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Aliases for KIAA1191 Gene

Aliases for KIAA1191 Gene

  • KIAA1191 2 3
  • Flavin Monooxygenase Motif-Containing Protein Of 33 KDa 3 4
  • Brain-Derived Rescue Factor P60MONOX 3 4
  • Flavine Monooxygenase Motif-Containing Protein Of 33 KDa 3
  • Putative Monooxygenase P33MONOX 3
  • EC 1.-.-.- 4
  • P60MONOX 3
  • P33MONOX 4

External Ids for KIAA1191 Gene

Summaries for KIAA1191 Gene

GeneCards Summary for KIAA1191 Gene

KIAA1191 (KIAA1191) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity.

UniProtKB/Swiss-Prot for KIAA1191 Gene

  • Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1191 Gene

Genomics for KIAA1191 Gene

Genomic Location for KIAA1191 Gene

Start:
176,346,061 bp from pter
End:
176,361,968 bp from pter
Size:
15,908 bases
Orientation:
Minus strand

Genomic View for KIAA1191 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA1191 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1191 Gene

Regulatory Elements for KIAA1191 Gene

Proteins for KIAA1191 Gene

  • Protein details for KIAA1191 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96A73-P33MX_HUMAN
    Recommended name:
    Putative monooxygenase p33MONOX
    Protein Accession:
    Q96A73
    Secondary Accessions:
    • B2RD69
    • B8K1S6
    • Q6IA24
    • Q8NDU3
    • Q9BRE5
    • Q9H7D5
    • Q9ULM9

    Protein attributes for KIAA1191 Gene

    Size:
    305 amino acids
    Molecular mass:
    33247 Da
    Quaternary structure:
    • Interacts with COBRA1, NOL12 and PRNP.

    Alternative splice isoforms for KIAA1191 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA1191 Gene

Proteomics data for KIAA1191 Gene at MOPED

Post-translational modifications for KIAA1191 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KIAA1191 Gene

Domains for KIAA1191 Gene

Protein Domains for KIAA1191 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

P33MX_HUMAN
Family:
  • Belongs to the P33MONOX family.:
    • Q96A73
genes like me logo Genes that share domains with KIAA1191: view

No data available for Gene Families for KIAA1191 Gene

Function for KIAA1191 Gene

Molecular function for KIAA1191 Gene

UniProtKB/Swiss-Prot Function: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth

Enzyme Numbers (IUBMB) for KIAA1191 Gene

Gene Ontology (GO) - Molecular Function for KIAA1191 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with KIAA1191: view

Phenotypes for KIAA1191 Gene

genes like me logo Genes that share phenotypes with KIAA1191: view

miRNA for KIAA1191 Gene

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA1191 Gene

Localization for KIAA1191 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIAA1191 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1191 Gene COMPARTMENTS Subcellular localization image for KIAA1191 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for KIAA1191 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005737 cytoplasm ISS --
genes like me logo Genes that share ontologies with KIAA1191: view

Pathways for KIAA1191 Gene

SuperPathways for KIAA1191 Gene

No Data Available

Interacting Proteins for KIAA1191 Gene

Gene Ontology (GO) - Biological Process for KIAA1191 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with KIAA1191: view

No data available for Pathways by source for KIAA1191 Gene

Transcripts for KIAA1191 Gene

Unigene Clusters for KIAA1191 Gene

KIAA1191:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1191 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d · 12e
SP1: - - - - -
SP2: - - -
SP3: -
SP4: - - - - - - - - -
SP5: - - - - - -
SP6: - - - - - - - -
SP7: - - - - - - - -
SP8: - - - -
SP9: - - - - - - - - - - -
SP10: - - - -
SP11: - - - - - - - -
SP12: - - - - - - -
SP13: - - - - - - - - - -
SP14: - - - - - - - - -
SP15: - - -
SP16: - - - - - -
SP17: -
SP18: - - - - - - - - - - - -

