Free for academic non-profit institutions. Other users need a Commercial license

Aliases for KIAA1161 Gene

Aliases for KIAA1161 Gene

  • KIAA1161 2 3
  • Uncharacterized Family 31 Glucosidase KIAA1161 3
  • EC 3.2.1.- 4
  • NET37 3

External Ids for KIAA1161 Gene

Summaries for KIAA1161 Gene

GeneCards Summary for KIAA1161 Gene

KIAA1161 (KIAA1161) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds.

UniProtKB/Swiss-Prot for KIAA1161 Gene

  • Putative glucosidase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1161 Gene

Genomics for KIAA1161 Gene

Genomic Location for KIAA1161 Gene

Start:
34,366,669 bp from pter
End:
34,377,093 bp from pter
Size:
10,425 bases
Orientation:
Minus strand

Genomic View for KIAA1161 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA1161 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1161 Gene

Regulatory Elements for KIAA1161 Gene

Proteins for KIAA1161 Gene

  • Protein details for KIAA1161 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NSJ0-K1161_HUMAN
    Recommended name:
    Uncharacterized family 31 glucosidase KIAA1161
    Protein Accession:
    Q6NSJ0
    Secondary Accessions:
    • Q5T587
    • Q5T588
    • Q9ULQ9

    Protein attributes for KIAA1161 Gene

    Size:
    714 amino acids
    Molecular mass:
    81087 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI15965.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI15966.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for KIAA1161 Gene

Proteomics data for KIAA1161 Gene at MOPED

Post-translational modifications for KIAA1161 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn240 and Asn250

Other Protein References for KIAA1161 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA1161 Gene

Domains for KIAA1161 Gene

Protein Domains for KIAA1161 Gene

UniProtKB/Swiss-Prot:

K1161_HUMAN
Family:
  • Belongs to the glycosyl hydrolase 31 family.:
    • Q6NSJ0
genes like me logo Genes that share domains with KIAA1161: view

No data available for Gene Families for KIAA1161 Gene

Function for KIAA1161 Gene

Molecular function for KIAA1161 Gene

UniProtKB/Swiss-Prot Function: Putative glucosidase.

Enzyme Numbers (IUBMB) for KIAA1161 Gene

Gene Ontology (GO) - Molecular Function for KIAA1161 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with KIAA1161: view

Phenotypes for KIAA1161 Gene

GenomeRNAi human phenotypes for KIAA1161:
genes like me logo Genes that share phenotypes with KIAA1161: view

miRNA for KIAA1161 Gene

miRTarBase miRNAs that target KIAA1161

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA1161 Gene

Localization for KIAA1161 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIAA1161 Gene

Membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1161 Gene COMPARTMENTS Subcellular localization image for KIAA1161 gene
Compartment Confidence
golgi apparatus 2
nucleus 2
plasma membrane 2
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for KIAA1161 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0031965 nuclear membrane IEA --
genes like me logo Genes that share ontologies with KIAA1161: view

Pathways for KIAA1161 Gene

SuperPathways for KIAA1161 Gene

No Data Available

Interacting Proteins for KIAA1161 Gene

Gene Ontology (GO) - Biological Process for KIAA1161 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005975 carbohydrate metabolic process IEA --
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IEA --
GO:0048741 skeletal muscle fiber development IEA --
GO:0051897 positive regulation of protein kinase B signaling IEA --
genes like me logo Genes that share ontologies with KIAA1161: view

No data available for Pathways by source for KIAA1161 Gene

Transcripts for KIAA1161 Gene

mRNA/cDNA for KIAA1161 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(106) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KIAA1161 Gene

KIAA1161:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1161 Gene

No ASD Table

Relevant External Links for KIAA1161 Gene

GeneLoc Exon Structure for
KIAA1161
ECgene alternative splicing isoforms for
KIAA1161

Expression for KIAA1161 Gene

mRNA expression in normal human tissues for KIAA1161 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA1161 Gene

This gene is overexpressed in Muscle - Skeletal (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KIAA1161 Gene

SOURCE GeneReport for Unigene cluster for KIAA1161 Gene Hs.522083

genes like me logo Genes that share expressions with KIAA1161: view

Orthologs for KIAA1161 Gene

This gene was present in the common ancestor of animals.

Orthologs for KIAA1161 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1161 36
  • 99.11 (n)
  • 99.3 (a)
KIAA1161 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA1161 36
  • 87.8 (n)
  • 94.11 (a)
dog
(Canis familiaris)
Mammalia KIAA1161 36
  • 87.19 (n)
  • 94.53 (a)
KIAA1161 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia AI464131 36
  • 84.76 (n)
  • 92.15 (a)
AI464131 16
AI464131 37
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1161 37
  • 75 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1309821 36
  • 85.09 (n)
  • 92.29 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 72 (a)
OneToMany
-- 37
  • 76 (a)
OneToMany
KIAA1161 36
  • 74.84 (n)
  • 75.78 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 72 (a)
OneToMany
-- 37
  • 64 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1161 36
  • 66.47 (n)
  • 71.79 (a)
Str.14314 36
zebrafish
(Danio rerio)
Actinopterygii LOC100537539 36
  • 63.39 (n)
  • 67.98 (a)
si:ch211-117c19.1 37
  • 64 (a)
OneToMany
si:dkey-228b2.5 37
  • 66 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003993 36
  • 51.86 (n)
  • 38.45 (a)
fruit fly
(Drosophila melanogaster)
Insecta tobi 37
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 41 (a)
OneToMany
-- 37
  • 41 (a)
OneToMany
-- 37
  • 41 (a)
OneToMany
-- 37
  • 39 (a)
OneToMany
Species with no ortholog for KIAA1161:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1161 Gene

ENSEMBL:
Gene Tree for KIAA1161 (if available)
TreeFam:
Gene Tree for KIAA1161 (if available)

Paralogs for KIAA1161 Gene

No data available for Paralogs for KIAA1161 Gene

Variants for KIAA1161 Gene

Sequence variations from dbSNP and Humsavar for KIAA1161 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs2526 -- 34,366,784(+) TTTGA(C/T)ATATG utr-variant-3-prime
rs12377 - 34,372,349(-) CCATC(A/C/G/T)GCCTG missense, reference
rs1134455 -- 34,369,064(-) CTCAT(C/G)AGAGC utr-variant-3-prime
rs2297776 - 34,372,933(-) CCAGA(A/T)CCCTC reference, missense
rs3205138 -- 34,370,416(-) TGGCC(A/C)TCTTT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for KIAA1161 Gene

Variant ID Type Subtype PubMed ID
nsv893037 CNV Gain 21882294
nsv831542 CNV Gain 17160897

Relevant External Links for KIAA1161 Gene

HapMap Linkage Disequilibrium report
KIAA1161

Disorders for KIAA1161 Gene

Relevant External Links for KIAA1161

Genetic Association Database (GAD)
KIAA1161
Human Genome Epidemiology (HuGE) Navigator
KIAA1161
genes like me logo Genes that share disorders with KIAA1161: view

No data available for UniProtKB/Swiss-Prot for KIAA1161 Gene

Publications for KIAA1161 Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4
  2. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PMID: 19204726) Chapuis J. … Lambert J.C. (Mol. Psychiatry 2009) 3 49
  3. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  4. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 3
  5. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4

Products for KIAA1161 Gene

Sources for KIAA1161 Gene

Back to Top

Content