KIAA0232 Gene
protein-coding GIFtS: 42
GCID: GC04P006783
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KIAA0232
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Aliases
for KIAA0232 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| KIAA02321 2 | | Uncharacterized Protein KIAA02322 |
Export aliases for KIAA0232 gene to outside databasesPrevious GC identifers: GC04P006690 GC04P006906 GC04P006849 GC04P006902 GC04P006715 |
Summaries
for KIAA0232 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for KIAA0232 Gene: 
KIAA0232 (KIAA0232) is a protein-coding gene. GO annotations related to this gene include ATP binding.
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Genomic Views
for KIAA0232 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NT_006051.18 NC_018915.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA0232 gene promoter:
Max1 ER-alpha STAT5B STAT1 Pax-6 STAT1alpha Gfi-1 MZF-1 Pax-3 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA0232
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0232 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.1 Ensembl cytogenetic band: 4p16.1 HGNC cytogenetic band: 4p16.1KIAA0232 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P006783: view genomic region
(about GC identifiers)
Start:
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6,783,102 bp from pter |
End:
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6,885,899 bp from pter |
Size:
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102,798 bases |
Orientation:
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plus strand |
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Proteins
for KIAA0232 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: K0232_HUMAN, Q92628 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA0232 Size: 1395 amino acids; 154789 Da
Sequence caution: Sequence=BAA13221.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A7E2D2Explore the universe of human proteins at neXtProt for KIAA0232: NX_Q92628
Explore proteomics data for KIAA0232 at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q92628
KIAA0232 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001094060.1 NP_055558.2
ENSEMBL proteins: ENSP00000426815 ENSP00000303928 ENSP00000413739
Human Recombinant Protein Products for KIAA0232:
KIAA0232 Antibody Products:
Assay Products for KIAA0232: |
Protein
Domains /
Families
for KIAA0232 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q92628 |
Function
for KIAA0232 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005524 | ATP binding |
IEA | -- |
KIAA0232 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for KIAA0232:
Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0232 |
|
Pathways & Interactions
for KIAA0232 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA0232
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5 Interacting proteins for KIAA0232 (Q926282, 3 ENSP000003039284) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for KIAA0232 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
IUPHAR,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA0232 (K0232)
Search CenterWatch for drugs/clinical trials and news about KIAA0232 / K0232
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Transcripts
for KIAA0232 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIAA0232 gene (2 alternative transcripts): NM_001100590.1 NM_014743.2 Unigene Cluster for KIAA0232: KIAA0232 Hs.79276 [show with all ESTs]Unigene Representative Sequence: NM_0147435 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000503278 ENST00000508423 ENST00000307659(uc003gjr.4) ENST00000503069
ENST00000425103(uc003gjq.4)
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for KIAA0232
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA0232 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0232 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0232 |
Additional mRNA sequence: AF143884.1 AK124715.1 BC150286.1 CR457160.1 D86985.3 EF553521.1 8 DOTS entries: DT.118111 DT.91701977 DT.100700972 DT.100785040 DT.121260491 DT.92433565 DT.100012762 DT.121260484 24/230 AceView cDNA sequences (see all 230): AI468228 BG387474 CD679592 AA663574 BU741773 BU178853 BM128586 AI434782 AW069515 BM683617 D86985 BE501060 AA256519 BQ184741 BM678073 T33116 AI824920 AA421928 BM311982 BQ000832 CK300683 BU618566 AA702636 W73363
GeneLoc Exon Structure
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Expression
for KIAA0232 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA0232 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GAAAATGGAA
About this image
See KIAA0232 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA0232
SOURCE GeneReport for Unigene cluster: Hs.79276
SABiosciences Custom PCR Arrays for KIAA0232
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for KIAA0232
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA0232 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0232 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0232 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0232 |
Orthologs
for KIAA0232 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KIAA0232 gene from 5/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
D5Ertd579e1 , 5 |
DNA segment, Chr 5, ERATO Doi 579, expressed1, 5 |
88.53(n)1
88.72(a)1 |
|
5 (19.18 cM)5
3206611 NM_001081232.21 NP_001074701.21
365847885 |
chicken
(Gallus gallus) |
Aves |
KIAA02321 |
KIAA0232 |
84.51(n)
86.51(a) |
|
422860 XM_420806.2 XP_420806.2 |
lizard
(Anolis carolinensis) |
Reptilia |
KIAA02326 |
KIAA0232 |
73(a) |
1 ↔ 1 |
4(79398811-79457388) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.309502 |
Xenopus laevis transcribed sequences |
80.57(n) |
|
48033214 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc44c062 |
Transcribed sequence with weak similarity to protein more |
70.1(n) |
|
57050020 |
ENSEMBL Gene Tree for KIAA0232 (if available)
TreeFam Gene Tree for KIAA0232 (if available) |
Paralogs
for KIAA0232 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KIAA0232 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIAA0232 (6783102 - 6885899 bp)
Structural Variations
Database of Genomic Variants (DGV) 10/13 variations for KIAA0232 (see all 13): About this table
Human Gene Mutation Database (HGMD): KIAA0232
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA0232 |
|
Disorders
/ Diseases
for KIAA0232 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 KIAA0232 for disorders About MalaCards
KIAA0232 for disorders About GeneDecksing
Genetic Association Database (GAD): KIAA0232
Export disorders for KIAA0232 gene to outside databases
|
Publications
for KIAA0232 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA0232 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with KIAA0232) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2, 3 Nagase T....Nomura N. (1996)
- New gene functions in megakaryopoiesis and platelet fo rmation. (PubMed id 22139419)1, 4 Gieger C....Soranzo N. (2011)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for KIAA0232 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA0232 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIAA0232 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA0232 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA0232 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KIAA0232 gene:
Search GeneIP for patents involving KIAA0232
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA0232 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA0232 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA0232 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA0232 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA0232 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA0232 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA0232 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA0232 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for KIAA0232 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA0232 |
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