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Aliases for KIAA0232 Gene

Aliases for KIAA0232 Gene

  • KIAA0232 2 3

External Ids for KIAA0232 Gene

Previous GeneCards Identifiers for KIAA0232 Gene

  • GC04P006690
  • GC04P006906
  • GC04P006849
  • GC04P006902
  • GC04P006715

Summaries for KIAA0232 Gene

GeneCards Summary for KIAA0232 Gene

KIAA0232 (KIAA0232) is a Protein Coding gene.

Additional gene information for KIAA0232 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0232 Gene

Genomics for KIAA0232 Gene

GeneHancer (GH) Regulatory Elements for KIAA0232 Gene

Promoters and enhancers for KIAA0232 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I006781 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 561.4 +1.3 1255 3.2 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 POLR2B ZNF207 ZNF143 SP3 SP5 KIAA0232 TADA2B TBC1D14 GC04P006772 GC04P006842
GH04I006779 Enhancer 1 Ensembl ENCODE 550.8 -1.3 -1275 0.6 ELF3 FOXA2 ARID4B ZSCAN9 RAD21 RARA ZNF335 GLIS2 HSF1 THAP11 KIAA0232 GC04P006772
GH04I006914 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 24.7 +135.3 135264 5.1 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B NEUROD1 SIN3A FEZF1 DMAP1 KIAA0232 TBC1D14 BLOC1S4 GRPEL1 TADA2B MAN2B2 S100P GC04M006908 GC04P006943
GH04I006908 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.6 +128.7 128694 3.6 HDGF PKNOX1 ARID4B SIN3A DMAP1 YY1 ZNF766 E2F8 ZNF207 ZNF143 TBC1D14 GC04M006908 PIR60819 KIAA0232 GRPEL1 TADA2B GC04P006943
GH04I006806 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 17.6 +26.2 26226 3.2 HDAC1 LEF1 TAL1 FOSL1 TCF12 GATA3 ZNF316 NCOR1 CBFA2T2 FOS KIAA0232 TBC1D14 TADA2B GC04P006842
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around KIAA0232 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KIAA0232 gene promoter:

Genomic Locations for KIAA0232 Gene

Genomic Locations for KIAA0232 Gene
chr4:6,781,375-6,884,172
(GRCh38/hg38)
Size:
102,798 bases
Orientation:
Plus strand
chr4:6,783,102-6,885,899
(GRCh37/hg19)

Genomic View for KIAA0232 Gene

Genes around KIAA0232 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0232 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0232 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0232 Gene

Proteins for KIAA0232 Gene

  • Protein details for KIAA0232 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q92628-K0232_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0232
    Protein Accession:
    Q92628
    Secondary Accessions:
    • A7E2D2

    Protein attributes for KIAA0232 Gene

    Size:
    1395 amino acids
    Molecular mass:
    154789 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA13221.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for KIAA0232 Gene

Post-translational modifications for KIAA0232 Gene

No Post-translational modifications

No data available for DME Specific Peptides for KIAA0232 Gene

Domains & Families for KIAA0232 Gene

Gene Families for KIAA0232 Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for KIAA0232 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA0232 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0232: view

No data available for UniProtKB/Swiss-Prot for KIAA0232 Gene

Function for KIAA0232 Gene

Phenotypes From GWAS Catalog for KIAA0232 Gene

Gene Ontology (GO) - Molecular Function for KIAA0232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with KIAA0232: view
genes like me logo Genes that share phenotypes with KIAA0232: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0232 Gene

Localization for KIAA0232 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA0232 gene
Compartment Confidence
cytosol 3
nucleus 2

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0232 Gene

Pathways & Interactions for KIAA0232 Gene

SuperPathways for KIAA0232 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA0232 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0232 Gene

Drugs & Compounds for KIAA0232 Gene

No Compound Related Data Available

Transcripts for KIAA0232 Gene

Unigene Clusters for KIAA0232 Gene

KIAA0232:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0232 Gene

No ASD Table

Relevant External Links for KIAA0232 Gene

GeneLoc Exon Structure for
KIAA0232
ECgene alternative splicing isoforms for
KIAA0232

Expression for KIAA0232 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA0232 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KIAA0232 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA0232 Gene



