Aliases for KIAA0232 Gene
External Ids for KIAA0232 Gene
- HGNC: 28992
- Entrez Gene: 9778
- Ensembl: ENSG00000170871
- UniProtKB: Q92628
Previous GeneCards Identifiers for KIAA0232 Gene
- GC04P006690
- GC04P006906
- GC04P006849
- GC04P006902
- GC04P006715
Summaries for KIAA0232 Gene
GeneCards Summary for KIAA0232 Gene
KIAA0232 (KIAA0232) is a Protein Coding gene.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0232 Gene
Genomics for KIAA0232 Gene
Regulatory Elements for KIAA0232 Gene
Enhancers for KIAA0232 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around KIAA0232 on UCSC Golden Path with GeneCards custom track
Promoters for KIAA0232 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around KIAA0232 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the KIAA0232 gene promoter:
Regulatory Element Products
Genomic Location for KIAA0232 Gene
- Chromosome:
- 4
- Start:
- 6,781,375 bp from pter
- End:
- 6,884,172 bp from pter
- Size:
- 102,798 bases
- Orientation:
- Plus strand
Genomic View for KIAA0232 Gene
Genes around KIAA0232 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.1 by Ensembl
- 4p16.1 by Entrez Gene
- 4p16.1 by HGNC
KIAA0232 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KIAA0232 Gene
Proteins for KIAA0232 Gene
-
Protein details for KIAA0232 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92628-K0232_HUMAN
- Recommended name:
- Uncharacterized protein KIAA0232
- Protein Accession:
- Q92628
- A7E2D2
Protein attributes for KIAA0232 Gene
- Size:
- 1395 amino acids
- Molecular mass:
- 154789 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA13221.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for KIAA0232 Gene
Post-translational modifications for KIAA0232 Gene
Other Protein References for KIAA0232 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for KIAA0232
- Search GeneTex for Antibodies for KIAA0232
-
Santa Cruz Biotechnology (SCBT) Antibodies for KIAA0232
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for KIAA0232
- Origene Custom Protein Services for KIAA0232
- Novus Biologicals proteins for KIAA0232
- Search GeneTex for Proteins for KIAA0232
Assay Products
No data available for DME Specific Peptides for KIAA0232 Gene
Domains & Families for KIAA0232 Gene
Suggested Antigen Peptide Sequences for KIAA0232 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for KIAA0232 Gene
Function for KIAA0232 Gene
Phenotypes for KIAA0232 Gene
- GenomeRNAi human phenotypes for KIAA0232:
-
- Increased transferrin (TF) endocytosis
- FOXO1 nuclear localization
- Decreased Hepatitis C virus replication
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for KIAA0232 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
- Search ViGene Biosciences for KIAA0232
CRISPR Products
-
OriGene CRISPR knockouts for KIAA0232
-
Santa Cruz Biotechnology (SCBT) CRISPR for KIAA0232
- GenScript: Design CRISPR guide RNA sequences for KIAA0232
miRNA for KIAA0232 Gene
- miRTarBase miRNAs that target KIAA0232
-
- hsa-mir-375 (MIRT019736)
- hsa-mir-26b-5p (MIRT029109)
- hsa-mir-106b-3p (MIRT038590)
- hsa-mir-125a-5p (MIRT045711)
- hsa-mir-17-5p (MIRT213320)
- hsa-mir-20a-5p (MIRT213321)
- hsa-mir-93-5p (MIRT213322)
- hsa-mir-106a-5p (MIRT213323)
- hsa-mir-106b-5p (MIRT213324)
- hsa-mir-20b-5p (MIRT213325)
- hsa-mir-526b-3p (MIRT213327)
- hsa-mir-519d-3p (MIRT213328)
- hsa-mir-3609 (MIRT213330)
- hsa-mir-548ah-5p (MIRT213334)
- hsa-mir-4796-3p (MIRT213335)
- hsa-mir-152-3p (MIRT437644)
- hsa-mir-362-3p (MIRT541776)
- hsa-mir-329-3p (MIRT541777)
- hsa-mir-8485 (MIRT541778)
- hsa-mir-3689f (MIRT572509)
- hsa-mir-3689e (MIRT572510)
- hsa-mir-3689b-5p (MIRT572511)
- hsa-mir-3689a-5p (MIRT572512)
- hsa-mir-142-3p (MIRT572513)
- hsa-mir-6073 (MIRT572514)
- hsa-mir-190a-5p (MIRT572515)
- hsa-mir-190b (MIRT572516)
- hsa-mir-20b-3p (MIRT572517)
- hsa-mir-1208 (MIRT572518)
- hsa-mir-6760-3p (MIRT572519)
- hsa-mir-8062 (MIRT572520)
- hsa-mir-8079 (MIRT572521)
- hsa-mir-1245a (MIRT572522)
- hsa-mir-1183 (MIRT572523)
- hsa-mir-1224-3p (MIRT609807)
miRNA Products
- Search ViGene Biosciences for KIAA0232
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for KIAA0232
- Browse OriGene Inhibitory RNA Products For KIAA0232
-
ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
Clone Products
- OriGene clones in human for KIAA0232
- OriGene ORF clones in human for KIAA0232
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for KIAA0232 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for KIAA0232 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0232 Gene
Localization for KIAA0232 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| nucleus | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0232 Gene
Pathways & Interactions for KIAA0232 Gene
More details on SuperPathways for KIAA0232
No Data Available
Interacting Proteins for KIAA0232 Gene
Selected Interacting proteins:
Q92628-K0232_HUMAN
ENSP00000303928
for KIAA0232 Gene via
MINT
STRING
I2D
No data available for Pathways by source and SIGNOR curated interactions for KIAA0232 Gene
Transcripts for KIAA0232 Gene
mRNA/cDNA for KIAA0232 Gene
- (6) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (230) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for KIAA0232
-
Santa Cruz Biotechnology (SCBT) CRISPR for KIAA0232
- GenScript: Design CRISPR guide RNA sequences for KIAA0232
miRNA Products
