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Aliases for KIAA0907 Gene

Aliases for KIAA0907 Gene

  • KIAA0907 2 3
  • BLOM7 3 4
  • UPF0469 Protein KIAA0907 3
  • SNORA80EHG 3

External Ids for KIAA0907 Gene

Previous GeneCards Identifiers for KIAA0907 Gene

  • GC01M153746
  • GC01M151642
  • GC01M152660
  • GC01M153099
  • GC01M152695
  • GC01M154149
  • GC01M127243

Summaries for KIAA0907 Gene

GeneCards Summary for KIAA0907 Gene

KIAA0907 (KIAA0907) is a Protein Coding gene. GO annotations related to this gene include RNA binding.

Additional gene information for KIAA0907 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0907 Gene

Genomics for KIAA0907 Gene

Regulatory Elements for KIAA0907 Gene

Enhancers for KIAA0907 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H155242 1.5 ENCODE dbSUPER 268.1 +690.2 690200 2.9 FEZF1 YBX1 YY1 ZNF416 ZNF143 ZNF548 SP3 ZFP41 MEF2D ZNF610 KIAA0907 GON4L ENSG00000271267 CLK2 MSTO1 MSTO2P THBS3 RUSC1-AS1 LOC101928120 SHC1
GH01H156656 2.6 VISTA FANTOM5 Ensembl ENCODE dbSUPER 74.2 -729.8 -729817 15.3 MLX ZFP64 DMAP1 ZNF416 ZNF143 SP3 MCM3 ZC3H11A SSRP1 ZNF610 GON4L KIAA0907 LOC246784 RRNAD1 PRCC MSTO2P LMNA ISG20L2 YY1AP1 TSACC
GH01H155222 1.4 ENCODE dbSUPER 117.9 +708.7 708712 5.9 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 KIAA0907 MSTO1 ENSG00000271267 MSTO2P GON4L CLK2 LOC101928120 THBS3 RUSC1-AS1 GBAP1
GH01H154998 1.9 FANTOM5 ENCODE dbSUPER 63.3 +930.0 929991 11.3 MLX YBX1 DMAP1 YY1 ZNF416 ZNF143 SP3 NFYC ZC3H11A PPARGC1A GON4L CLK2 UBAP2L KIAA0907 ENSG00000271267 MSTO1 RUSC1-AS1 THBS3 YY1AP1 FLAD1
GH01H156456 1.8 FANTOM5 ENCODE dbSUPER 66.5 -522.9 -522935 2.7 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 KIAA0907 GON4L ENSG00000271267 LOC246784 RRNAD1 ASH1L LMNA MSTO2P DAP3P1 ENSG00000229961
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around KIAA0907 on UCSC Golden Path with GeneCards custom track

Promoters for KIAA0907 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000014122 242 1601 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1

Genomic Locations for KIAA0907 Gene

Genomic Locations for KIAA0907 Gene
chr1:155,913,043-155,934,442
(GRCh38/hg38)
Size:
21,400 bases
Orientation:
Minus strand
chr1:155,882,834-155,904,191
(GRCh37/hg19)

Genomic View for KIAA0907 Gene

Genes around KIAA0907 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0907 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0907 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0907 Gene

Proteins for KIAA0907 Gene

  • Protein details for KIAA0907 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z7F0-K0907_HUMAN
    Recommended name:
    UPF0469 protein KIAA0907
    Protein Accession:
    Q7Z7F0
    Secondary Accessions:
    • O94981
    • Q7L7Q2
    • Q7Z7E9
    • Q8TBQ0

    Protein attributes for KIAA0907 Gene

    Size:
    614 amino acids
    Molecular mass:
    64845 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA74930.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for KIAA0907 Gene

    Alternative splice isoforms for KIAA0907 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0907 Gene

Post-translational modifications for KIAA0907 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA0907 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA0907 Gene

Domains & Families for KIAA0907 Gene

Gene Families for KIAA0907 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA0907 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA0907 Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z7F0

UniProtKB/Swiss-Prot:

K0907_HUMAN :
  • Belongs to the UPF0469 family.
Family:
  • Belongs to the UPF0469 family.
genes like me logo Genes that share domains with KIAA0907: view

Function for KIAA0907 Gene

Phenotypes From GWAS Catalog for KIAA0907 Gene

Gene Ontology (GO) - Molecular Function for KIAA0907 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IDA 19641227
GO:0005515 protein binding IPI 19641227
genes like me logo Genes that share ontologies with KIAA0907: view
genes like me logo Genes that share phenotypes with KIAA0907: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0907 Gene

