KDELR1 Gene
protein-coding GIFtS: 59
GCID: GC19M048885
|
|
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention...
| |
Aliases
for KDELR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor11 2 | | KDEL Endoplasmic Reticulum Protein Retention Receptor 12 3 | | ERD2.11 2 3 | | KDEL Receptor 12 3 | | ERD21 2 | | PM232 | | HDEL1 2 | | ER Lumen Protein Retaining Receptor 12 | | Putative MAPK-Activating Protein PM232 3 | | |
Export aliases for KDELR1 gene to outside databasesPrevious GC identifers: GC19M049530 GC19M049253 GC19M053561 GC19M053577 GC19M045266 |
Summaries
for KDELR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KDELR1:
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast andanimal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins isdependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu(HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containingprotein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is aseven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptorgene family, have been described. The protein encoded by this gene was the first member of the family to beidentified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. (providedby RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ERD21_HUMAN, P24390Function: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of theluminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptorrecognizes K-D-E-L
Gene Wiki entry for KDELR1
|
Genomic Views
for KDELR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KDELR1 gene promoter:
p53 GATA-1 C/EBPalpha PPAR-gamma1 SEF-1 (1) FOXO1a STAT3 PPAR-gamma2 NF-kappaB1 FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KDELR1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDELR1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.3KDELR1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M048885: view genomic region
(about GC identifiers)
Start:
|
48,885,827 bp from pter |
End:
|
48,894,810 bp from pter |
Size:
|
8,984 bases |
Orientation:
|
minus strand |
|
Proteins
for KDELR1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ERD21_HUMAN, P24390 (See
protein sequence)Recommended Name: ER lumen protein retaining receptor 1 Size: 212 amino acids; 24542 Da
Subunit: Interacts with ARFGAP1 (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Secondary accessions: B2R6N4 Q54A39Explore the universe of human proteins at neXtProt for KDELR1: NX_P24390
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P24390
KDELR1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006792.1
ENSEMBL proteins: ENSP00000329471
Human Recombinant Protein Products for KDELR1:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
KDELR1 for ontologies About GeneDecksing
KDELR1 Antibody Products:
Assay Products for KDELR1: |
Protein
Domains /
Families
for KDELR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KDELR1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P24390ProtoNet protein and cluster: P24390 1 Blocks protein family: IPB000133 ER lumen protein retaining receptor
UniProtKB/Swiss-Prot: ERD21_HUMAN, P24390Similarity: Belongs to the ERD2 family |
Function
for KDELR1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ERD21_HUMAN, P24390Function: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of theluminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptorrecognizes K-D-E-L Genatlas biochemistry entry for KDELR1:endoplasmic reticulum protein retention receptor 1 (Lys-Asp-Glu-Leu),S cerevisiae ERD2 ortholog,allowing the retrievalof proteins from Golgi complex to ER,mimicking the brefeldin A (BFA)-like phenotype,when overexpressed
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
KDELR1 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KDELR1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KDELR1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KDELR1 (NM_006801) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KDELR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KDELR1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDELR1 |
|
Pathways & Interactions
for KDELR1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Activation of cAMP-Dependent PKA | | | 2 | G Protein Signaling Pathways | | | 3 | Insulin receptor recycling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for KDELR1
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KDELR1
2  GeneGo (Thomson Reuters) Pathways for KDELR1
1 
Kegg Pathway (Kegg details for KDELR1):
KDELR1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KDELR1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/22 Interacting proteins for KDELR1 (P243901, 3 ENSP000003294714) via UniProtKB, MINT, STRING, and/or I2D (see all 22)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| NEK6 | Q9HC981, 3, ENSP000003627024 | EBI-1043076,EBI-740364 I2D:
score=2 STRING: ENSP00000362702 | | SERINC3 | Q135301, 3, ENSP000002551754 | EBI-1043076,EBI-1045571 I2D:
score=2 STRING: ENSP00000255175 | | WBP5 | Q9UHQ71, 3, ENSP000003617404 | EBI-1043076,EBI-1051372 I2D:
score=2 STRING: ENSP00000361740 | | BZW1 | Q7L1Q61, 3, ENSP000003943164 | EBI-1043076,EBI-1046727 I2D:
score=2 STRING: ENSP00000394316 | | ARF1 | P840773, ENSP000002721024 | I2D:
score=2 STRING: ENSP00000272102 |
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
KDELR1 for ontologies About GeneDecksing
|
Drugs & Compounds
for KDELR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KDELR1 for compounds About GeneDecksing
 Browse Tocris compounds for KDELR1
1 Novoseek chemical compound relationship for KDELR1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tetrapeptide |
82.3 |
1 |
1483466 (1) |
Search CenterWatch for drugs/clinical trials and news about KDELR1 / ERD21
|
Transcripts
for KDELR1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KDELR1 gene: NM_006801.2 Unigene Cluster for KDELR1: KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 Hs.515515 [show with all ESTs]Unigene Representative Sequence: BG1160851 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000330720(uc002pja.1 uc002pjb.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KDELR1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KDELR1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KDELR1 (NM_006801) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KDELR1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KDELR1 |
