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Aliases for KIAA0930 Gene

Aliases for KIAA0930 Gene

  • KIAA0930 2 3
  • C22orf9 3 4
  • Chromosome 22 Open Reading Frame 9 2
  • LSC3 3

External Ids for KIAA0930 Gene

Previous HGNC Symbols for KIAA0930 Gene

  • C22orf9

Previous GeneCards Identifiers for KIAA0930 Gene

  • GC22M042225
  • GC22M043866
  • GC22M043868
  • GC22M045589

Summaries for KIAA0930 Gene

GeneCards Summary for KIAA0930 Gene

KIAA0930 (KIAA0930) is a Protein Coding gene.

Gene Wiki entry for KIAA0930 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0930 Gene

Genomics for KIAA0930 Gene

Regulatory Elements for KIAA0930 Gene

Promoters for KIAA0930 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around KIAA0930 on UCSC Golden Path with GeneCards custom track

Genomic Location for KIAA0930 Gene

Chromosome:
22
Start:
45,190,338 bp from pter
End:
45,240,769 bp from pter
Size:
50,432 bases
Orientation:
Minus strand

Genomic View for KIAA0930 Gene

Genes around KIAA0930 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0930 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0930 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0930 Gene

Proteins for KIAA0930 Gene

  • Protein details for KIAA0930 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ICG6-K0930_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0930
    Protein Accession:
    Q6ICG6
    Secondary Accessions:
    • B0QY17
    • B0QY19
    • B3KT48
    • Q6ZVE5
    • Q7Z6K9
    • Q8IZ76
    • Q9Y2E2

    Protein attributes for KIAA0930 Gene

    Size:
    404 amino acids
    Molecular mass:
    45794 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KIAA0930 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0930 Gene

Proteomics data for KIAA0930 Gene at MOPED

Post-translational modifications for KIAA0930 Gene

  • Ubiquitination at Lys 365
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for KIAA0930 Gene

Domains & Families for KIAA0930 Gene

Protein Domains for KIAA0930 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA0930 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0930: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KIAA0930 Gene

Function for KIAA0930 Gene

Molecular function for KIAA0930 Gene

GENATLAS Biochemistry:
related to C elegans cos C16E9

Phenotypes for KIAA0930 Gene

GenomeRNAi human phenotypes for KIAA0930:
genes like me logo Genes that share phenotypes with KIAA0930: view

Animal Model Products

CRISPR Products

miRNA for KIAA0930 Gene

miRTarBase miRNAs that target KIAA0930

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0930 Gene

Localization for KIAA0930 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA0930 Gene COMPARTMENTS Subcellular localization image for KIAA0930 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0930 Gene

Pathways & Interactions for KIAA0930 Gene

SuperPathways for KIAA0930 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA0930 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0930 Gene

Drugs & Compounds for KIAA0930 Gene

No Compound Related Data Available

Transcripts for KIAA0930 Gene

Unigene Clusters for KIAA0930 Gene

KIAA0930:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0930 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c ^ 17a · 17b ^
SP1: - - - - - - - - - -
SP2: - - - - - -
SP3: - - - - - - - - - - - - -
SP4: - - - - - -
SP5: - - - - - - - - - - -
SP6: - - - - - - - -
SP7: - - - - - - - -
SP8: -
SP9: -
SP10: - -
SP11: - - - - - - -
SP12:
SP13:
SP14:

ExUns: 18a · 18b ^ 19a · 19b · 19c
SP1: -
SP2: -
SP3: -
SP4: -
SP5:
SP6:
SP7:
SP8:
SP9: -
SP10: -
SP11:
SP12: -
SP13:
SP14:

Relevant External Links for KIAA0930 Gene

GeneLoc Exon Structure for
KIAA0930
ECgene alternative splicing isoforms for
KIAA0930

Expression for KIAA0930 Gene

mRNA expression in normal human tissues for KIAA0930 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KIAA0930 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (38.9) and Monocytes (19.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA0930 Gene



SOURCE GeneReport for Unigene cluster for KIAA0930 Gene Hs.592207

genes like me logo Genes that share expression patterns with KIAA0930: view

Protein tissue co-expression partners for KIAA0930 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KIAA0930 Gene

Orthologs for KIAA0930 Gene

This gene was present in the common ancestor of animals.

