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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KDM4D Gene

protein-coding   GIFtS: 52
GCID: GC11P094706

Lysine (K)-Specific Demethylase 4D

(Previous name: jumonji domain containing 2D)
(Previous symbol: JMJD2D)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Lysine (K)-Specific Demethylase 4D1 2     Lysine-Specific Demethylase 4D2
JMJD2D1 2 3 5     EC 1.14.11.-3
Jumonji Domain Containing 2D1 2     JHDM3D3
JmjC Domain-Containing Histone Demethylation Protein 3D2 3     EC 1.14.118
Jumonji Domain-Containing Protein 2D2 3     

External Ids:    HGNC: 254981   Entrez Gene: 556932   Ensembl: ENSG000001862807   OMIM: 6097665   UniProtKB: Q6B0I63   

Export aliases for KDM4D gene to outside databases

Previous GC identifers: GC11P094347 GC11P090771


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KDM4D Gene: 
KDM4D (lysine (K)-specific demethylase 4D) is a protein-coding gene. Diseases associated with KDM4D include retinoblastoma. GO annotations related to this gene include oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen and metal ion binding. An important paralog of this gene is KDM4A.

UniProtKB/Swiss-Prot: KDM4D_HUMAN, Q6B0I6
Function: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role
in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates
both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation
of Lys residue generates formaldehyde and succinate

Gene Wiki entry for KDM4D (JMJD2D) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KDM4D gene promoter:
         Sp1   AP-1   RREB-1   Nkx2-2   ATF-2   Nkx2-5   POU6F1 (c2)   S8   c-Jun   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKDM4D promoter sequence
   Search SABiosciences Chromatin IP Primers for KDM4D

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDM4D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q21   Ensembl cytogenetic band:  11q21   HGNC cytogenetic band: 11q21

KDM4D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KDM4D gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P094706:  view genomic region     (about GC identifiers)

Start:
94,706,845 bp from pter      End:
94,732,682 bp from pter
Size:
25,838 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KDM4D_HUMAN, Q6B0I6 (See protein sequence)
Recommended Name: Lysine-specific demethylase 4D  
Size: 523 amino acids; 58603 Da
Cofactor: Binds 1 Fe(2+) ion per subunit (By similarity)
Subcellular location: Nucleus (By similarity)
Caution: It is uncertain whether Met-1 or Met-4 is the initiator
Sequence caution: Sequence=BAA91508.1; Type=Erroneous initiation;
4 PDB 3D structures from and Proteopedia for KDM4D:
3DXT (3D)        3DXU (3D)        4HON (3D)        4HOO (3D)    
Secondary accessions: B3KPC4 Q0VF39 Q9NT41 Q9NW76

Explore the universe of human proteins at neXtProt for KDM4D: NX_Q6B0I6

Explore proteomics data for KDM4D at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6B0I6

  • 4/5 DME Specific Peptides for KDM4D (Q6B0I6) (see all 5)
     YSINYLH  GEPKTWY  LERKYWKN  EDMDLYSIN 

    KDM4D Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KDM4D Protein Expression
    REFSEQ proteins: NP_060509.2  
    ENSEMBL proteins: 
     ENSP00000334181   ENSP00000460897  

    Human Recombinant Protein Products for KDM4D: 
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    Novus Biologicals KDM4D Protein
    Novus Biologicals KDM4D Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KDM4D 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    KDM4D for ontologies           About GeneDecksing



    KDM4D Antibody Products: 
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    Cloud-Clone Corp. ELISAs for KDM4D 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    KDM: Chromatin-modifying enzymes / K-demethylases

    2 InterPro protein domains:
     IPR003347 JmjC_dom
     IPR003349 TF_JmjN

    Graphical View of Domain Structure for InterPro Entry Q6B0I6

    ProtoNet protein and cluster: Q6B0I6

    1 Blocks protein domain: IPB003347 Transcription factor jumonji

    UniProtKB/Swiss-Prot: KDM4D_HUMAN, Q6B0I6
    Similarity: Belongs to the JHDM3 histone demethylase family
    Similarity: Contains 1 JmjC domain
    Similarity: Contains 1 JmjN domain


    KDM4D for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KDM4D_HUMAN, Q6B0I6
    Function: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role
    in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates
    both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation
    of Lys residue generates formaldehyde and succinate

         Enzyme Numbers (IUBMB): EC 1.14.11.-1 EC 1.14.112

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ----
    GO:0046872metal ion binding IEA--
    GO:0051213dioxygenase activity IEA--
         
    KDM4D for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KDM4D:
     Decreased p24 protein expressi 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Kdm4d):
     cellular  endocrine/exocrine gland  growth/size  pigmentation  reproductive system 
     vision/eye 

    KDM4D for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Kdm4dtm1Zuk for KDM4D

       inGenious Targeting Laboratory - Custom generated mouse model solutions for KDM4D 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KDM4D

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KDM4D 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate KDM4D:
    hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidKDM4D 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM4D


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KDM4D

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for KDM4D (Q6B0I63 ENSP000003341814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARP102753, ENSP000003638224I2D: score=1 STRING: ENSP00000363822
    TP53ENSP000002693054STRING: ENSP00000269305
    PPP1CCENSP000003350844STRING: ENSP00000335084
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0016568chromatin modification ----
    GO:0033169histone H3-K9 demethylation IEA--

    KDM4D for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KDM4D

    Search CenterWatch for drugs/clinical trials and news about KDM4D

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KDM4D gene: 
    NM_018039.2  

    Unigene Cluster for KDM4D:

    Lysine (K)-specific demethylase 4D
    Hs.503598  [show with all ESTs]
    Unigene Representative Sequence: NM_018039
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335080(uc001pfe.3) ENST00000536741
    miRNA
    Products:
         
