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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

KDELR3 Gene

protein-coding GIFtS: 56
GCID: GC22P038864

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention...

Explore 2 diseases affiliated with
KDELR3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3¹ ²
KDEL Endoplasmic Reticulum Protein Retention Receptor 3² ³
KDEL Receptor 3² ³
ERD2L3²
ER Lumen Protein Retaining Receptor 3²

External Ids:	HGNC: 6306¹	Entrez Gene: 11015²	Ensembl: ENSG00000100196⁷	UniProtKB: O43731³

Export aliases for KDELR3 gene to outside databases

Previous GC identifers: GC22P035478 GC22P037107 GC22P037189 GC22P021830

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KDELR3:

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and

animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is

dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu

(HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing

protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a

seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor

gene family, have been described. KDELR3 was the third member of the family to be identified, and it encodes a protein

highly homologous to KDELR1 and KDELR2 proteins. Two transcript variants of KDELR3 that arise by alternative splicing,

and encode different isoforms of KDELR3 receptor, have been described. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ERD23_HUMAN, O43731

Function: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the

luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor

recognizes K-D-E-L (By similarity)

Gene Wiki entry for KDELR3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000022.10 NC_018933.1 NT_011520.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the KDELR3 gene promoter:
Max1 AP-1 ATF-2 Tal-1beta POU2F1a c-Jun ITF-2 c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KDELR3 promoter sequence

Search SABiosciences Chromatin IP Primers for KDELR3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDELR3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q13.1 HGNC cytogenetic band: 22q13

KDELR3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KDELR3 gene location

GeneLoc information about chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P038864: view genomic region (about GC identifiers)

Start:	38,864,067 bp from pter	End:	38,879,452 bp from pter
Size:	15,386 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ERD23_HUMAN, O43731 (See protein sequence)

Recommended Name: ER lumen protein retaining receptor 3

Size: 214 amino acids; 25027 Da

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

Secondary accessions: A8K7T7 B8ZZ26 O95557 Q4V750 Q4V767 Q53FP4 Q53GK1

Alternative splicing: 2 isoforms: O43731-1 O43731-2

Explore the universe of human proteins at neXtProt for KDELR3: NX_O43731

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O43731

KDELR3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_006846.1 NP_057839.1

ENSEMBL proteins:

ENSP00000216014 ENSP00000386918

Reactome Protein details: O43731
Human Recombinant Protein Products:

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	Uscn Proteins for KDELR3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005789	endoplasmic reticulum membrane	TAS	--
GO:0016021	integral to membrane	IEA	--

KDELR3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for KDELR3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

KDELR3 for domains About GeneDecksing

1 InterPro domain/family:

IPR000133 ER_ret_rcpt

Graphical View of Domain Structure for InterPro Entry O43731

ProtoNet protein and cluster: O43731

1 Blocks protein family: IPB000133 ER lumen protein retaining receptor

UniProtKB/Swiss-Prot: ERD23_HUMAN, O43731

Similarity: Belongs to the ERD2 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ERD23_HUMAN, O43731

Function: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the

luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor

recognizes K-D-E-L (By similarity)

Genatlas biochemistry entry for KDELR3:

endoplasmic reticulum protein retention receptor 3 (Lys-Asp-Glu-Leu),S cerevisiae ERD2 ortholog,allowing the retrieval

of proteins from Golgi complex to ER,mimicking the brefeldin A (BFA)-like phenotype,when overexpressed

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KDELR3
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate KDELR3:
		hsa-miR-548a-3p hsa-miR-875-3p hsa-miR-137 hsa-miR-924 hsa-miR-548e hsa-miR-488 hsa-miR-619
		SwitchGear 3'UTR luciferase reporter plasmid: KDELR3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KDELR3 (see all 7) OriGene shRNA RFP: KDELR3 OriGene siRNA: KDELR3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KDELR3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for KDELR3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for KDELR3
		Search LifeMap BioReagents cell lines for KDELR3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDELR3

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	--	--
GO:0046923	ER retention sequence binding	IEA	--

KDELR3 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for KDELR3:

Decreased homologous recombina

Decreased viability

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Activation of cAMP-Dependent PKA

	Activation of cAMP-Dependent PKA	1.00			Activation of PKA through GPCR	0.71
	cAMP Pathway	0.77			PKA Signaling	0.56

