Aliases for KHK Gene
External Ids for KHK Gene
Previous GeneCards Identifiers for KHK Gene
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for KHK Gene
KHK (Ketohexokinase) is a Protein Coding gene. Diseases associated with KHK include Fructosuria, Essential and Fructose-1,6-Bisphosphatase Deficiency. Among its related pathways are Fructose metabolism and Uric Acid-Lowering Drugs Pathway, Pharmacodynamics. GO annotations related to this gene include fructokinase activity and ketohexokinase activity.
UniProtKB/Swiss-Prot for KHK Gene
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.