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KIAA1109 Gene

protein-coding GIFtS: 50
GCID: GC04P123073

KIAA1109

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
KIAA1109¹ ²		Tweek²
Fragile Site-Associated Protein² ³		Uncharacterized Protein KIAA1109²
FSA² ³		KIAA1371³
Fragile Site-Associated¹

External Ids:	HGNC: 26953¹	Entrez Gene: 84162²	Ensembl: ENSG00000138688⁷	OMIM: 611565⁵	UniProtKB: Q2LD37³

Export aliases for KIAA1109 gene to outside databases

Previous GC identifers: GC04P124135 GC04P123447 GC04P123564 GC04P123630 GC04P123528 GC04P123431 GC04P123311 GC04P118818

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KIAA1109 Gene:

This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac

disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and

adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that

plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial

growth and differentiation, and in tumor development. (provided by RefSeq, Oct 2009)

GeneCards Summary for KIAA1109 Gene:

KIAA1109 (KIAA1109) is a protein-coding gene. Diseases associated with KIAA1109 include celiac disease, and posterior uveitis.

Gene Wiki entry for KIAA1109 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000004.12 NT_016354.20 NC_018915.2

Regulatory elements:

Regulatory transcription factor binding sites in the KIAA1109 gene promoter:
TBP Bach2 Evi-1 S8 POU2F1 FOXJ2 (long isoform) TFIID POU2F1a FOXJ2 MRF-2
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search Chromatin IP Primers for KIAA1109

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIAA1109

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q27 Ensembl cytogenetic band: 4q27 HGNC cytogenetic band: 4q28.1

KIAA1109 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIAA1109 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04P123073: view genomic region (about GC identifiers)

Start:	123,073,488 bp from pter	End:	123,283,914 bp from pter
Size:	210,427 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: K1109_HUMAN, Q2LD37 (See protein sequence)

Recommended Name: Uncharacterized protein KIAA1109

Size: 5005 amino acids; 555482 Da

Miscellaneous: KIAA1109 is mapped in the genomic region associated with susceptibility to celiac disease (CELIAC6)

Sequence caution: Sequence=AAH18094.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Sequence=AAH45783.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAI08275.1;

Type=Erroneous termination; Positions=4807; Note=Translated as Glu; Sequence=BAB15057.1; Type=Erroneous

initiation; Note=Translation N-terminally shortened; Sequence=BAC85988.1; Type=Erroneous initiation;

Note=Translation N-terminally shortened; Sequence=BAC87084.1; Type=Miscellaneous discrepancy; Note=Probable

cloning artifact;

Secondary accessions: Q4W598 Q5CZA9 Q6ZS70 Q6ZV75 Q86XA5 Q8WVD8 Q9H742 Q9NT48 Q9NTC3 Q9NTI4

Q9P2H6 Q9UPP3

Alternative splicing: 6 isoforms: Q2LD37-1 Q2LD37-2 Q2LD37-4 Q2LD37-5 Q2LD37-6 Q2LD37-7 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIAA1109: NX_Q2LD37

Explore proteomics data for KIAA1109 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See KIAA1109 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_056127.2

ENSEMBL proteins:

ENSP00000264501 ENSP00000398039 ENSP00000413018 ENSP00000394909 ENSP00000393219

ENSP00000408229 ENSP00000410874 ENSP00000304374 ENSP00000397543 ENSP00000373390

ENSP00000389925

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KIAA1109 Antibody Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:

IPR018863 Fragile_site-assoc_C

Graphical View of Domain Structure for InterPro Entry Q2LD37

ProtoNet protein and cluster: Q2LD37

KIAA1109 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--

KIAA1109 for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for KIAA1109:

G0/1 arrest

Increased G1 DNA content

Increased cell size

Animal Models:

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miRNA Products:		miRTarBase miRNAs that target KIAA1109: hsa-mir-335-5p (MIRT018363), hsa-mir-484 (MIRT041900), hsa-mir-615-3p (MIRT039681)

		Block miRNA regulation of human, mouse, rat KIAA1109 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate KIAA1109 (see all 11):
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In Situ Assay
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

K1109_HUMAN, Q2LD37: Membrane; Single-pass membrane protein (Potential)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	4
cytoskeleton	1
plasma membrane	1

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Gene Ontology (GO): 4 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	NAS	17190194
GO:0005739	mitochondrion	--	--
GO:0016020	membrane	NAS	16632497
GO:0016021	integral component of membrane	IEA	--

KIAA1109 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for KIAA1109
Interactions:

