KIAA0930 Gene
protein-coding GIFtS: 47
GCID: GC22M045589
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KIAA0930(Previous name: chromosome 22 open reading frame 9 )
(Previous symbol: C22orf9)
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Aliases
for KIAA0930 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KIAA09301 2 | | C22orf91 2 3 | | BK268H5.C22.11 | | Chromosome 22 Open Reading Frame 91 | | Uncharacterized Protein KIAA09302 |
Export aliases for KIAA0930 gene to outside databasesPrevious GC identifers: GC22M042225 GC22M043866 GC22M043868 |
Summaries
for KIAA0930 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for KIAA0930 (C22orf9)
|
Genomic Views
for KIAA0930 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for KIAA0930
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA0930
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0930 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.31 Ensembl cytogenetic band: 22q13.31 HGNC cytogenetic band: 22q13.31KIAA0930 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M045589: view genomic region
(about GC identifiers)
Start:
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45,588,114 bp from pter |
End:
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45,636,650 bp from pter |
Size:
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48,537 bases |
Orientation:
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minus strand |
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Proteins
for KIAA0930 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: K0930_HUMAN, Q6ICG6 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA0930 Size: 404 amino acids; 45794 Da
Secondary accessions: B0QY17 B0QY19 B3KT48 Q6ZVE5 Q7Z6K9 Q8IZ76 Q9Y2E2Alternative splicing: 3 isoforms: Q6ICG6-1 Q6ICG6-2 Q6ICG6-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KIAA0930: NX_Q6ICG6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ICG6
KIAA0930 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001009880.1 NP_056079.1
ENSEMBL proteins: ENSP00000336720 ENSP00000399125 ENSP00000251993 ENSP00000375485 ENSP00000402514 ENSP00000403030 ENSP00000392752 ENSP00000395994 ENSP00000389482
Human Recombinant Protein Products:
KIAA0930 Antibody Products:
Assay Products for KIAA0930: |
Protein
Domains /
Families
for KIAA0930 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIAA0930 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6ICG6ProtoNet protein and cluster: Q6ICG6 |
Function
for KIAA0930 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
Genatlas biochemistry entry for KIAA0930:related to C elegans cos C16E9
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0930 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0930 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): KIAA0930 (NM_015264) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA0930 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0930 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0930 |
|
Pathways & Interactions
for KIAA0930 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA0930
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/7 Interacting proteins for KIAA0930 (Q6ICG62, 3 ENSP000002519934) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
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Drugs & Compounds
for KIAA0930 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA0930
Search CenterWatch for drugs/clinical trials and news about KIAA0930 / K0930
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Transcripts
for KIAA0930 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIAA0930 gene (2 alternative transcripts): NM_001009880.1 NM_015264.1 Unigene Cluster for KIAA0930: KIAA0930 Hs.592207 [show with all ESTs]Unigene Representative Sequence: NM_01526417 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000336156(uc010gzw.1 uc003bfv.1 uc003bfw.1 uc010gzx.2 uc003bfx.1)
ENST00000423262 ENST00000251993 ENST00000391627 ENST00000488038 ENST00000483374
ENST00000498418 ENST00000474515 ENST00000493003 ENST00000440039 ENST00000414854
ENST00000424508 ENST00000486640 ENST00000417906 ENST00000496226 ENST00000492273
ENST00000443310
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0930 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0930 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): KIAA0930 (NM_015264) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA0930 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0930 |
Additional cDNA sequence: AB023147.1 AK025608.1 AK094359.1 AK094937.1 AK124648.1 AK297058.1 AK309015.1 AK315883.1 AY007105.1 BC016882.1 BC038414.1 BC053595.1 CR456402.1 DQ457059.1 19 DOTS entries: DT.215051 DT.92436606 DT.95322913 DT.97794418 DT.100790105 DT.313359 DT.313358 DT.97847001 DT.95203221 DT.120638263 DT.100730688 DT.102829442 DT.95297964 DT.100790104 DT.120638257 DT.40200470 DT.40210546 DT.95203222 DT.100790103 24/276 AceView cDNA sequences (see all 276): BQ712211 CF137188 CB156602 BM552972 BM662340 AA831180 BU729650 AI129781 BM915770 BC038414 BQ070790 BC016882 BM666701 AI868746 BM811337 BF869096 AK025608 CD364996 BQ690687 BM551945 AK094937 AL138419 AB023147 AW136605
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0930 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | ^ |
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| SP1: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | |
| SP3: | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | |
| SP5: | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18a | · | 18b | ^ | 19a | · | 19b | · | 19c |
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| SP1: | - | | | | | | | | | | |
| SP2: | - | | | | | | | | | | |
| SP3: | - | | | | | | | | | | |
| SP4: | - | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for KIAA0930
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Expression
for KIAA0930 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA0930 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGGCGTTTC
About this image
See KIAA0930 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA0930
SOURCE GeneReport for Unigene cluster: Hs.592207
SABiosciences Custom PCR Arrays for KIAA0930
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA0930
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA0930 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0930 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0930 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0930 |
Orthologs
for KIAA0930 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KIAA0930 gene from 9/21 species (see all 21) About this table
ENSEMBL Gene Tree for KIAA0930 (if available)
TreeFam Gene Tree for KIAA0930 (if available) |
Paralogs
for KIAA0930 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KIAA0930 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for KIAA0930 (45588114 - 45636650 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KIAA0930: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA0930 |
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Disorders
/ Diseases
for KIAA0930 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for KIAA0930 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA0930 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with KIAA0930) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
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External Searches for KIAA0930 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIAA0930 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIAA0930 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA0930 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA0930 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KIAA0930 gene:
Search GeneIP for patents involving KIAA0930
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA0930 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIAA0930 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIAA0930 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA0930 | | | OriGene Protein Over-expression Lysate for KIAA0930 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIAA0930 | | OriGene 3'-UTR Clone for KIAA0930 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0930 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA0930 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KIAA0930 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KIAA0930 | | OriGene Custom Protein Services for KIAA0930 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA0930 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA0930 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0930 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA0930 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0930 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0930 |
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 | | | KIAA0930 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0930 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0930 |
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