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Aliases for KCTD19 Gene

Aliases for KCTD19 Gene

  • Potassium Channel Tetramerization Domain Containing 19 2 3
  • Potassium Channel Tetramerisation Domain Containing 19 2

External Ids for KCTD19 Gene

Previous GeneCards Identifiers for KCTD19 Gene

  • GC16M065881
  • GC16U900651
  • GC16M067323
  • GC16M053196

Summaries for KCTD19 Gene

GeneCards Summary for KCTD19 Gene

KCTD19 (Potassium Channel Tetramerization Domain Containing 19) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCTD19 Gene

Genomics for KCTD19 Gene

Regulatory Elements for KCTD19 Gene

Genomic Location for KCTD19 Gene

67,289,428 bp from pter
67,326,763 bp from pter
37,336 bases
Minus strand

Genomic View for KCTD19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KCTD19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KCTD19 Gene

Proteins for KCTD19 Gene

  • Protein details for KCTD19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BTB/POZ domain-containing protein KCTD19
    Protein Accession:
    Secondary Accessions:
    • B4DZ49
    • Q8N804

    Protein attributes for KCTD19 Gene

    926 amino acids
    Molecular mass:
    104938 Da
    Quaternary structure:
    • Identified in a complex with ZNF541, HDAC1 and HSPA2.

neXtProt entry for KCTD19 Gene

Proteomics data for KCTD19 Gene at MOPED

Post-translational modifications for KCTD19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KCTD19 Gene

No data available for DME Specific Peptides for KCTD19 Gene

Domains for KCTD19 Gene

Protein Domains for KCTD19 Gene


Suggested Antigen Peptide Sequences for KCTD19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 BTB (POZ) domains.
  • Contains 2 BTB (POZ) domains.
genes like me logo Genes that share domains with KCTD19: view

No data available for Gene Families for KCTD19 Gene

Function for KCTD19 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KCTD19 Gene

Localization for KCTD19 Gene

Subcellular locations from

Jensen Localization Image for KCTD19 Gene COMPARTMENTS Subcellular localization image for KCTD19 gene
Compartment Confidence
nucleus 3
cytosol 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KCTD19 Gene

Pathways for KCTD19 Gene

SuperPathways for KCTD19 Gene

No Data Available

Interacting Proteins for KCTD19 Gene

Gene Ontology (GO) - Biological Process for KCTD19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051260 protein homooligomerization IEA --
genes like me logo Genes that share ontologies with KCTD19: view

No data available for Pathways by source for KCTD19 Gene

Transcripts for KCTD19 Gene

Unigene Clusters for KCTD19 Gene

Potassium channel tetramerisation domain containing 19:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KCTD19

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KCTD19 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^
SP1: - - - - - - - -
SP2: - - -
SP3: - - -
SP5: - - - - - -
SP6: - - - - - - -
SP7: - - -
SP8: -
SP9: -

ExUns: 15a · 15b

Relevant External Links for KCTD19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KCTD19 Gene

mRNA expression in normal human tissues for KCTD19 Gene

mRNA differential expression in normal tissues according to GTEx for KCTD19 Gene

This gene is overexpressed in Testis (47.0).

Protein differential expression in normal tissues for KCTD19 Gene

This gene is overexpressed in Plasma (63.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for KCTD19 Gene

SOURCE GeneReport for Unigene cluster for KCTD19 Gene Hs.299127

genes like me logo Genes that share expressions with KCTD19: view

Expression partners for KCTD19 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for KCTD19 Gene

Orthologs for KCTD19 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KCTD19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KCTD19 35
  • 88.94 (n)
  • 89.62 (a)
KCTD19 36
  • 89 (a)
(Canis familiaris)
Mammalia KCTD19 35
  • 89.97 (n)
  • 90.91 (a)
KCTD19 36
  • 90 (a)
(Mus musculus)
Mammalia Kctd19 35
  • 86.63 (n)
  • 88.97 (a)
Kctd19 16
Kctd19 36
  • 87 (a)
(Pan troglodytes)
Mammalia KCTD19 35
  • 99.6 (n)
  • 99.68 (a)
KCTD19 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Kctd19 35
  • 86.88 (n)
  • 89.62 (a)
(Monodelphis domestica)
Mammalia KCTD19 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 50 (a)
-- 36
  • 58 (a)
-- 36
  • 52 (a)
(Gallus gallus)
Aves KCTD19 35
  • 63.87 (n)
  • 59.41 (a)
KCTD19 36
  • 50 (a)
(Anolis carolinensis)
Reptilia KCTD19 36
  • 48 (a)
Species with no ortholog for KCTD19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for KCTD19 Gene

Gene Tree for KCTD19 (if available)
Gene Tree for KCTD19 (if available)

Paralogs for KCTD19 Gene

(5) SIMAP similar genes for KCTD19 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with KCTD19: view

No data available for Paralogs for KCTD19 Gene

Variants for KCTD19 Gene

Sequence variations from dbSNP and Humsavar for KCTD19 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs27860 -- 67,291,054(-) TCCCC(A/G)CTCTG intron-variant
rs809224 -- 67,297,205(-) ACAGC(A/C)ATGCA intron-variant
rs813300 -- 67,314,148(-) tgggc(A/C)cggtg intron-variant
rs1613219 -- 67,300,848(+) catgt(G/T)ggcca intron-variant
rs1645857 -- 67,317,358(+) cctgt(A/T)atcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KCTD19 Gene

Variant ID Type Subtype PubMed ID
dgv2885n71 CNV Loss 21882294
dgv2886n71 CNV Loss 21882294
nsv524363 CNV Loss 19592680
nsv906803 CNV Loss 21882294
nsv522852 CNV Gain 19592680
nsv524492 CNV Loss 19592680
nsv471092 CNV Gain 18288195

Relevant External Links for KCTD19 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCTD19 Gene

Disorders for KCTD19 Gene

Relevant External Links for KCTD19

Genetic Association Database (GAD)

No disorders were found for KCTD19 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for KCTD19 Gene

Publications for KCTD19 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for KCTD19 Gene

Sources for KCTD19 Gene

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