Search GeneGlobe Interaction Network for KIAA1109

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for KIAA1109 (Q2LD37^{1, 3} ENSP00000264501⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 87)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CTNNB1	P35222¹^,³	EBI-2683809,EBI-491549 I2D: score=1
SMAD2	Q15796³	I2D: score=1
MRGBP	ENSP00000359518⁴	STRING: ENSP00000359518
ALG8	ENSP00000299626⁴	STRING: ENSP00000299626
ELP3	ENSP00000256398⁴	STRING: ENSP00000256398

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Gene Ontology (GO): 3 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001558	regulation of cell growth	NAS	17190194
GO:0009235	cobalamin metabolic process	--	--
GO:0030856	regulation of epithelial cell differentiation	NAS	17190194

KIAA1109 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for KIAA1109 (K1109)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for KIAA1109 gene (2 alternative transcripts):

NM_015312.3 NM_032202.1

Unigene Cluster for KIAA1109:

KIAA1109

Hs.408142 [show with all ESTs]

Unigene Representative Sequence: DQ335469

17 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000264501 ENST00000424425 ENST00000495260 ENST00000482114(uc003iej.1)

ENST00000449251 ENST00000446180 ENST00000470182 ENST00000419325 ENST00000421930

ENST00000438707(uc003iem.3) ENST00000306802 ENST00000480651 ENST00000483357

ENST00000442707(uc003ien.3) ENST00000491933 ENST00000388738(uc003ieh.3)

ENST00000455637(uc003iei.1 uc010ins.1 uc003iek.2 uc003iel.1)

miRNA Products:		Block miRNA regulation of human, mouse, rat KIAA1109 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate KIAA1109 (see all 11):
		hsa-miR-92a hsa-miR-513a-5p hsa-miR-27a hsa-miR-128 hsa-miR-25 hsa-miR-367 hsa-miR-3681* hsa-miR-32

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Additional mRNA sequence:

AB029032.2 AK024043.1 AK025057.1 AK095216.1 AK124902.1 AK127686.1 AK127698.1 AK225886.1

AK303483.1 AK309063.1 AL137254.1 AL137384.1 AL137532.1 AL833461.1 BC018094.1 BC032408.1

BC045783.1 BC108274.1 CR936613.1 DQ335469.1

14 DOTS entries:

DT.100781315 DT.453887 DT.97842981 DT.75199497 DT.101978677 DT.91766737 DT.101968924 DT.91766743

DT.121266629 DT.40200600 DT.70100312 DT.91683134 DT.97842979 DT.40128268

1 AceView cDNA sequence:

AK129931

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1109 (see all 8) About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15a	·	15b	^	16	^	17	^	18	^	19	^	20	^	21	^	22	^	23	^
SP1:																																			-
SP2:
SP3:
SP4:
SP5:

ExUns:	24	^	25	^	26a	·	26b	^	27	^	28	^	29a	·	29b	^	30	^	31	^	32a	·	32b	·	32c	^	33	^	34	^	35a	·	35b	^	36a	·	36b	^	37a	·	37b	^	38a	·	38b	^	39	^	40a	·	40b	^
SP1:																			-																-						-										-
SP2:																																	-		-						-										-
SP3:
SP4:
SP5:																			-		-

ExUns:	41	^	42	^	43	^	44	^	45	^	46a	·	46b	^	47	^	48	^	49	^	50a	·	50b	^	51	^	52	^	53
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for KIAA1109

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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KIAA1109 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ATAATGTAAA

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KIAA1109 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

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KIAA1109 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.408142

UniProtKB/Swiss-Prot: K1109_HUMAN, Q2LD37

Tissue specificity: Highly expressed in testis and ovary. Weakly or not expressed in other tissues

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1109

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for KIAA1109 gene from Selected species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	4932438A13Rik^{1 , 5}	RIKEN cDNA 4932438A13 gene^{1, 5}	90.66(n)¹ 96.65(a)¹		3 (18.30 cM)⁵ 229227¹ NM_172679.2¹ NP_766267.2¹ 36863121⁵
chicken (Gallus gallus)	Aves	KIAA1109¹	KIAA1109	81.76(n) 90.9(a)		422670 XM_004941220.1 XP_004941277.1
lizard (Anolis carolinensis)	Reptilia	KIAA1109⁶	KIAA1109	89(a)	1 ↔ 1	5(138723543-138858953)
African clawed frog (Xenopus laevis)	Amphibia	Xl.12375²	Xenopus laevis transcribed sequence with moderate similarity more	78.98(n)		BU912829.1
zebrafish (Danio rerio)	Actinopterygii	57093291²	--	71.84(n)		322823 57093291
fruit fly (Drosophila melanogaster)	Insecta	CG4841³ tweek¹	tweek¹	33(a)³ 48.85(n)¹ 41.63(a)¹		36B4³ 35026¹ NM_001201896.2¹ NP_001188825.2¹
worm (Caenorhabditis elegans)	Secernentea	Y47G6A.29⁶	Protein Y47G6A.29 (Y47G6A.29) mRNA, complete cds	23(a)	1 ↔ 1	I(3578692-3600677) WBGene00021652
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	CSF1⁶	Protein required for fermentation at low temperatu...	18(a)	1 ↔ 1	XII(306855-315731) YLR087C

