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KIAA1109 Gene

protein-coding   GIFtS: 50
GCID: GC04P123073

KIAA1109

  See KIAA1109-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
KIAA11091 2     Tweek2
Fragile Site-Associated Protein2 3     Uncharacterized Protein KIAA11092
FSA2 3     KIAA13713
Fragile Site-Associated1     

External Ids:    HGNC: 269531   Entrez Gene: 841622   Ensembl: ENSG000001386887   OMIM: 6115655   UniProtKB: Q2LD373   

Export aliases for KIAA1109 gene to outside databases

Previous GC identifers: GC04P124135 GC04P123447 GC04P123564 GC04P123630 GC04P123528 GC04P123431 GC04P123311 GC04P118818


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KIAA1109 Gene:
This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac
disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and
adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that
plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial
growth and differentiation, and in tumor development. (provided by RefSeq, Oct 2009)

GeneCards Summary for KIAA1109 Gene:
KIAA1109 (KIAA1109) is a protein-coding gene. Diseases associated with KIAA1109 include celiac disease, and posterior uveitis.

Gene Wiki entry for KIAA1109 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KIAA1109 gene promoter:
         TBP   Bach2   Evi-1   S8   POU2F1   FOXJ2 (long isoform)   TFIID   POU2F1a   FOXJ2   MRF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for KIAA1109

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIAA1109


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q27   Ensembl cytogenetic band:  4q27   HGNC cytogenetic band: 4q28.1

KIAA1109 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIAA1109 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P123073:  view genomic region     (about GC identifiers)

Start:
123,073,488 bp from pter      End:
123,283,914 bp from pter
Size:
210,427 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: K1109_HUMAN, Q2LD37 (See protein sequence)
Recommended Name: Uncharacterized protein KIAA1109  
Size: 5005 amino acids; 555482 Da
Miscellaneous: KIAA1109 is mapped in the genomic region associated with susceptibility to celiac disease (CELIAC6)
Sequence caution: Sequence=AAH18094.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAH45783.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAI08275.1;
Type=Erroneous termination; Positions=4807; Note=Translated as Glu; Sequence=BAB15057.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened; Sequence=BAC85988.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened; Sequence=BAC87084.1; Type=Miscellaneous discrepancy; Note=Probable
cloning artifact;
Secondary accessions: Q4W598 Q5CZA9 Q6ZS70 Q6ZV75 Q86XA5 Q8WVD8 Q9H742 Q9NT48 Q9NTC3 Q9NTI4
Q9P2H6 Q9UPP3
Alternative splicing: 6 isoforms:  Q2LD37-1   Q2LD37-2   Q2LD37-4   Q2LD37-5   Q2LD37-6   Q2LD37-7   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIAA1109: NX_Q2LD37

Explore proteomics data for KIAA1109 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KIAA1109 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056127.2  
    ENSEMBL proteins: 
     ENSP00000264501   ENSP00000398039   ENSP00000413018   ENSP00000394909   ENSP00000393219  
     ENSP00000408229   ENSP00000410874   ENSP00000304374   ENSP00000397543   ENSP00000373390  
     ENSP00000389925  

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    antibodies-online proteins for KIAA1109 (2 products) 

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR018863 Fragile_site-assoc_C

    Graphical View of Domain Structure for InterPro Entry Q2LD37

    ProtoNet protein and cluster: Q2LD37


    Find genes that share domains with KIAA1109           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with KIAA1109           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for KIAA1109:
     G0/1 arrest  Increased G1 DNA content  Increased cell size 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KIAA1109

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    K1109_HUMAN, Q2LD37: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytoskeleton1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS17190194
    GO:0005739mitochondrion ----
    GO:0016020membrane NAS16632497
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with KIAA1109           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIAA1109
    Interactions:

        Search GeneGlobe Interaction Network for KIAA1109

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for KIAA1109 (Q2LD371, 3 ENSP000002645014) via UniProtKB, MINT, STRING, and/or I2D (see all 87)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1P352221, 3EBI-2683809,EBI-491549 I2D: score=1 
    SMAD2Q157963I2D: score=1 
    MRGBPENSP000003595184STRING: ENSP00000359518
    ALG8ENSP000002996264STRING: ENSP00000299626
    ELP3ENSP000002563984STRING: ENSP00000256398
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    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001558regulation of cell growth NAS17190194
    GO:0009235cobalamin metabolic process ----
    GO:0030856regulation of epithelial cell differentiation NAS17190194

