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KIAA0101 Gene

protein-coding   GIFtS: 53
GCID: GC15M064657

KIAA0101

  See KIAA0101-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
KIAA01011 2     p15PAF2 3
PAF2 3 5     PCNA-Associated Factor Of 15 KDa2 3
Hepatitis C Virus NS5A-Transactivated Protein 92 3     OEATC12 5
Overexpressed In Anaplastic Thyroid Carcinoma 12 3     OEATC2
NS5ATP92 3     p15(PAF)2
OEATC-12 3     p15/PAF2
PAF152 3     PCNA-Associated Factor2
HCV NS5A-Transactivated Protein 92 3     

External Ids:    HGNC: 289611   Entrez Gene: 97682   Ensembl: ENSG000001668037   OMIM: 6106965   UniProtKB: Q150043   

Export aliases for KIAA0101 gene to outside databases

Previous GC identifers: GC15M060468 GC15M057816 GC15M062171 GC15M062373 GC15M062444 GC15M041482


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KIAA0101 Gene:
KIAA0101 (KIAA0101) is a protein-coding gene. Diseases associated with KIAA0101 include hepatitis c, and hepatitis c virus. GO annotations related to this gene include chromatin binding.

UniProtKB/Swiss-Prot: PAF15_HUMAN, Q15004
Function: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA
damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and
the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of
replication-fork-blocking lesions. Also acts as a regulator of centrosome number

Gene Wiki entry for KIAA0101 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the KIAA0101 gene promoter:
         RORalpha1   Pbx1a   FOXO1a   c-Myb   IRF-1   FOXO1   Evi-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for KIAA0101

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIAA0101


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.31   Ensembl cytogenetic band:  15q22.31   HGNC cytogenetic band: 15q22

KIAA0101 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIAA0101 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M064657:  view genomic region     (about GC identifiers)

Start:
64,657,193 bp from pter      End:
64,679,886 bp from pter
Size:
22,694 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PAF15_HUMAN, Q15004 (See protein sequence)
Recommended Name: PCNA-associated factor  
Size: 111 amino acids; 11986 Da
Subunit: Interacts (when monoubiquitinated at Lys-15 and Lys-24) with PCNA. Interacts with isoform 2/p33ING1b of
ING1. Interacts with BRCA1
Developmental stage: Present only during S and G2 phases of the cell cycle. Peaks at the G2/M phase of the cell
cycle and drops rapidly at mitotic exit in an APC/C-dependent manner (at protein level)
Miscellaneous: Overexpression in adrenocortical neoplasms (ACC), may promote growth and invasion in adrenal cancer
(PubMed:22096502)
Sequence caution: Sequence=BAA03491.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NNU5 A8K3Y3 G9G694 G9G696
Alternative splicing: 2 isoforms:  Q15004-1   Q15004-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIAA0101: NX_Q15004

Explore proteomics data for KIAA0101 at MOPED

Post-translational modifications: 

  • Monoubiquitinated at Lys-15 and Lys-24 during normal S phase, promoting its association with PCNA. Also
    diubiquitinated at these 2 sites. Following DNA damage, monoubiquitin chains at Lys-15 and Lys-24 are probably
    extended, leading to disrupt the interaction with PCNA. Polyubiquitinated by the APC/C complex at the mitotic
    exit, leading to its degradation by the proteasome1
  • Ubiquitination2 at Lys15, Lys24, Lys63
  • Modification sites at PhosphoSitePlus

  • See KIAA0101 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001025160.1  NP_055551.1  

    ENSEMBL proteins: 
     ENSP00000300035   ENSP00000369608   ENSP00000452975   ENSP00000453527  

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    antibodies-online proteins for KIAA0101 (4 products) 

     
    antibodies-online peptides for KIAA0101

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q15004

    UniProtKB/Swiss-Prot: PAF15_HUMAN, Q15004
    Domain: The PIP-box mediates the interaction with PCNA (PubMed:21628590, PubMed:23000965)
    Domain: The KEN box is required for the association with the APC/C complex (PubMed:21628590)
    Domain: The D-box (destruction box) mediates the interaction with APC/C proteins, and acts as a recognition signal
    for degradation via the ubiquitin-proteasome pathway (By similarity)
    Domain: The initiation motif is required for efficient chain initiation by the APC/C complex E2 ligase UBE2C. It
    determines the rate of substrate's degradation without affecting its affinity for the APC/C, a mechanism used by
    the APC/C to control the timing of substrate proteolysis during the cell cycle (PubMed:21700221)


