Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



KIAA0368 Gene

protein-coding   GIFtS: 52
GCID: GC09M114122

KIAA0368

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
KIAA03681 2     Homolog Of Yeast Ecm292
ECM29 Homolog (S. Cerevisiae)1     Proteasome-Associated Protein ECM29 Homolog2
ECM292     Ecm293
ECM29 Homolog, Proteasome Accessory Protein2     

External Ids:    HGNC: 290201   Entrez Gene: 233922   Ensembl: ENSG000001368137   UniProtKB: Q5VYK33   

Export aliases for KIAA0368 gene to outside databases

Previous GC identifers: GC09M104921 GC09M105855 GC09M107580 GC09M109502 GC09M109504 GC09M111203 GC09M113162 GC09M083721


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for KIAA0368 Gene:
KIAA0368 (KIAA0368) is a protein-coding gene.

UniProtKB/Swiss-Prot: ECM29_HUMAN, Q5VYK3
Function: Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment
specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum
and centrosome. May play a role in ERAD and other enhanced proteolyis

Gene Wiki entry for KIAA0368 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KIAA0368 gene promoter:
         c-Fos   TBP   AP-1   E4BP4   Evi-1   Max   Meis-1a   c-Jun   Meis-1   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for KIAA0368

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIAA0368


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q31.3   Ensembl cytogenetic band:  9q31.3   HGNC cytogenetic band: 9q32

KIAA0368 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIAA0368 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M114122:  view genomic region     (about GC identifiers)

Start:
114,122,972 bp from pter      End:
114,247,025 bp from pter
Size:
124,054 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ECM29_HUMAN, Q5VYK3 (See protein sequence)
Recommended Name: Proteasome-associated protein ECM29 homolog  
Size: 1845 amino acids; 204291 Da
Subunit: Non-stoichiometric component of the proteasome; associates with the 26S proteasome. Interacts (via
N-terminus) with VPS11, VPS26A, VPS36, RAB11FIP4 and RABEP1. Interacts (via C-terminus) with DCTN1, DCTN2, KIF5B,
MYH7, MYH10, MYO10 and ARF6
Sequence caution: Sequence=AAH21127.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAH73240.1; Type=Erroneous gene model prediction; Sequence=CAH73465.1; Type=Erroneous gene model
prediction;
Secondary accessions: O15074 Q8WU82

Explore the universe of human proteins at neXtProt for KIAA0368: NX_Q5VYK3

Explore proteomics data for KIAA0368 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KIAA0368 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001073867.1  
    ENSEMBL proteins: 
     ENSP00000339889   ENSP00000363504   ENSP00000473399   ENSP00000473402   ENSP00000259335  
     ENSP00000363499  

    KIAA0368 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for KIAA0368
    GenScript Custom Purified and Recombinant Proteins Services for KIAA0368
    Novus Biologicals KIAA0368 Protein
    Novus Biologicals KIAA0368 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for KIAA0368 

     
    antibodies-online proteins for KIAA0368 (3 products) 

     
    Search antibodies-online for peptides for KIAA0368

    KIAA0368 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for KIAA0368
    Novus Biologicals KIAA0368 Antibodies
    Abcam antibodies for KIAA0368
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for KIAA0368
    antibodies-online antibodies for KIAA0368 (7 products) 

    KIAA0368 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KIAA0368
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KIAA0368
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for KIAA0368 
    antibodies-online kits for KIAA0368 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    5 InterPro protein domains:
     IPR011989 ARM-like
     IPR026827 ECM29/GCN1
     IPR026826 ECM29_metazoa
     IPR024372 Proteasome_stabil_ECM29
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q5VYK3

    ProtoNet protein and cluster: Q5VYK3

    UniProtKB/Swiss-Prot: ECM29_HUMAN, Q5VYK3
    Similarity: Contains 27 HEAT repeats


    Find genes that share domains with KIAA0368           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ECM29_HUMAN, Q5VYK3
    Function: Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment
    specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum
    and centrosome. May play a role in ERAD and other enhanced proteolyis

         Genatlas biochemistry entry for KIAA0368:
    cDNA sequence,expressed in brain,>100kDa,related to C elegans cosmid D2045

