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Aliases for KCTD9 Gene

Aliases for KCTD9 Gene

  • Potassium Channel Tetramerization Domain Containing 9 2 3
  • Potassium Channel Tetramerisation Domain Containing 9 2 3
  • BTB/POZ Domain-Containing Protein KCTD9 3
  • BTBD27 3

External Ids for KCTD9 Gene

Previous GeneCards Identifiers for KCTD9 Gene

  • GC08M025307
  • GC08M025341
  • GC08M023830
  • GC08M025285

Summaries for KCTD9 Gene

GeneCards Summary for KCTD9 Gene

KCTD9 (Potassium Channel Tetramerization Domain Containing 9) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and Activation of cAMP-Dependent PKA. An important paralog of this gene is KCTD17.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCTD9 Gene

Genomics for KCTD9 Gene

Regulatory Elements for KCTD9 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KCTD9 Gene

25,427,847 bp from pter
25,458,476 bp from pter
30,630 bases
Minus strand

Genomic View for KCTD9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KCTD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KCTD9 Gene

Proteins for KCTD9 Gene

  • Protein details for KCTD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BTB/POZ domain-containing protein KCTD9
    Protein Accession:
    Secondary Accessions:
    • Q6NUM8
    • Q9NXV4

    Protein attributes for KCTD9 Gene

    389 amino acids
    Molecular mass:
    42567 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA90904.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for KCTD9 Gene

Proteomics data for KCTD9 Gene at MOPED

Post-translational modifications for KCTD9 Gene

  • Ubiquitination at Lys371
  • Modification sites at PhosphoSitePlus

Other Protein References for KCTD9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KCTD9 Gene

Domains for KCTD9 Gene

Gene Families for KCTD9 Gene

Suggested Antigen Peptide Sequences for KCTD9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 BTB (POZ) domain.
  • Contains 1 BTB (POZ) domain.
  • Contains 1 KHA domain.
  • Contains 3 pentapeptide repeat domains.
genes like me logo Genes that share domains with KCTD9: view

Function for KCTD9 Gene

Gene Ontology (GO) - Molecular Function for KCTD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with KCTD9: view

Animal Model Products

miRNA for KCTD9 Gene

miRTarBase miRNAs that target KCTD9

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KCTD9

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for KCTD9 Gene

Localization for KCTD9 Gene

Subcellular locations from

Jensen Localization Image for KCTD9 Gene COMPARTMENTS Subcellular localization image for KCTD9 gene
Compartment Confidence
mitochondrion 3
cytoskeleton 1
cytosol 1
extracellular 1
lysosome 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KCTD9 Gene

Pathways for KCTD9 Gene

genes like me logo Genes that share pathways with KCTD9: view

Gene Ontology (GO) - Biological Process for KCTD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051260 protein homooligomerization IEA --
genes like me logo Genes that share ontologies with KCTD9: view

Transcripts for KCTD9 Gene

Unigene Clusters for KCTD9 Gene

Potassium channel tetramerisation domain containing 9:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KCTD9

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KCTD9 Gene

No ASD Table

Relevant External Links for KCTD9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KCTD9 Gene

mRNA expression in normal human tissues for KCTD9 Gene

Protein differential expression in normal tissues for KCTD9 Gene

This gene is overexpressed in Testis (36.4) and Seminal vesicle (31.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KCTD9 Gene

SOURCE GeneReport for Unigene cluster for KCTD9 Gene Hs.72071

genes like me logo Genes that share expressions with KCTD9: view

Expression partners for KCTD9 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KCTD9 Gene

Orthologs for KCTD9 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for KCTD9 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia KCTD9 35
  • 96.25 (n)
  • 99.2 (a)
KCTD9 36
  • 96 (a)
(Mus musculus)
Mammalia Kctd9 35
  • 91.43 (n)
  • 98.46 (a)
Kctd9 16
Kctd9 36
  • 98 (a)
(Pan troglodytes)
Mammalia KCTD9 35
  • 99.91 (n)
  • 99.74 (a)
KCTD9 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Kctd9 35
  • 91.43 (n)
  • 98.46 (a)
(Bos Taurus)
Mammalia KCTD9 36
  • 98 (a)
(Monodelphis domestica)
Mammalia KCTD9 36
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia KCTD9 36
  • 92 (a)
(Gallus gallus)
Aves KCTD9 35
  • 82.43 (n)
  • 96.14 (a)
KCTD9 36
  • 96 (a)
(Anolis carolinensis)
Reptilia KCTD9 36
  • 89 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia kctd9 35
  • 73.26 (n)
  • 85.6 (a)
Str.3830 35
(Danio rerio)
Actinopterygii zgc:113115 35
  • 74.04 (n)
  • 87.66 (a)
kctd9 36
  • 85 (a)
KCTD9 (2 of 2) 36
  • 87 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000478 35
  • 51.64 (n)
  • 50.33 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14647 35
  • 56.05 (n)
  • 57.96 (a)
CG14647 36
  • 55 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons FIP2 35
  • 47.24 (n)
  • 35.25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10153 36
  • 56 (a)
Species with no ortholog for KCTD9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KCTD9 Gene

Gene Tree for KCTD9 (if available)
Gene Tree for KCTD9 (if available)

Paralogs for KCTD9 Gene

Paralogs for KCTD9 Gene

(1) SIMAP similar genes for KCTD9 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with KCTD9: view

Variants for KCTD9 Gene

Sequence variations from dbSNP and Humsavar for KCTD9 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs958579 -- 25,441,159(-) TTTGT(C/T)GCATT intron-variant
rs965130 -- 25,430,040(-) TCATT(C/T)TGAGC intron-variant
rs1567120 -- 25,452,728(-) tttat(A/C)ttttg intron-variant
rs1567121 -- 25,450,282(-) TTGGT(C/T)ACCTC intron-variant
rs1812594 -- 25,429,881(-) CCACT(A/G)CACAT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for KCTD9 Gene

Variant ID Type Subtype PubMed ID
nsv890689 CNV Gain 21882294
nsv6125 CNV Insertion 18451855
essv1351 CNV CNV 17122850

Relevant External Links for KCTD9 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCTD9 Gene

Disorders for KCTD9 Gene

No disorders were found for KCTD9 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for KCTD9 Gene

Publications for KCTD9 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. (PMID: 11483580) Yu Y. … He F. (Genome Res. 2001) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for KCTD9 Gene

Sources for KCTD9 Gene

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