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Aliases for KIAA1107 Gene

Aliases for KIAA1107 Gene

  • KIAA1107 2 3

External Ids for KIAA1107 Gene

Previous GeneCards Identifiers for KIAA1107 Gene

  • GC01M093020
  • GC01P091832
  • GC01P091972
  • GC01P092104
  • GC01P092344
  • GC01P092407
  • GC01P092632
  • GC01P090752

Summaries for KIAA1107 Gene

GeneCards Summary for KIAA1107 Gene

KIAA1107 (KIAA1107) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1107 Gene

Genomics for KIAA1107 Gene

Regulatory Elements for KIAA1107 Gene

Enhancers for KIAA1107 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G092365 1.2 ENCODE 23.3 +199.3 199291 1.6 CREB3L1 MLX AGO1 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 SP3 SNORA66 KIAA1107 SNORD21 CCDC18-AS1 EVI5 DR1 RPAP2 FAM69A GC01P092398
GH01G091608 1.2 Ensembl ENCODE 19.6 -556.4 -556445 4.1 ZFP64 RAD21 BRCA1 ZNF335 EGR1 RCOR1 FOS EGR2 ZNF680 ZNF654 KIAA1107 GFI1 GC01P091601 HSP90B3P
GH01G093078 1.2 ENCODE 14.2 +913.5 913451 4.5 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 CCDC18-AS1 SNORA66 SNORD21 TRR-TCT1-1 RPL5 KIAA1107 DNTTIP2 CCDC18 TMED5 RPAP2
GH01G092975 1.5 FANTOM5 ENCODE dbSUPER 10.4 +809.4 809425 5.3 HDGF ATF1 PKNOX1 MLX ZFP64 E2F7 TCF12 ZNF121 ZNF766 GATA2 RPL5 TRR-TCT1-1 DNTTIP2 ENSG00000230439 MTF2 EVI5 KIAA1107 SNORD21 FAM69A CCDC18-AS1
GH01G092831 1.2 ENCODE 10.9 +666.4 666444 4.2 MLX CREB3L1 AGO1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SNORA66 SNORD21 CCDC18-AS1 KIAA1107 RPL5 RPAP2 DR1 ENSG00000230439 FAM69A GC01P092832
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around KIAA1107 on UCSC Golden Path with GeneCards custom track

Genomic Location for KIAA1107 Gene

Chromosome:
1
Start:
92,166,985 bp from pter
End:
92,184,723 bp from pter
Size:
17,739 bases
Orientation:
Plus strand

Genomic View for KIAA1107 Gene

Genes around KIAA1107 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1107 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1107 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1107 Gene

Proteins for KIAA1107 Gene

  • Protein details for KIAA1107 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UPP5-K1107_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1107
    Protein Accession:
    Q9UPP5
    Secondary Accessions:
    • O14767
    • Q8N3X7

    Protein attributes for KIAA1107 Gene

    Size:
    1409 amino acids
    Molecular mass:
    155681 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC28132.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA1107 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA1107 Gene

Post-translational modifications for KIAA1107 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1107 Gene

No data available for DME Specific Peptides for KIAA1107 Gene

Domains & Families for KIAA1107 Gene

Protein Domains for KIAA1107 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1107: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1107 Gene

Function for KIAA1107 Gene

Phenotypes for KIAA1107 Gene

GenomeRNAi human phenotypes for KIAA1107:
genes like me logo Genes that share phenotypes with KIAA1107: view

Animal Model Products

CRISPR Products

miRNA for KIAA1107 Gene

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1107 Gene

Localization for KIAA1107 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA1107 gene
Compartment Confidence
nucleus 3
plasma membrane 2
cytosol 2
golgi apparatus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1107 Gene

Pathways & Interactions for KIAA1107 Gene

SuperPathways for KIAA1107 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA1107 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1107 Gene

Drugs & Compounds for KIAA1107 Gene

No Compound Related Data Available

Transcripts for KIAA1107 Gene

mRNA/cDNA for KIAA1107 Gene

Unigene Clusters for KIAA1107 Gene

KIAA1107:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1107 Gene

No ASD Table

Relevant External Links for KIAA1107 Gene

GeneLoc Exon Structure for
KIAA1107
ECgene alternative splicing isoforms for
KIAA1107

Expression for KIAA1107 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA1107 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA1107 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x5.5), Brain - Cortex (x5.3), and Brain - Anterior cingulate cortex (BA24) (x4.1).

Protein differential expression in normal tissues from HIPED for KIAA1107 Gene

This gene is overexpressed in Monocytes (25.0), Plasma (23.3), and Frontal cortex (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA1107 Gene



Protein tissue co-expression partners for KIAA1107 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of KIAA1107 Gene:

KIAA1107

SOURCE GeneReport for Unigene cluster for KIAA1107 Gene:

Hs.21554

Evidence on tissue expression from TISSUES for KIAA1107 Gene

  • Nervous system(3.1)
genes like me logo Genes that share expression patterns with KIAA1107: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1107 Gene

Orthologs for KIAA1107 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1107 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1107 34 35
  • 99.34 (n)
dog
(Canis familiaris)
Mammalia KIAA1107 34 35
  • 88.72 (n)
rat
(Rattus norvegicus)
Mammalia LOC100364240 34
  • 73.18 (n)
mouse
(Mus musculus)
Mammalia A830010M20Rik 34 16 35
  • 73.09 (n)
cow
(Bos Taurus)
Mammalia BTBD8 35
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1107 35
  • 52 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1107 35
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA1107 34 35
  • 67.39 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA1107 35
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1107 34
  • 56.62 (n)
Str.17169 34
zebrafish
(Danio rerio)
Actinopterygii si:ch73-389b16.2 35
  • 26 (a)
OneToOne
Species where no ortholog for KIAA1107 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1107 Gene

ENSEMBL:
Gene Tree for KIAA1107 (if available)
TreeFam:
Gene Tree for KIAA1107 (if available)

Paralogs for KIAA1107 Gene

No data available for Paralogs for KIAA1107 Gene

Variants for KIAA1107 Gene

Sequence variations from dbSNP and Humsavar for KIAA1107 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000236366 -- 92,169,589(+) ATCAA(A/C)ATAAA intron-variant
rs1000389803 -- 92,176,070(+) TGCAG(A/G)TGTAG intron-variant
rs1000539446 -- 92,169,855(+) ATGAT(A/G)GTGTA intron-variant
rs1000621722 -- 92,183,811(+) AACTC(A/T)GAGGG intron-variant
rs1000817977 -- 92,169,347(+) CCTTT(G/T)TAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1107 Gene

Variant ID Type Subtype PubMed ID
esv2714684 CNV deletion 23290073
nsv1113149 CNV deletion 24896259
nsv546821 CNV gain 21841781

Variation tolerance for KIAA1107 Gene

Gene Damage Index Score: 5.21; 69.89% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA1107 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1107

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1107 Gene

Disorders for KIAA1107 Gene

Relevant External Links for KIAA1107

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA1107

No disorders were found for KIAA1107 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1107 Gene

Publications for KIAA1107 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 2 3 4 64
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  3. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3 64
  4. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PMID: 17525332) Matsuoka S. … Elledge S.J. (Science 2007) 4 64
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64

Products for KIAA1107 Gene

Sources for KIAA1107 Gene

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