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Aliases for KIAA1211 Gene

Aliases for KIAA1211 Gene

  • KIAA1211 2 3

External Ids for KIAA1211 Gene

Previous GeneCards Identifiers for KIAA1211 Gene

  • GC04P056984
  • GC04P057142
  • GC04P057025
  • GC04P057090
  • GC04P056951
  • GC04P056877
  • GC04U900691
  • GC04P056731
  • GC04P057036
  • GC04P052990
  • GC04P056170

Summaries for KIAA1211 Gene

GeneCards Summary for KIAA1211 Gene

KIAA1211 (KIAA1211) is a Protein Coding gene. An important paralog of this gene is KIAA1211L.

Additional gene information for KIAA1211 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1211 Gene

Genomics for KIAA1211 Gene

GeneHancer (GH) Regulatory Elements for KIAA1211 Gene

Promoters and enhancers for KIAA1211 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I056048 Promoter/Enhancer 1.4 Ensembl ENCODE 564.6 +0.5 510 2.4 ARNT SIN3A GLIS2 ZNF302 ZNF143 ATF7 YY2 REST SMARCA4 GLIS1 KIAA1211 ENSG00000269921 ENSG00000270147 ENSG00000272969 CLOCK GC04P056007 RNA5SP161
GH04I056224 Promoter 0.6 EPDnew 550.1 +175.9 175922 0.1 NFIB KIAA1211 LOC101928760 RNA5SP161
GH04I056053 Enhancer 1 VISTA ENCODE 14.8 +6.5 6452 4.2 FOXA2 FOXA3 MNT POLR2A CEBPA PRDM10 HOMEZ MIXL1 KIAA1211 SRD5A3-AS1 RNA5SP161 GC04P056007
GH04I056300 Enhancer 1.2 Ensembl ENCODE dbSUPER 5.3 +252.4 252379 1.5 CTCF SAP130 ARID4B MAX BACH1 BMI1 ZNF48 RAD21 TEAD3 ZNF335 AASDH KIAA1211 GC04M056306 RNU6-197P
GH04I056234 Enhancer 0.4 dbSUPER 11 +186.6 186608 2.9 MEIS2 RCOR1 KIAA1211 RNU6-197P LOC101928760 RNA5SP161
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around KIAA1211 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KIAA1211 gene promoter:

Genomic Locations for KIAA1211 Gene

Genomic Locations for KIAA1211 Gene
chr4:56,049,073-56,330,724
(GRCh38/hg38)
Size:
281,652 bases
Orientation:
Plus strand
chr4:57,036,361-57,196,890
(GRCh37/hg19)

Genomic View for KIAA1211 Gene

Genes around KIAA1211 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1211 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1211 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1211 Gene

Proteins for KIAA1211 Gene

  • Protein details for KIAA1211 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZU35-K1211_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1211
    Protein Accession:
    Q6ZU35
    Secondary Accessions:
    • Q9NTE2
    • Q9NTP8
    • Q9ULK9

    Protein attributes for KIAA1211 Gene

    Size:
    1233 amino acids
    Molecular mass:
    136760 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA86525.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305}; Sequence=CAB61360.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for KIAA1211 Gene

Post-translational modifications for KIAA1211 Gene

No Post-translational modifications

No data available for DME Specific Peptides for KIAA1211 Gene

Domains & Families for KIAA1211 Gene

Gene Families for KIAA1211 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA1211 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA1211 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1211: view

No data available for UniProtKB/Swiss-Prot for KIAA1211 Gene

Function for KIAA1211 Gene

Phenotypes From GWAS Catalog for KIAA1211 Gene

Phenotypes for KIAA1211 Gene

GenomeRNAi human phenotypes for KIAA1211:
genes like me logo Genes that share phenotypes with KIAA1211: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1211 Gene

Localization for KIAA1211 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA1211 gene
Compartment Confidence
nucleus 4
golgi apparatus 2
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1211 Gene

