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Aliases for KIAA0408 Gene

Aliases for KIAA0408 Gene

  • KIAA0408 2 3

External Ids for KIAA0408 Gene

Previous GeneCards Identifiers for KIAA0408 Gene

  • GC06M127608
  • GC06M127742
  • GC06M127745
  • GC06M127803
  • GC06M127761

Summaries for KIAA0408 Gene

GeneCards Summary for KIAA0408 Gene

KIAA0408 (KIAA0408) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0408 Gene

Genomics for KIAA0408 Gene

Regulatory Elements for KIAA0408 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KIAA0408 Gene

Chromosome:
6
Start:
127,438,406 bp from pter
End:
127,459,391 bp from pter
Size:
20,986 bases
Orientation:
Minus strand

Genomic View for KIAA0408 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for KIAA0408 Gene

Proteins for KIAA0408 Gene

  • Protein details for KIAA0408 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZU52-K0408_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0408
    Protein Accession:
    Q6ZU52
    Secondary Accessions:
    • B3KRE5
    • E1P573
    • O43158
    • Q5TF20
    • Q7L2M2

    Protein attributes for KIAA0408 Gene

    Size:
    694 amino acids
    Molecular mass:
    79163 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA23704.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA0408 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0408 Gene

Proteomics data for KIAA0408 Gene at MOPED

Post-translational modifications for KIAA0408 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA0408 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA0408 Gene

Domains & Families for KIAA0408 Gene

Protein Domains for KIAA0408 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0408: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA0408 Gene

Function for KIAA0408 Gene

Gene Ontology (GO) - Molecular Function for KIAA0408 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with KIAA0408: view

Phenotypes for KIAA0408 Gene

GenomeRNAi human phenotypes for KIAA0408:
genes like me logo Genes that share phenotypes with KIAA0408: view

Animal Model Products

CRISPR Products

miRNA for KIAA0408 Gene

miRTarBase miRNAs that target KIAA0408

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KIAA0408

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0408 Gene

Localization for KIAA0408 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for KIAA0408 Gene

Pathways & Interactions for KIAA0408 Gene

SuperPathways for KIAA0408 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA0408 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0408 Gene

Drugs & Compounds for KIAA0408 Gene

No Compound Related Data Available

Transcripts for KIAA0408 Gene

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KIAA0408

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0408 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c · 11d ^ 12 ^ 13a · 13b · 13c · 13d ^
SP1: - - - -
SP2: - - - -
SP3: -
SP4: - - - -
SP5: - -
SP6: -
SP7: -
SP8: -
SP9: -
SP10:
SP11:

ExUns: 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: -
SP11:

Relevant External Links for KIAA0408 Gene

GeneLoc Exon Structure for
KIAA0408
ECgene alternative splicing isoforms for
KIAA0408

Expression for KIAA0408 Gene

mRNA expression in normal human tissues for KIAA0408 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA0408 Gene

This gene is overexpressed in Muscle - Skeletal (x9.4), Esophagus - Muscularis (x5.2), and Esophagus - Gastroesophageal Junction (x4.8).

Protein differential expression in normal tissues from HIPED for KIAA0408 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (61.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KIAA0408 Gene



genes like me logo Genes that share expression patterns with KIAA0408: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for KIAA0408 Gene

Orthologs for KIAA0408 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0408 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia KIAA0408 35
  • 83.2 (n)
  • 71.47 (a)
KIAA0408 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 9330159F19Rik 35
  • 76.46 (n)
  • 60.51 (a)
Soga3 16
9330159F19Rik 36
  • 59 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SOGA3 35
  • 99.38 (n)
  • 98.99 (a)
KIAA0408 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rgd1310049 35
  • 74.78 (n)
  • 62.1 (a)
dog
(Canis familiaris)
Mammalia KIAA0408 36
  • 71 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA0408 36
  • 45 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0408 36
  • 37 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0408 35
  • 59.97 (n)
  • 45.41 (a)
KIAA0408 36
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA0408 36
  • 38 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii soga3a 35
  • 45.05 (n)
  • 33.99 (a)
soga3a 36
  • 20 (a)
OneToMany
soga3a 36
  • 19 (a)
OneToMany
Species with no ortholog for KIAA0408:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0408 Gene

ENSEMBL:
Gene Tree for KIAA0408 (if available)
TreeFam:
Gene Tree for KIAA0408 (if available)

Paralogs for KIAA0408 Gene

(3) SIMAP similar genes for KIAA0408 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with KIAA0408: view

No data available for Paralogs for KIAA0408 Gene

Variants for KIAA0408 Gene

Sequence variations from dbSNP and Humsavar for KIAA0408 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
VAR_027082 -
VAR_049510 -

Variation tolerance for KIAA0408 Gene

Residual Variation Intolerance Score: 27.43% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.87; 83.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA0408 Gene

HapMap Linkage Disequilibrium report
KIAA0408

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for KIAA0408 Gene

Disorders for KIAA0408 Gene

Relevant External Links for KIAA0408

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA0408
genes like me logo Genes that share disorders with KIAA0408: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0408 Gene

Publications for KIAA0408 Gene

  1. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 67
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 67
  5. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 67

Products for KIAA0408 Gene

Sources for KIAA0408 Gene

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