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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIAA0430 Gene

protein-coding   GIFtS: 47
GCID: GC16M015596

KIAA0430

  Search for KIAA0430
in our new
 Human Malady Compendium 
Biological research products
for KIAA0430
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
KIAA04301 2     Limkain-B11
LKAP1 2 3     Meiosis Arrest Female 12
PPP1R341 2     Meiosis Arrest Female Protein 12
MARF12 3     Protein Phosphatase 1, Regulatory Subunit 342
Marf11     Limkain-B11
Limkain B12     

External Ids:    HGNC: 295621   Entrez Gene: 96652   Ensembl: ENSG000001667837   OMIM: 6145935   UniProtKB: Q9Y4F33   

Export aliases for KIAA0430 gene to outside databases

Previous GC identifer: GC16M015083


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KIAA0430:
This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be
autoantigenic. (provided by RefSeq, Jul 2010)

UniProtKB/Swiss-Prot: MARF1_HUMAN, Q9Y4F3
Function: Essential regulator of oogenesis required for female meiotic progression. Acts by down-regulating RNA
transcripts, either at transcriptional of post-transcriptional level (By similarity)

Gene Wiki entry for KIAA0430


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIAA0430 gene promoter:
         Elk-1   ISGF-3   p300   Lmo2   NF-kappaB   C/EBPalpha   AREB6   NF-kappaB1   TGIF   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKIAA0430 promoter sequence
   Search SABiosciences Chromatin IP Primers for KIAA0430

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0430


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.11   Ensembl cytogenetic band:  16p13.11   HGNC cytogenetic band: 16p13.11

KIAA0430 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIAA0430 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M015596:  view genomic region     (about GC identifiers)

Start:
15,688,226 bp from pter      End:
15,737,023 bp from pter
Size:
48,798 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MARF1_HUMAN, Q9Y4F3 (See protein sequence)
Recommended Name: Meiosis arrest female protein 1  
Size: 1742 amino acids; 192859 Da
Subunit: Interacts with LIMK2
Subcellular location: Peroxisome
Sequence caution: Sequence=AAC31662.1; Type=Erroneous gene model prediction; Sequence=AAH64914.2; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=EAW53920.1; Type=Erroneous gene model
prediction;
2 PDB 3D structures from and Proteopedia for KIAA0430:
2DGX (3D)        2DIU (3D)    
Secondary accessions: A8MSK2 B2RNX2 B4DYY9 B7ZMG1 B7ZMG2 F8VV09 Q6P1R6 Q8WYR2 Q9Y4J9
Alternative splicing: 5 isoforms:  Q9Y4F3-1   Q9Y4F3-3   Q9Y4F3-4   Q9Y4F3-5   Q9Y4F3-6   (May be due to an intron retention)

Explore the universe of human proteins at neXtProt for KIAA0430: NX_Q9Y4F3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y4F3

  • KIAA0430 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001171927.1  NP_001171928.1  NP_055462.2  

    ENSEMBL proteins: 
     ENSP00000379654   ENSP00000439819   ENSP00000449376   ENSP00000450309   ENSP00000449050  
     ENSP00000449329   ENSP00000448495   ENSP00000341939  

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    Uscn Proteins for KIAA0430

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome IDA15932519


    KIAA0430 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    KIAA0430 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR024768 Limkain-b1
     IPR021139 NYN_limkain-b1
     IPR012677 Nucleotide-bd_a/b_plait
     IPR025605 OST-HTH/LOTUS_dom
     IPR024582 Limkain_b1_cons_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y4F3

    ProtoNet protein and cluster: Q9Y4F3

    UniProtKB/Swiss-Prot: MARF1_HUMAN, Q9Y4F3
    Similarity: Contains 8 HTH OST-type domains
    Similarity: Contains 1 NYN domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MARF1_HUMAN, Q9Y4F3
    Function: Essential regulator of oogenesis required for female meiotic progression. Acts by down-regulating RNA
    transcripts, either at transcriptional of post-transcriptional level (By similarity)

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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003674molecular_function ND--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--


    KIAA0430 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for KIAA0430:
     Increased S DNA content  Increased number of mitotic ce 

    Animal Models:
         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Marf1):
     reproductive system 

    KIAA0430 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA0430

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for KIAA0430 (Q9Y4F33 ENSP000003796544) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    GRB2P629933I2D: score=2 
    PPP1CAENSP000003260314STRING: ENSP00000326031
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007143female meiosis ISS--
    GO:0010468regulation of gene expression ISS--
    GO:0010923negative regulation of phosphatase activity IDA19389623
    GO:0030154cell differentiation IEA--
    GO:0048477oogenesis ISS--


    KIAA0430 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for KIAA0430
    Search CenterWatch for drugs/clinical trials and news about KIAA0430 / MARF1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KIAA0430 gene (4 alternative transcripts): 
    NM_019081.2  NM_001184998.1  NM_001184999.1  NM_014647.3  

    Unigene Cluster for KIAA0430:

    KIAA0430
    Hs.173524  [show with all ESTs]
    Unigene Representative Sequence: NM_014647
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396368(uc002ddq.3 uc002ddr.3 uc010uzv.2 uc010uzw.2)
    ENST00000540441 ENST00000552771 ENST00000548025 ENST00000551742 ENST00000551878
    ENST00000552553 ENST00000551579 ENST00000549337 ENST00000547936 ENST00000552535
    ENST00000546864 ENST00000551678 ENST00000548216(uc010uzx.2) ENST00000549219
    ENST00000344181

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    Additional cDNA sequence: 

