Aliases for KDM4D Gene
External Ids for KDM4D Gene
Previous HGNC Symbols for KDM4D Gene
Previous GeneCards Identifiers for KDM4D Gene
GeneCards Summary for KDM4D Gene
KDM4D (Lysine (K)-Specific Demethylase 4D) is a Protein Coding gene. Among its related pathways are Chromatin organization and RNA Polymerase I Promoter Opening. GO annotations related to this gene include dioxygenase activity and histone demethylase activity (H3-K9 specific). An important paralog of this gene is KDM4B.
UniProtKB/Swiss-Prot for KDM4D Gene
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36 nor H4 Lys-20. Demethylates both di- and trimethylated H3 Lys-9 residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.