Localization for KIAA0907 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA0907 gene
Compartment Confidence
nucleus 5
cytosol 2
plasma membrane 1
mitochondrion 1
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for KIAA0907 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,IBA 19641227
GO:0005681 colocalizes_with spliceosomal complex IDA 19641227
GO:0005737 cytoplasm IDA 19641227
genes like me logo Genes that share ontologies with KIAA0907: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for KIAA0907 Gene

Pathways & Interactions for KIAA0907 Gene

SuperPathways for KIAA0907 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA0907 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006376 mRNA splice site selection IDA 19641227
genes like me logo Genes that share ontologies with KIAA0907: view

No data available for Pathways by source and SIGNOR curated interactions for KIAA0907 Gene

Drugs & Compounds for KIAA0907 Gene

No Compound Related Data Available

Transcripts for KIAA0907 Gene

Unigene Clusters for KIAA0907 Gene

KIAA0907:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0907 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a ·
SP1: - - -
SP2: - - - - - - - -
SP3:
SP4: - -
SP5: - -
SP6: -
SP7: - - - - -
SP8:
SP9:
SP10:
SP11: -

ExUns: 14b · 14c ^ 15 ^ 16
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:

Relevant External Links for KIAA0907 Gene

GeneLoc Exon Structure for
KIAA0907
ECgene alternative splicing isoforms for
KIAA0907

Expression for KIAA0907 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA0907 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KIAA0907 Gene

This gene is overexpressed in Lymph node (32.1) and Fetal gut (12.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA0907 Gene



Protein tissue co-expression partners for KIAA0907 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of KIAA0907 Gene:

KIAA0907

SOURCE GeneReport for Unigene cluster for KIAA0907 Gene:

Hs.24656

Evidence on tissue expression from TISSUES for KIAA0907 Gene

  • Lung(5)
  • Nervous system(4.6)
  • Liver(4.4)
  • Adrenal gland(4.2)
genes like me logo Genes that share expression patterns with KIAA0907: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA0907 Gene

Orthologs for KIAA0907 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0907 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0907 34
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA0907 34
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA0907 33 34
  • 93.69 (n)
dog
(Canis familiaris)
Mammalia KIAA0907 33 34
  • 92.62 (n)
rat
(Rattus norvegicus)
Mammalia RGD1565775 33
  • 90.8 (n)
mouse
(Mus musculus)
Mammalia 2810403A07Rik 33 16 34
  • 90.66 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0907 34
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0907 33 34
  • 80.49 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA0907 34
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0907 33
  • 67.79 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.14194 33
zebrafish
(Danio rerio)
Actinopterygii kiaa0907 33 34
  • 61.04 (n)
Dr.1618 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5853 33
Species where no ortholog for KIAA0907 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0907 Gene

ENSEMBL:
Gene Tree for KIAA0907 (if available)
TreeFam:
Gene Tree for KIAA0907 (if available)

Paralogs for KIAA0907 Gene

No data available for Paralogs for KIAA0907 Gene

Variants for KIAA0907 Gene

Sequence variations from dbSNP and Humsavar for KIAA0907 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000006697 -- 155,932,886(+) GAGCC(A/G)AGATC intron-variant, upstream-variant-2KB
rs1000124773 -- 155,935,244(+) TTGAG(-/AC)AGTTT intron-variant, upstream-variant-2KB
rs1000323098 -- 155,928,816(+) GCGTG(A/G)TGGCA intron-variant
rs1000938679 -- 155,919,923(+) ACCCC(C/T)TTCAG intron-variant, nc-transcript-variant
rs1001187392 -- 155,933,214(+) AAAAC(C/T)AAATG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for KIAA0907 Gene

Variant ID Type Subtype PubMed ID
nsv509513 CNV insertion 20534489
esv33869 CNV loss 17666407

Variation tolerance for KIAA0907 Gene

Residual Variation Intolerance Score: 10.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.79; 16.66% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA0907 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA0907

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0907 Gene

Disorders for KIAA0907 Gene

Relevant External Links for KIAA0907

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA0907

No disorders were found for KIAA0907 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0907 Gene

Publications for KIAA0907 Gene

  1. Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis. (PMID: 21986946) Mei YP … Jiang F (Oncogene 2012) 2 3 60
  2. Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA. (PMID: 23144703) Löscher M … Grillari J (PloS one 2012) 2 3 60
  3. Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4. (PMID: 19641227) Grillari J … Grillari-Voglauer R (The Journal of biological chemistry 2009) 2 3 60
  4. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 3 4 60
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60

Products for KIAA0907 Gene

Sources for KIAA0907 Gene

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