KHK Gene
protein-coding GIFtS: 60
GCID: GC02P027309
|
|
ketohexokinase (fructokinase)
| |
Aliases
for KHK gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ketohexokinase (Fructokinase)1 2 | | Hepatic Fructokinase2 3 | | Ketohexokinase1 | | EC 2.7.1.33 |
Export aliases for KHK gene to outside databasesPrevious GC identifers: GC02P027231 GC02P027402 GC02P027267 GC02P027284 GC02P027221 GC02P027051 |
Summaries
for KHK gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KHK:
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of thisgene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively splicedtranscript variants encoding different isoforms have been identified. (provided by RefSeq, Jul 2008)
|
Genomic Views
for KHK gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KHK gene promoter:
ER-alpha Pax-5 Meis-1b C/EBPalpha Arnt PPAR-alpha E2F-1 E2F Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KHK
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KHK |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p23.3 Ensembl cytogenetic band: 2p23.3 HGNC cytogenetic band: 2p23.3-p23.2KHK Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P027309: view genomic region
(about GC identifiers)
Start:
|
27,309,611 bp from pter |
End:
|
27,323,640 bp from pter |
Size:
|
14,030 bases |
Orientation:
|
plus strand |
|
Proteins
for KHK gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KHK_HUMAN, P50053 (See
protein sequence)Recommended Name: Ketohexokinase Size: 298 amino acids; 32730 Da
Subunit: Homodimer
6/13 PDB 3D structures from  and Proteopedia  for KHK (see all 13):2HLZ (3D)
2HQQ (3D)
2HW1 (3D)
3B3L (3D)
3NBV (3D)
3NBW (3D)
Secondary accessions: Q6IBK2 Q99532 Q9BRJ3 Q9UMN1Alternative splicing: 2 isoforms: P50053-1 P50053-2 (More widely distributed but with a low expression level)Explore the universe of human proteins at neXtProt for KHK: NX_P50053
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P50053
KHK Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_000212.1 NP_006479.1
ENSEMBL proteins: ENSP00000260599 ENSP00000260598 ENSP00000404741 Reactome Protein details: P50053
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
KHK for ontologies About GeneDecksing
KHK Antibody Products:
Assay Products for KHK: |
Protein
Domains /
Families
for KHK gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KHK for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P50053ProtoNet protein and cluster: P50053 1 Blocks protein family: IPB002173 Carbohydrate kinase
UniProtKB/Swiss-Prot: KHK_HUMAN, P50053Similarity: Belongs to the carbohydrate kinase PfkB family |
Function
for KHK gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KHK_HUMAN, P50053Catalytic activity: ATP + D-fructose = ADP + D-fructose 1-phosphateEnzyme regulation: Requires potassium. Inhibition by ADP Genatlas biochemistry entry for KHK:ketohexokinase,fructose metabolism,energy pathway,expressed in liver,renal cortex and small intestine
Enzyme Number (IUBMB): EC 2.7.1.31
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KHK (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KHK (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): KHK (NM_000221) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KHK | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KHK |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KHK |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004454 | ketohexokinase activity |
IEA | -- | | GO:0005524 | ATP binding |
IEA | -- |
KHK for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for KHK:
Animal Models:
4 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Khk):
KHK for phenotypes About GeneDecksing
|
Pathways & Interactions
for KHK gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Fructose catabolism | | | 2 | Metabolism | | | 3 | Fructose and mannose metabolism | | | 4 | MPS IIIC - Sanfilippo syndrome C | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for KHK
3 
Reactome Pathways for KHK
2 
Kegg Pathways (Kegg details for KHK):
UniProtKB/Swiss-Prot: KHK_HUMAN, P50053Pathway: Carbohydrate metabolism; fructose metabolism
KHK for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KHK
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/29 Interacting proteins for KHK (P500531, 3 ENSP000002605984) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ARRB1 | P494071, 3, ENSP000003771414 | EBI-1053974,EBI-743313 I2D:
score=2 STRING: ENSP00000377141 | | DEDD | O756181, 3, ENSP000003569854 | EBI-1053974,EBI-1043164 I2D:
score=2 STRING: ENSP00000356985 | | LYZ | P616261, 3, ENSP000002612674 | EBI-1053974,EBI-355360 I2D:
score=2 STRING: ENSP00000261267 | | RNPS1 | Q152871, 3 | EBI-1053974,EBI-395959 I2D:
score=2 | | LCN1 | P310251, 3, ENSP000002635984 | EBI-1053974,EBI-1052433 I2D:
score=2 STRING: ENSP00000263598 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005975 | carbohydrate metabolic process |
TAS | -- | | GO:0006000 | fructose metabolic process |
-- | -- | | GO:0006001 | fructose catabolic process |
TAS | -- | | GO:0009744 | response to sucrose stimulus |
-- | -- | | GO:0009749 | response to glucose stimulus |
-- | -- |
KHK for ontologies About GeneDecksing
|
Drugs & Compounds
for KHK gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KHK for compounds About GeneDecksing
 Browse Tocris compounds for KHK
5 HMDB Compounds for KHK About this table
3 Novoseek chemical compound relationships for KHK gene About this table
Search CenterWatch for drugs/clinical trials and news about KHK
|
Transcripts
for KHK gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KHK gene (2 alternative transcripts): NM_000221.2 NM_006488.2 Unigene Cluster for KHK: Ketohexokinase (fructokinase) Hs.567297 [show with all ESTs]Unigene Representative Sequence: NM_0002216 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000260599(uc002ril.2 uc002rio.2) ENST00000260598(uc002rim.2)
ENST00000490823 ENST00000429697 ENST00000469936 ENST00000464371
