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Aliases for KIAA1143 Gene

Aliases for KIAA1143 Gene

  • KIAA1143 2 3

External Ids for KIAA1143 Gene

Previous GeneCards Identifiers for KIAA1143 Gene

  • GC03M043746
  • GC03M043970
  • GC03M044609
  • GC03M044755
  • GC03M044750

Summaries for KIAA1143 Gene

GeneCards Summary for KIAA1143 Gene

KIAA1143 (KIAA1143) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1143 Gene

Genomics for KIAA1143 Gene

Regulatory Elements for KIAA1143 Gene

Enhancers for KIAA1143 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around KIAA1143 on UCSC Golden Path with GeneCards custom track

Genomic Location for KIAA1143 Gene

Chromosome:
3
Start:
44,737,661 bp from pter
End:
44,761,697 bp from pter
Size:
24,037 bases
Orientation:
Minus strand

Genomic View for KIAA1143 Gene

Genes around KIAA1143 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1143 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1143 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1143 Gene

Proteins for KIAA1143 Gene

  • Protein details for KIAA1143 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96AT1-K1143_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1143
    Protein Accession:
    Q96AT1
    Secondary Accessions:
    • A8K0I4
    • Q96HJ8
    • Q9ULS7

    Protein attributes for KIAA1143 Gene

    Size:
    154 amino acids
    Molecular mass:
    17465 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KIAA1143 Gene

Post-translational modifications for KIAA1143 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1143 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA1143 Gene

Domains & Families for KIAA1143 Gene

Protein Domains for KIAA1143 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1143: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1143 Gene

Function for KIAA1143 Gene

Gene Ontology (GO) - Molecular Function for KIAA1143 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with KIAA1143: view

Phenotypes for KIAA1143 Gene

genes like me logo Genes that share phenotypes with KIAA1143: view

Animal Models for KIAA1143 Gene

MGI Knock Outs for KIAA1143:

Animal Model Products

CRISPR Products

miRNA for KIAA1143 Gene

miRTarBase miRNAs that target KIAA1143

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KIAA1143 Gene

Localization for KIAA1143 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1143 Gene COMPARTMENTS Subcellular localization image for KIAA1143 gene
Compartment Confidence
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1143 Gene

Pathways & Interactions for KIAA1143 Gene

SuperPathways for KIAA1143 Gene

No Data Available

Interacting Proteins for KIAA1143 Gene

Gene Ontology (GO) - Biological Process for KIAA1143 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1143 Gene

Drugs & Compounds for KIAA1143 Gene

No Compound Related Data Available

Transcripts for KIAA1143 Gene

mRNA/cDNA for KIAA1143 Gene

Unigene Clusters for KIAA1143 Gene

KIAA1143:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1143 Gene

No ASD Table

Relevant External Links for KIAA1143 Gene

GeneLoc Exon Structure for
KIAA1143
ECgene alternative splicing isoforms for
KIAA1143

Expression for KIAA1143 Gene

mRNA expression in normal human tissues for KIAA1143 Gene

Protein differential expression in normal tissues from HIPED for KIAA1143 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (23.7), Ovary (11.7), and Lymph node (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA1143 Gene



Protein tissue co-expression partners for KIAA1143 Gene

NURSA nuclear receptor signaling pathways regulating expression of KIAA1143 Gene:

KIAA1143

SOURCE GeneReport for Unigene cluster for KIAA1143 Gene:

Hs.744955
genes like me logo Genes that share expression patterns with KIAA1143: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KIAA1143 Gene

Orthologs for KIAA1143 Gene

This gene was present in the common ancestor of animals.

Orthologs for KIAA1143 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia KIAA1143 34
  • 91.77 (n)
  • 90.26 (a)
KIAA1143 35
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1143 34
  • 91.23 (n)
  • 91.45 (a)
KIAA1143 35
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1110059G10Rik 34
  • 88.1 (n)
  • 88.31 (a)
1110059G10Rik 16
1110059G10Rik 35
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC739627 34
  • 99.78 (n)
  • 100 (a)
KIAA1143 35
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1311745 34
  • 86.8 (n)
  • 87.66 (a)
oppossum
(Monodelphis domestica)
Mammalia KIAA1143 35
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1143 35
  • 61 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA1143 34
  • 62.12 (n)
  • 59.09 (a)
KIAA1143 35
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1143 35
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1143 34
  • 65.8 (n)
  • 60.13 (a)
Str.3626 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.7340 34
zebrafish
(Danio rerio)
Actinopterygii wufa20b03 34
zgc:77056 34
  • 63.51 (n)
  • 59.46 (a)
zgc:77056 35
  • 56 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG42245 34
  • 53.19 (n)
  • 46.81 (a)
CG42245 35
  • 43 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1575 35
  • 35 (a)
OneToOne
Species where no ortholog for KIAA1143 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1143 Gene

ENSEMBL:
Gene Tree for KIAA1143 (if available)
TreeFam:
Gene Tree for KIAA1143 (if available)

Paralogs for KIAA1143 Gene

Pseudogenes.org Pseudogenes for KIAA1143 Gene

genes like me logo Genes that share paralogs with KIAA1143: view

No data available for Paralogs for KIAA1143 Gene

Variants for KIAA1143 Gene

Sequence variations from dbSNP and Humsavar for KIAA1143 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
VAR_027272 -
rs3762 -- 44,748,956(+) CTTCT(A/G)TAACA utr-variant-3-prime
rs1058705 -- 44,748,810(+) TCACC(A/C/G/T)CTGTA utr-variant-3-prime
rs1141633 -- 44,749,914(-) TGCTC(A/G)GGAGG utr-variant-3-prime
rs1141637 -- 44,749,387(-) TTTTG(A/G)GACAG utr-variant-3-prime

Variation tolerance for KIAA1143 Gene

Residual Variation Intolerance Score: 85.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.02; 50.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA1143 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1143

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for KIAA1143 Gene

Disorders for KIAA1143 Gene

Relevant External Links for KIAA1143

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA1143

No disorders were found for KIAA1143 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1143 Gene

Publications for KIAA1143 Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 65
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  5. Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. (PMID: 24999758) Elzi D.J. … Shiio Y. (J. Proteome Res. 2014) 3 65

Products for KIAA1143 Gene

Sources for KIAA1143 Gene

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