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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KDM6B Gene

protein-coding   GIFtS: 52
GCID: GC17P007686

lysine (K)-specific demethylase 6B

(Previous names: jumonji domain containing 3, jumonji domain containing...)
(Previous symbol: JMJD3)
 Explore 4 diseases affiliated with
KDM6B via our new
 Human Malady Compendium 
Biological research products
for KDM6B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Lysine (K)-Specific Demethylase 6B1 2     Lysine Demethylase 6B2 3
JMJD31 2 3 5     Jumonji Domain Containing 31
KIAA03461 3 5     Lysine-Specific Demethylase 6B2
Jumonji Domain Containing 3, Histone Lysine Demethylase1 2     EC 1.14.11.-3
JmjC Domain-Containing Protein 32 3     EC 1.14.118
Jumonji Domain-Containing Protein 32 3     

External Ids:    HGNC: 290121   Entrez Gene: 231352   Ensembl: ENSG000001325107   OMIM: 6115775   UniProtKB: O150543   

Export aliases for KDM6B gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: KDM6B_HUMAN, O15054
Function: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in
histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior
development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage
differentiation in case of inflammation by regulating gene expression and macrophage differentiation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KDM6B gene promoter:
         Pax-6   Olf-1   XBP-1   HNF-4alpha2   Nkx2-5   NF-kappaB   LCR-F1   HNF-4alpha1   c-Ets-1   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for KDM6B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDM6B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

KDM6B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KDM6B gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P007686:  view genomic region     (about GC identifiers)

Start:
7,743,222 bp from pter      End:
7,758,118 bp from pter
Size:
14,897 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KDM6B_HUMAN, O15054 (See protein sequence)
Recommended Name: Lysine-specific demethylase 6B  
Size: 1643 amino acids; 176632 Da
Cofactor: Ascorbate (By similarity)
Cofactor: Fe(2+)
Subunit: Interacts with TLE1 (By similarity). Component of the MLL4 complex, at least composed of MLL4, ASH2L, RBBP5,
WDR5, and KDM6B
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAA21572.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
3 PDB 3D structures from and Proteopedia for KDM6B:
2XUE (3D)        2XXZ (3D)        4ASK (3D)    
Secondary accessions: C9IZ40 Q96G33
Alternative splicing: 2 isoforms:  O15054-2   O15054-1   (Gene prediction based on similarity to mouse ortholog)

Explore the universe of human proteins at neXtProt for KDM6B: NX_O15054

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O15054

  • 4/5 DME Specific Peptides for KDM6B (O15054) (see all 5)
     IKFGTNIDLSD  KLNPPTPSIYLE  SHTTIAKYAQYQA  GWCNNIAWNVGPLTA 

    KDM6B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001073893.1  
    ENSEMBL proteins: 
     ENSP00000254846   ENSP00000412513   ENSP00000458445  

    Human Recombinant Protein Products: 
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for KDM6B

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    KDM6B for ontologies           About GeneDecksing



    KDM6B Antibody Products: 
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    Uscn ELISAs and CLIAs for KDM6B


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    KDM6B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR003347 JmjC_dom

    Graphical View of Domain Structure for InterPro Entry O15054

    ProtoNet protein and cluster: O15054

    1 Blocks protein family: IPB003347 Transcription factor jumonji

    UniProtKB/Swiss-Prot: KDM6B_HUMAN, O15054
    Similarity: Belongs to the UTX family
    Similarity: Contains 1 JmjC domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: KDM6B_HUMAN, O15054
    Function: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in
    histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior
    development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage
    differentiation in case of inflammation by regulating gene expression and macrophage differentiation
    Induction: By 12-O-tetradecanoylphorbol-13-acetate (TPA) in myeloid leukemia cells

    Enzyme Numbers (IUBMB): EC 1.14.11.-1 EC 1.14.112

    miRNA
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    hsa-miR-3607-3p hsa-miR-3194-5p hsa-miR-106a hsa-miR-146a hsa-miR-1260b hsa-miR-30d hsa-miR-342-3p hsa-miR-519a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM6B

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA--
    GO:0043565sequence-specific DNA binding IEA--
    GO:0046872metal ion binding IEA--


    KDM6B for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for KDM6B:
     Small cells 

    Animal Models:
         Mouse knock-out Kdm6btm1Aki for KDM6B
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Kdm6b):
     immune system  mortality/aging  no phenotypic analysis  respiratory system 

    KDM6B for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Chromatin Regulation / Acetylation
    Chromatin Regulation / Acetylation1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for KDM6B
        Chromatin Regulation / Acetylation



    KDM6B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KDM6B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/22 Interacting proteins for KDM6B (O150542, 3 ENSP000002548464) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H3AP684313, ENSP000003502754I2D: score=1 STRING: ENSP00000350275
    HIST1H3BP684313I2D: score=1 
    HIST1H3CP684313I2D: score=1 
    HIST1H3DP684313I2D: score=1 
    HIST1H3EP684313I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006954inflammatory response IEA--
    GO:0016577histone demethylation IEA--


    KDM6B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KDM6B
    Search CenterWatch for drugs/clinical trials and news about KDM6B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KDM6B gene: 
    NM_001080424.1  

    Unigene Cluster for KDM6B:

    Lysine (K)-specific demethylase 6B
    Hs.223678  [show with all ESTs]
    Unigene Representative Sequence: NM_001080424
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000571047 ENST00000254846(uc002giw.1 uc002gix.3) ENST00000448097
    ENST00000572030 ENST00000575521 ENST00000570632

