KIAA1147 Gene
protein-coding GIFtS: 37
GCID: GC07M141356
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KIAA1147
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Aliases
for KIAA1147 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
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| KIAA11471 2 | | LCHN1 2 | | PRO25612 | | Predicted Protein Of HQ25612 | | Protein LCHN2 |
Export aliases for KIAA1147 gene to outside databasesPrevious GC identifers: GC07M141003 GC07M135653 |
Summaries
for KIAA1147 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: LCHN_HUMAN, A4D1U4Function: May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampusfollowing transient cerebral ischemia (By similarity)
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Genomic Views
for KIAA1147 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA1147 gene promoter:
AML1a GATA-3 Pbx1a Tal-1beta LCR-F1 HNF-1A POU2F1 POU2F1a HNF-1 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA1147
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1147 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34KIAA1147 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M141356: view genomic region
(about GC identifiers)
Start:
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141,356,528 bp from pter |
End:
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141,401,953 bp from pter |
Size:
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45,426 bases |
Orientation:
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minus strand |
2 alternative locations:
| Chr7-,CRA_TCAG 140,694,236-140,739,666 | Chr7-,PATCHES 141,353,524-141,398,952 |
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Proteins
for KIAA1147 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LCHN_HUMAN, A4D1U4 (See
protein sequence)Recommended Name: Protein LCHN Size: 455 amino acids; 51446 Da
Secondary accessions: Q9ULS3Explore the universe of human proteins at neXtProt for KIAA1147: NX_A4D1U4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A4D1U4
KIAA1147 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073861.1
ENSEMBL proteins: ENSP00000445768 ENSP00000418236
Human Recombinant Protein Products:
KIAA1147 Antibody Products:
Assay Products for KIAA1147: |
Protein
Domains /
Families
for KIAA1147 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIAA1147 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A4D1U4ProtoNet protein and cluster: A4D1U4 UniProtKB/Swiss-Prot: LCHN_HUMAN, A4D1U4Similarity: Belongs to the LCHN family |
Function
for KIAA1147 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LCHN_HUMAN, A4D1U4Function: May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampusfollowing transient cerebral ischemia (By similarity)
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1147
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1147 |
|
Pathways & Interactions
for KIAA1147 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1147
|
Drugs & Compounds
for KIAA1147 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for KIAA1147
Search CenterWatch for drugs/clinical trials and news about KIAA1147 / LCHN
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Transcripts
for KIAA1147 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for KIAA1147 gene: NM_001080392.1 Unigene Cluster for KIAA1147: KIAA1147 Hs.521240 [show with all ESTs]Unigene Representative Sequence: NM_0010803922 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000536163(uc003vwk.3) ENST00000482493
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1147 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1147
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIAA1147 (NM_001080392) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1147 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1147 |
Additional cDNA sequence: AB032973.2 AF116707.1 AF136629.1 BC012493.1 5 DOTS entries: DT.215982 DT.102842950 DT.121048454 DT.75103686 DT.95370845
GeneLoc Exon Structure
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Expression
for KIAA1147 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA1147 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATTTTTAAT
About this image
See KIAA1147 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA1147
SOURCE GeneReport for Unigene cluster: Hs.521240
SABiosciences Custom PCR Arrays for KIAA1147
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1147
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA1147 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1147 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1147 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1147 |
Orthologs
for KIAA1147 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for KIAA1147 gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for KIAA1147 (if available)
TreeFam Gene Tree for KIAA1147 (if available) |
Paralogs
for KIAA1147 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for KIAA1147 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for KIAA1147 (141356528 - 141401953 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for KIAA1147
2 CNVs: 47923 36624 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for KIAA1147 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIAA1147 for disorders About GeneDecksing
5  diseases for KIAA1147: About MalaCardstransient cerebral ischemia nevus ischemia cerebritis
neuronitis
Export disorders for KIAA1147 gene to outside databases
|
Publications
for KIAA1147 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA1147 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KIAA1147) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2 Hirosawa M.... Ohara O. (1999)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A germline-specific class of small RNAs binds mammali an Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (2006)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for KIAA1147 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA1147 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing KIAA1147 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA1147 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA1147 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for KIAA1147 gene:
Search GeneIP for patents involving KIAA1147
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA1147 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIAA1147 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1147 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for KIAA1147 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1147 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1147 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1147 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1147 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1147 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA1147 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1147 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1147 |
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 | | | KIAA1147 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1147 |
|  |  |  | | | | Search ThermoFisher Antibodies for KIAA1147 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1147 |
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