Pathways & Interactions for KIAA1211 Gene

SuperPathways for KIAA1211 Gene

No Data Available

Interacting Proteins for KIAA1211 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000264229%0d%0a9606.ENSP00000354947%0d%0a
Selected Interacting proteins: Q6ZU35-K1211_HUMAN ENSP00000264229 for KIAA1211 Gene via IID STRING

Gene Ontology (GO) - Biological Process for KIAA1211 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1211 Gene

Drugs & Compounds for KIAA1211 Gene

No Compound Related Data Available

Transcripts for KIAA1211 Gene

Unigene Clusters for KIAA1211 Gene

KIAA1211:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1211 Gene

No ASD Table

Relevant External Links for KIAA1211 Gene

GeneLoc Exon Structure for
KIAA1211
ECgene alternative splicing isoforms for
KIAA1211

Expression for KIAA1211 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA1211 Gene

mRNA differential expression in normal tissues according to GTEx for KIAA1211 Gene

This gene is overexpressed in Testis (x13.7).

Protein differential expression in normal tissues from HIPED for KIAA1211 Gene

This gene is overexpressed in Gallbladder (23.5), Peripheral blood mononuclear cells (17.5), and Fetal Brain (11.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA1211 Gene



NURSA nuclear receptor signaling pathways regulating expression of KIAA1211 Gene:

KIAA1211

SOURCE GeneReport for Unigene cluster for KIAA1211 Gene:

Hs.596667

Evidence on tissue expression from TISSUES for KIAA1211 Gene

  • Nervous system(3.6)
genes like me logo Genes that share expression patterns with KIAA1211: view

Primer Products

No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1211 Gene

Orthologs for KIAA1211 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1211 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1211 34 33
  • 99.41 (n)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA1211 33
  • 79.43 (n)
MGC148692 34
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1211 34
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia C530008M17Rik 34
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1211 34
  • 49 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1211 34
  • 31 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA1211 34
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1211 34
  • 72 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:dkeyp-117h8.2 34
  • 39 (a)
OneToOne
Species where no ortholog for KIAA1211 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1211 Gene

ENSEMBL:
Gene Tree for KIAA1211 (if available)
TreeFam:
Gene Tree for KIAA1211 (if available)

Paralogs for KIAA1211 Gene

Paralogs for KIAA1211 Gene

genes like me logo Genes that share paralogs with KIAA1211: view

Variants for KIAA1211 Gene

Sequence variations from dbSNP and Humsavar for KIAA1211 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000000888 -- 56,254,679(+) C/T genic_upstream_transcript_variant, intron_variant
rs1000016538 -- 56,295,969(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000017200 -- 56,302,751(+) C/T genic_upstream_transcript_variant, intron_variant
rs10000186 -- 56,213,176(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000023443 -- 56,181,032(+) G/A genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1211 Gene

Variant ID Type Subtype PubMed ID
dgv5212n100 CNV loss 25217958
dgv5213n100 CNV gain 25217958
esv2671346 CNV deletion 23128226
esv3569433 CNV loss 25503493
esv3600570 CNV loss 21293372
esv3600571 CNV gain 21293372
nsv1012036 CNV gain 25217958
nsv1161086 CNV duplication 26073780
nsv293732 CNV deletion 16902084
nsv518368 CNV loss 19592680
nsv818233 CNV gain 17921354
nsv829940 CNV gain 17160897

Variation tolerance for KIAA1211 Gene

Residual Variation Intolerance Score: 66.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.62; 98.27% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIAA1211 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1211

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1211 Gene

Disorders for KIAA1211 Gene

Additional Disease Information for KIAA1211

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for KIAA1211 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1211 Gene

Publications for KIAA1211 Gene

  1. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4 58
  2. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 2 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Exome Sequencing Identified CCER2 as a Novel Candidate Gene for Moyamoya Disease. (PMID: 27717682) Mukawa M … Akagawa H (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017) 4 58

Products for KIAA1211 Gene

Sources for KIAA1211 Gene

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