ENSEMBL:
Gene Tree for KIAA1211 (if available)
TreeFam:
Gene Tree for KIAA1211 (if available)

Paralogs for KIAA1211 Gene

Paralogs for KIAA1211 Gene

genes like me logo Genes that share paralogs with KIAA1211: view

Variants for KIAA1211 Gene

Sequence variations from dbSNP and Humsavar for KIAA1211 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs6823339 - 56,314,307(+) AGGAG(A/C)TCTTG reference, missense
rs7672073 - 56,315,466(+) GCCCC(A/C/G)CCAGG reference, missense
rs3796546 - 56,315,631(+) CCAAC(A/G)GAAGA reference, missense
rs3796547 - 56,315,829(+) GAAGT(C/T)GGAGA reference, missense
rs4142 -- 56,102,891(+) TGCTC(A/C/T)GCTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1211 Gene

Variant ID Type Subtype PubMed ID
dgv5212n100 CNV loss 25217958
dgv5213n100 CNV gain 25217958
esv2671346 CNV deletion 23128226
esv3569433 CNV loss 25503493
esv3600570 CNV loss 21293372
esv3600571 CNV gain 21293372
nsv1012036 CNV gain 25217958
nsv1161086 CNV duplication 26073780
nsv293732 CNV deletion 16902084
nsv518368 CNV loss 19592680
nsv818233 CNV gain 17921354
nsv829940 CNV gain 17160897

Variation tolerance for KIAA1211 Gene

Residual Variation Intolerance Score: 66.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.62; 98.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA1211 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1211

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1211 Gene

Disorders for KIAA1211 Gene

Relevant External Links for KIAA1211

Genetic Association Database (GAD)
KIAA1211
Human Genome Epidemiology (HuGE) Navigator
KIAA1211
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA1211

No disorders were found for KIAA1211 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1211 Gene

Publications for KIAA1211 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 65
  2. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  4. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 65
  5. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 65

Products for KIAA1211 Gene

Sources for KIAA1211 Gene

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