Relevant External Links for KIAA1191 Gene

GeneLoc Exon Structure for
KIAA1191
ECgene alternative splicing isoforms for
KIAA1191

Expression for KIAA1191 Gene

mRNA expression in normal human tissues for KIAA1191 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for KIAA1191 Gene

SOURCE GeneReport for Unigene cluster for KIAA1191 Gene Hs.743257

mRNA Expression by UniProt/SwissProt for KIAA1191 Gene

Q96A73-P33MX_HUMAN
Tissue specificity: Down-regulated in the occipital lobe of an early stage Alzheimer disease patients.
genes like me logo Genes that share expressions with KIAA1191: view

Orthologs for KIAA1191 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1191 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1191 36
  • 99.45 (n)
  • 99.34 (a)
KIAA1191 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia P33MONOX 36
  • 86.56 (n)
  • 81.64 (a)
P33MONOX 37
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1191 36
  • 90.6 (n)
  • 88.2 (a)
KIAA1191 37
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4833439L19Rik 36
  • 84.71 (n)
  • 81.19 (a)
4833439L19Rik 16
4833439L19Rik 37
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 68 (a)
OneToMany
-- 37
  • 74 (a)
OneToMany
-- 37
  • 64 (a)
OneToMany
-- 37
  • 70 (a)
OneToMany
-- 37
  • 70 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1191 37
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC306766 36
  • 85.26 (n)
  • 81.19 (a)
chicken
(Gallus gallus)
Aves KIAA1191 36
  • 72.56 (n)
  • 69.96 (a)
KIAA1191 37
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1191 37
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1191 36
  • 68.94 (n)
  • 68.6 (a)
Str.245 36
zebrafish
(Danio rerio)
Actinopterygii zgc:123105 36
  • 63.96 (n)
  • 59.8 (a)
zgc:123105 37
  • 52 (a)
OneToOne
Species with no ortholog for KIAA1191:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1191 Gene

ENSEMBL:
Gene Tree for KIAA1191 (if available)
TreeFam:
Gene Tree for KIAA1191 (if available)

Paralogs for KIAA1191 Gene

genes like me logo Genes that share paralogs with KIAA1191: view

No data available for Paralogs for KIAA1191 Gene

Variants for KIAA1191 Gene

Sequence variations from dbSNP and Humsavar for KIAA1191 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs870669 -- 176,352,168(-) TTTTT(G/T)TTTTT intron-variant
rs870670 -- 176,352,102(-) CTTTA(A/G)TCTTA intron-variant
rs998319 -- 176,349,759(-) ACGCA(C/G)GAAAG intron-variant
rs2003207 -- 176,351,197(+) TTAGC(C/T)GGGTG intron-variant
rs2033197 -- 176,350,420(+) TTGAT(C/T)CTGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1191 Gene

Variant ID Type Subtype PubMed ID
nsv462549 CNV Gain 19166990
esv2648102 CNV Deletion 19546169

Relevant External Links for KIAA1191 Gene

HapMap Linkage Disequilibrium report
KIAA1191

Disorders for KIAA1191 Gene

Relevant External Links for KIAA1191

Genetic Association Database (GAD)
KIAA1191
genes like me logo Genes that share disorders with KIAA1191: view

No data available for UniProtKB/Swiss-Prot for KIAA1191 Gene

Publications for KIAA1191 Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4
  2. Brain site-specific gene expression analysis in Alzheimer's disease patients. (PMID: 17032350) Yokota T. … Heese K. (Eur. J. Clin. Invest. 2006) 3 4
  3. Characterizing the novel protein p33MONOX. (PMID: 21153684) Mishra M. … Heese K. (Mol. Cell. Biochem. 2011) 3 4
  4. Isolation and characterization of novel CAG repeat containing genes expressed in human brain. (PMID: 10565538) Zuehlke C. … Schwinger E. (DNA Seq. 1999) 2 3
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for KIAA1191 Gene

Sources for KIAA1191 Gene

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