Aliases for KDM4E Gene
External Ids for KDM4E Gene
Previous HGNC Symbols for KDM4E Gene
Previous GeneCards Identifiers for KDM4E Gene
The protein encoded by this intronless gene is a member of a large family of histone lysine demethylases, which use oxygen and 2-oxoglutarate to demethylate di- and trimethylated lys9 of histone H3. Derepression of genes by demethylases is sometimes involved in viral infection or carcinogenesis, so inhibitors of these enzymes are desired. [provided by RefSeq, Dec 2016]
GeneCards Summary for KDM4E Gene
KDM4E (Lysine Demethylase 4E) is a Protein Coding gene. GO annotations related to this gene include dioxygenase activity. An important paralog of this gene is KDM4D.
UniProtKB/Swiss-Prot for KDM4E Gene
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code.