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KCTD9 Gene

protein-coding   GIFtS: 48
GCID: GC08M025285

Potassium Channel Tetramerization Domain Containing 9

(Previous name: potassium channel tetramerisation domain containing 9)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Potassium Channel Tetramerization Domain Containing 91 2
Potassium Channel Tetramerisation Domain Containing 91 2
BTBD272
BTB/POZ Domain-Containing Protein KCTD92

External Ids:    HGNC: 224011   Entrez Gene: 547932   Ensembl: ENSG000001047567   UniProtKB: Q7L2733   

Export aliases for KCTD9 gene to outside databases

Previous GC identifers: GC08M025307 GC08M025341 GC08M023830


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KCTD9 Gene:
KCTD9 (potassium channel tetramerization domain containing 9) is a protein-coding gene. An important paralog of this gene is KCTD17.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_167187.2  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCTD9 gene promoter:
         TBP   Sp1   FOXO3   NF-kappaB   FOXO3b   C/EBPalpha   FOXO3a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCTD9 promoter sequence
   Search Chromatin IP Primers for KCTD9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCTD9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.1   Ensembl cytogenetic band:  8p21.2   HGNC cytogenetic band: 8p21.1

KCTD9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD9 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M025285:  view genomic region     (about GC identifiers)

Start:
25,285,363 bp from pter      End:
25,315,992 bp from pter
Size:
30,630 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KCTD9_HUMAN, Q7L273 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein KCTD9  
Size: 389 amino acids; 42567 Da
Sequence caution: Sequence=BAA90904.1; Type=Erroneous initiation;
Secondary accessions: Q6NUM8 Q9NXV4

Explore the universe of human proteins at neXtProt for KCTD9: NX_Q7L273

Explore proteomics data for KCTD9 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys371
  • Modification sites at PhosphoSitePlus

  • See KCTD9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060104.2  
    ENSEMBL proteins: 
     ENSP00000221200   ENSP00000466874   ENSP00000467904  

    KCTD9 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Novus Biologicals KCTD9 Protein
    Novus Biologicals KCTD9 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KCTD9

     
    Search eBioscience for Proteins for KCTD9 

    KCTD9 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals KCTD9 Antibodies
    Abcam antibodies for KCTD9
    Cloud-Clone Corp. Antibodies for KCTD9
    Search ThermoFisher Antibodies for KCTD9
    LSBio Antibodies in human, mouse, rat for KCTD9

    KCTD9 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for KCTD9
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KCTD9
    Cloud-Clone Corp. CLIAs for KCTD9
    Search eBioscience for ELISAs for KCTD9 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing

    5 InterPro protein domains:
     IPR000210 BTB/POZ-like
     IPR001646 5peptide_repeat
     IPR011333 BTB/POZ_fold
     IPR021789 K_channel_plant
     IPR003131 T1-type_BTB

    Graphical View of Domain Structure for InterPro Entry Q7L273

    ProtoNet protein and cluster: Q7L273

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB001646 Pentapeptide repeat


    UniProtKB/Swiss-Prot: KCTD9_HUMAN, Q7L273
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 1 KHA domain
    Similarity: Contains 3 pentapeptide repeat domains


    Find genes that share domains with KCTD9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KCTD9           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCTD9
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KCTD9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KCTD9
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KCTD9

    miRNA
    Products:
        
    miRTarBase miRNAs that target KCTD9:
    hsa-mir-26b-5p (MIRT029678)

    Block miRNA regulation of human, mouse, rat KCTD9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD9 (see all 37):
    hsa-miR-218 hsa-miR-105 hsa-miR-502-3p hsa-miR-183* hsa-miR-4257 hsa-miR-3622a-5p hsa-miR-203 hsa-miR-186*
    SwitchGear 3'UTR luciferase reporter plasmidKCTD9 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KCTD9
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD9

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KCTD9

    Clone
    Products:
         
    OriGene clones in human, mouse for KCTD9 (see all 7)
    OriGene ORF clones in mouse, rat for KCTD9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KCTD9 (NM_017634)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD9

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KCTD9
    Browse ESI BIO Cell Lines and PureStem Progenitors for KCTD9 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytoskeleton1
    cytosol1
    extracellular1
    lysosome1
    nucleus1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KCTD9 About    
    See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Bitter Taste Signaling0.44
    Melatonin Signaling0.72
    Sperm Motility0.37
    Cellular Effects of Sildenafil0.46
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47
    Cholera Infection0.40
    Aldosterone Signaling in Epithelial Cells0.47
    4Hepatic ABC Transporters
    Hepatic ABC Transporters0.41
    MODY (Maturity-Onset Diabetes of Young)0.41

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for KCTD9 (see all 13)
        Cholera Infection
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Hepatic ABC Transporters
    PKA Signaling
    Sweet Taste Signaling


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KCTD9
    Interactions:

        Search GeneGlobe Interaction Network for KCTD9

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for KCTD9 (Q7L2733 ENSP000002212004) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MED20Q9H9443I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    EGFRENSP000002754934STRING: ENSP00000275493
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051260protein homooligomerization IEA--

    Find genes that share ontologies with KCTD9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KCTD9



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KCTD9 gene: 
    NM_017634.3  

    Unigene Clusters for KCTD9:

    Potassium channel tetramerisation domain containing 9
    Hs.72071  [show with all ESTs], Hs.188763  [show with all ESTs]
    Unigene Representative Sequences: NM_017634, BQ219633
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221200(uc011lad.2 uc003xeo.3) ENST00000519665 ENST00000523140
    ENST00000522493 ENST00000518067 ENST00000518997 ENST00000523294 ENST00000521458
    ENST00000524217 ENST00000520405 ENST00000517914
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KCTD9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD9 (see all 37):
    hsa-miR-218 hsa-miR-105 hsa-miR-502-3p hsa-miR-183* hsa-miR-4257 hsa-miR-3622a-5p hsa-miR-203 hsa-miR-186*
    SwitchGear 3'UTR luciferase reporter plasmidKCTD9 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KCTD9
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD9
    Clone
    Products:
         
    OriGene clones in human, mouse for KCTD9 (see all 7)
    OriGene ORF clones in mouse, rat for KCTD9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KCTD9 (NM_017634)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD9
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for KCTD9
    OriGene qSTAR qPCR primer pairs in human, mouse for KCTD9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD9
      QuantiTect SYBR Green Assays in human, mouse, rat KCTD9
      QuantiFast Probe-based Assays in human, mouse, rat KCTD9

    Additional mRNA sequence: 

    AK298518.1 BC021216.2 

    12 DOTS entries:

    DT.311533  DT.91924119  DT.99927591  DT.100770239  DT.121469138  DT.121469151  DT.100700232  DT.40286472 
    DT.86841883  DT.97843817  DT.97843819  DT.121294997 

    Selected AceView cDNA sequences (see all 135):

    AI374591 AI278056 CR621533 BM995083 AI125289 BU178348 BM980234 BU149129 
    BM995898 BM991759 CB124518 BM669215 BQ214416 AI125769 CA445587 BX282153 
    AF075015 BC021216 NM_017634 BE222126 AW292224 AI696400 AA366987 CA450242 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KCTD9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTGCTTAG
    KCTD9 Expression
    About this image

    KCTD9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KCTD9 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.72071 Hs.188763
        Custom PCR Arrays for KCTD9
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for KCTD9
    OriGene qSTAR qPCR primer pairs in human, mouse for KCTD9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD9
    QuantiTect SYBR Green Assays in human, mouse, rat KCTD9
    QuantiFast Probe-based Assays in human, mouse, rat KCTD9
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KCTD9 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kctd91 , 5 potassium channel tetramerisation domain containing more1, 5 91.43(n)1
    98.46(a)1
      14 (34.66 cM)5
    1054401  NM_001111028.11  NP_001104498.11 
     677159375 
    chicken
    (Gallus gallus)
    Aves KCTD91 potassium channel tetramerisation domain containing more 82.43(n)
    96.14(a)
      419526  NM_001012839.1  NP_001012857.1 
    lizard
    (Anolis carolinensis)
    Reptilia KCTD96
    potassium channel tetramerization domain containin...
    89(a)
    1 ↔ 1
    GL343422.1(524445-536839)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.38302 Transcribed sequence with strong similarity to protein more 78.39(n)    AL872185.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1131151 zgc:113115 74.04(n)
    87.66(a)
      541442  NM_001013567.2  NP_001013585.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG146471 CG14647 56.05(n)
    57.96(a)
      40558  NM_141208.5  NP_649465.6 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons FIP21 FIP2 47.24(n)
    35.25(a)
      835591  NM_124882.3  NP_200311.1 


    ENSEMBL Gene Tree for KCTD9 (if available)
    TreeFam Gene Tree for KCTD9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KCTD9 gene
    KCTD172  KCTD52  KCTD22  
    1 SIMAP similar gene for KCTD9 using alignment to 3 protein entries:     KCTD9_HUMAN (see all proteins):
    KCTD5

    Find genes that share paralogs with KCTD9           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for KCTD9 (see all 7)
    PGOHUM00000238729 PGOHUM00000257923 PGOHUM00000237281 PGOHUM00000235191 PGOHUM00000257186


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KCTD9 (see all 594)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1424961211,2
    --25285055(+) CCAACA/CGCTGT 1 -- int10--------
    rs1399351971,2
    --25285266(+) TAAACA/GAATTA 1 -- int10--------
    rs1871828051,2
    --25285280(+) GGGAGA/GCAGTC 1 -- int10--------
    rs1434682251,2
    --25285330(+) CATGGG/TGTATT 1 -- int10--------
    rs2004762711,2
    C--25285381(-) TTAAAG/TTAAAT 1 -- ut310--------
    rs1913107651,2
    --25285412(+) ATCCAC/TAACAA 1 -- ut310--------
    rs1996371421,2
    --25285425(+) TAAGT-/TA    
       TACTG
    TATTT
    1 -- ut310--------
    rs1844100371,2
    --25285498(+) CAAAAG/TACAGA 1 -- ut310--------
    rs28744261,2
    --25285580(+) TATACA/GTTAGA 1 -- ut31 ese30--------
    rs23210521,2
    C--25285680(+) TGAATG/AAATAC 1 -- ut312Minor allele frequency- A:0.00NA 4

    HapMap Linkage Disequilibrium report for KCTD9 (25285363 - 25315992 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for KCTD9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6125CNV Insertion18451855
    nsv890689CNV Gain21882294
    essv1351CNV CNV17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KCTD9
    DNA2.0 Custom Variant and Variant Library Synthesis for KCTD9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KCTD9 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with KCTD9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. (PubMed id 11483580)1, 3 Yu Y....He F. (Genome Res. 2001)
    4. KCTD9 contributes to liver injury through NK cell activation during hepatitis B virus-induced acute-on-chronic liver failure. (PubMed id 23376586)1 Chen T....Ning Q. (Clin. Immunol. 2013)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54793 HGNC: 22401 AceView: KCTD9 Ensembl:ENSG00000104756 euGenes: HUgn54793
    ECgene: KCTD9 H-InvDB: KCTD9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KCTD9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KCTD9 gene:
    Search GeneIP for patents involving KCTD9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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