KIAA0947 Gene
protein-coding GIFtS: 37
GCID: GC05P005420
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KIAA0947
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Aliases
for KIAA0947 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KIAA09471 2 | | Uncharacterized Protein KIAA09472 |
Export aliases for KIAA0947 gene to outside databasesPrevious GC identifers: GC05P005601 GC05P005493 GC05P005474 GC05P005437 GC05P005475 |
Summaries
for KIAA0947 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KIAA0947 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA0947 gene promoter:
AhR p53 FOXJ2 (long isoform) STAT3 FOXJ2 YY1 Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA0947
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0947 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p15.32 Ensembl cytogenetic band: 5p15.32 HGNC cytogenetic band: 5p15KIAA0947 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P005420: view genomic region
(about GC identifiers)
Start:
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5,420,777 bp from pter |
End:
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5,490,347 bp from pter |
Size:
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69,571 bases |
Orientation:
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plus strand |
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Proteins
for KIAA0947 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: K0947_HUMAN, Q9Y2F5 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA0947 Size: 2266 amino acids; 247891 Da
Sequence caution: Sequence=BAA76791.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=BAC86755.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing; Sequence=CAB70661.1; Type=Erroneousinitiation; Note=Translation N-terminally extended; Sequence=CAB70661.1; Type=Erroneous termination; Positions=2051;Note=Translated as Gln;
Secondary accessions: Q68DE1 Q6ZT40 Q7L587 Q7Z3A9 Q9NTH9Explore the universe of human proteins at neXtProt for KIAA0947: NX_Q9Y2F5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2F5
KIAA0947 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056140.1
ENSEMBL proteins: ENSP00000296564
Human Recombinant Protein Products for KIAA0947:
KIAA0947 Antibody Products:
Assay Products for KIAA0947: |
Protein
Domains /
Families
for KIAA0947 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9Y2F5 |
Function
for KIAA0947 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0947 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0947
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KIAA0947 (NM_015325) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA0947 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA0947 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0947 |
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Pathways & Interactions
for KIAA0947 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA0947
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/10 Interacting proteins for KIAA0947 (Q9Y2F52, 3 ENSP000002965644) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
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Drugs & Compounds
for KIAA0947 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA0947
Search CenterWatch for drugs/clinical trials and news about KIAA0947 / K0947
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Transcripts
for KIAA0947 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for KIAA0947 gene: NM_015325.2 Unigene Cluster for KIAA0947: KIAA0947 Hs.449296 [show with all ESTs]Unigene Representative Sequence: NM_0153253 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000512608 ENST00000296564(uc003jdm.4) ENST00000505464
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0947 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0947
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIAA0947 (NM_015325) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA0947 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA0947 |
Additional cDNA sequence: AB023164.3 AK024400.1 AK025279.1 AK095073.1 AK096615.1 AK130025.1 AL137260.1 AL832204.1 BC004902.2 BC041002.2 BX538020.1 CR749441.1 8 DOTS entries: DT.314743 DT.92429569 DT.101981446 DT.101955547 DT.120861410 DT.100777475 DT.40302217 DT.95363634 24/128 AceView cDNA sequences (see all 128): AL832204 AI918362 CA432431 CA388756 BM976435 AA938202 BM663707 CR749441 W74670 AK130025 AI470095 AI339461 N72874 AA557152 AI697136 AA447230 BQ447128 AA716553 AI362241 AI373422 AI148165 BU620442 AL137260 BM008307
GeneLoc Exon Structure
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Expression
for KIAA0947 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA0947 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTTTGATTT
About this image
See KIAA0947 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA0947
SOURCE GeneReport for Unigene cluster: Hs.449296
SABiosciences Custom PCR Arrays for KIAA0947
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA0947
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA0947 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0947 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0947 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0947 |
Orthologs
for KIAA0947 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for KIAA0947 gene from 4/11 species (see all 11) About this table
ENSEMBL Gene Tree for KIAA0947 (if available)
TreeFam Gene Tree for KIAA0947 (if available) |
Paralogs
for KIAA0947 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for KIAA0947 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for KIAA0947 (5420777 - 5490347 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KIAA0947
1 CNV: 3540 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA0947 |
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Disorders
/ Diseases
for KIAA0947 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for KIAA0947 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA0947 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with KIAA0947) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
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External Searches for KIAA0947 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA0947 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing KIAA0947 gene
(According to HUGE)
About This Section
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Specialized Databases showing KIAA0947 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA0947 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for KIAA0947 gene:
Search GeneIP for patents involving KIAA0947
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA0947 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIAA0947 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIAA0947 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA0947 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIAA0947 | | OriGene 3'-UTR Clone for KIAA0947 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0947 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0947 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KIAA0947 | | OriGene Custom Protein Services for KIAA0947 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA0947 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA0947 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0947 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA0947 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0947 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0947 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0947 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for KIAA0947 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA0947 |
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