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate KDM4D:
    hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidKDM4D 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for KDM4D
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                         Customized lentivirus expression plasmids for stable overexpression of KDM4D 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDM4D
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDM4D

    Additional mRNA sequence: 

    AK001113.1 AK056162.1 AL137545.1 BC031862.1 BC074739.2 BC119010.1 BC122858.1 

    1 DOTS entry:

    DT.106378 

    24/26 AceView cDNA sequences (see all 26):

    AW339850 BC074739 NM_018039 AA732856 AU149055 AW593120 AU120493 AK056162 
    AI467798 AK001113 BQ006169 AA234602 AL137545 BC031862 CA311555 AA236569 
    AA435771 AA758505 BG719158 BE719807 BE719813 AU153509 AI350395 BX283998 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KDM4D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAGTTTTCA
    KDM4D Expression
    About this image


    See KDM4D Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KDM4D

    SOURCE GeneReport for Unigene cluster: Hs.503598
        SABiosciences Custom PCR Arrays for KDM4D
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDM4D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for KDM4D gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kdm4d1 , 5 lysine (K)-specific demethylase 4D1, 5 75.23(n)1
    72.71(a)1
      9 (4.05 cM)5
    2446941  NM_173433.21  NP_775609.21 
     144625485 
    fruit fly
    (Drosophila melanogaster)
    Insecta Kdm4A6
    Kdm4B6
    Histone demethylase 4B
    40(a)
    28(a)
    many ↔ many
    many ↔ many
    2R(3810280-3812488)
    2R(9063599-9085869)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPH16
    GIS16
    JmjC domain-containing histone demethylase; specif...
    JmjC domain-containing histone demethylase and tra...
    17(a)
    12(a)
    many ↔ many
    many ↔ many
    V(523369-525759)
    IV(637139-639823)


    ENSEMBL Gene Tree for KDM4D (if available)
    TreeFam Gene Tree for KDM4D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KDM4D gene
    KDM4A2  KDM4C2  KDM4E2  KDM4B2  
    5 SIMAP similar genes for KDM4D using alignment to 1 protein entry:     KDM4D_HUMAN:
    KDM4A    KDM4E    KDM4C    KDM4B    JMJD2B

    KDM4D for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for KDM4D
    PGOHUM00000242864 PGOHUM00000242865 PGOHUM00000242869


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/513 SNPs in KDM4D are shown (see all 513)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1871523841,2
    --94705065(+) TAAAAC/TCACAG 1 -- us2k10--------
    rs1915842881,2
    --94705118(+) GAAAAC/TAGATA 1 -- us2k10--------
    rs729777271,2
    C,F--94705163(+) CCATGC/TCATTT 1 -- us2k12Minor allele frequency- T:0.08WA NA 238
    rs771747271,2
    C,F--94705436(+) ATACTG/AGTAAA 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs789467511,2
    C,F--94705472(+) AACCTG/ACTTAA 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1160992171,2
    F--94705492(+) ACAAAA/TGTTTT 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs110209901,2
    C,F,H--94705612(+) TTCTGA/TCTATA 1 -- us2k112Minor allele frequency- T:0.35NA NS EA WA 918
    rs714606211,2
    C,F--94705677(+) CCTCAT/CAGATT 1 -- us2k14Minor allele frequency- C:0.15NA CSA 126
    rs1454722981,2
    --94705779(+) TACCAA/GACTCT 1 -- us2k10--------
    rs1156520871,2
    C,F--94705863(+) AAAAAT/CATCAC 1 -- us2k11Minor allele frequency- C:0.02WA 118

    HapMap Linkage Disequilibrium report for KDM4D (94706845 - 94732682 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KDM4D:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv446CNV Loss18451855
    nsv518887CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing KDM4D
    DNA2.0 Custom Variant and Variant Library Synthesis for KDM4D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609766    OMIM disorders: --

    2 diseases for KDM4D:    About MalaCards
    retinoblastoma    


    KDM4D for disorders           About GeneDecksing

    Genetic Association Database (GAD): KDM4D
    Human Genome Epidemiology (HuGE) Navigator: KDM4D (1 document)

    Export disorders for KDM4D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KDM4D gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with KDM4D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of JMJD2 family genes in silico. (PubMed id 15138608)1, 2, 3, 9 Katoh M. and Katoh M. (2004)
    2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)1, 2 Taylor T.D....Sakaki Y. (2006)
    3. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. (PubMed id 16603238)1, 2 Whetstine J.R.... Shi Y. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Structural and functional analysis of JMJD2D reveals m olecular basis for site-specific demethylation among JMJD2 demethylases. (PubMed id 23219879)1 Krishnan S. and Trievel R.C. (2013)
    7. Poly (ADP-ribose) glycohydrolase regulates retinoic acid receptor- mediated gene expression. (PubMed id 23102699)2 Le May N.... Coin F. (2012)
    8. Regulation of tumor suppressor p53 and HCT116 cell phy siology by histone demethylase JMJD2D/KDM4D. (PubMed id 22514644)1 Kim T.D....Janknecht R. (2012)
    9. Identification of the human testis protein phosphatase 1 interactome. (PubMed id 21382349)1 Fardilha M....Silva E.F. (2011)
    10. Genetic associations of variants in genes encoding HI V-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55693 HGNC: 25498 AceView: JMJD2D Ensembl:ENSG00000186280 euGenes: HUgn55693
    ECgene: KDM4D H-InvDB: KDM4D

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KDM4D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KDM4D gene:
    Search GeneIP for patents involving KDM4D

    GeneCards and IP:
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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