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PAF15_HUMAN, Q15004
    Function: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA
    damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and
    the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of
    replication-fork-blocking lesions. Also acts as a regulator of centrosome number
    Induction: By UV irradiation. By ATF3 in response to UV-stress

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding IDA--
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with KIAA0101           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for KIAA0101:
     Synthetic lethal with Ras 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for 2810417H13Rik):
     cellular  hematopoietic system  immune system 

    Find genes that share phenotypes with KIAA0101           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out 2810417H13Riktm1.1Lkd for KIAA0101

       genOway: Develop your customized and physiologically relevant rodent model for KIAA0101

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    Selected qRT-PCR Assays for microRNAs that regulate KIAA0101 (see all 27):
    hsa-miR-495 hsa-miR-429 hsa-miR-520d-5p hsa-miR-323b-3p hsa-miR-767-5p hsa-miR-371-5p hsa-miR-606 hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidKIAA0101 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PAF15_HUMAN, Q15004: Nucleus. Cytoplasm, perinuclear region. Note=Following DNA damage, localizes to DNA damage
    sites. Colocalizes with centrosomes in perinuclear region
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular3
    mitochondrion3
    plasma membrane2
    cytoskeleton1
    cytosol1
    endoplasmic reticulum1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0048471perinuclear region of cytoplasm IDA--

    Find genes that share ontologies with KIAA0101           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIAA0101
    Interactions:

        GeneGlobe Interaction Network for KIAA0101

    2 Interacting proteins for KIAA0101 (Q150043) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CASTP208103I2D: score=1 
    PCNAP120043I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication IDA--
    GO:0006974cellular response to DNA damage stimulus IDA--
    GO:0009411response to UV IDA--
    GO:0019985translesion synthesis IMP--
    GO:0051297centrosome organization IMP--

    Find genes that share ontologies with KIAA0101           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for KIAA0101 (PAF15)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KIAA0101 gene (2 alternative transcripts): 
    NM_001029989.2  NM_014736.5  

    Unigene Cluster for KIAA0101:

    KIAA0101
    Hs.81892  [show with all ESTs]
    Unigene Representative Sequence: AY358648
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000300035(uc002ank.3 uc002anl.3) ENST00000380258 ENST00000559519
    ENST00000558008 ENST00000558043 ENST00000560234 ENST00000559280 ENST00000558250

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    hsa-miR-495 hsa-miR-429 hsa-miR-520d-5p hsa-miR-323b-3p hsa-miR-767-5p hsa-miR-371-5p hsa-miR-606 hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidKIAA0101 3' UTR sequence
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    Additional mRNA sequence: 

    AF529370.1 AK290748.1 AY358648.1 AY598324.1 BC005832.2 BC007101.1 BC016782.1 D14657.1 

    17 DOTS entries:

    DT.427407  DT.100852729  DT.116647  DT.100876851  DT.100665641  DT.100665636  DT.91970685  DT.97783424 
    DT.121022675  DT.95373158  DT.121022729  DT.100665637  DT.91949999  DT.92462814  DT.121022715  DT.121022743 
    DT.121022765 

    Selected AceView cDNA sequences (see all 712):

    BE540505 CR595526 AL524795 BI256340 BC017236 H60720 BM758450 AA778075 
    R91106 BM758304 BM758292 AK025179 BQ424478 AI192481 AA330343 BX094416 
    BF508581 AA278879 CA421604 CB151528 BE504869 H89631 BM991941 BG109250 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0101 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
    SP1:                                -     -           -                     
    SP2:                                -     -                                 
    SP3:                                -     -     -     -                     
    SP4:                          -     -     -           -                     
    SP5:                                                                        


    ECgene alternative splicing isoforms for KIAA0101

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KIAA0101 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCTTTGCAA
    KIAA0101 Expression
    About this image


    KIAA0101 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Epithelial Cells
             Presumptive Podocytes Podocyte Layer
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
     
     Heart (Cardiovascular System)
             Cardiac Fibroblasts Myocardium
     
     Fibroblasts
             Cardiac Fibroblasts Myocardium
    KIAA0101 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIAA0101 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.81892

    UniProtKB/Swiss-Prot: PAF15_HUMAN, Q15004
    Tissue specificity: Expressed predominantly in liver, pancreas and placenta. Not detected in heart or brain.
    Highly expressed in a number of tumors, especially esophageal tumors, in anaplastic thyroid carcinomas,
    adrenocortical carcinomas, and in non-small-cell lung cancer lines