    AB007890.3 AB012134.1 AK095840.1 AK302667.1 BC041135.1 BC064914.1 BC127740.1 BC137165.1 
    BC137170.1 BC139919.1 BC141831.1 BC144514.1 BC144515.1 

    18 DOTS entries:

    DT.100789349  DT.91650930  DT.99996282  DT.102841925  DT.91660434  DT.120692811  DT.100789347  DT.99958185 
    DT.115700  DT.91646734  DT.100849154  DT.120691899  DT.40288072  DT.100789350  DT.120691946  DT.120692782 
    DT.101984703  DT.91730123 

    24/234 AceView cDNA sequences (see all 234):

    AU140821 AA865755 BU607280 AA283075 AA832491 BE763124 AB012134 AA806058 
    AI695046 BM771620 AA810228 AI434727 AU121452 AB007890 CB137928 BM824633 
    BQ434932 BX093887 BC041135 NM_014647 AA134255 BQ029920 AI610832 CB215949 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0430 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18 ^
    SP1:                                                                                                                                -                           
    SP2:                                                                                                                                                            
    SP3:                                                        -                                                                                                   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25a · 25b · 25c ^ 26 ^ 27a · 27b · 27c ^ 28a · 28b
    SP1:                    -                       -     -                 -                           
    SP2:                                                                                                
    SP3:                                                                                                
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for KIAA0430

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIAA0430 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAAAGAGTGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See KIAA0430 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIAA0430

    SOURCE GeneReport for Unigene cluster: Hs.173524
        SABiosciences Custom PCR Arrays for KIAA0430
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KIAA0430 gene from 6/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Marf11 , 5 RIKEN cDNA 4921513D23 gene5
    meiosis arrest female 11
    85.25(n)1
    86.52(a)1
      16 (9.69 cM)5
    2239891  NM_001081154.21  NP_001074623.11 
     141091665 
    chicken
    (Gallus gallus)
    Aves MARF11 KIAA0430 76.43(n)
    79.5(a)
      416595  XM_414895.3  XP_414895.3 
    lizard
    (Anolis carolinensis)
    Reptilia KIAA04306
    KIAA04306
    --
    75(a)
    45(a)
    many → 1
    many → 1
    AAWZ02038395(964-11763)
    GL343580.1(164099-208701)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.49302 Xenopus laevis transcribed sequence with weak similarity more 75.41(n)    BG513834.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.103642 Transcribed sequence with weak similarity to protein more 72.26(n)    CK140063.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG170186
    --
    20(a)
    1 ↔ 1
    2L(22311931-22368796)


    ENSEMBL Gene Tree for KIAA0430 (if available)
    TreeFam Gene Tree for KIAA0430 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/869 NCBI SNPs in KIAA0430 are shown (see all 869    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs127087991,2
    C,F,A,H,--15081758(+) AAAGCA/TTGCTT 3 -- ds500120Minor allele frequency- T:0.19NS EA NA WA 2292
    rs454520991,2
    C,--15082357(+) ATCCGG/ATATAT 3 -- ut311Minor allele frequency- A:0.50NA 2
    rs283624801,2
    F,--15082658(-) CTCAAA/GGAACA 3 -- ut31 ese32Minor allele frequency- G:0.03MN EA 1252
    rs802790351,2
    F,--15082907(+) GATTCG/AGAGAG 3 -- ut311Minor allele frequency- A:0.06WA 118
    rs38035771,2
    C,H--15082994(-) TAAATG/TAAGCC 3 -- ut317Minor allele frequency- T:0.00NS EA NA 594
    rs570665581,2
    --15083732(+) AACTGC/GAACAC 3 -- ut310--------
    rs1156840231,2
    C,F,--15083929(+) CACTCC/TGAACC 3 -- ut311Minor allele frequency- T:0.03WA 118
    rs1161329841,2
    C,F,--15084024(+) AATACT/CGTCGG 3 -- ut311Minor allele frequency- C:0.03WA 118
    rs285930341,2
    C,--15085090(+) AGGGGG/ATGGGG 3 -- int13Minor allele frequency- A:0.18WA NA 240
    rs118600111,2
    C,F,H,--15085462(+) AAGAGC/TGGCTG 3 -- int111Minor allele frequency- T:0.03NS EA NA WA 1030

    HapMap Linkage Disequilibrium report for KIAA0430 (15688226 - 15737023 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for KIAA0430
         1 CNV: 2203
         1 Indel: 58750

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    KIAA0430 for disorders           About MalaCards

    KIAA0430 for disorders           About GeneDecksing

    OMIM gene information: 614593    OMIM disorders: --


    Export disorders for KIAA0430 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIAA0430 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with KIAA0430)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. (PubMed id 15932519)1, 2, 3, 9 Dunster K.... Sentry J.W. (2005)
    2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 2, 3 Loftus B.J.... Adams M.D. (1999)
    3. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2, 3 Ishikawa K....Ohara O. (1997)
    4. Meiosis arrest female 1 (MARF1) has nuage-like functio n in mammalian oocytes. (PubMed id 23090997)1, 3 Su Y.Q....Eppig J.J. (2012)
    5. MARF1 regulates essential oogenic processes in mice. (PubMed id 22442484)1, 3 Su Y.Q....Eppig J.J. (2012)
    6. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9665 HGNC: 29562 AceView: LKAP Ensembl:ENSG00000166783 euGenes: HUgn9665
    ECgene: KIAA0430 H-InvDB: KIAA0430

    (According to HUGE)
    About This Section
    HUGE: KIAA0430

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIAA0430 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KIAA0430 gene:
    Search GeneIP for patents involving KIAA0430

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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