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KHK (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KHK (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): KHK (NM_000221) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KHK | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KHK |
Additional cDNA sequence: AK130033.1 AK223075.1 BC006233.2 BX648873.1 CR456801.1 X78677.1 X78678.1 7 DOTS entries: DT.447396 DT.97794122 DT.100839952 DT.95104826 DT.97851257 DT.95104793 DT.95104795 24/168 AceView cDNA sequences (see all 168): BQ893175 CR617023 CR622392 CR610051 NM_006488 BM695404 CR612248 CR591043 CB139063 CB141195 CB137744 CB148348 BM923935 CR618568 CB146948 CB164078 NM_000221 CB134880 CB154910 CB138530 CR604516 CR625259 CB137667 CR622479
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KHK (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KHK
|
Expression
for KHK gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KHK expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See KHK Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KHK
SOURCE GeneReport for Unigene cluster: Hs.567297
UniProtKB/Swiss-Prot: KHK_HUMAN, P50053Tissue specificity: Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle,brain and eye
SABiosciences Expression via Pathway-Focused PCR Array including KHK: | Molecular Toxicology PathwayFinder 384HT in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KHK
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KHK |
Orthologs
for KHK gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KHK gene from 4/17 species (see all 17) About this table
ENSEMBL Gene Tree for KHK (if available)
TreeFam Gene Tree for KHK (if available) |
Paralogs
for KHK gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KHK gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KHK (27309611 - 27323640 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KHK
1 CNV: 9399
Human Gene Mutation Database (HGMD): KHK
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KHK |
|
Disorders
/ Diseases
for KHK gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KHK for disorders About GeneDecksing
OMIM gene information: 614058
OMIM disorders: --
UniProtKB/Swiss-Prot: KHK_HUMAN, P50053
Defects in KHK are the cause of fructosuria (FRUCT) [MIM:229800]. Benign defect of intermediary metabolism
11  diseases for KHK: About MalaCardshepatitis renal clear cell carcinoma obstructive jaundice fatty liver disease
jaundice liver disease renal cell carcinoma hepatitis c
hepatocellular carcinoma carcinoma alcoholism
3 Novoseek disease relationships for KHK gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| carcinoma renal cell |
27.3 |
1 |
16372272 (1) |
| tumors |
0 |
2 |
16372272 (2) |
| cancer |
0 |
1 |
16372272 (1) |
Genatlas disease: KHK fructosuria
Human Genome Epidemiology (HuGE) Navigator: KHK (3 documents)
Export disorders for KHK gene to outside databases
|
Publications
for KHK gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KHK gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with KHK) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular basis of essential fructosuria: molecular cloning and mutational analysis of human ketohexokinase (fructokinase). (PubMed id 7833921)1, 2, 3, 9 Bonthron D.T.... Steinmann B. (1994)
- Structures of alternatively spliced isoforms of human ketohexokinase. (PubMed id 19237742)1, 2, 9 Trinh C.H....Phillips S.E. (2009)
- Structure and alternative splicing of the ketohexokinase gene. (PubMed id 9799106)1, 2, 9 Hayward B.E. and Bonthron D.T. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Co-localization of the ketohexokinase and glucokinase regulator genes to a 500-kb region of chromosome 2p23. (PubMed id 8662230)1, 9 Hayward B.E....Bonthron D.T. (1996)
- The expression of ketohexokinase is diminished in human clear cell type of renal cell carcinoma. (PubMed id 16372272)1, 9 Hwa J.S....Kang K.R. (2006)
- Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. (PubMed id 19158351)1, 9 Cirillo P....Sautin Y.Y. (2009)
- Properties of normal and mutant recombinant human ketohexokinases and implications for the pathogenesis of essential fructosuria. (PubMed id 12941785)1, 9 Asipu A....Bonthron D.T. (2003)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for KHK gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KHK gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KHK gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KHK gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KHK | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KHK gene:
Search GeneIP for patents involving KHK
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KHK gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for KHK | | OriGene shRNA RFP for KHK | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KHK | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KHK | | | OriGene Protein Over-expression Lysate for KHK | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KHK | | OriGene 3'-UTR Clone for KHK | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KHK | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KHK | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KHK | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KHK | | OriGene Custom Protein Services for KHK | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KHK | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KHK | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KHK | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KHK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KHK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KHK |
| |
 |  |  |  | |
| | | | Search Tocris compounds for KHK |
| |  |  |  |  | | | | | | Recombinant Protein for KHK |
|
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 |
 |
 | | | KHK Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KHK |
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