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005488binding ----
         
    Find genes that share ontologies with KIAA0368           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for KIAA0368:
     Increased G1 DNA content  Increased cell size 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KIAA0368

    miRNA
    Products:
        
    miRTarBase miRNAs that target KIAA0368:
    hsa-mir-320a (MIRT044767), hsa-mir-185-5p (MIRT045343), hsa-mir-16-5p (MIRT031553), hsa-mir-26b-5p (MIRT029119), hsa-mir-155-5p (MIRT020594)

    Block miRNA regulation of human, mouse, rat KIAA0368 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIAA0368 (see all 19):
    hsa-miR-320a hsa-miR-4263 hsa-miR-548v hsa-miR-221 hsa-miR-205* hsa-miR-450b-5p hsa-miR-187* hsa-miR-183
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KIAA0368
    Predesigned siRNA for gene silencing in human, mouse, rat KIAA0368

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KIAA0368

    Clone
    Products:
         
    OriGene clones in human, mouse for KIAA0368 (see all 5)
    OriGene ORF clones in mouse, rat for KIAA0368
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KIAA0368 (NM_001080398)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIAA0368
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0368

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KIAA0368
    Browse ESI BIO Cell Lines and PureStem Progenitors for KIAA0368 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0368


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ECM29_HUMAN, Q5VYK3: Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment. Endosome.
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Endosome, multivesicular body.
    Cytoplasmic vesicle
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    endoplasmic reticulum5
    endosome5
    nucleus5
    cytosol1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000502colocalizes with proteasome complex IDA15496406
    GO:0005634nucleus IDA15496406
    GO:0005769early endosome IDA15496406
    GO:0005770late endosome IDA15496406
    GO:0005771multivesicular body IDA--

    Find genes that share ontologies with KIAA0368           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIAA0368
    Interactions:

        Search GeneGlobe Interaction Network for KIAA0368

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for KIAA0368 (Q5VYK32, 3 ENSP000002593354) via UniProtKB, MINT, STRING, and/or I2D (see all 603)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTPS1P178122, 3MINT-8173832 I2D: score=2 
    IKBKGQ9Y6K92, 3MINT-48195 I2D: score=2 
    AGPAT1Q999433, ENSP000003374634I2D: score=3 STRING: ENSP00000337463
    ENSG00000206324Q999433, ENSP000003827234I2D: score=3 STRING: ENSP00000382723
    ENSG00000226467Q999433, ENSP000004058644I2D: score=3 STRING: ENSP00000405864
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030433ER-associated ubiquitin-dependent protein catabolic process IMP15496406

    Find genes that share ontologies with KIAA0368           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KIAA0368 (ECM29)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for KIAA0368 gene: 
    NM_001080398.1  

    Unigene Cluster for KIAA0368:

    KIAA0368
    Hs.368255  [show with all ESTs]
    Unigene Representative Sequence: NM_001080398
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000338205(uc010muc.1) ENST00000374383 ENST00000465499 ENST00000602447
    ENST00000602978 ENST00000259335(uc004bfe.1) ENST00000374378
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KIAA0368 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIAA0368 (see all 19):
    hsa-miR-320a hsa-miR-4263 hsa-miR-548v hsa-miR-221 hsa-miR-205* hsa-miR-450b-5p hsa-miR-187* hsa-miR-183
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KIAA0368
    Predesigned siRNA for gene silencing in human, mouse, rat KIAA0368
    Clone
    Products:
         
    OriGene clones in human, mouse for KIAA0368 (see all 5)
    OriGene ORF clones in mouse, rat for KIAA0368
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KIAA0368 (NM_001080398)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIAA0368
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0368
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KIAA0368
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KIAA0368
      QuantiTect SYBR Green Assays in human, mouse, rat KIAA0368
      QuantiFast Probe-based Assays in human, mouse, rat KIAA0368

    Additional mRNA sequence: 

