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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KDM8 Gene

protein-coding   GIFtS: 44
GCID: GC16P027214

Lysine (K)-Specific Demethylase 8

(Previous name: jumonji domain containing 5)
(Previous symbol: JMJD5)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Lysine (K)-Specific Demethylase 81 2     Jumonji Domain-Containing Protein 52 3
JMJD51 2 3 5     Lysine-Specific Demethylase 82
Jumonji Domain Containing 51 2     EC 1.14.11.273
JmjC Domain-Containing Protein 52 3     

External Ids:    HGNC: 258401   Entrez Gene: 798312   Ensembl: ENSG000001556667   OMIM: 6119175   UniProtKB: Q8N3713   

Export aliases for KDM8 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KDM8 Gene:
This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential
role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been
described.(provided by RefSeq, Feb 2009)

GeneCards Summary for KDM8 Gene: 
KDM8 (lysine (K)-specific demethylase 8) is a protein-coding gene. Diseases associated with KDM8 include pandas, and breast cancer. GO annotations related to this gene include chromatin binding and histone demethylase activity (H3-K36 specific). An important paralog of this gene is TYW5.

UniProtKB/Swiss-Prot: KDM8_HUMAN, Q8N371
Function: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates
dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription
activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010393.16  NC_018927.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for KDM8
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKDM8 promoter sequence
   Search SABiosciences Chromatin IP Primers for KDM8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDM8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.1   Ensembl cytogenetic band:  16p12.1   HGNC cytogenetic band: 16p12.1

KDM8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KDM8 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P027214:  view genomic region     (about GC identifiers)

Start:
27,214,807 bp from pter      End:
27,233,089 bp from pter
Size:
18,283 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KDM8_HUMAN, Q8N371 (See protein sequence)
Recommended Name: Lysine-specific demethylase 8  
Size: 416 amino acids; 47270 Da
Cofactor: Binds 1 Fe(2+) ion per subunit (By similarity)
Subcellular location: Nucleus
4 PDB 3D structures from and Proteopedia for KDM8:
3UYJ (3D)        4AAP (3D)        4GJY (3D)        4GJZ (3D)    
Secondary accessions: B4DLU9 Q6VAK5 Q9H8B1
Alternative splicing: 3 isoforms:  Q8N371-1   Q8N371-2   Q8N371-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KDM8: NX_Q8N371

Explore proteomics data for KDM8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N371

  • KDM8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KDM8 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001138820.1  NP_079049.2  

    ENSEMBL proteins: 
     ENSP00000286096   ENSP00000456107   ENSP00000398410   ENSP00000454215   ENSP00000456901  
     ENSP00000455463   ENSP00000370335  

    Human Recombinant Protein Products for KDM8: 
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    Novus Biologicals KDM8 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--

    KDM8 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    KDM: Chromatin-modifying enzymes / K-demethylases

    1 InterPro protein domain:
     IPR003347 JmjC_dom

    Graphical View of Domain Structure for InterPro Entry Q8N371

    ProtoNet protein and cluster: Q8N371

    UniProtKB/Swiss-Prot: KDM8_HUMAN, Q8N371
    Similarity: Contains 1 JmjC domain


    KDM8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KDM8_HUMAN, Q8N371
    Function: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates
    dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription
    activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation
    Catalytic activity: Protein N(6),N(6)-dimethyl-L-lysine + 2-oxoglutarate + O(2) = protein N(6)-methyl-L-lysine +
    succinate + formaldehyde + CO(2)
    Catalytic activity: Protein N(6)-methyl-L-lysine + 2-oxoglutarate + O(2) = protein L-lysine + succinate +
    formaldehyde + CO(2)

         Enzyme Number (IUBMB): EC 1.14.11.271

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding IDA--
    GO:0005515protein binding ----
    GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ----
    GO:0046872metal ion binding IEA--
    GO:0051864histone demethylase activity (H3-K36 specific) IDA--
         
    KDM8 for ontologies           About GeneDecksing


    Phenotypes:
         14 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Kdm8):
     behavior/neurological  cardiovascular system  cellular  embryogenesis  growth/size 
     hematopoietic system  homeostasis/metabolism  immune system  integument  mortality/aging 
     nervous system  normal  pigmentation  vision/eye 

    KDM8 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Kdm8tm1.2Tasu for KDM8

       inGenious Targeting Laboratory - Custom generated mouse model solutions for KDM8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KDM8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KDM8 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KDM8 

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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KDM8

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for KDM8 (Q8N3713 ENSP000003984104) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCYT2Q994473, ENSP000003317194I2D: score=4 STRING: ENSP00000331719
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle IMP--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0045893positive regulation of transcription, DNA-dependent IMP--
    GO:0070544histone H3-K36 demethylation IDA--

    KDM8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KDM8

    Search CenterWatch for drugs/clinical trials and news about KDM8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KDM8 gene (2 alternative transcripts): 
    NM_001145348.1  NM_024773.2  

    Unigene Cluster for KDM8:

    Lysine (K)-specific demethylase 8
    Hs.145717  [show with all ESTs]
    Unigene Representative Sequence: NM_001145348
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000286096(uc002doh.2 uc010vcn.1 uc010bxx.2) ENST00000564961(uc010bxv.2)
    ENST00000562269 ENST00000569329 ENST00000441782 ENST00000562733 ENST00000563881
    ENST00000568965 ENST00000563571 ENST00000567785 ENST00000567366 ENST00000568792
    ENST00000567735 ENST00000569592 ENST00000380948(uc010bxw.2)
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDM8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDM8

    Additional mRNA sequence: 

