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Aliases for KIAA0895L Gene

Aliases for KIAA0895L Gene

  • KIAA0895 Like 2 3 5

External Ids for KIAA0895L Gene

Previous GeneCards Identifiers for KIAA0895L Gene

  • GC16M065774
  • GC16M065776
  • GC16M067209
  • GC16M053082

Summaries for KIAA0895L Gene

GeneCards Summary for KIAA0895L Gene

KIAA0895L (KIAA0895 Like) is a Protein Coding gene. An important paralog of this gene is KIAA0895.

Gene Wiki entry for KIAA0895L Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0895L Gene

Genomics for KIAA0895L Gene

Regulatory Elements for KIAA0895L Gene

Enhancers for KIAA0895L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G066902 2.3 VISTA FANTOM5 Ensembl ENCODE dbSUPER 21.6 +279.5 279500 4.1 PKNOX1 FOXA2 MLX ARNT ARID4B DMAP1 ZNF2 ZNF48 YY1 SP5 CES2 KIAA0895L E2F4 RRAD FAM96B CENPT EXOC3L1 C16orf70 CES3 LINC00920
GH16G066515 2.1 FANTOM5 Ensembl ENCODE dbSUPER 22.4 +662.8 662817 12.4 CREB3L1 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF416 ZNF548 ZNF263 TK2 CKLF E2F4 KIAA0895L BEAN1 ZDHHC1 CKLF-CMTM1 ENSG00000260465 CMTM2 PLEKHG4
GH16G066378 1.7 FANTOM5 Ensembl ENCODE dbSUPER 23 +802.6 802617 6.4 ATF1 INSM2 YBX1 PLRG1 ZBTB40 RFX5 ZNF155 GATA2 ZNF366 RCOR1 LINC00920 KIAA0895L E2F4 ENSG00000260465 CDH5 GC16P066378
GH16G067520 1.6 Ensembl ENCODE dbSUPER 23.7 -337.4 -337393 1.6 HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZDHHC1 ENSG00000260465 KIAA0895L ACD ENKD1 FBXL8 SLC7A6OS CENPT E2F4 ENSG00000263276
GH16G067555 1.5 Ensembl ENCODE dbSUPER 23.7 -372.3 -372269 2.0 ZNF493 ZFP64 ZNF121 KLF7 FOS ZNF202 REST ZNF623 ZNF518A ZNF292 ZDHHC1 ENSG00000260465 CENPT ACD ENKD1 E2F4 KIAA0895L ENSG00000263276 FBXL8 ENSG00000270165
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around KIAA0895L on UCSC Golden Path with GeneCards custom track

Promoters for KIAA0895L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000087076 40 1201 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 ZNF143

Genomic Location for KIAA0895L Gene

Chromosome:
16
Start:
67,175,602 bp from pter
End:
67,184,040 bp from pter
Size:
8,439 bases
Orientation:
Minus strand

Genomic View for KIAA0895L Gene

Genes around KIAA0895L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0895L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0895L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0895L Gene

Proteins for KIAA0895L Gene

  • Protein details for KIAA0895L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68EN5-K895L_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0895-like
    Protein Accession:
    Q68EN5
    Secondary Accessions:
    • A2VCS8
    • Q8N3H9
    • Q8NAQ5
    • Q96IE5

    Protein attributes for KIAA0895L Gene

    Size:
    471 amino acids
    Molecular mass:
    53446 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI28540.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD38862.1; Type=Erroneous translation; Note=Erroneous translation incorporating non-existent frameshift.; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA0895L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0895L Gene

Post-translational modifications for KIAA0895L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA0895L Gene

No data available for DME Specific Peptides for KIAA0895L Gene

Domains & Families for KIAA0895L Gene

Protein Domains for KIAA0895L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0895L: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA0895L Gene

Function for KIAA0895L Gene

Phenotypes for KIAA0895L Gene

genes like me logo Genes that share phenotypes with KIAA0895L: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0895L Gene