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    8/101 QIAGEN miScript miRNA Assays for microRNAs that regulate KDM6B (see all 101):
    hsa-miR-3607-3p hsa-miR-3194-5p hsa-miR-106a hsa-miR-146a hsa-miR-1260b hsa-miR-30d hsa-miR-342-3p hsa-miR-519a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Additional cDNA sequence: 

    AB002344.2 BC009994.1 BC035897.1 BC067879.1 

    8 DOTS entries:

    DT.85105311  DT.95162298  DT.120930861  DT.410301  DT.100689210  DT.100673297  DT.100696592  DT.95114142 

    24/255 AceView cDNA sequences (see all 255):

    CF529968 CB154770 AW952285 AA991279 BI092918 CD365458 NM_203411 BM849688 
    AI151324 AU149978 AI671664 BC057812 BU734395 AA355717 AW293774 BQ649062 
    BC035897 BG222892 BQ063399 BE467057 BQ012561 BQ015649 BQ721168 CR597798 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for KDM6B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20a · 20b
    SP1:                                                                                      -                                                         
    SP2:                                                                                                                                                
    SP3:                                                                                                                                                
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for KDM6B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KDM6B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGCTCAAAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See KDM6B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KDM6B

    SOURCE GeneReport for Unigene cluster: Hs.223678
        SABiosciences Expression via Pathway-Focused PCR Array including KDM6B: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM6B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KDM6B gene from 4/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia KDM6B6
    --
    51(a)
    1 ↔ 1
    GL343784.1(158025-188486)
    zebrafish
    (Danio rerio)
    Actinopterygii BX005336.46
    kdm6bb6
    lysine (K)-specific demethylase 6B, b
    32(a)
    30(a)
    1 ↔ many
    1 ↔ many
    7(22933203-22946812)
    10(22924269-22963924)
    fruit fly
    (Drosophila melanogaster)
    Insecta Utx6
    --
    29(a)
    1 → many
    2L(10272325-10278811)
    worm
    (Caenorhabditis elegans)
    Secernentea utx-16
    jmjd-3.36
    (see all 4)
    Protein JMJD-3.3
    (see all 4)
    21(a)
    20(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    X(8557099-8563186)
    X(13436386-13440943)


    ENSEMBL Gene Tree for KDM6B (if available)
    TreeFam Gene Tree for KDM6B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KDM6B gene
    UTY2  KDM6A2  
    5 SIMAP similar genes for KDM6B using alignment to 2 protein entries:     KDM6B_HUMAN (see all proteins):
    DKFZp686A03225    UTY    KDM6A    UTX    DKFZp451J023

    KDM6B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/381 NCBI SNPs in KDM6B are shown (see all 381    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1113368201,2
    --7741404(+) TGATTC/TTGAAG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs126011291,2
    H--7741763(+) CCCCCA/CCCCAC 1 -- us2k1 tfbs3 trp30--------
    rs126011301,2
    C,H--7741765(+) CCCCCA/CCACAC 1 -- us2k1 tfbs3 trp30--------
    rs1919075071,2
    --7741914(+) CACCCC/GTCACA 1 -- us2k10--------
    rs1436512221,2
    --7741993(+) CTCTCG/TACTAG 1 -- us2k10--------
    rs1510225831,2
    --7742070(+) TCTCTA/GCTCCC 1 -- us2k10--------
    rs1829319671,2
    --7742260(+) CTTGCA/GGAACA 1 -- us2k10--------
    rs2018095451,2
    --7742276(+) CATGG-/AGAC  
            
    AGACT
    1 -- us2k10--------
    rs1408749381,2
    --7742287(+) GGGGGC/TTAGAG 1 -- us2k10--------
    rs1448470331,2
    --7742445(+) GAGGTA/GAGGGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KDM6B (7743222 - 7758118 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for KDM6B: --
    Human Gene Mutation Database (HGMD): KDM6B

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    KDM6B for disorders           About GeneDecksing

    OMIM gene information: 611577    OMIM disorders: --

    4 diseases for KDM6B:    About MalaCards
    wiskott-aldrich syndrome    hodgkin's lymphoma    myeloid leukemia    leukemia


    Export disorders for KDM6B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KDM6B gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with KDM6B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
    2. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. (PubMed id 18003914)1, 2 Hong S....Ge K. (2007)
    3. Physical map of 17p13 and the genes adjacent to p53. (PubMed id 10662545)1, 3 Cousin P....Shaw P. (2000)
    4. ATF4-dependent regulation of the JMJD3 gene during ami no acid deprivation can be rescued in Atf4-deficient cells by inhibition of deac etylation. (PubMed id 22955275)1 Shan J....Kilberg M.S. (2012)
    5. Gene networking and inflammatory pathway analysis in a JMJD3 knockdown human monocytic cell line. (PubMed id 22252741)1 Das N.D....Chai Y.G. (2012)
    6. Histone demethylases KDM4B and KDM6B promotes osteogen ic differentiation of human MSCs. (PubMed id 22770241)1 Ye L....Wang C.Y. (2012)
    7. Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program. (PubMed id 22782721)1 Estaras C....Martinez-Balbas M.A. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Loss of the candidate tumor suppressor BTG3 triggers a cute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis. (PubMed id 22020331)1 Lin T.Y....Shieh S.Y. (2012)
    10. KSHV PAN RNA associates with demethylases UTX and JMJD 3 to activate lytic replication through a physical interaction with the virus ge nome. (PubMed id 22589717)1 Rossetto C.C. and Pari G. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23135 HGNC: 29012 AceView: FLJ32499andLOC92162andJMJD3 Ensembl:ENSG00000132510 euGenes: HUgn23135
    ECgene: KDM6B H-InvDB: KDM6B

    (According to HUGE)
    About This Section
    HUGE: KIAA0346

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KDM6B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KDM6B gene:
    Search GeneIP for patents involving KDM6B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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