Aliases for KHDRBS2 Gene
External Ids for KHDRBS2 Gene
Previous GeneCards Identifiers for KHDRBS2 Gene
GeneCards Summary for KHDRBS2 Gene
KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2) is a Protein Coding gene. Among its related pathways are Signaling by PTK6 and Signaling by GPCR. GO annotations related to this gene include nucleic acid binding and protein heterodimerization activity. An important paralog of this gene is KHDRBS1.
UniProtKB/Swiss-Prot for KHDRBS2 Gene
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).