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Aliases for KIAA0195 Gene

Aliases for KIAA0195 Gene

  • KIAA0195 2 3
  • Transmembrane Protein 94 3 4
  • TMEM94 3 4
  • Uncharacterized Protein KIAA0195 3

External Ids for KIAA0195 Gene

Previous GeneCards Identifiers for KIAA0195 Gene

  • GC17U990148
  • GC17P076507
  • GC17P073916
  • GC17P074050
  • GC17P074051
  • GC17P070964
  • GC17P073452
  • GC17P068876

Summaries for KIAA0195 Gene

GeneCards Summary for KIAA0195 Gene

KIAA0195 (KIAA0195) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0195 Gene

Genomics for KIAA0195 Gene

Regulatory Elements for KIAA0195 Gene

Genomic Location for KIAA0195 Gene

Start:
75,441,159 bp from pter
End:
75,500,452 bp from pter
Size:
59,294 bases
Orientation:
Plus strand

Genomic View for KIAA0195 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA0195 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0195 Gene

Proteins for KIAA0195 Gene

  • Protein details for KIAA0195 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q12767-K0195_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0195
    Protein Accession:
    Q12767
    Secondary Accessions:
    • O75536
    • Q86XF1

    Protein attributes for KIAA0195 Gene

    Size:
    1356 amino acids
    Molecular mass:
    151151 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA12108.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA0195 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0195 Gene

Proteomics data for KIAA0195 Gene at MOPED

Post-translational modifications for KIAA0195 Gene

  • Ubiquitination at Lys6, Lys644, and Lys648
  • Glycosylation at Asn475, Asn516, Asn1202, and Asn1205
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for KIAA0195 Gene

Domains for KIAA0195 Gene

Protein Domains for KIAA0195 Gene

Suggested Antigen Peptide Sequences for KIAA0195 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA0195: view

No data available for Gene Families and UniProtKB/Swiss-Prot for KIAA0195 Gene

Function for KIAA0195 Gene

Molecular function for KIAA0195 Gene

GENATLAS Biochemistry: Null

Phenotypes for KIAA0195 Gene

MGI mutant phenotypes for KIAA0195:
inferred from 1 alleles
GenomeRNAi human phenotypes for KIAA0195:
genes like me logo Genes that share phenotypes with KIAA0195: view

miRNA for KIAA0195 Gene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA0195 Gene

Localization for KIAA0195 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIAA0195 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA0195 Gene COMPARTMENTS Subcellular localization image for KIAA0195 gene
Compartment Confidence
plasma membrane 3
nucleus 2

Gene Ontology (GO) - Cellular Components for KIAA0195 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with KIAA0195: view

Pathways for KIAA0195 Gene

SuperPathways for KIAA0195 Gene

No Data Available

Interacting Proteins for KIAA0195 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000313885%0d%0a9606.ENSP00000419782%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000313885 Q12767-K0195_HUMAN for KIAA0195 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for KIAA0195 Gene

None

No data available for Pathways by source for KIAA0195 Gene

Transcripts for KIAA0195 Gene

Unigene Clusters for KIAA0195 Gene

KIAA0195:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0195 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14a · 14b · 14c · 14d ^ 15a · 15b · 15c ·
SP1: - - - -
SP2:
SP3:
SP4: - - -
SP5: - - - - -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12: -
SP13: - - - - -
SP14:
SP15:
SP16:
SP17: - - -
SP18: -
SP19: - - - -
SP20:
SP21:
SP22:

ExUns: 15d ^ 16a · 16b · 16c · 16d ^ 17a · 17b · 17c · 17d ^ 18a · 18b · 18c ^ 19a · 19b ^ 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24a · 24b · 24c ^ 25a · 25b ^ 26 ^ 27 ^
SP1: - - - - -
SP2:
SP3:
SP4: -
SP5: - - - - -
SP6: -
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13: -
SP14:
SP15: -
SP16:
SP17: - -
SP18:
SP19: - -
SP20:
SP21:
SP22: -

ExUns: 28 ^ 29a · 29b ^ 30a · 30b · 30c ^ 31 ^ 32a · 32b · 32c ^ 33a · 33b
SP1: - -
SP2: -
SP3:
SP4:
SP5:
SP6:
SP7: -
SP8:
SP9:
SP10: -
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:

