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Aliases for KIAA0100 Gene

Aliases for KIAA0100 Gene

  • KIAA0100 2 3
  • Breast Cancer-Overexpressed Gene 1 Protein 3 4
  • Breast Cancer Overexpressed Gene 1 2 3
  • Cancer/Testis Antigen 101 2 3
  • Antigen MLAA-22 3 4
  • BCOX1 3 4
  • U937-Associated Antigen 3
  • Protein KIAA0100 3
  • CT101 3
  • BCOX 3

External Ids for KIAA0100 Gene

Summaries for KIAA0100 Gene

GeneCards Summary for KIAA0100 Gene

KIAA0100 (KIAA0100) is a Protein Coding gene. Diseases associated with KIAA0100 include in situ carcinoma and breast cancer.

UniProtKB/Swiss-Prot for KIAA0100 Gene

  • May be involved in membrane trafficking.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA0100 Gene

Genomics for KIAA0100 Gene

Genomic Location for KIAA0100 Gene

Start:
28,614,440 bp from pter
End:
28,645,454 bp from pter
Size:
31,015 bases
Orientation:
Minus strand

Genomic View for KIAA0100 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA0100 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0100 Gene

Regulatory Elements for KIAA0100 Gene

Proteins for KIAA0100 Gene

  • Protein details for KIAA0100 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14667-K0100_HUMAN
    Recommended name:
    Protein KIAA0100
    Protein Accession:
    Q14667
    Secondary Accessions:
    • A6NCX3
    • Q3SYN5
    • Q49A07
    • Q5H9T4
    • Q6WG74
    • Q6ZP51
    • Q96HH8

    Protein attributes for KIAA0100 Gene

    Size:
    2235 amino acids
    Molecular mass:
    253700 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ93061.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=AAQ93061.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305}; Sequence=BAC85274.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA0100 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0100 Gene

Proteomics data for KIAA0100 Gene at MOPED

Post-translational modifications for KIAA0100 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Thr97 and Asn730

Other Protein References for KIAA0100 Gene

No data available for DME Specific Peptides for KIAA0100 Gene

Domains for KIAA0100 Gene

Protein Domains for KIAA0100 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KIAA0100 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q14667

UniProtKB/Swiss-Prot:

K0100_HUMAN
Family:
  • Belongs to the SABRE family.:
    • Q14667
genes like me logo Genes that share domains with KIAA0100: view

No data available for Gene Families for KIAA0100 Gene

Function for KIAA0100 Gene

Molecular function for KIAA0100 Gene

UniProtKB/Swiss-Prot Function: May be involved in membrane trafficking.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA0100 Gene

Localization for KIAA0100 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIAA0100 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA0100 Gene COMPARTMENTS Subcellular localization image for KIAA0100 gene
Compartment Confidence
extracellular 3
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for KIAA0100 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with KIAA0100: view

Pathways for KIAA0100 Gene

SuperPathways for KIAA0100 Gene

No Data Available

Interacting Proteins for KIAA0100 Gene

Selected Interacting proteins: Q14667-K0100_HUMAN for KIAA0100 Gene via I2D

Gene Ontology (GO) - Biological Process for KIAA0100 Gene

None

No data available for Pathways by source for KIAA0100 Gene

Transcripts for KIAA0100 Gene

Unigene Clusters for KIAA0100 Gene

KIAA0100:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0100 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19 ^ 20a · 20b ·
SP1: - - -
SP2: - -
SP3: - -
SP4:
SP5:
SP6: -
SP7:
SP8: -
SP9:
SP10: -
SP11:

ExUns: 20c ^ 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36a · 36b ^ 37 ^ 38 ^ 39 ^ 40
SP1:
SP2:
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:

Relevant External Links for KIAA0100 Gene

GeneLoc Exon Structure for
KIAA0100
ECgene alternative splicing isoforms for
KIAA0100

Expression for KIAA0100 Gene

mRNA expression in normal human tissues for KIAA0100 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for KIAA0100 Gene

SOURCE GeneReport for Unigene cluster for KIAA0100 Gene Hs.151761

mRNA Expression by UniProt/SwissProt for KIAA0100 Gene

Q14667-K0100_HUMAN
Tissue specificity: Expressed in pancreas, placenta and up-regulated in breast carcinoma epithelial cells, ductal in situ carcinoma (DCIS), invasive breast carcinoma (IBC) and metastatic breast carcinoma cells (MET).
genes like me logo Genes that share expressions with KIAA0100: view

No data available for mRNA differential expression in normal tissues for KIAA0100 Gene

Orthologs for KIAA0100 Gene

This gene was present in the common ancestor of animals.

Orthologs for KIAA0100 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0100 36
  • 99 (a)
OneToOne
LOC468197 35
  • 99.6 (n)
  • 99.7 (a)
cow
(Bos Taurus)
Mammalia KIAA0100 35
  • 91.01 (n)
  • 94.21 (a)
KIAA0100 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA0100 35
  • 91.46 (n)
  • 95.07 (a)
KIAA0100 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2610507B11Rik 35
  • 89.56 (n)
  • 94.53 (a)
2610507B11Rik 16
2610507B11Rik 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA0100 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0100 36
  • 87 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1307929 35
  • 89.14 (n)
  • 94.17 (a)
chicken
(Gallus gallus)
Aves KIAA0100 35
  • 75.54 (n)
  • 81.81 (a)
KIAA0100 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA0100 36
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0100 35
  • 68.26 (n)
  • 72.09 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-259g3.4 36
  • 65 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005472 35
  • 48.42 (n)
  • 37.15 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14967 35
  • 49.01 (n)
  • 38.62 (a)
CG14967 36
  • 30 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F31C3.3 35
  • 44.83 (n)
  • 33.69 (a)
F31C3.3 36
  • 28 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.10977 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
OneToOne
Species with no ortholog for KIAA0100:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KIAA0100 Gene

ENSEMBL:
Gene Tree for KIAA0100 (if available)
TreeFam:
Gene Tree for KIAA0100 (if available)

Paralogs for KIAA0100 Gene

No data available for Paralogs for KIAA0100 Gene

Variants for KIAA0100 Gene

Sequence variations from dbSNP and Humsavar for KIAA0100 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs520425 -- 28,632,603(-) ctgtg(A/T)cctaa intron-variant
rs550816 -- 28,640,944(-) aatga(G/T)gttta intron-variant
rs564159 -- 28,617,937(-) aaaaa(A/G)aaaaa intron-variant
rs588562 -- 28,626,854(-) AGGAC(C/T)GAAGG intron-variant
rs665835 -- 28,635,622(-) TTCTT(C/T)TGCTC intron-variant

Relevant External Links for KIAA0100 Gene

HapMap Linkage Disequilibrium report
KIAA0100
Human Gene Mutation Database (HGMD)
KIAA0100

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for KIAA0100 Gene

Disorders for KIAA0100 Gene

Relevant External Links for KIAA0100

Genetic Association Database (GAD)
KIAA0100
genes like me logo Genes that share disorders with KIAA0100: view

No data available for UniProtKB/Swiss-Prot for KIAA0100 Gene

Publications for KIAA0100 Gene

  1. Identification of BCOX1, a novel gene overexpressed in breast cancer. (PMID: 16289875) Song J. … Bai J. (Biochim. Biophys. Acta 2006) 2 3 4
  2. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 7788527) Nagase T. … Nomura N. (DNA Res. 1995) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for KIAA0100 Gene

Sources for KIAA0100 Gene

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