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Aliases for KIAA0895 Gene

Aliases for KIAA0895 Gene

  • KIAA0895 2 3

External Ids for KIAA0895 Gene

Previous GeneCards Identifiers for KIAA0895 Gene

  • GC07M036010
  • GC07M036104
  • GC07M036137
  • GC07M036330
  • GC07M036244

Summaries for KIAA0895 Gene

GeneCards Summary for KIAA0895 Gene

KIAA0895 (KIAA0895) is a Protein Coding gene. An important paralog of this gene is KIAA0895L.

Gene Wiki entry for KIAA0895 Gene

Additional gene information for KIAA0895 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0895 Gene

Genomics for KIAA0895 Gene

Regulatory Elements for KIAA0895 Gene

Enhancers for KIAA0895 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H036386 1.6 Ensembl ENCODE dbSUPER 40.5 -1.8 -1756 10 HDGF FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 ZNF143 ZNF207 FOS KIAA0895 HERPUD2 ENSG00000237400
GH07H036366 1 ENCODE 27.5 +23.1 23085 1 ATF1 ARID4B SIN3A BRCA1 YY1 ETS1 GLIS2 ZNF207 ZNF143 ATF7 KIAA0895 ANLN GC07M036337 ENSG00000201432
GH07H036399 0.6 dbSUPER 39.4 -10.3 -10322 2 SREBF1 ZNF121 GATA3 JUND CEBPB ZBTB33 KIAA0895 ENSG00000237400
GH07H036347 0.4 ENCODE 33.8 +42.2 42209 1 PRDM6 KIAA0895 ANLN GC07M036337 ENSG00000201432
GH07H036404 0.7 dbSUPER 13.1 -14.9 -14891 1 HDAC1 IRF2 STAT1 CEBPG ZNF592 FOXA1 ZNF217 MEF2D CTBP1 ZNF766 KIAA0895 ENSG00000237400
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around KIAA0895 on UCSC Golden Path with GeneCards custom track

Promoters for KIAA0895 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000210913 -375 2201 HDGF MLX ARID4B SIN3A DMAP1 ZNF2 ZNF143 ZNF207 FOS DEK

Genomic Location for KIAA0895 Gene

Chromosome:
7
Start:
36,324,150 bp from pter
End:
36,390,125 bp from pter
Size:
65,976 bases
Orientation:
Minus strand

Genomic View for KIAA0895 Gene

Genes around KIAA0895 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0895 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0895 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0895 Gene

Proteins for KIAA0895 Gene

  • Protein details for KIAA0895 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCT3-K0895_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0895
    Protein Accession:
    Q8NCT3
    Secondary Accessions:
    • B4DF35
    • B7ZLT4
    • B9EGB9
    • O94969
    • Q0VGC1
    • Q7Z4L2

    Protein attributes for KIAA0895 Gene

    Size:
    520 amino acids
    Molecular mass:
    60525 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA74918.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA0895 Gene

neXtProt entry for KIAA0895 Gene

Post-translational modifications for KIAA0895 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KIAA0895 Gene

Domains & Families for KIAA0895 Gene

Gene Families for KIAA0895 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA0895 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA0895 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0895: view

No data available for UniProtKB/Swiss-Prot for KIAA0895 Gene

Function for KIAA0895 Gene

genes like me logo Genes that share phenotypes with KIAA0895: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0895 Gene

Localization for KIAA0895 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA0895 gene
Compartment Confidence
nucleus 4
cytosol 3
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cell Junctions (2)
  • Cytosol (2)
  • Nucleus (2)
  • Plasma membrane (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0895 Gene

Pathways & Interactions for KIAA0895 Gene

SuperPathways for KIAA0895 Gene

No Data Available

Interacting Proteins for KIAA0895 Gene

Selected Interacting proteins: Q8NCT3-K0895_HUMAN for KIAA0895 Gene via IID

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for KIAA0895 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0895 Gene

Drugs & Compounds for KIAA0895 Gene

No Compound Related Data Available

Transcripts for KIAA0895 Gene

Unigene Clusters for KIAA0895 Gene

KIAA0895:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0895 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c
SP1: - - - - - - -
SP2: - - -
SP3: - -
SP4: -
SP5: - - -
SP6: - - - -

Relevant External Links for KIAA0895 Gene

GeneLoc Exon Structure for
KIAA0895
ECgene alternative splicing isoforms for
KIAA0895

Expression for KIAA0895 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA0895 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA0895 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.8).

Protein differential expression in normal tissues from HIPED for KIAA0895 Gene

This gene is overexpressed in Plasma (64.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA0895 Gene



Protein tissue co-expression partners for KIAA0895 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of KIAA0895 Gene:

KIAA0895

SOURCE GeneReport for Unigene cluster for KIAA0895 Gene:

Hs.6224

Evidence on tissue expression from TISSUES for KIAA0895 Gene

  • Nervous system(2.7)
genes like me logo Genes that share expression patterns with KIAA0895: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA0895 Gene

Orthologs for KIAA0895 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0895 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0895 33 34
  • 99.87 (n)
dog
(Canis familiaris)
Mammalia KIAA0895 33 34
  • 91.52 (n)
cow
(Bos Taurus)
Mammalia KIAA0895 33 34
  • 90.57 (n)
rat
(Rattus norvegicus)
Mammalia RGD1561444 33
  • 86.72 (n)
mouse
(Mus musculus)
Mammalia 9530077C05Rik 33 16 34
  • 85.43 (n)
oppossum
(Monodelphis domestica)
Mammalia KIAA0895 34
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0895 34
  • 44 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0895 33 34
  • 74.25 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA0895 34
  • 61 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0895 33
  • 67.22 (n)
zebrafish
(Danio rerio)
Actinopterygii si:dkey-222b8.4 33 34
  • 62.96 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 45 (a)
OneToMany
Species where no ortholog for KIAA0895 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0895 Gene

ENSEMBL:
Gene Tree for KIAA0895 (if available)
TreeFam:
Gene Tree for KIAA0895 (if available)

Paralogs for KIAA0895 Gene

Paralogs for KIAA0895 Gene

(1) SIMAP similar genes for KIAA0895 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with KIAA0895: view

Variants for KIAA0895 Gene

Sequence variations from dbSNP and Humsavar for KIAA0895 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000045276 -- 36,352,201(+) CACCA(A/G)CCTGG intron-variant
rs1000120734 -- 36,336,367(+) GCTAT(A/G)TTATT intron-variant
rs1000137945 -- 36,351,859(+) GAGGA(C/T)TGCTT intron-variant
rs1000180882 -- 36,364,195(+) TGATA(C/T)TCCTG intron-variant
rs1000228810 -- 36,378,325(+) CTAAC(A/C)GTCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA0895 Gene

Variant ID Type Subtype PubMed ID
esv275305 CNV loss 21479260
nsv365653 CNV deletion 16902084
nsv365987 CNV deletion 16902084
nsv477480 CNV novel sequence insertion 20440878

Variation tolerance for KIAA0895 Gene

Residual Variation Intolerance Score: 57.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.69; 32.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA0895 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA0895

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0895 Gene

Disorders for KIAA0895 Gene

Relevant External Links for KIAA0895

Genetic Association Database (GAD)
KIAA0895
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA0895

No disorders were found for KIAA0895 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0895 Gene

Publications for KIAA0895 Gene

  1. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 3 4 60
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K … Gorospe M (The EMBO journal 2009) 3 60
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60

Products for KIAA0895 Gene

Sources for KIAA0895 Gene

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