Relevant External Links for KIAA0195 Gene

GeneLoc Exon Structure for
KIAA0195
ECgene alternative splicing isoforms for
KIAA0195

Expression for KIAA0195 Gene

mRNA expression in normal human tissues for KIAA0195 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KIAA0195 Gene

SOURCE GeneReport for Unigene cluster for KIAA0195 Gene Hs.514474

mRNA Expression by UniProt/SwissProt for KIAA0195 Gene

Q12767-K0195_HUMAN
Tissue specificity: Expressed ubiquitously.
genes like me logo Genes that share expressions with KIAA0195: view

No data available for mRNA differential expression in normal tissues for KIAA0195 Gene

Orthologs for KIAA0195 Gene

This gene was present in the common ancestor of animals.

Orthologs for KIAA0195 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0195 35
  • 99.63 (n)
  • 99.63 (a)
KIAA0195 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA0195 35
  • 90.36 (n)
  • 94.21 (a)
KIAA0195 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA0195 35
  • 90.81 (n)
  • 95.8 (a)
KIAA0195 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310067B10Rik 35
  • 89.28 (n)
  • 95.5 (a)
2310067B10Rik 16
2310067B10Rik 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA0195 36
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0195 36
  • 84 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0195 35
  • 75.98 (n)
  • 82.77 (a)
KIAA0195 36
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA0195 36
  • 81 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0195 35
  • 70.58 (n)
  • 71.99 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC795408 35
  • 67.47 (n)
  • 69.13 (a)
si:dkeyp-67e6.4 36
  • 68 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000576 35
  • 50.34 (n)
  • 38.27 (a)
fruit fly
(Drosophila melanogaster)
Insecta l(2)k05819 35
  • 48.98 (n)
  • 37.58 (a)
l(2)k05819 36
  • 30 (a)
OneToOne
l(2)k05819 37
  • 38 (a)
worm
(Caenorhabditis elegans)
Secernentea D1007.15 35
  • 41.03 (n)
  • 33.06 (a)
D1007.15 36
  • 27 (a)
OneToOne
D1007.15 37
  • 29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
OneToMany
-- 36
  • 23 (a)
OneToMany
Species with no ortholog for KIAA0195:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KIAA0195 Gene

ENSEMBL:
Gene Tree for KIAA0195 (if available)
TreeFam:
Gene Tree for KIAA0195 (if available)

Paralogs for KIAA0195 Gene

No data available for Paralogs for KIAA0195 Gene

Variants for KIAA0195 Gene

Sequence variations from dbSNP and Humsavar for KIAA0195 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs13357 -- 75,499,611(-) TTAGG(C/G)CCCCT utr-variant-3-prime
rs3934780 -- 75,469,235(-) AGAAC(A/G)AGGCA intron-variant
rs3935674 -- 75,477,378(-) GGAAG(C/G)GACAC intron-variant
rs4073989 -- 75,454,781(+) AGGGA(A/G)Aggct upstream-variant-2KB
rs4073990 -- 75,454,843(+) GAGGA(C/T)TGCTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for KIAA0195 Gene

Variant ID Type Subtype PubMed ID
nsv833541 CNV Loss 17160897
nsv516133 CNV Loss 19592680
nsv908762 CNV Loss 21882294
nsv833542 CNV Loss 17160897
nsv908763 CNV Gain 21882294
dgv3256n71 CNV Loss 21882294
nsv470603 CNV Loss 18288195
dgv3257n71 CNV Loss 21882294

Relevant External Links for KIAA0195 Gene

HapMap Linkage Disequilibrium report
KIAA0195

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA0195 Gene

Disorders for KIAA0195 Gene

Relevant External Links for KIAA0195

Genetic Association Database (GAD)
KIAA0195
Human Genome Epidemiology (HuGE) Navigator
KIAA0195
genes like me logo Genes that share disorders with KIAA0195: view

No data available for UniProtKB/Swiss-Prot for KIAA0195 Gene

Publications for KIAA0195 Gene

  1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8724849) Nagase T. … Nomura N. (DNA Res. 1996) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for KIAA0195 Gene

Sources for KIAA0195 Gene

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