    AB002366.1 AF052139.1 AK024705.1 AK025689.1 AK027063.1 AK122712.1 AK124590.1 AK127247.1 
    AK308313.1 BC021127.1 

    19 DOTS entries:

    DT.117279  DT.97847982  DT.434076  DT.121158767  DT.97780216  DT.121158786  DT.75131147  DT.100665929 
    DT.121158775  DT.121158783  DT.95183944  DT.97777994  DT.100675564  DT.100792160  DT.121158749  DT.91757306 
    DT.92029372  DT.75118687  DT.91654203 

    Selected AceView cDNA sequences (see all 267):

    BQ776532 AW512399 AU125982 BE868091 AA453842 BQ215159 BM856243 AU125447 
    C00385 BM771558 T09487 BQ437531 BG679286 CA391541 AA313215 BU182219 
    BM766172 AA029232 BM784152 AA683594 AL040866 CB529882 AI955188 BM764473 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    KIAA0368 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    KIAA0368 Expression
    About this image


    KIAA0368 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Limb (Muscoskeletal System)
             Limb Bud
     
     Thyroid (Endocrine System)
     
     Testis (Reproductive System)
    KIAA0368 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIAA0368 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.368255
        Custom PCR Arrays for KIAA0368
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for KIAA0368
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KIAA0368
    QuantiTect SYBR Green Assays in human, mouse, rat KIAA0368
    QuantiFast Probe-based Assays in human, mouse, rat KIAA0368
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0368

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KIAA0368 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia AI3141801 , 5 expressed sequence AI3141801, 5 89.91(n)1
    95.58(a)1
      4 (32.35 cM)5
    2302491  NM_172381.21  NP_759013.21 
     587989115 
    chicken
    (Gallus gallus)
    Aves KIAA03681 KIAA0368 78.27(n)
    85.74(a)
      427336  XM_424915.4  XP_424915.2 
    lizard
    (Anolis carolinensis)
    Reptilia KIAA03686
    KIAA0368
    85(a)
    1 ↔ 1
    GL343476.1(403949-464679)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.279122 Xenopus laevis transcribed sequence with weak similarity more 75.91(n)    BU912362.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5637771 Proteasome-associated protein ECM29 homolog-like 68.5(n)
    74.88(a)
      563777  NM_001162486.1  NP_001155958.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG88581 , 3 CG88581 30(a)3
    46.26(n)1
    35.72(a)1
      48E83
    363191  NM_136902.21  NP_610746.11 
    worm
    (Caenorhabditis elegans)
    Secernentea D2045.23   -- 33(a)   III(10524551-10532102)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ECM29(YHL030W)4 Scaffold protein that assists in association of the more   --   8(40084-45690) 856355  NP_011833.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G267801 AT2G26780 44.36(n)
    32.16(a)
      817219  NM_179755.3  NP_850086.2 
    rice
    (Oryza sativa)
    Liliopsida Os11g01373001 Os11g0137300 45.64(n)
    31.15(a)
      4349719  NM_001072228.1  NP_001065696.1 


    ENSEMBL Gene Tree for KIAA0368 (if available)
    TreeFam Gene Tree for KIAA0368 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for KIAA0368 gene
    1 SIMAP similar gene for KIAA0368 using alignment to 5 protein entries:     F6XAQ5_HUMAN (see all proteins):
    ECM29

    Find genes that share paralogs with KIAA0368           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for KIAA0368
    PGOHUM00000250507


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for KIAA0368 (see all 2447)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs599370561,2
    C--83827930(+) CACAC-/AC    
       
    /ACAC
    GTTTT
    1 -- int11NA 2
    rs1503605811,2
    --114122492(+) GAGTAC/TTTGGT 1 -- ds50010--------
    rs1910405471,2
    --114122542(+) AAGACA/GCCATA 1 -- ds50010--------
    rs1380784691,2
    --114122561(+) AAAAAA/CCATCC 1 -- ds50010--------
    rs1837988041,2
    --114122565(+) AACATC/TCGAAG 1 -- ds50010--------
    rs123395251,2
    H--114122592(+) CAATAG/ACCATT 1 -- ds50014Minor allele frequency- A:0.00NS EA 420
    rs1882856201,2
    C--114122593(+) AATAGC/TCATTC 1 -- ds50010--------
    rs1932950481,2
    --114122653(+) ACTGAC/TGTTCA 1 -- ds50010--------
    rs777054281,2
    C,F--114122696(+) ACTTAA/TATTTT 1 -- ds50011Minor allele frequency- T:0.12WA 118
    rs169159921,2
    C,F,H--114122763(+) TAGGTG/ACTATC 1 -- ds500122Minor allele frequency- A:0.03NA NS EA 2218