ENSEMBL Gene Tree for KIAA1109 (if available)
TreeFam Gene Tree for KIAA1109 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76070494^1,2		untested¹	122903239(+)	`TTTTTC/TTTTCC`	2	F	syn¹		0	--	--	--	--
rs200286796^1,2		--	118819208(+)	`GTTTT-/GTTTTT`	1	--	int¹		0	--	--	--	--
rs79180054^1,2	C	--	118819209(+)	`GTTTTG/TTTTTT`	1	--	int¹		0	--	--	--	--
rs78444669^1,2	C	--	118819224(+)	`TTTTTC/TTGAGG`	1	--	int¹		0	--	--	--	--
rs10559246^1,2	C	--	118827589(+)	`CATGT-/ACACACA`	1	--	int¹		0	--	--	--	--
rs139735807^1,2	C	--	118830514(+)	`CTTGA-/CCTTCA`	1	--	int¹		0	--	--	--	--
rs10589284^1,2	C	--	118853205(+)	`CCCCT-/TCTCTCT`	1	--	int¹		0	--	--	--	--
rs370034603^1,2	C	--	118853346(+)	`CACAT-/ACACACA`	1	--	int¹		0	--	--	--	--
rs13131724^1,2	C,F	--	118863649(+)	`tgtctG/Atctat`	1	--	int¹		5		NA WA CSA	10
rs184098961^1,2		--	118863665(+)	`TATCTA/GTCTAT`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for KIAA1109 (123073488 - 123283914 bp)

Structural Variations
Database of Genomic Variants (DGV) 2 variations for KIAA1109: About this table

Variant ID	Type	Subtype	PubMed ID
nsv4496	CNV	Insertion	18451855
nsv830045	CNV	Loss	17160897

Human Gene Mutation Database (HGMD): KIAA1109

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing KIAA1109

DNA2.0 Custom Variant and Variant Library Synthesis for KIAA1109

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611565 OMIM disorders: --

14 diseases for KIAA1109:
About MalaCards

celiac disease posterior uveitis color blindness uveitis

blindness polycystic kidney disease kidney disease fibrosarcoma

ulcerative colitis type 1 diabetes rheumatoid arthritis inflammatory bowel disease

arthritis malaria

KIAA1109 for disorders About GeneDecksing

Congresses - knowledge worth sharing:
The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
Genetic Association Database (GAD): KIAA1109
Human Genome Epidemiology (HuGE) Navigator: KIAA1109 (7 documents)

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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for KIAA1109 gene, integrated from 10 sources (see all 35):
(articles sorted by number of sources associating them with KIAA1109)

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A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. (PubMed id 17558408)^{1, 2, 4} van Heel D.A.... Wijmenga C. (Nat. Genet. 2007)
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. (PubMed id 20197757)^{1, 4} JA1rgens M....Brand S. (Am. J. Gastroenterol. 2010)
Multiple common variants for celiac disease influencing immune gene expression. (PubMed id 20190752)^{1, 4} Dubois P.C....van Heel D.A. (Nat. Genet. 2010)
Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance. (PubMed id 20553587)^{1, 4} Hollis-Moffatt J.E....Merriman T.R. (amp 2010)
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. (PubMed id 20453842)^{1, 4} Stahl E.A....Plenge R.M. (Nat. Genet. 2010)
Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study. (PubMed id 19302705)^{1, 4} Teixeira V.H....Petit-Teixeira E. (amp 2009)
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. (PubMed id 19455118)^{1, 4} Glas J....Brand S. (Am. J. Gastroenterol. 2009)
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. (PubMed id 19430480)^{1, 4} Barrett J.C....Rich S.S. (Nat. Genet. 2009)
Newly identified genetic risk variants for celiac disease related to the immune response. (PubMed id 18311140)^{1, 4} Hunt K.A.... van Heel D.A. (Nat. Genet. 2008)
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. (PubMed id 17554300)^{1, 4} (Nature 2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84162	HGNC: 26953	AceView: KIAA1109.3	Ensembl:ENSG00000138688	euGenes: HUgn84162
ECgene: KIAA1109	H-InvDB: KIAA1109

(According to HUGE)
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HUGE: KIAA1109

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for KIAA1109	Pharmacogenomics, SNPs, Pathways

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Patent Information for KIAA1109 gene:
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