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Aliases for KIAA1045 Gene

Aliases for KIAA1045 Gene

  • KIAA1045 2 3
  • DNAJB5 6
  • HSC40 6

External Ids for KIAA1045 Gene

Previous GeneCards Identifiers for KIAA1045 Gene

  • GC09P035270
  • GC09P035127
  • GC09P034948
  • GC09P034947
  • GC09P034913

Summaries for KIAA1045 Gene

GeneCards Summary for KIAA1045 Gene

KIAA1045 (KIAA1045) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1045 Gene

Genomics for KIAA1045 Gene

Regulatory Elements for KIAA1045 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KIAA1045 Gene

Start:
34,957,487 bp from pter
End:
34,982,544 bp from pter
Size:
25,058 bases
Orientation:
Plus strand

Genomic View for KIAA1045 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA1045 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1045 Gene

Proteins for KIAA1045 Gene

  • Protein details for KIAA1045 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UPV7-K1045_HUMAN
    Recommended name:
    Protein KIAA1045
    Protein Accession:
    Q9UPV7
    Secondary Accessions:
    • B7Z253
    • Q58FE9
    • Q5T662

    Protein attributes for KIAA1045 Gene

    Size:
    400 amino acids
    Molecular mass:
    45192 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA82997.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for KIAA1045 Gene

neXtProt entry for KIAA1045 Gene

Proteomics data for KIAA1045 Gene at MOPED

Post-translational modifications for KIAA1045 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1045 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA1045 Gene

Domains for KIAA1045 Gene

Protein Domains for KIAA1045 Gene

Suggested Antigen Peptide Sequences for KIAA1045 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UPV7

UniProtKB/Swiss-Prot:

K1045_HUMAN :
  • Q9UPV7
Similarity:
  • Contains 1 PHD-type zinc finger.
genes like me logo Genes that share domains with KIAA1045: view

No data available for Gene Families for KIAA1045 Gene

Function for KIAA1045 Gene

Gene Ontology (GO) - Molecular Function for KIAA1045 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with KIAA1045: view

Animal Model Products

CRISPR Products

miRNA for KIAA1045 Gene

miRTarBase miRNAs that target KIAA1045

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KIAA1045

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA1045 Gene

Localization for KIAA1045 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1045 Gene COMPARTMENTS Subcellular localization image for KIAA1045 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1045 Gene

Pathways for KIAA1045 Gene

SuperPathways for KIAA1045 Gene

No Data Available

Interacting Proteins for KIAA1045 Gene

Gene Ontology (GO) - Biological Process for KIAA1045 Gene

None

No data available for Pathways by source for KIAA1045 Gene

Transcripts for KIAA1045 Gene

Unigene Clusters for KIAA1045 Gene

KIAA1045:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KIAA1045

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for KIAA1045

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1045 Gene

No ASD Table

Relevant External Links for KIAA1045 Gene

GeneLoc Exon Structure for
KIAA1045
ECgene alternative splicing isoforms for
KIAA1045

Expression for KIAA1045 Gene

mRNA expression in normal human tissues for KIAA1045 Gene

mRNA differential expression in normal tissues according to GTEx for KIAA1045 Gene

This gene is overexpressed in Brain - Cortex (9.9), Brain - Frontal Cortex (BA9) (8.3), Brain - Anterior cingulate cortex (BA24) (8.0), and Brain - Amygdala (4.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for KIAA1045 Gene

SOURCE GeneReport for Unigene cluster for KIAA1045 Gene Hs.7989

genes like me logo Genes that share expressions with KIAA1045: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for KIAA1045 Gene

Orthologs for KIAA1045 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1045 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1045 35
  • 99.17 (n)
  • 99.25 (a)
KIAA1045 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA1045 35
  • 88.83 (n)
  • 92.5 (a)
KIAA1045 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1045 35
  • 90.92 (n)
  • 93.75 (a)
KIAA1045 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia N28178 35
  • 88.15 (n)
  • 90.36 (a)
N28178 16
N28178 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1045 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 66 (a)
OneToMany
-- 36
  • 60 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia RGD1559864 35
  • 88.5 (n)
  • 91 (a)
chicken
(Gallus gallus)
Aves KIAA1045 35
  • 73.45 (n)
  • 72.77 (a)
KIAA1045 36
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1045 36
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1045 35
  • 67.34 (n)
  • 65.66 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC558943 35
  • 60.93 (n)
  • 54.43 (a)
si:ch211-269m17.1 36
  • 53 (a)
OneToOne
Species with no ortholog for KIAA1045:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1045 Gene

ENSEMBL:
Gene Tree for KIAA1045 (if available)
TreeFam:
Gene Tree for KIAA1045 (if available)

Paralogs for KIAA1045 Gene

No data available for Paralogs for KIAA1045 Gene

Variants for KIAA1045 Gene

Sequence variations from dbSNP and Humsavar for KIAA1045 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1061677 -- 34,982,017(+) CAGAA(A/T)TTCGG utr-variant-3-prime, intron-variant
rs2297647 -- 34,977,762(-) TTGGA(A/G)CCTGG intron-variant
rs2297648 -- 34,976,807(-) AATCT(A/G)CCCAG intron-variant
rs2298311 -- 34,979,938(-) CCTGC(A/G)CTTTC utr-variant-3-prime, nc-transcript-variant
rs2381208 -- 34,981,984(+) TTTGG(C/G)AACCT utr-variant-3-prime, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1045 Gene

Variant ID Type Subtype PubMed ID
nsv824912 CNV Gain 20364138
esv21645 CNV Loss 19812545

Relevant External Links for KIAA1045 Gene

HapMap Linkage Disequilibrium report
KIAA1045

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1045 Gene

Disorders for KIAA1045 Gene

No disorders were found for KIAA1045 Gene.

No data available for UniProtKB/Swiss-Prot for KIAA1045 Gene

Publications for KIAA1045 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 2 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 4
  5. Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system. (PMID: 20213681) Suzuki T. … Utsumi T. (Proteomics 2010) 4

Products for KIAA1045 Gene

Sources for KIAA1045 Gene

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