Aliases for KIAA0430 Gene
External Ids for KIAA0430 Gene
Previous GeneCards Identifiers for KIAA0430 Gene
This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic. [provided by RefSeq, Jul 2010]
GeneCards Summary for KIAA0430 Gene
KIAA0430 (KIAA0430) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding.
UniProtKB/Swiss-Prot for KIAA0430 Gene
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).