- Search ViGene Biosciences for KIAA0232
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for KIAA0232
- Browse OriGene Inhibitory RNA Products For KIAA0232
-
ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
Clone Products
- OriGene clones in human for KIAA0232
- OriGene ORF clones in human for KIAA0232
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for KIAA0232 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
This gene is overexpressed in Bone (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for KIAA0232 Gene
SOURCE GeneReport for Unigene cluster for KIAA0232 Gene Hs.79276
Primer Products
-
OriGene qPCR primer pairs for KIAA0232
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KIAA0232 Gene
Orthologs for KIAA0232 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | KIAA0232 35 |
|
||
| KIAA0232 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | KIAA0232 35 |
|
||
| KIAA0232 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | D5Ertd579e 35 |
|
||
| D5Ertd579e 16 |
|
||||
| D5Ertd579e 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | KIAA0232 35 |
|
||
| KIAA0232 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | LOC680039 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KIAA0232 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | KIAA0232 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | KIAA0232 35 |
|
||
| KIAA0232 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | KIAA0232 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | kiaa0232 35 |
|
||
| Str.10272 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.30950 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | wufc44c06 35 |
|
||
| zgc:158564 36 |
|
OneToOne | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.120 36 |
|
OneToOne |
- Species with no ortholog for KIAA0232:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KIAA0232 Gene
No data available for Paralogs for KIAA0232 Gene
Variants for KIAA0232 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10138 | -- | 6,883,354(+) | AAATA(A/G)AAATT | utr-variant-3-prime | |
| rs874893 | -- | 6,801,833(-) | ATCCT(C/T)GCAGG | intron-variant | |
| rs875630 | -- | 6,848,797(-) | GTACA(C/T)AATGT | intron-variant | |
| rs875631 | -- | 6,848,658(-) | tatat(C/T)gggtc | intron-variant | |
| rs879326 | -- | 6,801,154(+) | tggaa(A/G)tgttc | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv34196 | OTHER | Inversion | 12058347 |
| esv23947 | CNV | Loss | 19812545 |
| nsv526314 | CNV | Gain | 19592680 |
| nsv519565 | CNV | Gain+Loss | 19592680 |
| nsv4216 | CNV | Loss | 18451855 |
| esv2727009 | CNV | Deletion | 23290073 |
| esv2727010 | CNV | Deletion | 23290073 |
| esv1098216 | CNV | Insertion | 17803354 |
| esv23110 | CNV | Gain | 19812545 |
| dgv859e201 | CNV | Deletion | 23290073 |
| esv2727011 | CNV | Deletion | 23290073 |
| esv1704198 | CNV | Insertion | 17803354 |
| nsv878529 | CNV | Loss | 21882294 |
Residual Variation Intolerance Score:
6.13% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.49;
64.42% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for KIAA0232 Gene
- Human Gene Mutation Database (HGMD)
- KIAA0232
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0232 Gene
Disorders for KIAA0232 Gene
Relevant External Links for KIAA0232
No disorders were found for KIAA0232 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0232 Gene
Publications for KIAA0232 Gene
- Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T. … Nomura N. (DNA Res. 1996) 2 3 4 67
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
- A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. (PMID: 24026423) Shameer K. … Kullo I.J. (Hum. Genet. 2014) 3
- The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3
- New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C. … Soranzo N. (Nature 2011) 3
Products for KIAA0232 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for KIAA0232
- Origene Custom Protein Services for KIAA0232
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for KIAA0232
- Browse OriGene Inhibitory RNA Products For KIAA0232
- OriGene qPCR primer pairs for KIAA0232
- OriGene CRISPR knockouts for KIAA0232
- OriGene clones in human for KIAA0232
- OriGene ORF clones in human for KIAA0232
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for KIAA0232
- GenScript Custom Assay Services for KIAA0232
- GenScript Custom overexpressing Cell Line Services for KIAA0232
- GenScript: Design CRISPR guide RNA sequences for KIAA0232
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for KIAA0232
- Novus Biologicals Antibodies for KIAA0232
- Novus Biologicals proteins for KIAA0232
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for KIAA0232 gene
- ViGene Biosciences lentiviral particle packaged cDNA for KIAA0232 gene
- ViGene Biosciences lentiviral particle packaged cDNA for KIAA0232 gene
- ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
- ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
- ViGene Biosciences ready-to-package AAV shRNAs for KIAA0232 gene
- Search ViGene Biosciences for KIAA0232
- Search ViGene Biosciences for KIAA0232
- Santa Cruz Biotechnology (SCBT) Antibodies for KIAA0232
- Search Santa Cruz Biotechnology (SCBT) for KIAA0232 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KIAA0232
Sources for KIAA0232 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon