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KCTD2 Gene

protein-coding   GIFtS: 50
GCID: GC17P073051

Potassium Channel Tetramerization Domain Containing 2

(Previous name: potassium channel tetramerisation domain containing 2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Potassium Channel Tetramerization Domain Containing 21 2
Potassium Channel Tetramerisation Domain Containing 21 2
Potassium Channel Tetramerization Domain-Containing Protein 22 3
KIAA01763 5
BTB/POZ Domain-Containing Protein KCTD22

External Ids:    HGNC: 212941   Entrez Gene: 235102   Ensembl: ENSG000001809017   OMIM: 6134225   UniProtKB: Q146813   
ORGUL members:         

Export aliases for KCTD2 gene to outside databases

Previous GC identifers: GC17P073508 GC17P073640 GC17P070554 GC17P073043 GC17P068453 GC17P073029 GC17P073034


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KCTD2 Gene:
KCTD2 (potassium channel tetramerization domain containing 2) is a protein-coding gene. Diseases associated with KCTD2 include maturity-onset diabetes of the young, and cholera. An important paralog of this gene is KCTD17.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCTD2 gene promoter:
         Pbx1a   LUN-1   STAT5A   Ik-3   GATA-2   RORalpha1   AREB6   PPAR-alpha   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCTD2 promoter sequence
   Search Chromatin IP Primers for KCTD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCTD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.2

KCTD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P073051:  view genomic region     (about GC identifiers)

Start:
73,028,670 bp from pter      End:
73,061,984 bp from pter
Size:
33,315 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: KCTD2_HUMAN, Q14681 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein KCTD2  
Size: 263 amino acids; 28527 Da
Sequence caution: Sequence=BAA11493.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Explore the universe of human proteins at neXtProt for KCTD2: NX_Q14681

Explore proteomics data for KCTD2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KCTD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056168.1  
    ENSEMBL proteins: 
     ENSP00000464630   ENSP00000364435   ENSP00000312814  

    KCTD2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KCTD2

    KCTD2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for KCTD2
    Abcam antibodies for KCTD2
    Cloud-Clone Corp. Antibodies for KCTD2
    Search ThermoFisher Antibodies for KCTD2
    LSBio Antibodies in human, mouse, rat for KCTD2

    KCTD2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KCTD2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KCTD2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KCTD2
    Cloud-Clone Corp. CLIAs for KCTD2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR003131 T1-type_BTB

    Graphical View of Domain Structure for InterPro Entry Q14681

    ProtoNet protein and cluster: Q14681

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: KCTD2_HUMAN, Q14681
    Similarity: Contains 1 BTB (POZ) domain


    KCTD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0032403protein complex binding IDA--
         
    KCTD2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCTD2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KCTD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KCTD2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KCTD2

    miRNA
    Products:
        
    miRTarBase miRNAs that target KCTD2:
    hsa-mir-149-5p (MIRT045532), hsa-mir-423-5p (MIRT038107), hsa-mir-181a-5p (MIRT047312), hsa-mir-339-5p (MIRT042759)

    Block miRNA regulation of human, mouse, rat KCTD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD2 (see all 26):
    hsa-miR-3910 hsa-miR-320a hsa-miR-1197 hsa-miR-657 hsa-miR-1271 hsa-miR-766 hsa-miR-9 hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmidKCTD2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KCTD2
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KCTD2

    Clone
    Products:
         
    OriGene clones in human, mouse for KCTD2 (see all 6)
    OriGene ORF clones in mouse, rat for KCTD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KCTD2 (NM_015353)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KCTD2
    Browse ESI BIO Cell Lines and PureStem Progenitors for KCTD2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    nucleus2
    cytosol1
    golgi apparatus1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KCTD2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Bitter Taste Signaling0.44
    Melatonin Signaling0.72
    Sperm Motility0.37
    Cellular Effects of Sildenafil0.46
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47
    Cholera Infection0.40
    Aldosterone Signaling in Epithelial Cells0.47
    4Hepatic ABC Transporters
    Hepatic ABC Transporters0.41
    MODY (Maturity-Onset Diabetes of Young)0.41

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for KCTD2 (see all 13)
        Cholera Infection
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Hepatic ABC Transporters
    PKA Signaling
    Sweet Taste Signaling


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KCTD2
    Interactions:

        Search GeneGlobe Interaction Network for KCTD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for KCTD2 (Q146813 ENSP000003128144) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PSMA7O148183, ENSP000003599104I2D: score=1 STRING: ENSP00000359910
    PSMD2Q132003, ENSP000003101294I2D: score=5 STRING: ENSP00000310129
    RAPSNQ137023, ENSP000002988544I2D: score=1 STRING: ENSP00000298854
    CALRP277973I2D: score=5 
    JMJD6Q6NYC13I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051260protein homooligomerization IEA--

    KCTD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KCTD2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KCTD2 gene: 
    NM_015353.2  

    Unigene Cluster for KCTD2:

    Potassium channel tetramerisation domain containing 2
    Hs.514468  [show with all ESTs]
    Unigene Representative Sequence: NM_015353
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579242 ENST00000582840 ENST00000584767(uc010dfy.1) ENST00000584570
    ENST00000581589 ENST00000375286(uc010dfz.3 uc002jmq.3) ENST00000322444(uc002jmp.3)
    ENST00000577516 ENST00000579230
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KCTD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD2 (see all 26):
    hsa-miR-3910 hsa-miR-320a hsa-miR-1197 hsa-miR-657 hsa-miR-1271 hsa-miR-766 hsa-miR-9 hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmidKCTD2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KCTD2
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD2
    Clone
    Products:
         
    OriGene clones in human, mouse for KCTD2 (see all 6)
    OriGene ORF clones in mouse, rat for KCTD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KCTD2 (NM_015353)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KCTD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD2
      QuantiTect SYBR Green Assays in human, mouse, rat KCTD2
      QuantiFast Probe-based Assays in human, mouse, rat KCTD2

    Additional mRNA sequence: 

    AF055014.1 AK307083.1 AK310690.1 AK311278.1 BC009633.1 BC033329.1 BC047910.1 BC072404.1 
    BC080561.1 D79998.1 

    12 DOTS entries:

    DT.91945742  DT.100840834  DT.444915  DT.102838146  DT.95275790  DT.121003634  DT.121003637  DT.75103828 
    DT.95275789  DT.97824536  DT.121003642  DT.40263079 

    Selected AceView cDNA sequences (see all 191):

    AI304883 AI168196 BE887054 BM719200 AA810248 BU754022 AA348664 BX092723 
    AA349765 CA388985 AW303459 BC033329 AA429851 AW197904 BU728628 AW799250 
    CA407154 CD369080 BM669463 AA368475 BM809922 AA325348 BU731271 AI564886 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for KCTD2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                                
    SP2:                                                


    ECgene alternative splicing isoforms for KCTD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KCTD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAATGAGGT
    KCTD2 Expression
    About this image

    KCTD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KCTD2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.514468
        Custom PCR Arrays for KCTD2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for KCTD2
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    QuantiFast Probe-based Assays in human, mouse, rat KCTD2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KCTD2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kctd21 , 5 potassium channel tetramerisation domain containing more1, 5 90.11(n)1
    96.2(a)1
      11 (80.84 cM)5
    703821  NM_183285.31  NP_899108.31 
     1154201285 
    chicken
    (Gallus gallus)
    Aves KCTD21 potassium channel tetramerisation domain containing more 83.85(n)
    95.36(a)
      422116  NM_001007913.1  NP_001007914.1 
    lizard
    (Anolis carolinensis)
    Reptilia KCTD26
    potassium channel tetramerization domain containin...
    87(a)
    1 ↔ 1
    2(114874372-114896026)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia kctd21 potassium channel tetramerisation domain containing more 75.15(n)
    84.82(a)
      100485398  XM_004918472.1  XP_004918529.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kctd21 potassium channel tetramerisation domain containing more 78.07(n)
    94.82(a)
      751724  NM_001045434.1  NP_001038899.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta inc6
    insomniac
    57(a)
    1 → many
    X(1407092-1411653)
    worm
    (Caenorhabditis elegans)
    Secernentea tag-3031 tag-303 57.69(n)
    57.51(a)
      180473  NM_075838.3  NP_508239.1 


    ENSEMBL Gene Tree for KCTD2 (if available)
    TreeFam Gene Tree for KCTD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KCTD2 gene
    KCTD172  KCTD52  KCTD92  
    2 SIMAP similar genes for KCTD2 using alignment to 4 protein entries:     KCTD2_HUMAN (see all proteins):
    KCTD5    KCTD17

    KCTD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KCTD2 (see all 412)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1119388181,2
    F--73045125(+) ATACAT/AAAAGC 1 -- int13Minor allele frequency- A:0.06CSA WA 124
    rs1478599111,2
    --73045146(+) TTACCA/GATAGT 1 -- int10--------
    rs1414324171,2
    --73045235(+) TGACAA/CAGATG 1 -- int10--------
    rs1113283401,2
    C,F--73045239(+) AAAGAT/CGGTGA 1 -- int12Minor allele frequency- C:0.08CSA WA 122
    rs1432579871,2
    --73045241(+) AGATGA/GTGAAA 1 -- int10--------
    rs2018536291,2
    --73045272(+) AAATAC/TTCCTC 1 -- int10--------
    rs2013431441,2
    C--73045430(+) TAAGCA/GCACTG 1 -- int10--------
    rs1504349761,2
    C--73045476(+) TTTAAA/CGTTGT 1 -- int10--------
    rs728445331,2
    C,F--73045495(+) TTTCAA/GTTTTG 1 -- int11Minor allele frequency- G:0.02NA 120
    rs1918227441,2
    --73045608(+) CCTTAG/TGCTTT 1 -- int10--------

    HapMap Linkage Disequilibrium report for KCTD2 (73028670 - 73061984 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KCTD2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908744CNV Loss21882294
    nsv908753CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KCTD2
    DNA2.0 Custom Variant and Variant Library Synthesis for KCTD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613422    OMIM disorders: --

    4 diseases for KCTD2:    About MalaCards
    maturity-onset diabetes of the young    cholera    hepatitis    neuronitis


    KCTD2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KCTD2

    Export disorders for KCTD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KCTD2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with KCTD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Whole genome association scan for genetic polymorphisms influencing information processing speed. (PubMed id 21130836)1, 4 Luciano M....Deary I.J. (Biol Psychol 2011)
    2. Radiation hybrid map, physical map, and low-pass genomic sequence of the canine prcd region on CFA9 and comparative mapping with the syntenic region on human chromosome 17. (PubMed id 12620391)1, 3 Sidjanin D.J....Aguirre G. (Genomics 2003)
    3. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2 Nagase T.... Nomura N. (DNA Res. 1996)
    4. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    8. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    9. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23510 HGNC: 21294 AceView: KCTD2 Ensembl:ENSG00000180901 euGenes: HUgn23510
    ECgene: KCTD2 H-InvDB: KCTD2

    (According to HUGE)
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    HUGE: KIAA0176

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for KCTD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KCTD2 gene:
    Search GeneIP for patents involving KCTD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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