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KIAA0101 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 2810417H13Rik1 , 5 RIKEN cDNA 2810417H13 gene1, 5 84.85(n)1
    84.55(a)1
      9 (35.58 cM)5
    680261  NM_026515.21  NP_080791.21 
     658902375 
    lizard
    (Anolis carolinensis)
    Reptilia KIAA01016
    KIAA0101
    67(a)
    1 ↔ 1
    GL343490.1(454452-459042)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia kiaa01011 KIAA0101 63.11(n)
    71.84(a)
      448713  NM_001005130.2  NP_001005130.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.121452 Danio rerio, clone IMAGE5601466, mRNA 77.1(n)    BC046015.1 


    ENSEMBL Gene Tree for KIAA0101 (if available)
    TreeFam Gene Tree for KIAA0101 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KIAA0101 (see all 398)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs10332061,2
    C,F,A,H--44718195(-) TCGCTG/ATCATA 2 -- ds50019Minor allele frequency- A:0.20NA WA CSA EA 370
    rs10332051,2
    C,F,A,H--44718197(-) ATTCGG/CTATCA 2 -- ds500114Minor allele frequency- C:0.20MN NS EA NA WA CSA 968
    rs10332041,2
    C,H--44718258(-) GGCACG/ACACAG 2 -- ds500114Minor allele frequency- A:0.04NA WA CSA EA 377
    rs1845357561,2
    --44718259(+) TGTGTA/GTGCCA 2 -- ds50010--------
    rs1454957451,2
    C--44718316(+) TTTCT-/TTTC  
            
    TTTCT
    2 -- ds50010--------
    rs118559241,2
    C,F,H--44718363(+) gttcaG/Agctgg 2 -- ds50011Minor allele frequency- A:0.50NA 4
    rs1404832011,2
    --44718482(+) CCTGGC/TTCATT 2 -- ds50010--------
    rs1879485711,2
    --44718614(+) CTCAGC/TCTTTT 2 -- ds50010--------
    rs1931088141,2
    --44718735(+) GTTCAC/TGCCAT 2 -- ut310--------
    rs1853156631,2
    --44718793(+) CCGCGA/CCCGGC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for KIAA0101 (64657193 - 64679886 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for KIAA0101:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1497681CNV Deletion17803354
    esv2749782CNV Deletion23290073
    esv4243CNV Deletion18987735
    esv2749783CNV Deletion23290073
    esv2675981CNV Deletion23128226
    esv2319425CNV Deletion18987734
    esv267794CNV Insertion20981092
    nsv904306CNV Loss21882294
    nsv94581CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KIAA0101
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610696    OMIM disorders: --

    3 diseases for KIAA0101:    
    About MalaCards
    hepatitis c    hepatitis c virus    hepatitis

    5 diseases from the University of Copenhagen DISEASES database for KIAA0101:
    Asthma     Multiple system atrophy     Vascular disease     Eosinophilia
    Pleurisy

    Find genes that share disorders with KIAA0101           About GenesLikeMe


    Export disorders for KIAA0101 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KIAA0101 gene, integrated from 10 sources (see all 50):
    (articles sorted by number of sources associating them with KIAA0101)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues. (PubMed id 11313979)1, 2, 3, 9 Yu P.... Luo Y. (Oncogene 2001)
    2. The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b. (PubMed id 16288740)1, 2, 3 Simpson F.... Wicking C. (Exp. Cell Res. 2006)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1, 2 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    4. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate. (PubMed id 21628590)1, 2 Emanuele M.J.... Elledge S.J. (Proc. Natl. Acad. Sci. U.S.A. 2011)
    5. KIAA0101 interacts with BRCA1 and regulates centrosome number. (PubMed id 21673012)1, 2 Kais Z.... Parvin J.D. (Mol. Cancer Res. 2011)
    6. KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer. (PubMed id 22096502)1, 2 Jain M.... Kebebew E. (PLoS ONE 2011)
    7. ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress. (PubMed id 19219066)1, 2 Turchi L.... Virolle T. (Cell Death Differ. 2009)
    8. Overexpressed in anaplastic thyroid carcinoma-1 (OEATC-1) as a novel gene responsible for anaplastic thyroid carcinoma. (PubMed id 15789362)1, 2 Mizutani K.... Emi M. (Cancer 2005)
    9. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)1, 2 Petroziello J.... Carter P. (Oncogene 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 9768 HGNC: 28961 AceView: KIAA0101andCSNK1G1 Ensembl:ENSG00000166803 euGenes: HUgn9768
    ECgene: KIAA0101 H-InvDB: KIAA0101

    (According to HUGE)
    About This Section

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    HUGE: KIAA0101

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KIAA0101 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for KIAA0101 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for KIAA0101 gene:
    Search GeneIP for patents involving KIAA0101

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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