    Find genes that share ontologies with KIAA1109           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KIAA1109 (K1109)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KIAA1109 gene (2 alternative transcripts): 
    NM_015312.3  NM_032202.1  

    Unigene Cluster for KIAA1109:

    KIAA1109
    Hs.408142  [show with all ESTs]
    Unigene Representative Sequence: DQ335469
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264501 ENST00000424425 ENST00000495260 ENST00000482114(uc003iej.1)
    ENST00000449251 ENST00000446180 ENST00000470182 ENST00000419325 ENST00000421930
    ENST00000438707(uc003iem.3) ENST00000306802 ENST00000480651 ENST00000483357
    ENST00000442707(uc003ien.3) ENST00000491933 ENST00000388738(uc003ieh.3)
    ENST00000455637(uc003iei.1 uc010ins.1 uc003iek.2 uc003iel.1)

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    hsa-miR-92a hsa-miR-513a-5p hsa-miR-27a hsa-miR-128 hsa-miR-25 hsa-miR-367 hsa-miR-3681* hsa-miR-32
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    Additional mRNA sequence: 

    AB029032.2 AK024043.1 AK025057.1 AK095216.1 AK124902.1 AK127686.1 AK127698.1 AK225886.1 
    AK303483.1 AK309063.1 AL137254.1 AL137384.1 AL137532.1 AL833461.1 BC018094.1 BC032408.1 
    BC045783.1 BC108274.1 CR936613.1 DQ335469.1 

    14 DOTS entries:

    DT.100781315  DT.453887  DT.97842981  DT.75199497  DT.101978677  DT.91766737  DT.101968924  DT.91766743 
    DT.121266629  DT.40200600  DT.70100312  DT.91683134  DT.97842979  DT.40128268 

    1 AceView cDNA sequence:

    AK129931 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1109 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^
    SP1:                                                                                                        -                                                   
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 24 ^ 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29a · 29b ^ 30 ^ 31 ^ 32a · 32b · 32c ^ 33 ^ 34 ^ 35a · 35b ^ 36a · 36b ^ 37a · 37b ^ 38a · 38b ^ 39 ^ 40a · 40b ^
    SP1:                                                        -                                               -                 -                             -   
    SP2:                                                                                                  -     -                 -                             -   
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                        -     -                                                                                             

    ExUns: 41 ^ 42 ^ 43 ^ 44 ^ 45 ^ 46a · 46b ^ 47 ^ 48 ^ 49 ^ 50a · 50b ^ 51 ^ 52 ^ 53
    SP1:                                                                                          
    SP2:                                                                                          
    SP3:                                                                                          
    SP4:                                                                                          
    SP5:                                                                                          


    ECgene alternative splicing isoforms for KIAA1109

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KIAA1109 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATAATGTAAA
    KIAA1109 Expression
    About this image

    KIAA1109 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIAA1109 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.408142

    UniProtKB/Swiss-Prot: K1109_HUMAN, Q2LD37
    Tissue specificity: Highly expressed in testis and ovary. Weakly or not expressed in other tissues

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for KIAA1109 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 4932438A13Rik1 , 5 RIKEN cDNA 4932438A13 gene1, 5 90.66(n)1
    96.65(a)1
      3 (18.30 cM)5
    2292271  NM_172679.21  NP_766267.21 
     368631215 
    chicken
    (Gallus gallus)
    Aves KIAA11091 KIAA1109 81.76(n)
    90.9(a)
      422670  XM_004941220.1  XP_004941277.1 
    lizard
    (Anolis carolinensis)
    Reptilia KIAA11096
    KIAA1109
    89(a)
    1 ↔ 1
    5(138723543-138858953)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.123752 Xenopus laevis transcribed sequence with moderate similarity more 78.98(n)    BU912829.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570932912   -- 71.84(n)   322823  57093291 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG48413
    tweek1
    tweek1 33(a)3
    48.85(n)1
    41.63(a)1
      36B43
    350261  NM_001201896.21  NP_001188825.21 
    worm
    (Caenorhabditis elegans)
    Secernentea Y47G6A.296
    Protein Y47G6A.29 (Y47G6A.29) mRNA, complete cds
    23(a)
    1 ↔ 1
    I(3578692-3600677) WBGene00021652
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CSF16
    Protein required for fermentation at low temperatu...
    18(a)
    1 ↔ 1
    XII(306855-315731) YLR087C