    HapMap Linkage Disequilibrium report for KIAA0368 (114122972 - 114247025 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for KIAA0368 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2666027CNV Deletion23128226
    esv2057050CNV Deletion18987734
    esv2659400CNV Deletion23128226
    esv2738934CNV Deletion23290073
    esv2492334CNV Deletion19546169
    esv2738935CNV Deletion23290073
    nsv436620CNV Deletion17901297
    nsv416941CNV Loss16902084
    nsv525736CNV Loss19592680
    esv29361CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KIAA0368
    DNA2.0 Custom Variant and Variant Library Synthesis for KIAA0368

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease from the University of Copenhagen DISEASES database for KIAA0368:
    Allergic contact dermatitis

    Find genes that share disorders with KIAA0368           About GenesLikeMe

    Genetic Association Database (GAD): KIAA0368
    Human Genome Epidemiology (HuGE) Navigator: KIAA0368 (1 document)

    Export disorders for KIAA0368 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for KIAA0368 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with KIAA0368)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. (PubMed id 20682791)1, 2, 3 Gorbea C.... Rechsteiner M. (J. Biol. Chem. 2010)
    2. Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles. (PubMed id 15496406)1, 2, 3 Gorbea C.... Rechsteiner M. (J. Biol. Chem. 2004)
    3. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1997)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)
    9. Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach. (PubMed id 23464991)1 Scifo E....Lalowski M. (J. Proteome Res. 2013)
    10. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 23392 HGNC: 29020 AceView: KIAA0368 Ensembl:ENSG00000136813 euGenes: HUgn23392
    ECgene: KIAA0368 H-InvDB: KIAA0368

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0368

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for KIAA0368 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for KIAA0368 gene:
    Search GeneIP for patents involving KIAA0368

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KIAA0368  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for KIAA0368  
     OriGene qSTAR qPCR primer pairs in human, mouse for KIAA0368   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for KIAA0368   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KIAA0368   OriGene Custom Protein Services for KIAA0368  

     
     
     Block miRNA regulation of human, mouse, rat KIAA0368 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing KIAA0368
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIAA0368 Predesigned siRNA for gene silencing in human, mouse, rat KIAA0368
     QuantiFast Probe-based Assays in human, mouse, rat KIAA0368 QuantiTect SYBR Green Assays in human, mouse, rat KIAA0368
     Custom PCR Arrays for KIAA0368 Search Chromatin IP Primers for KIAA0368
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KIAA0368  Search GeneGlobe Interaction Network for KIAA0368
     Regulatory tfbs in KIAA0368 promoter
     GenScript Custom Purified and Recombinant Proteins Services for KIAA0368 GenScript cDNA clones with any tag delivered in your preferred vector for KIAA0368
     GenScript Custom Assay Services for KIAA0368 GenScript Custom overexpressing Cell Line Services for KIAA0368
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for KIAA0368 (ECM29)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     KIAA0368 antibodies
     KIAA0368 proteins
     KIAA0368 lysates
     Antibodies for KIAA0368
     See all of Abcam's Antibodies, Kits and Proteins for KIAA0368
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for KIAA0368
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0368
     Browse SwitchGear 3'UTR luciferase reporter plasmids for KIAA0368
     Browse SwitchGear Promoter luciferase reporter plasmids for KIAA0368
     ThermoFisher Antibody for KIAA0368
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0368
     Browse compounds at ApexBio
     Search Addgene for plasmids for KIAA0368
      Search eBioscience for proteins for KIAA0368
      Search eBioscience for elisas for KIAA0368
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for KIAA0368
     antibodies-online antibodies for KIAA0368 (7 products)
     antibodies-online kits for KIAA0368 (2 products)
      Search antibodies-online for peptides for KIAA0368
     antibodies-online proteins for KIAA0368 (3 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KIAA0368 gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4