KGFLP1 Gene
pseudogene GIFtS: 29
GCID: GC09P046688
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KGFLP1
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Aliases
for KGFLP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 2
| Aliases |
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| Fibroblast Growth Factor 7 Pseudogene2 | | KGF-Like Protein 13 |
| External Ids: | Entrez Gene: 3876282 | Ensembl: ENSG000002274497 | UniProtKB: Q2TVT43 | | ORGUL members: | |
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| NONCODE:n387699 | |
Export aliases for KGFLP1 gene to outside databasesPrevious GC identifers: GC09P065012 GC09P046527
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Summaries
for KGFLP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KGFLP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_086755.3
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KGFLP1 gene promoter:
RelA Arnt POU2F1 FOXO4 POU2F1a HSF2 FOXO1a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KGFLP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KGFLP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p11.2 Ensembl cytogenetic band: 9p11.2 KGFLP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P046688: view genomic region
(about GC identifiers)
Start:
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46,687,462 bp from pter |
End:
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46,748,386 bp from pter |
Size:
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60,925 bases |
Orientation:
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plus strand |
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Proteins
for KGFLP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KGFL1_HUMAN, Q2TVT4 (See
protein sequence)Recommended Name: Putative keratinocyte growth factor-like protein 1 Size: 97 amino acids; 11079 Da
Caution: Could be the product of a pseudogene. Highly similar to the C-terminus of FGF7 but lacks the N-terminal part.As it has lost it signal peptide it is unlikely to be active. Maps to a duplicated region on chromosome 9Explore the universe of human proteins at neXtProt for KGFLP1: NX_Q2TVT4
KGFLP1 Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products:
KGFLP1 Antibody Products:
Assay Products for KGFLP1: |
Protein
Domains /
Families
for KGFLP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KGFLP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q2TVT4ProtoNet protein and cluster: Q2TVT4 1 Blocks protein family: IPB002348 IL1/HBGF family signature
UniProtKB/Swiss-Prot: KGFL1_HUMAN, Q2TVT4Similarity: Belongs to the heparin-binding growth factors family |
Function
for KGFLP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KGFLP1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008083 | growth factor activity |
IEA | -- |
KGFLP1 for ontologies About GeneDecksing
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Pathways & Interactions
for KGFLP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KGFLP1
|
Drugs & Compounds
for KGFLP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KGFLP1
Search CenterWatch for drugs/clinical trials and news about KGFLP1 
|
Transcripts
for KGFLP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KGFLP1 gene: NM_174950.2 Unigene Cluster for KGFLP1: Fibroblast growth factor 7 pseudogene Hs.439341 [show with all ESTs]Unigene Representative Sequence: AY0985933 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377614(uc011lrd.2) ENST00000452826 ENST00000451282
Additional cDNA sequence: AF523265.1 AK307215.1 AY098593.1 BC101842.1 BC112977.1 BC112978.1 NR_003674.2 NR_047527.1 11 DOTS entries: DT.92426456 DT.110426 DT.121159705 DT.121207073 DT.121212171 DT.121212214 DT.121212304 DT.95115743 DT.97776272 DT.99939955 DT.99955001 24/31 AceView cDNA sequences (see all 31): AW168170 NM_174950 AF523265 BG426408 BV167881 BM728755 AK054997 BI768457 BV167955 BM925376 BG188472 AI244161 BV198487 BG190094 AW291998 BX390829 BI047259 BX509336 BI914008 BX492480 BC030269 BG708001 BG699277 BI552868
GeneLoc Exon Structure
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Expression
for KGFLP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KGFLP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTTTTCCT
About this image
Genevestigator expression for KGFLP1
SOURCE GeneReport for Unigene cluster: Hs.439341
SABiosciences Custom PCR Arrays for KGFLP1
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KGFLP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat KGFLP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KGFLP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KGFLP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KGFLP1 |
Orthologs
for KGFLP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for KGFLP1 (if available)
TreeFam Gene Tree for KGFLP1 (if available) |
Paralogs
for KGFLP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for KGFLP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for KGFLP1 (46687462 - 46748386 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for KGFLP1
9 CNVs: 31497 70664 70663 59535 31498 70665 96069 3769 83026
1 Indel: 33891 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for KGFLP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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KGFLP1 for disorders About GeneDecksing
1  disease for KGFLP1: About MalaCardsovarian cancer
Export disorders for KGFLP1 gene to outside databases
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Publications
for KGFLP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for KGFLP1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KGFLP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- FGF7-like gene is associated with pericentric inversion of chromosome 9, and FGF7 is involved in the development of ovarian cancer. (PubMed id 15809711)1, 2 Yasuhara T.... Ohtake Y. (2005)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for KGFLP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KGFLP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing KGFLP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KGFLP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for KGFLP1 gene:
Search GeneIP for patents involving KGFLP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KGFLP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KGFLP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KGFLP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KGFLP1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KGFLP1 | | Browse OriGene Myc/DDK tagged cDNA clones in CMV expression vector | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KGFLP1 | | OriGene Custom Protein Services for KGFLP1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KGFLP1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KGFLP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KGFLP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KGFLP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KGFLP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KGFLP1 |
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 |  |  |  | |
| | | | Search Tocris compounds for KGFLP1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KGFLP1 |
|  |  |  | | | | Search ThermoFisher Antibodies for KGFLP1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KGFLP1 |
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Last full update: 19 Mar 2013 -
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