Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KDM4E Gene

protein-coding   GIFtS: 28
GCID: GC11P094759

Lysine (K)-Specific Demethylase 4E

(Previous name: lysine (K)-specific demethylase 4D-like)
(Previous symbol: KDM4DL)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Lysine (K)-Specific Demethylase 4E1 2     JMJD2E2
KDM4DL1 2 3     Lysine-Specific Demethylase 4E2
KDM4D-Like Protein2 3     EC 1.14.11.-3
Lysine (K)-Specific Demethylase 4D-Like1     Lysine-Specific Demethylase 4D-Like3

External Ids:    HGNC: 370981   Entrez Gene: 3902452   Ensembl: ENSG000002352687   UniProtKB: B2RXH23   

Export aliases for KDM4E gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KDM4E Gene: 
KDM4E (lysine (K)-specific demethylase 4E) is a protein-coding gene. Diseases associated with KDM4E include retinoblastoma. GO annotations related to this gene include oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen and metal ion binding. An important paralog of this gene is KDM4D.

UniProtKB/Swiss-Prot: KDM4E_HUMAN, B2RXH2
Function: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role
in histone code




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_167190.1  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for KDM4E
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for KDM4E

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDM4E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q21   Ensembl cytogenetic band:  11q21   HGNC cytogenetic band: 11q21

KDM4E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KDM4E gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P094759:  view genomic region     (about GC identifiers)

Start:
94,758,422 bp from pter      End:
94,760,760 bp from pter
Size:
2,339 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KDM4E_HUMAN, B2RXH2 (See protein sequence)
Recommended Name: Lysine-specific demethylase 4E  
Size: 506 amino acids; 56804 Da
Cofactor: Binds 1 Fe(2+) ion per subunit
Subcellular location: Nucleus (By similarity)
1 PDB 3D structure from and Proteopedia for KDM4E:
2W2I (3D)    

Explore the universe of human proteins at neXtProt for KDM4E: NX_B2RXH2

Explore proteomics data for KDM4E at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_B2RXH2

  • KDM4E Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KDM4E Protein Expression
    REFSEQ proteins: NP_001155102.1  
    ENSEMBL proteins: 
     ENSP00000397239  

    Human Recombinant Protein Products for KDM4E: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for KDM4E
    GenScript Custom Purified and Recombinant Proteins Services for KDM4E
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    KDM4E for ontologies           About GeneDecksing



    KDM4E Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for KDM4E
    GenScript Custom Superior Antibodies Services for KDM4E
    Abcam antibodies for KDM4E
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for KDM4E
    Search LSBio for Antibodies for KDM4E 

    Assay Products for KDM4E: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KDM4E
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KDM4E
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    KDM: Chromatin-modifying enzymes / K-demethylases

    2 InterPro protein domains:
     IPR003347 JmjC_dom
     IPR003349 TF_JmjN

    Graphical View of Domain Structure for InterPro Entry B2RXH2

    ProtoNet protein and cluster: B2RXH2

    UniProtKB/Swiss-Prot: KDM4E_HUMAN, B2RXH2
    Similarity: Belongs to the JHDM3 histone demethylase family
    Similarity: Contains 1 JmjC domain
    Similarity: Contains 1 JmjN domain


    KDM4E for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KDM4E_HUMAN, B2RXH2
    Function: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role
    in histone code

         Enzyme Number (IUBMB): EC 1.14.11.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ----
    GO:0046872metal ion binding IEA--
    GO:0051213dioxygenase activity IEA--
         
    KDM4E for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KDM4E 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KDM4E

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KDM4E 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KDM4E 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KDM4E
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KDM4E
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KDM4E
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KDM4E

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KDM4E
    Sirion Biotech Customized adenovirus for overexpression of KDM4E

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for KDM4E (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for KDM4E
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KDM4E
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KDM4E
    Sirion Biotech Customized lentivirus for stable overexpression of KDM4E 
                         Customized lentivirus expression plasmids for stable overexpression of KDM4E 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KDM4E
    Search LifeMap BioReagents cell lines for KDM4E
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM4E


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KDM4E

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0016568chromatin modification IEA--

    KDM4E for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KDM4E

    Search CenterWatch for drugs/clinical trials and news about KDM4E

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KDM4E gene: 
    NM_001161630.1  

    Unigene Cluster for KDM4E:

    Lysine (K)-specific demethylase 4E
    Hs.714692
    Unigene Representative Sequence: BC157851
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000450979(uc010ruf.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KDM4E
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KDM4E
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KDM4E
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KDM4E
    Clone
    Products:
         
    OriGene clones in human, mouse for KDM4E (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for KDM4E
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KDM4E
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KDM4E
    Sirion Biotech Customized lentivirus for stable overexpression of KDM4E 
                         Customized lentivirus expression plasmids for stable overexpression of KDM4E 
    Primer
    Products:
        
    Browse OriGene qPCR
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat KDM4E
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDM4E
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDM4E

    Additional mRNA sequence: 

    BC157851.1 BC157889.1 BC171916.1 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section
    See probesets specificity/sensitivity at GeneAnnot
    CGAP TAG: --