G Protein Signaling Pathways

	Signal transduction cAMP signaling	0.44			Signal transduction_PKA signaling	0.23
	Signal transduction_cAMP signaling	0.44			Signal transduction PKA signaling	0.23

Activation of Chaperone Genes by XBP1(S)

	Activation of Chaperone Genes by XBP1(S)	1.00			Unfolded Protein Response	0.71
	Activation of Chaperones by IRE1alpha	0.94

Expression of KDELR3

Expression of KDELR3

1.00

Insulin receptor recycling

Vibrio cholerae infection

0.41

Pathway sources
See GeneCards unified pathways
Show all pathways

2 EMD Millipore Pathways for KDELR3

	Signal transduction cAMP signaling
	Signal transduction PKA signaling

4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KDELR3

	Activation of PKA through GPCR
	PKA Signaling
	cAMP Pathway
	Activation of cAMP-Dependent PKA

2 GeneGo (Thomson Reuters) Pathways for KDELR3

	Signal transduction cAMP signaling
	Signal transduction PKA signaling

5 Reactome Pathways for KDELR3

	Activation of Chaperone Genes by XBP1(S)
	Metabolism of proteins
	Activation of Chaperones by IRE1alpha
	Expression of KDELR3
	Unfolded Protein Response

1 Kegg Pathway (Kegg details for KDELR3):

Vibrio cholerae infection

KDELR3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for KDELR3

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5/51 Interacting proteins for KDELR3 (O43731³ ENSP00000386918⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 51)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HIST1H4A	P62805³	I2D: score=1
HIST1H4B	P62805³	I2D: score=1
HIST1H4C	P62805³	I2D: score=1
HIST1H4D	P62805³	I2D: score=1
HIST1H4E	P62805³	I2D: score=1

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006621	protein retention in ER lumen	IEA	--
GO:0006987	activation of signaling protein activity involved in unfolded protein response	TAS	--
GO:0015031	protein transport	IEA	--
GO:0016192	vesicle-mediated transport	IEA	--
GO:0030968	endoplasmic reticulum unfolded protein response	TAS	--

KDELR3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KDELR3
Search CenterWatch for drugs/clinical trials and news about KDELR3 / ERD23

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for KDELR3 gene (2 alternative transcripts):

NM_006855.2 NM_016657.1

Unigene Cluster for KDELR3:

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

Hs.528305 [show with all ESTs]

Unigene Representative Sequence: AK223238

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000216014(uc003avv.3) ENST00000409006(uc003avu.3) ENST00000471268

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KDELR3
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate KDELR3:
		hsa-miR-548a-3p hsa-miR-875-3p hsa-miR-137 hsa-miR-924 hsa-miR-548e hsa-miR-488 hsa-miR-619
		SwitchGear 3'UTR luciferase reporter plasmid: KDELR3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KDELR3 (see all 7) OriGene shRNA RFP: KDELR3 OriGene siRNA: KDELR3
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KDELR3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KDELR3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDELR3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDELR3

Additional cDNA sequence:

AK129888.1 AK222930.1 AK223238.1 AK292102.1 AL035081.1 AL035082.1 BC001277.1 BC096722.1

BC098131.1 BC098156.1 BC098336.1 CR456509.1

24/33 DOTS entries (see all 33):

DT.414432 DT.91851967 DT.75132717 DT.100677210 DT.100786370 DT.92004561 DT.100033696 DT.100642240

DT.100786367 DT.100874276 DT.92455815 DT.100663116 DT.100677201 DT.100677202 DT.100696451 DT.95300145

DT.100807909 DT.86840171 DT.120651492 DT.120651552 DT.120651555 DT.120651559 DT.120651611 DT.120651631

24/69 AceView cDNA sequences (see all 69):

AL035082 BX095409 NM_016657 CR594497 CR594712 CR590826 CR614427 BM715989

CR612711 BU634108 W21175 NM_006855 BI763227 CR456509 CR600149 AA505940

AI263473 AL035081 BF740782 BG249074 AI580151 BM803175 BX358491 AV687239

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

KDELR3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGAGCAAGT

About this image

KDELR3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Limb

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See KDELR3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KDELR3