Orthologs for KIAA0930 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0930 35
  • 91.96 (n)
  • 90.3 (a)
cow
(Bos Taurus)
Mammalia KIAA0930 36
  • 97 (a)
OneToOne
KIAA0930 35
  • 91.91 (n)
  • 97.65 (a)
dog
(Canis familiaris)
Mammalia KIAA0930 35
  • 92.08 (n)
  • 97.52 (a)
KIAA0930 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 5031439G07Rik 36
  • 83 (a)
OneToOne
5031439G07Rik 16
5031439G07Rik 35
  • 89.83 (n)
  • 97.27 (a)
oppossum
(Monodelphis domestica)
Mammalia KIAA0930 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0930 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1304694 35
  • 90.65 (n)
  • 97.52 (a)
chicken
(Gallus gallus)
Aves KIAA0930 35
  • 80.18 (n)
  • 91.54 (a)
KIAA0930 36
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA0930 36
  • 81 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC53303 35
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0930 35
  • 80.62 (n)
  • 88.97 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:172139 36
  • 70 (a)
OneToOne
zgc:172139 35
  • 82.05 (n)
  • 88.21 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9646 37
  • 52 (a)
CG9646 36
  • 19 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C16E9.2a 37
  • 37 (a)
C16E9.2 36
  • 33 (a)
OneToOne
Species with no ortholog for KIAA0930:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KIAA0930 Gene

ENSEMBL:
Gene Tree for KIAA0930 (if available)
TreeFam:
Gene Tree for KIAA0930 (if available)

Paralogs for KIAA0930 Gene

(1) SIMAP similar genes for KIAA0930 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with KIAA0930: view

No data available for Paralogs for KIAA0930 Gene

Variants for KIAA0930 Gene

Sequence variations from dbSNP and Humsavar for KIAA0930 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs7456 -- 45,192,367(+) TGTGG(A/G)AGAGG utr-variant-3-prime
rs226520 -- 45,191,865(+) GGTCT(C/T)GAACT downstream-variant-500B
rs133384 -- 45,203,766(+) GCCCC(-/C)ATGGT intron-variant
rs133385 -- 45,204,905(+) CCCGG(-/G)CAGTG intron-variant
rs1515082 -- 45,214,983(+) gaggc(C/T)gtggc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA0930 Gene

Variant ID Type Subtype PubMed ID
nsv834220 CNV Loss 17160897
dgv1411e1 CNV Complex 17122850
nsv9920 CNV Gain 18304495
nsv829278 CNV Loss 20364138
esv1008540 CNV Deletion 20482838
nsv829279 CNV Gain 20364138
esv2724391 CNV Deletion 23290073
esv2724392 CNV Deletion 23290073
esv2677451 CNV Deletion 23128226
esv2925 CNV Deletion 18987735
esv22242 CNV Gain 19812545
dgv787e201 CNV Deletion 23290073
esv5567 CNV Loss 19470904
esv2724394 CNV Deletion 23290073
esv1262903 CNV Deletion 17803354
nsv915294 CNV Loss 21882294

Variation tolerance for KIAA0930 Gene

Residual Variation Intolerance Score: 12.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.75; 15.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA0930 Gene

HapMap Linkage Disequilibrium report
KIAA0930

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0930 Gene

Disorders for KIAA0930 Gene

Relevant External Links for KIAA0930

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA0930

No disorders were found for KIAA0930 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0930 Gene

Publications for KIAA0930 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PMID: 24255178) Couzens A.L. … Gingras A.C. (Sci Signal 2013) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3

Products for KIAA0930 Gene

Sources for KIAA0930 Gene

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