Aliases for KCTD17 Gene
External Ids for KCTD17 Gene
Previous GeneCards Identifiers for KCTD17 Gene
GeneCards Summary for KCTD17 Gene
KCTD17 (Potassium Channel Tetramerization Domain Containing 17) is a Protein Coding gene. Diseases associated with KCTD17 include dystonia 26, myoclonic. GO annotations related to this gene include identical protein binding. An important paralog of this gene is KCTD5.
UniProtKB/Swiss-Prot for KCTD17 Gene
Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).