SOURCE GeneReport for Unigene cluster: Hs.528305

SABiosciences Custom PCR Arrays for KDELR3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KDELR3 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDELR3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for KDELR3 gene from 8/28 species (see all 28) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	KDELR3¹	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein more	80.84(n) 88.79(a)		418026 NM_001012996.1 NP_001013014.1
lizard (Anolis carolinensis)	Reptilia	KDELR3⁶	--	86(a)	1 ↔ 1	GL343460.1(615957-623800)
African clawed frog (Xenopus laevis)	Amphibia	MGC64313²	hypothetical protein MGC64313	74.56(n)		AJ001533.1
zebrafish (Danio rerio)	Actinopterygii	BC057436.1²	--	77.53(n)		393613 BC057436.1
fruit fly (Drosophila melanogaster)	Insecta	KdelR³	retrograde (Golgi to ER) transport KDEL receptor	66(a)		31E1 --
worm (Caenorhabditis elegans)	Secernentea	C28H8.4³	ER lumen protein retaining receptor	61(a)		III(5978584-5980088) --
thale cress (Arabidopsis thaliana)	eudicotyledons	ERD2B⁶ ATERD2⁶ (see all 7)	ER lumen protein retaining receptor (see all 7)	45(a) 45(a) (see all 7)	many ↔ many many ↔ many (see all 7)	3(9124304-9126298) 1(10258248-10261112)
rice (Oryza sativa)	Liliopsida	-- -- (see all 5)	ER lumen protein retaining receptor, putative, exp... ER lumen protein retaining receptor, putative, exp... (see all 5)	48(a) 46(a) (see all 5)	many ↔ many many ↔ many (see all 5)	11(15840569-15844379) 4(18242359-18245654)

ENSEMBL Gene Tree for KDELR3 (if available)
TreeFam Gene Tree for KDELR3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for KDELR3 gene

KDELR1² KDELR2²

2 SIMAP similar genes for KDELR3 using alignment to 1 protein entry: ERD23_HUMAN:

KDELR1 KDELR2

KDELR3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs149952352^1,2		--	38862163(+)	`CCGGCC/TGCTCA`	2	--	us2k¹		0	--	--	--	--
rs145024554^1,2		--	38862206(+)	`CCATGA/GCAACC`	2	--	us2k¹		0	--	--	--	--
rs140525642^1,2		--	38862222(+)	`TGTAAA/GGGAAT`	2	--	us2k¹		0	--	--	--	--
rs144384036^1,2		--	38862243(+)	`TAGACC/TGTGTG`	2	--	us2k¹		0	--	--	--	--
rs147694548^1,2		--	38862319(+)	`GCCTCG/TCTTTC`	2	--	us2k¹		0	--	--	--	--
rs186736902^1,2		--	38862337(+)	`GTGAAA/GTGAGA`	2	--	us2k¹		0	--	--	--	--
rs78991353^1,2	F,	--	38862381(+)	`ATGAGT/AGCCTT`	2	--	us2k¹		1		WA	118
rs142390566^1,2		--	38862429(+)	`GTGTGC/TACATC`	2	--	us2k¹		0	--	--	--	--
rs191878696^1,2		--	38862517(+)	`TCTTTA/GGACTG`	2	--	us2k¹		0	--	--	--	--
rs138418^1,2	C,F,A,	--	38862628(+)	`GAGTTC/TGAGAC`	2	--	us2k¹		5		NA CSA	8

HapMap Linkage Disequilibrium report for KDELR3 (38864067 - 38879452 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KDELR3
1 CNV: 9847

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KDELR3

DNA2.0 Custom Variant and Variant Library Synthesis for KDELR3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KDELR3 for disorders About GeneDecksing

2 diseases for KDELR3: About MalaCards

cholera malaria

Export disorders for KDELR3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for KDELR3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KDELR3)

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{1, 2} Collins J.E.... Dunham I. (2004)
Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)^{1, 2} Collins J.E.... Dunham I. (2003)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{1, 2} Dunham I....O'Brien K.P. (1999)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
The dynamic organisation of the secretory pathway. (PubMed id 9118249)¹ Pelham H.R. (1996)
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)¹ Maruyama K. and Sugano S. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11015	HGNC: 6306	AceView: KDELR3	Ensembl:ENSG00000100196	euGenes: HUgn11015
ECgene: KDELR3	Kegg: 11015	H-InvDB: KDELR3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for KDELR3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for KDELR3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for KDELR3 gene:
Search GeneIP for patents involving KDELR3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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