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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KCTD5 Gene

protein-coding   GIFtS: 49
GCID: GC16P002732

Potassium Channel Tetramerization Domain Containing 5

(Previous name: potassium channel tetramerisation domain containing 5)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Potassium Channel Tetramerization Domain Containing 51 2
Potassium Channel Tetramerisation Domain Containing 51 2
BTB/POZ Domain-Containing Protein KCTD52

External Ids:    HGNC: 214231   Entrez Gene: 544422   Ensembl: ENSG000001679777   OMIM: 6112855   UniProtKB: Q9NXV23   

Export aliases for KCTD5 gene to outside databases

Previous GC identifer: GC16P002672


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KCTD5 Gene: 
KCTD5 (potassium channel tetramerization domain containing 5) is a protein-coding gene. Diseases associated with KCTD5 include rectal neoplasm, and agoraphobia, and among its related super-pathways are Melatonin Signaling and Activation of cAMP-Dependent PKA. GO annotations related to this gene include protein binding. An important paralog of this gene is KCTD17.

UniProtKB/Swiss-Prot: KCTD5_HUMAN, Q9NXV2
Function: Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex.
Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KCTD5 gene promoter:
         MEF-2   HSF1 (long)   RelA   E47   C/EBPalpha   MEF-2A   CHOP-10   ARP-1   HSF1short   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCTD5 promoter sequence
   Search SABiosciences Chromatin IP Primers for KCTD5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCTD5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

KCTD5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD5 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P002732:  view genomic region     (about GC identifiers)

Start:
2,732,476 bp from pter      End:
2,759,031 bp from pter
Size:
26,556 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KCTD5_HUMAN, Q9NXV2 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein KCTD5  
Size: 234 amino acids; 26093 Da
Subunit: Homopentamer. Interacts (via C-terminus) with GRASP55/GORASP2. Interacts with CUL3 and with ubiquitinated
proteins. Interacts with adeno-associated virus 2 (AAV-2) REP proteins
Subcellular location: Cytoplasm, cytosol. Nucleus. Note=Predominantly cytoplasmic, translocated to the nucleus
upon interaction with Rep proteins
3 PDB 3D structures from and Proteopedia for KCTD5:
3DRX (3D)        3DRY (3D)        3DRZ (3D)    
Secondary accessions: D3DU96

Explore the universe of human proteins at neXtProt for KCTD5: NX_Q9NXV2

Explore proteomics data for KCTD5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NXV2

  • KCTD5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KCTD5 Protein Expression
    REFSEQ proteins: NP_061865.1  
    ENSEMBL proteins: 
     ENSP00000301738   ENSP00000456844  

    Human Recombinant Protein Products for KCTD5: 
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    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for KCTD5
    Cloud-Clone Corp. Proteins for KCTD5 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005829cytosol IDA18573101

    KCTD5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR003131 T1-type_BTB

    Graphical View of Domain Structure for InterPro Entry Q9NXV2

    ProtoNet protein and cluster: Q9NXV2

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: KCTD5_HUMAN, Q9NXV2
    Domain: The BTB (POZ) domain is atypical and mediates the formation of a homopentamer instead of a homotetramer.
    Homopentamerization is due to the presence of 4 residues in the BTB (POZ) domain: Leu-56, Gly-100, Val-112 and
    Ala-118
    Similarity: Contains 1 BTB (POZ) domain


    KCTD5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCTD5_HUMAN, Q9NXV2
    Function: Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex.
    Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4
    Induction: Up-regulated in peripheral blood lymphocytes stimulated through the T-cell receptor

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18573101
         
    KCTD5 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for KCTD5:
     Increased S DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KCTD5 
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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate KCTD5 (see all 40):
    hsa-miR-1224-3p hsa-miR-29a hsa-miR-30d hsa-miR-548l hsa-miR-183* hsa-miR-30a hsa-miR-124 hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidKCTD5 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KCTD5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Bitter Taste Signaling0.44
    Melatonin Signaling0.72
    Sperm Motility0.37
    Cellular Effects of Sildenafil0.46
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47
    Cholera Infection0.40
    Aldosterone Signaling in Epithelial Cells0.47
    4Hepatic ABC Transporters
    Hepatic ABC Transporters0.41
    MODY (Maturity-Onset Diabetes of Young)0.41

    5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KCTD5 (see all 13)
        Cholera Infection
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Hepatic ABC Transporters
    PKA Signaling
    Sweet Taste Signaling


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCTD5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/32 Interacting proteins for KCTD5 (Q9NXV23 ENSP000003017384) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CUL3Q136183, ENSP000002644144I2D: score=4 STRING: ENSP00000264414
    CUL2Q136173, ENSP000003638804I2D: score=2 STRING: ENSP00000363880
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    GORASP2Q9H8Y83, ENSP000002341604I2D: score=1 STRING: ENSP00000234160
    ELF3P785453, ENSP000003526734I2D: score=1 STRING: ENSP00000352673
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019048modulation by virus of host morphology or physiology IEA--
    GO:0051260protein homooligomerization IEA--

    KCTD5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KCTD5

    Search CenterWatch for drugs/clinical trials and news about KCTD5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KCTD5 gene: 
    NM_018992.3  

    Unigene Cluster for KCTD5:

    Potassium channel tetramerisation domain containing 5
    Hs.61960  [show with all ESTs]
    Unigene Representative Sequence: NM_018992
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000301738(uc002crd.3) ENST00000570005 ENST00000564246 ENST00000564195
    ENST00000569689
    miRNA
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    hsa-miR-1224-3p hsa-miR-29a hsa-miR-30d hsa-miR-548l hsa-miR-183* hsa-miR-30a hsa-miR-124 hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidKCTD5 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCTD5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCTD5