Localization for KIAA0895L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA0895L gene
Compartment Confidence
nucleus 2
cytosol 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0895L Gene

Pathways & Interactions for KIAA0895L Gene

SuperPathways for KIAA0895L Gene

No Data Available

Interacting Proteins for KIAA0895L Gene

Gene Ontology (GO) - Biological Process for KIAA0895L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0895L Gene

Drugs & Compounds for KIAA0895L Gene

No Compound Related Data Available

Transcripts for KIAA0895L Gene

mRNA/cDNA for KIAA0895L Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(12) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KIAA0895L Gene

KIAA0895-like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0895L Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c
SP1: - - - -
SP2: - - -
SP3: -
SP4: - - - - - - - - - -
SP5:
SP6:
SP7: - -
SP8:

Relevant External Links for KIAA0895L Gene

GeneLoc Exon Structure for
KIAA0895L
ECgene alternative splicing isoforms for
KIAA0895L

Expression for KIAA0895L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA0895L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KIAA0895L Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA0895L Gene



Protein tissue co-expression partners for KIAA0895L Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of KIAA0895L Gene:

KIAA0895L

SOURCE GeneReport for Unigene cluster for KIAA0895L Gene:

Hs.651201

Evidence on tissue expression from TISSUES for KIAA0895L Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with KIAA0895L: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA0895L Gene

Orthologs for KIAA0895L Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0895L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0895L 34 35
  • 99.22 (n)
dog
(Canis familiaris)
Mammalia KIAA0895L 35
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA0895L 34 35
  • 89.6 (n)
rat
(Rattus norvegicus)
Mammalia Kiaa0895l 34
  • 83.69 (n)
mouse
(Mus musculus)
Mammalia 4931428F04Rik 34 16 35
  • 83.44 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0895L 35
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA0895L 35
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0895L 34 35
  • 79.31 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA0895L 35
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0895l 34
  • 65.66 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC562097 34
  • 61.86 (n)
BX255936.1 35
  • 51 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 54 (a)
OneToMany
Species where no ortholog for KIAA0895L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0895L Gene

ENSEMBL:
Gene Tree for KIAA0895L (if available)
TreeFam:
Gene Tree for KIAA0895L (if available)

Paralogs for KIAA0895L Gene

Paralogs for KIAA0895L Gene

(1) SIMAP similar genes for KIAA0895L Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for KIAA0895L Gene

genes like me logo Genes that share paralogs with KIAA0895L: view

Variants for KIAA0895L Gene

Sequence variations from dbSNP and Humsavar for KIAA0895L Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000937270 -- 67,175,577(+) ACCTT(-/G)AGTAG intron-variant, utr-variant-3-prime
rs1001482651 -- 67,175,229(+) GCCCA(A/G)GAACT intron-variant, reference, missense, utr-variant-3-prime
rs1001641499 -- 67,175,138(+) CCAAG(A/G)CTCGG intron-variant, reference, missense, utr-variant-3-prime
rs1001789917 -- 67,184,220(+) AACGC(A/C)GTCTG intron-variant, upstream-variant-2KB
rs1003578493 -- 67,183,667(+) GACAA(A/G)GTGAA utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for KIAA0895L Gene

Variant ID Type Subtype PubMed ID
nsv1160429 CNV deletion 26073780
nsv457513 CNV loss 19166990
nsv471092 CNV gain 18288195
nsv522852 CNV gain 19592680
nsv524363 CNV loss 19592680
nsv524492 CNV loss 19592680
nsv572905 CNV loss 21841781
nsv827707 CNV loss 20364138
nsv952044 CNV deletion 24416366

Variation tolerance for KIAA0895L Gene

Residual Variation Intolerance Score: 49.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.32; 70.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA0895L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA0895L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0895L Gene

Disorders for KIAA0895L Gene

Relevant External Links for KIAA0895L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA0895L

No disorders were found for KIAA0895L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0895L Gene

Publications for KIAA0895L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for KIAA0895L Gene

Sources for KIAA0895L Gene

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