    ENSEMBL Gene Tree for KIAA1109 (if available)
    TreeFam Gene Tree for KIAA1109 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KIAA1109 (see all 3842)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs760704941,2
    untested1122903239(+) TTTTTC/TTTTCC 2 F syn10--------
    rs2002867961,2
    --118819208(+) GTTTT-/GTTTTT 1 -- int10--------
    rs791800541,2
    C--118819209(+) GTTTTG/TTTTTT 1 -- int10--------
    rs784446691,2
    C--118819224(+) TTTTTC/TTGAGG 1 -- int10--------
    rs105592461,2
    C--118827589(+) CATGT-/ACACACA 1 -- int10--------
    rs1397358071,2
    C--118830514(+) CTTGA-/CCTTCA 1 -- int10--------
    rs105892841,2
    C--118853205(+) CCCCT-/TCTCTCT 1 -- int10--------
    rs3700346031,2
    C--118853346(+) CACAT-/ACACACA 1 -- int10--------
    rs131317241,2
    C,F--118863649(+) tgtctG/Atctat 1 -- int15Minor allele frequency- A:0.40NA WA CSA 10
    rs1840989611,2
    --118863665(+) TATCTA/GTCTAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for KIAA1109 (123073488 - 123283914 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KIAA1109:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv4496CNV Insertion18451855
    nsv830045CNV Loss17160897

    Human Gene Mutation Database (HGMD): KIAA1109
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KIAA1109
    DNA2.0 Custom Variant and Variant Library Synthesis for KIAA1109

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611565    OMIM disorders: --

    2 diseases for KIAA1109:    
    About MalaCards
    celiac disease    posterior uveitis


    Find genes that share disorders with KIAA1109           About GenesLikeMe

    Genetic Association Database (GAD): KIAA1109
    Human Genome Epidemiology (HuGE) Navigator: KIAA1109 (7 documents)

    Export disorders for KIAA1109 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KIAA1109 gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with KIAA1109)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. (PubMed id 17558408)1, 2, 4 van Heel D.A.... Wijmenga C. (Nat. Genet. 2007)
    2. Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. (PubMed id 20197757)1, 4 JA1rgens M....Brand S. (Am. J. Gastroenterol. 2010)
    3. Multiple common variants for celiac disease influencing immune gene expression. (PubMed id 20190752)1, 4 Dubois P.C....van Heel D.A. (Nat. Genet. 2010)
    4. Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance. (PubMed id 20553587)1, 4 Hollis-Moffatt J.E....Merriman T.R. (amp 2010)
    5. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. (PubMed id 20453842)1, 4 Stahl E.A....Plenge R.M. (Nat. Genet. 2010)
    6. Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study. (PubMed id 19302705)1, 4 Teixeira V.H....Petit-Teixeira E. (amp 2009)
    7. Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. (PubMed id 19455118)1, 4 Glas J....Brand S. (Am. J. Gastroenterol. 2009)
    8. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. (PubMed id 19430480)1, 4 Barrett J.C....Rich S.S. (Nat. Genet. 2009)
    9. Newly identified genetic risk variants for celiac disease related to the immune response. (PubMed id 18311140)1, 4 Hunt K.A.... van Heel D.A. (Nat. Genet. 2008)
    10. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. (PubMed id 17554300)1, 4 (Nature 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84162 HGNC: 26953 AceView: KIAA1109.3 Ensembl:ENSG00000138688 euGenes: HUgn84162
    ECgene: KIAA1109 H-InvDB: KIAA1109

    (According to HUGE)
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    HUGE: KIAA1109

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KIAA1109 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KIAA1109 gene:
    Search GeneIP for patents involving KIAA1109

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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