    Additional mRNA sequence: 

    AK000047.1 BC007314.2 

    7 DOTS entries:

    DT.416830  DT.87015721  DT.95094660  DT.95094652  DT.120706436  DT.95094661  DT.95179670 

    24/210 AceView cDNA sequences (see all 210):

    AW663453 AA977802 BM976056 AA809650 AI040098 CA453977 BC007314 AI380288 
    AI827388 BI196930 AA429995 AI690443 BM929824 AI239460 BG177168 BQ270463 
    AI560991 AW628607 AW593875 CF141411 AW303513 BM684705 AI863698 AI269482 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for KCTD5    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                    -                     
    SP2:                                          
    SP3:              -     -                     


    ECgene alternative splicing isoforms for KCTD5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KCTD5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTGAAAAC
    KCTD5 Expression
    About this image


    See KCTD5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KCTD5

    SOURCE GeneReport for Unigene cluster: Hs.61960
        SABiosciences Custom PCR Arrays for KCTD5
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KCTD5 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kctd51 , 5 potassium channel tetramerisation domain containing more1, 5 91.45(n)1
    96.15(a)1
      17 (12.22 cM)5
    692591  NM_027008.21  NP_081284.21 
     240477345 
    chicken
    (Gallus gallus)
    Aves KCTD51 potassium channel tetramerisation domain containing more 79.53(n)
    90.79(a)
      416589  XM_414889.2  XP_414889.1 
    lizard
    (Anolis carolinensis)
    Reptilia KCTD56
    Uncharacterized protein
    71(a)
    1 ↔ 1
    GL343612.1(233374-247891)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU914277.12   -- 77.96(n)    BU914277.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kctd51 potassium channel tetramerisation domain containing more 77.83(n)
    90.91(a)
      322008  NM_207049.1  NP_996932.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG328101 CG32810 65.78(n)
    65.78(a)
      31110  NM_130570.2  NP_569926.2 
    worm
    (Caenorhabditis elegans)
    Secernentea tag-3036
    Protein TAG-303
    39(a)
    1 → many
    X(1300149-1308135)


    ENSEMBL Gene Tree for KCTD5 (if available)
    TreeFam Gene Tree for KCTD5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KCTD5 gene
    KCTD172  KCTD22  KCTD92  
    5 SIMAP similar genes for KCTD5 using alignment to 2 protein entries:     KCTD5_HUMAN (see all proteins):
    KCTD17    KCTD2    SHKBP1    KCTD9    KCTD6

    KCTD5 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for KCTD5
    PGOHUM00000248966 PGOHUM00000241158


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/620 SNPs in KCTD5 are shown (see all 620)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1907666001,2
    --2730594(+) CAAACA/TTGACA 1 -- us2k10--------
    rs1830812911,2
    --2730607(+) AGCCTA/TTGTTG 1 -- us2k10--------
    rs1490651871,2
    C--2730638(+) TCTTAC/GGCAGC 1 -- us2k10--------
    rs1177620941,2
    C,F--2730855(+) TCCCCA/GTAACT 1 -- us2k11Minor allele frequency- G:0.07NA 120
    rs1882615531,2
    --2730874(+) CCATAC/TGAAGA 1 -- us2k10--------
    rs31127101,2
    --2730956(+) TAACCA/GTCTGG 1 -- us2k10--------
    rs31127111,2
    --2730957(+) AACCGC/TCTGGC 1 -- us2k10--------
    rs1130493911,2
    C,F--2730977(+) ACGAAC/TAGGGG 1 -- us2k12Minor allele frequency- T:0.33WA CSA 3
    rs1854025691,2
    --2730987(+) GTCATC/TGTGCT 1 -- us2k10--------
    rs1483536091,2
    --2730998(+) GGTAAA/CAGCCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KCTD5 (2732476 - 2759031 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/24 variations for KCTD5 (see all 24):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2421848CNV Duplication20811451
    esv2422427CNV Duplication17116639
    dgv2545n71CNV Loss21882294
    dgv2572n71CNV Loss21882294
    nsv905165CNV Loss21882294
    nsv905152CNV Loss21882294
    nsv817714CNV Loss17921354
    nsv905139CNV Loss21882294
    nsv519596CNV Loss19592680
    nsv471073CNV Loss18288195

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611285    OMIM disorders: --

    8 diseases for KCTD5:    About MalaCards
    rectal neoplasm    agoraphobia    constipation    pterygium
    maturity-onset diabetes of the young    cholera    hepatitis    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for KCTD5:
    Agoraphobia     Rectal neoplasm

    KCTD5 for disorders           About GeneDecksing


    Export disorders for KCTD5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KCTD5 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with KCTD5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Pentameric assembly of potassium channel tetramerization domain-containing protein 5. (PubMed id 19361449)1, 2 Dementieva I.S....Goldstein S.A. (2009)
    2. KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. (PubMed id 18573101)1, 2 Bayon Y.... Alonso A. (2008)
    3. Identification of a cytoplasmic interaction partner of the large regulatory proteins Rep78/Rep68 of adeno-associated virus type 2 (AAV- 2). (PubMed id 17239418)1, 2 Weger S.... Heilbronn R. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    7. Quantitative study of the interactome of PKCz involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (2013)
    8. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    9. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)
    10. The P-body component USP52/PAN2 is a novel regulator o f HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54442 HGNC: 21423 AceView: KCTD5 Ensembl:ENSG00000167977 euGenes: HUgn54442
    ECgene: KCTD5 H-InvDB: KCTD5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KCTD5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KCTD5 gene:
    Search GeneIP for patents involving KCTD5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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