Protein tissue co-expression partners for KIAA0232 Gene

NURSA nuclear receptor signaling pathways regulating expression of KIAA0232 Gene:

KIAA0232

SOURCE GeneReport for Unigene cluster for KIAA0232 Gene:

Hs.79276

Evidence on tissue expression from TISSUES for KIAA0232 Gene

  • Bone marrow(4.2)
  • Liver(4.2)
  • Nervous system(2.8)
  • Heart(2)
genes like me logo Genes that share expression patterns with KIAA0232: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA0232 Gene

Orthologs for KIAA0232 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0232 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0232 33 34
  • 99.83 (n)
oppossum
(Monodelphis domestica)
Mammalia KIAA0232 34
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA0232 33 34
  • 88.86 (n)
rat
(Rattus norvegicus)
Mammalia LOC680039 33
  • 88.59 (n)
mouse
(Mus musculus)
Mammalia D5Ertd579e 33 16 34
  • 88.53 (n)
cow
(Bos Taurus)
Mammalia KIAA0232 33 34
  • 84.66 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0232 34
  • 75 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0232 33 34
  • 84.51 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA0232 34
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0232 33
  • 70.02 (n)
Str.10272 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.30950 33
zebrafish
(Danio rerio)
Actinopterygii zgc:158564 34
  • 57 (a)
OneToOne
wufc44c06 33
sea squirt
(Ciona savignyi)
Ascidiacea CSA.120 34
  • 27 (a)
OneToOne
Species where no ortholog for KIAA0232 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0232 Gene

ENSEMBL:
Gene Tree for KIAA0232 (if available)
TreeFam:
Gene Tree for KIAA0232 (if available)

Paralogs for KIAA0232 Gene

No data available for Paralogs for KIAA0232 Gene

Variants for KIAA0232 Gene

Sequence variations from dbSNP and Humsavar for KIAA0232 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000002594 -- 6,795,849(+) C/T genic_upstream_transcript_variant, intron_variant
rs1000009897 -- 6,787,106(+) G/A genic_upstream_transcript_variant, intron_variant
rs1000015413 -- 6,869,978(+) G/A intron_variant
rs1000047904 -- 6,870,135(+) G/T intron_variant
rs1000054699 -- 6,826,829(+) G/A genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA0232 Gene

Variant ID Type Subtype PubMed ID
dgv2722n106 CNV deletion 24896259
dgv812e201 CNV deletion 23290073
dgv8937n54 CNV gain+loss 21841781
dgv8938n54 CNV gain 21841781
dgv8939n54 CNV loss 21841781
dgv8940n54 CNV gain 21841781
esv1098216 CNV insertion 17803354
esv1704198 CNV insertion 17803354
esv23110 CNV gain 19812545
esv23947 CNV loss 19812545
esv2727009 CNV deletion 23290073
esv2727010 CNV deletion 23290073
esv2727011 CNV deletion 23290073
esv34196 OTHER inversion 12058347
esv3563336 CNV deletion 23714750
esv3599511 CNV loss 21293372
nsv1010710 CNV gain 25217958
nsv1112848 CNV deletion 24896259
nsv4216 CNV deletion 18451855
nsv519565 CNV gain+loss 19592680
nsv526314 CNV gain 19592680
nsv593525 CNV loss 21841781
nsv593526 CNV gain 21841781
nsv593527 CNV gain 21841781
nsv593532 CNV gain 21841781
nsv949779 CNV duplication 24416366

Variation tolerance for KIAA0232 Gene

Residual Variation Intolerance Score: 6.13% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.49; 64.42% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIAA0232 Gene

Human Gene Mutation Database (HGMD)
KIAA0232
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA0232

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0232 Gene

Disorders for KIAA0232 Gene

Additional Disease Information for KIAA0232

No disorders were found for KIAA0232 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0232 Gene

Publications for KIAA0232 Gene

  1. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T … Nomura N (DNA research : an international journal for rapid publication of reports on genes and genomes 1996) 2 3 4 58
  2. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 3 44 58
  3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 58
  4. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D … Nagase T (DNA research : an international journal for rapid publication of reports on genes and genomes 2002) 3 4 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for KIAA0232 Gene

Sources for KIAA0232 Gene

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