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Aliases for KIAA0355 Gene

Aliases for KIAA0355 Gene

  • KIAA0355 2 3

External Ids for KIAA0355 Gene

Previous GeneCards Identifiers for KIAA0355 Gene

  • GC19P035363
  • GC19P035194
  • GC19P039421
  • GC19P039437
  • GC19P039482
  • GC19P034745
  • GC19P031250

Summaries for KIAA0355 Gene

GeneCards Summary for KIAA0355 Gene

KIAA0355 (KIAA0355) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0355 Gene

Genomics for KIAA0355 Gene

Regulatory Elements for KIAA0355 Gene

Enhancers for KIAA0355 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around KIAA0355 on UCSC Golden Path with GeneCards custom track

Promoters for KIAA0355 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around KIAA0355 on UCSC Golden Path with GeneCards custom track

Genomic Location for KIAA0355 Gene

Chromosome:
19
Start:
34,254,537 bp from pter
End:
34,355,586 bp from pter
Size:
101,050 bases
Orientation:
Plus strand

Genomic View for KIAA0355 Gene

Genes around KIAA0355 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0355 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0355 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0355 Gene

Proteins for KIAA0355 Gene

  • Protein details for KIAA0355 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15063-K0355_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0355
    Protein Accession:
    O15063
    Secondary Accessions:
    • Q2M3W4

    Protein attributes for KIAA0355 Gene

    Size:
    1070 amino acids
    Molecular mass:
    116020 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA20812.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for KIAA0355 Gene

Proteomics data for KIAA0355 Gene at MOPED

Post-translational modifications for KIAA0355 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA0355 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA0355 Gene

Domains & Families for KIAA0355 Gene

Protein Domains for KIAA0355 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA0355 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0355: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KIAA0355 Gene

Function for KIAA0355 Gene

Molecular function for KIAA0355 Gene

GENATLAS Biochemistry:
cDNA sequence,expressed in brain,>100kDa

Phenotypes for KIAA0355 Gene

GenomeRNAi human phenotypes for KIAA0355:
genes like me logo Genes that share phenotypes with KIAA0355: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0355 Gene

Localization for KIAA0355 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA0355 Gene COMPARTMENTS Subcellular localization image for KIAA0355 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0355 Gene

Pathways & Interactions for KIAA0355 Gene

SuperPathways for KIAA0355 Gene

No Data Available

Interacting Proteins for KIAA0355 Gene

Gene Ontology (GO) - Biological Process for KIAA0355 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0355 Gene

Drugs & Compounds for KIAA0355 Gene

No Compound Related Data Available

Transcripts for KIAA0355 Gene

Unigene Clusters for KIAA0355 Gene

KIAA0355:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0355 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
SP1:
SP2:
SP3: -
SP4: - - -
SP5:

Relevant External Links for KIAA0355 Gene

GeneLoc Exon Structure for
KIAA0355
ECgene alternative splicing isoforms for
KIAA0355

Expression for KIAA0355 Gene

mRNA expression in normal human tissues for KIAA0355 Gene

Protein differential expression in normal tissues from HIPED for KIAA0355 Gene

This gene is overexpressed in Placenta (40.0) and Testis (24.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for KIAA0355 Gene



SOURCE GeneReport for Unigene cluster for KIAA0355 Gene Hs.330073

genes like me logo Genes that share expression patterns with KIAA0355: view

Protein tissue co-expression partners for KIAA0355 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KIAA0355 Gene

Orthologs for KIAA0355 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0355 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia KIAA0355 35
  • 91.09 (n)
  • 95.05 (a)
KIAA0355 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA0355 35
  • 91.33 (n)
  • 95.31 (a)
KIAA0355 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4931406P16Rik 35
  • 89.89 (n)
  • 93.57 (a)
4931406P16Rik 16
4931406P16Rik 36
  • 94 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia KIAA0355 35
  • 99.38 (n)
  • 99.63 (a)
KIAA0355 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1308428 35
  • 89.64 (n)
  • 93.2 (a)
oppossum
(Monodelphis domestica)
Mammalia KIAA0355 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0355 36
  • 81 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0355 35
  • 74.92 (n)
  • 81.14 (a)
KIAA0355 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA0355 36
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0355 35
  • 70.81 (n)
  • 75.36 (a)
Str.19353 35
zebrafish
(Danio rerio)
Actinopterygii KIAA0355 36
  • 64 (a)
OneToOne
Species with no ortholog for KIAA0355:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0355 Gene

ENSEMBL:
Gene Tree for KIAA0355 (if available)
TreeFam:
Gene Tree for KIAA0355 (if available)

Paralogs for KIAA0355 Gene

No data available for Paralogs for KIAA0355 Gene

Variants for KIAA0355 Gene

Sequence variations from dbSNP and Humsavar for KIAA0355 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7258393 -- 34,344,364(+) ggcgg(A/G)cggat intron-variant
rs7259326 -- 34,344,365(+) gcggg(C/T)ggatc intron-variant
rs12977034 -- 34,301,587(+) TTTCA(A/G)ATTTT intron-variant
rs7408565 -- 34,302,140(+) catgc(A/G)ccacc intron-variant
rs8101748 -- 34,331,426(+) CTCCT(C/G)CAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA0355 Gene

Variant ID Type Subtype PubMed ID
nsv509737 CNV Insertion 20534489
nsv2468 CNV Insertion 18451855
nsv509738 CNV Insertion 20534489

Variation tolerance for KIAA0355 Gene

Residual Variation Intolerance Score: 10% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.37; 53.96% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for KIAA0355 Gene

Disorders for KIAA0355 Gene

Relevant External Links for KIAA0355

Genetic Association Database (GAD)
KIAA0355
Human Genome Epidemiology (HuGE) Navigator
KIAA0355
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA0355

No disorders were found for KIAA0355 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0355 Gene

Publications for KIAA0355 Gene

  1. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T. … Ohara O. (DNA Res. 1997) 2 3 4 67
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  3. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  4. A systems-wide screen identifies substrates of the SCFI^TrCP ubiquitin ligase. (PMID: 25515538) Low T.Y. … Heck A.J. (Sci Signal 2014) 3
  5. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PMID: 24255178) Couzens A.L. … Gingras A.C. (Sci Signal 2013) 3

Products for KIAA0355 Gene

Sources for KIAA0355 Gene

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