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Aliases for KCTD9 Gene

Aliases for KCTD9 Gene

  • Potassium Channel Tetramerization Domain Containing 9 2 3
  • Potassium Channel Tetramerisation Domain Containing 9 2 3
  • BTB/POZ Domain-Containing Protein KCTD9 3
  • BTBD27 3

External Ids for KCTD9 Gene

Summaries for KCTD9 Gene

GeneCards Summary for KCTD9 Gene

KCTD9 (Potassium Channel Tetramerization Domain Containing 9) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and Activation of cAMP-Dependent PKA. An important paralog of this gene is KCTD17.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCTD9 Gene

Genomics for KCTD9 Gene

Genomic Location for KCTD9 Gene

Start:
25,427,847 bp from pter
End:
25,458,476 bp from pter
Size:
30,630 bases
Orientation:
Minus strand

Genomic View for KCTD9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KCTD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KCTD9 Gene

Regulatory Elements for KCTD9 Gene

Proteins for KCTD9 Gene

  • Protein details for KCTD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L273-KCTD9_HUMAN
    Recommended name:
    BTB/POZ domain-containing protein KCTD9
    Protein Accession:
    Q7L273
    Secondary Accessions:
    • Q6NUM8
    • Q9NXV4

    Protein attributes for KCTD9 Gene

    Size:
    389 amino acids
    Molecular mass:
    42567 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA90904.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for KCTD9 Gene

Proteomics data for KCTD9 Gene at MOPED

Post-translational modifications for KCTD9 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys371

Other Protein References for KCTD9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KCTD9 Gene

Domains for KCTD9 Gene

Gene Families for KCTD9 Gene

HGNC:
  • BTBD :BTB/POZ domain containing

UniProtKB/Swiss-Prot:

KCTD9_HUMAN
Domain:
  • Contains 1 BTB (POZ) domain.:
    • Q7L273
  • Contains 1 KHA domain.:
    • Q7L273
  • Contains 3 pentapeptide repeat domains.:
    • Q7L273
genes like me logo Genes that share domains with KCTD9: view

Function for KCTD9 Gene

Gene Ontology (GO) - Molecular Function for KCTD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with KCTD9: view

miRNA for KCTD9 Gene

miRTarBase miRNAs that target KCTD9

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for KCTD9 Gene

Localization for KCTD9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KCTD9 Gene COMPARTMENTS Subcellular localization image for KCTD9 gene
Compartment Confidence
mitochondrion 3
cytoskeleton 1
cytosol 1
extracellular 1
lysosome 1
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for KCTD9 Gene

Pathways for KCTD9 Gene

genes like me logo Genes that share pathways with KCTD9: view

Gene Ontology (GO) - Biological Process for KCTD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051260 protein homooligomerization IEA --
genes like me logo Genes that share ontologies with KCTD9: view

Transcripts for KCTD9 Gene

Unigene Clusters for KCTD9 Gene

Potassium channel tetramerisation domain containing 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KCTD9 Gene

No ASD Table

Relevant External Links for KCTD9 Gene

GeneLoc Exon Structure for
KCTD9
ECgene alternative splicing isoforms for
KCTD9

Expression for KCTD9 Gene

mRNA expression in normal human tissues for KCTD9 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KCTD9 Gene

SOURCE GeneReport for Unigene cluster for KCTD9 Gene Hs.72071

genes like me logo Genes that share expressions with KCTD9: view

Orthologs for KCTD9 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for KCTD9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KCTD9 36
  • 99.91 (n)
  • 99.74 (a)
KCTD9 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KCTD9 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KCTD9 36
  • 96.25 (n)
  • 99.2 (a)
KCTD9 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Kctd9 36
  • 91.43 (n)
  • 98.46 (a)
Kctd9 16
Kctd9 37
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KCTD9 37
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KCTD9 37
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Kctd9 36
  • 91.43 (n)
  • 98.46 (a)
chicken
(Gallus gallus)
Aves KCTD9 36
  • 82.43 (n)
  • 96.14 (a)
KCTD9 37
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KCTD9 37
  • 89 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kctd9 36
  • 73.26 (n)
  • 85.6 (a)
Str.3830 36
zebrafish
(Danio rerio)
Actinopterygii kctd9 37
  • 85 (a)
OneToMany
KCTD9 (2 of 2) 37
  • 87 (a)
OneToMany
zgc:113115 36
  • 74.04 (n)
  • 87.66 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000478 36
  • 51.64 (n)
  • 50.33 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14647 36
  • 56.05 (n)
  • 57.96 (a)
CG14647 37
  • 55 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons FIP2 36
  • 47.24 (n)
  • 35.25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10153 37
  • 56 (a)
OneToOne
Species with no ortholog for KCTD9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KCTD9 Gene

ENSEMBL:
Gene Tree for KCTD9 (if available)
TreeFam:
Gene Tree for KCTD9 (if available)

Paralogs for KCTD9 Gene

Paralogs for KCTD9 Gene

Selected SIMAP similar genes for KCTD9 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with KCTD9: view

Variants for KCTD9 Gene

Sequence variations from dbSNP and Humsavar for KCTD9 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs958579 -- 25,441,159(-) TTTGT(C/T)GCATT intron-variant
rs965130 -- 25,430,040(-) TCATT(C/T)TGAGC intron-variant
rs1567120 -- 25,452,728(-) tttat(A/C)ttttg intron-variant
rs1567121 -- 25,450,282(-) TTGGT(C/T)ACCTC intron-variant
rs1812594 -- 25,429,881(-) CCACT(A/G)CACAT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for KCTD9 Gene

Variant ID Type Subtype PubMed ID
nsv890689 CNV Gain 21882294
nsv6125 CNV Insertion 18451855
essv1351 CNV CNV 17122850

Relevant External Links for KCTD9 Gene

HapMap Linkage Disequilibrium report
KCTD9

Disorders for KCTD9 Gene

No disorders were found for KCTD9 Gene.

No data available for UniProtKB/Swiss-Prot for KCTD9 Gene

Publications for KCTD9 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. (PMID: 11483580) Yu Y. … He F. (Genome Res. 2001) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for KCTD9 Gene

Sources for KCTD9 Gene

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