    See KDM4E Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.714692
        SABiosciences Custom PCR Arrays for KDM4E
    Primer
    Products:
    Browse OriGene qPCR
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat KDM4E
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDM4E
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDM4E
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM4E

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for KDM4E gene from 3/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    rat
    (Rattus norvegicus)
    Mammalia Kdm4dl1 lysine (K)-specific demethylase 4D-like 75.86(n)
    72.13(a)
      500944  XM_576355.1  XP_576355.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Kdm4A6
    Kdm4B6
    Histone demethylase 4B
    37(a)
    27(a)
    many ↔ many
    many ↔ many
    2R(3810280-3812488)
    2R(9063599-9085869)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPH16
    GIS16
    JmjC domain-containing histone demethylase; specif...
    JmjC domain-containing histone demethylase and tra...
    17(a)
    12(a)
    many ↔ many
    many ↔ many
    V(523369-525759)
    IV(637139-639823)


    ENSEMBL Gene Tree for KDM4E (if available)
    TreeFam Gene Tree for KDM4E (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KDM4E gene
    KDM4D2  KDM4A2  KDM4C2  KDM4B2  
    5 SIMAP similar genes for KDM4E using alignment to 1 protein entry:     KDM4E_HUMAN:
    KDM4C    JMJD2B    KDM4A    KDM4B    KDM4D

    KDM4E for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for KDM4E
    PGOHUM00000242868 PGOHUM00000262572


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/133 SNPs in KDM4E are shown (see all 133)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1897653761,2
    --94756457(+) AAGGGA/GTGCAT 1 -- us2k10--------
    rs1831322671,2
    C--94756462(+) GTGCAA/TGATCG 1 -- us2k10--------
    rs1496365541,2
    C--94756536(+) GGATGC/TGAAGG 1 -- us2k10--------
    rs1144020991,2
    C,F--94756600(+) TAGTGA/CAGGAA 1 -- us2k11Minor allele frequency- C:0.05WA 118
    rs1891611561,2
    --94756609(+) AAGCAA/GATAAT 1 -- us2k10--------
    rs1928683841,2
    --94756630(+) TGTCTC/TGACCT 1 -- us2k10--------
    rs110210101,2
    C--94756972(+) TTTTTC/TGACAA 1 -- us2k14Minor allele frequency- T:0.33WA NA EA 360
    rs351177361,2
    C,F--94756994(+) GTCTCG/ATAGGA 1 -- us2k14Minor allele frequency- A:0.50NA CSA 8
    rs1392419961,2
    --94757021(+) GCCATC/TTTCTG 1 -- us2k10--------
    rs1838291911,2
    --94757028(+) TCTGGC/GCATTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KDM4E (94758422 - 94760760 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KDM4E: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KDM4E
    DNA2.0 Custom Variant and Variant Library Synthesis for KDM4E

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for KDM4E:    About MalaCards
    retinoblastoma    


    KDM4E for disorders           About GeneDecksing


    Export disorders for KDM4E gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KDM4E gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KDM4E)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Inhibition of the histone demethylase JMJD2E by 3-subs tituted pyridine 2,4-dicarboxylates. (PubMed id 21076780)1, 3 Thalhammer A....Schofield C.J. (2011)
    2. Investigations on the oxygen dependence of a 2-oxoglut arate histone demethylase. (PubMed id 23092293)1 Sanchez-Fernandez E.M....Flashman E. (2013)
    3. Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family. (PubMed id 21914792)2 Hillringhaus L.... Oppermann U. (2011)
    4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 390245 HGNC: 37098 Ensembl:ENSG00000235268 euGenes: HUgn390245 ECgene: KDM4E
    H-InvDB: KDM4E

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KDM4E Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KDM4E gene:
    Search GeneIP for patents involving KDM4E

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KDM4E  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for KDM4E  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KDM4E   OriGene Custom Protein Services for KDM4E  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KDM4E
     QIAGEN SeqTarget long-range PCR primers for resequencing KDM4E
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDM4E
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KDM4E
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDM4E
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDM4E
     GenScript Custom Purified and Recombinant Proteins Services for KDM4E GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for KDM4E
     GenScript Custom Assay Services for KDM4E GenScript Custom Superior Antibodies Services for KDM4E
     GenScript Custom overexpressing Cell Line Services for KDM4E CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for KDM4E
     Search Chromatin IP Primers for KDM4E
     Search RT2 qPCR Primer Assays in human, mouse, rat KDM4E
     Search GNC Networks for KDM4E
     SABiosciences Custom PCR Arrays for KDM4E
     Search Tocris compounds for KDM4E
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Antibodies for KDM4E
     See all of Abcam's Antibodies, Kits and Proteins for KDM4E
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for KDM4E
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM4E
     Browse SwitchGear 3'UTR luciferase reporter plasmids for KDM4E
     Browse SwitchGear Promoter luciferase reporter plasmids for KDM4E
     Search ThermoFisher Antibodies for KDM4E
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KDM4E
     inGenious Targeting Laboratory - Custom generated mouse model solutions for KDM4E
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KDM4E
    Customized:
     lentivirus for stable overexpression of KDM4E
     lentivirus expression plasmids for stable overexpression of KDM4E
     adenovirus for overexpression of KDM4E
     Search LSBio for Antibodies for KDM4E
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KDM4E gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4