Additional cDNA sequence: AB097047.1 AK075185.1 AK312647.1 BC008958.2 BC018778.1 X55885.1 23 DOTS entries: DT.95190939 DT.120020 DT.91876640 DT.95097063 DT.100031182 DT.121444837 DT.100881478 DT.95190931 DT.100881472 DT.91831933 DT.40116587 DT.91777917 DT.91777914 DT.100669532 DT.100682793 DT.100696680 DT.100881494 DT.121444798 DT.121444819 DT.121444830 DT.95190862 DT.95190932 DT.121444797 24/819 AceView cDNA sequences (see all 819): CD722990 AA513410 CR614727 AA148681 BF057520 BM668134 BU151203 BU731712 AI934045 BM969595 BQ217865 AA846736 AI925041 BM796348 BE858300 BP353262 H49773 R81004 CR600499 BX355657 CR606699 CR623592 CR598646 CB141343
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for KDELR1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KDELR1
|
Expression
for KDELR1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KDELR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTTGTACA
About this image
See KDELR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KDELR1
SOURCE GeneReport for Unigene cluster: Hs.515515
SABiosciences Custom PCR Arrays for KDELR1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KDELR1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KDELR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDELR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDELR1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDELR1 |
Orthologs
for KDELR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for KDELR1 gene from 8/36 species (see all 36) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Kdelr11 , 5 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein more1, 5 |
91.19(n)1
99.53(a)1 |
|
7 (29.57 cM)5
681371 NM_133950.21 NP_598711.11
458727725 |
lizard
(Anolis carolinensis) |
Reptilia |
KDELR16 |
-- |
83(a) |
1 ↔ 1 |
GL343329.1(130748-139013) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC060380.12 |
-- |
77.86(n) |
|
BC060380.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
KdelR1 , 3 |
retrograde (Golgi to ER) transport KDEL
receptor3
KDEL receptor1 |
75(a)3
70.13(n)1
75(a)1 |
|
31E13
344271 NM_164928.21 NP_723587.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C28H8.41 , 3 |
ER lumen protein retaining receptor3
Protein C28H8.41 |
66(a)3
65.09(n)1
67.3(a)1 |
|
III(5978584-5980088)3
1758331 NM_065881.21 NP_498282.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
ERD2(YBL040C)4
ERD21 |
HDEL receptor, an integral membrane protein that binds more4
Erd2p1 |
52.29(n)1
52.13(a)1 |
|
2(142868-142112)4
8522401, 4 NP_009513.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ERD21 |
ER lumen protein retaining receptor |
55.66(n)
51.42(a) |
|
839807 NM_102673.5 NP_564326.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.183262 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
73.35(n) |
|
AK102648.1 |
ENSEMBL Gene Tree for KDELR1 (if available)
TreeFam Gene Tree for KDELR1 (if available) |
Paralogs
for KDELR1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KDELR1 gene
- KDELR32 KDELR22
2 SIMAP similar genes for KDELR1 using alignment to 3 protein entries: ERD21_HUMAN (see all proteins):KDELR2 KDELR3
KDELR1 for paralogs About GeneDecksing
|
Genomic Variants
for KDELR1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KDELR1 (48885827 - 48894810 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for KDELR1
3 CNVs: 47965 5106 32261 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KDELR1 |
|
Disorders
/ Diseases
for KDELR1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KDELR1 for disorders About GeneDecksing
OMIM gene information: 131235
OMIM disorders: --
6  diseases for KDELR1: About MalaCardsactinobacillosis hydranencephaly erysipelas mastitis
cholera malaria
2 diseases from the University of Copenhagen DISEASES database for KDELR1:Actinobacillosis Hydranencephaly Export disorders for KDELR1 gene to outside databases
|
Publications
for KDELR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KDELR1 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with KDELR1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A human homologue of the yeast HDEL receptor. (PubMed id 2172835)1, 2, 3, 9 Lewis M.J. and Pelham H.R.B. (1990)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)
- Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport. (PubMed id 8392934)1, 2 Townsley F.M.... Pelham H.R.B. (1993)
- The KDEL receptor, ERD2, regulates intracellular traffic by recruiting a GTPase-activating protein for ARF1. (PubMed id 9405360)1, 9 Aoe T....Hsu V.W. (1997)
- Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum. (PubMed id 1310258)1, 9 Lewis M.J. and Pelham H.R. (1992)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- The KDEL receptor couples to Gaq/11 to activate Src ki nases and regulate transport through the Golgi. (PubMed id 22580821)1 Giannotta M....Sallese M. (2012)
- Cystinosin, MPDU1, SWEETs and KDELR belong to a well-d efined protein family with putative function of cargo receptors involved in vesi cle trafficking. (PubMed id 22363504)1 Saudek V. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for KDELR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KDELR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KDELR1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KDELR1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KDELR1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KDELR1 gene:
Search GeneIP for patents involving KDELR1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KDELR1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KDELR1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KDELR1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KDELR1 | | | OriGene Protein Over-expression Lysate for KDELR1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KDELR1 | | OriGene 3'-UTR Clone for KDELR1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KDELR1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KDELR1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KDELR1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KDELR1 | | OriGene Custom Protein Services for KDELR1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KDELR1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KDELR1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KDELR1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KDELR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KDELR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KDELR1 |
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| | | | Search Tocris compounds for KDELR1 |
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 | | | KDELR1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KDELR1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for KDELR1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KDELR1 |
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