    AK023860.1 AK055679.1 AK225066.1 AK297166.1 AK298410.1 AK308499.1 AK310885.1 AY345239.1 
    BC027911.1 

    11 DOTS entries:

    DT.40305942  DT.102823164  DT.70104071  DT.100736450  DT.101978080  DT.75128004  DT.100664964  DT.100736452 
    DT.120661097  DT.95153259  DT.100725007 

    24/52 AceView cDNA sequences (see all 52):

    AK055679 BQ022832 BQ066794 BQ689669 BQ057705 CB160363 BP338003 CR608978 
    AW665036 AY345239 BM478152 AA383674 NM_024773 BM922658 AI288219 AI122764 
    BX283857 AL529811 BC027911 BM919718 BX329005 BI768810 BU430384 AU141170 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for KDM8 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b · 13c ·
    SP1:                                                                                                                                -                           
    SP2:                    -     -                       -                                                                                                         
    SP3:                                                                                                                          -     -     -                     
    SP4:                    -     -     -                                                                                                                           
    SP5:                    -     -     -                                   -     -                                                                                 

    ExUns: 13d
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for KDM8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KDM8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTCAAGGAT
    KDM8 Expression
    About this image


    See KDM8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KDM8

    SOURCE GeneReport for Unigene cluster: Hs.145717

    UniProtKB/Swiss-Prot: KDM8_HUMAN, Q8N371
    Tissue specificity: Weakly expressed in most cells. Highly expressed in breast cancer cells

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KDM8 gene from 8/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kdm85
    Jmjd51
    jumonji domain containing 51, 5 79.18(n)1
    78.45(a)1
      7 (68.85 cM)5
    770351  NM_029842.51  NP_084118.11 
     1254446765 
    chicken
    (Gallus gallus)
    Aves JMJD51 jumonji domain containing 5 66.33(n)
    63.27(a)
      416583  XM_414883.3  XP_414883.3 
    lizard
    (Anolis carolinensis)
    Reptilia KDM86
    Uncharacterized protein
    54(a)
    1 ↔ 1
    GL343612.1(162675-168042)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.168682 Transcribed sequence with weak similarity to protein more 77.99(n)    BI984262.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG139021 CG13902 52.35(n)
    42.64(a)
      38097  NM_138219.2  NP_612063.2 
    worm
    (Caenorhabditis elegans)
    Secernentea jmjd-51 Protein JMJD-5 46.25(n)
    37.36(a)
      179543  NM_073430.2  NP_505831.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G208101 transcription factor jumonji (jmjC) domain-containing more 49.32(n)
    43.6(a)
      821629  NM_180286.1  NP_850617.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g04892001 hypothetical protein 52.34(n)
    45.73(a)
      4347435  NM_001070068.2  NP_001063533.2 


    ENSEMBL Gene Tree for KDM8 (if available)
    TreeFam Gene Tree for KDM8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KDM8 gene
    TYW52  HSPBAP12  HIF1AN2  

    KDM8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/458 SNPs in KDM8 are shown (see all 458)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1891440491,2
    --27212871(+) ACGGAC/GTCTCG 1 -- us2k10--------
    rs1815528081,2
    --27212924(+) AGCTCC/TGCCTC 1 -- us2k10--------
    rs1842814161,2
    C--27213055(+) GGATGA/GTCTCA 1 -- us2k10--------
    rs80492041,2
    C,F,A,H--27213081(+) gatccG/Acccgc 1 -- us2k16Minor allele frequency- A:0.43NA 14
    rs1898399431,2
    --27213084(+) CCGCCC/TGCCTC 1 -- us2k10--------
    rs1472766241,2
    --27213129(+) CACCAC/TGCCTG 1 -- us2k10--------
    rs1487063301,2
    --27213222(+) CTTTTC/GTTTCA 1 -- us2k10--------
    rs71904531,2
    C,F--27213359(+) ccaggC/Gccagg 2 -- us2k11Minor allele frequency- G:0.05WA 118
    rs560623261,2
    C,F--27213581(+) GGGGTG/AGGGGG 2 -- us2k11Minor allele frequency- A:0.08NA 120
    rs1811208801,2
    --27213654(+) TTTTCC/TGGGGA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for KDM8 (27214807 - 27233089 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KDM8: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KDM8
    DNA2.0 Custom Variant and Variant Library Synthesis for KDM8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611917    OMIM disorders: --

    2 diseases for KDM8:    About MalaCards
    pandas    breast cancer


    KDM8 for disorders           About GeneDecksing


    Export disorders for KDM8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KDM8 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with KDM8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. (PubMed id 20457893)1, 2, 3 Hsia D.A....Izumiya Y. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Crystal structure and functional analysis of JMJD5 ind icate an alternate specificity and function. (PubMed id 22851697)1 Del Rizzo P.A....Trievel R.C. (2012)
    4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    5. JMJD5, a Jumonji C (JmjC) domain-containing protein, n egatively regulates osteoclastogenesis by facilitating NFATc1 protein degradatio n. (PubMed id 22375008)1 Youn M.Y....Imai Y. (2012)
    6. Jumonji domain protein JMJD5 functions in both the pl ant and human circadian systems. (PubMed id 21115819)1 Jones M.A....Harmer S.L. (2010)
    7. Histone lysine demethylases: emerging roles in development, physiology and disease. (PubMed id 17909537)1 Shi Y. (2007)
    8. Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice. (PubMed id 16858412)1 Suzuki T....Copeland N.G. (2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79831 HGNC: 25840 AceView: FLJ13798 Ensembl:ENSG00000155666 euGenes: HUgn79831
    ECgene: KDM8 H-InvDB: KDM8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KDM8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KDM8 gene:
    Search GeneIP for patents involving KDM8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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