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Aliases for KCTD17 Gene

Aliases for KCTD17 Gene

  • Potassium Channel Tetramerization Domain Containing 17 2 3
  • Potassium Channel Tetramerisation Domain Containing 17 2

External Ids for KCTD17 Gene

Previous GeneCards Identifiers for KCTD17 Gene

  • GC22P035773
  • GC22P037447
  • GC22P020413

Summaries for KCTD17 Gene

GeneCards Summary for KCTD17 Gene

KCTD17 (Potassium Channel Tetramerization Domain Containing 17) is a Protein Coding gene. GO annotations related to this gene include identical protein binding. An important paralog of this gene is KCTD5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCTD17 Gene

Genomics for KCTD17 Gene

Regulatory Elements for KCTD17 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KCTD17 Gene

37,051,736 bp from pter
37,063,390 bp from pter
11,655 bases
Plus strand

Genomic View for KCTD17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KCTD17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KCTD17 Gene

Proteins for KCTD17 Gene

  • Protein details for KCTD17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    BTB/POZ domain-containing protein KCTD17
    Protein Accession:
    Secondary Accessions:
    • B0QYA9
    • B0QYB0
    • O95517

    Protein attributes for KCTD17 Gene

    321 amino acids
    Molecular mass:
    35670 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH25403.1; Type=Miscellaneous discrepancy; Note=The sequence differs in the N-terminus for unknown reasons.; Evidence={ECO:0000305}; Sequence=AAH31038.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KCTD17 Gene


neXtProt entry for KCTD17 Gene

Proteomics data for KCTD17 Gene at MOPED

Post-translational modifications for KCTD17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KCTD17 Gene

Domains for KCTD17 Gene

Protein Domains for KCTD17 Gene

Suggested Antigen Peptide Sequences for KCTD17 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 BTB (POZ) domain.
  • Contains 1 BTB (POZ) domain.
genes like me logo Genes that share domains with KCTD17: view

No data available for Gene Families for KCTD17 Gene

Function for KCTD17 Gene

Gene Ontology (GO) - Molecular Function for KCTD17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0042802 identical protein binding IPI 16189514
genes like me logo Genes that share ontologies with KCTD17: view

Phenotypes for KCTD17 Gene

GenomeRNAi human phenotypes for KCTD17:
genes like me logo Genes that share phenotypes with KCTD17: view

Animal Model Products

miRNA for KCTD17 Gene

miRTarBase miRNAs that target KCTD17

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KCTD17

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for KCTD17 Gene

Localization for KCTD17 Gene

Subcellular locations from

Jensen Localization Image for KCTD17 Gene COMPARTMENTS Subcellular localization image for KCTD17 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KCTD17 Gene

Pathways for KCTD17 Gene

SuperPathways for KCTD17 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KCTD17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051260 protein homooligomerization IEA --
genes like me logo Genes that share ontologies with KCTD17: view

No data available for Pathways by source for KCTD17 Gene

Transcripts for KCTD17 Gene

Unigene Clusters for KCTD17 Gene

Potassium channel tetramerisation domain containing 17:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KCTD17

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KCTD17 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
SP1: - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - - - - - - -
SP5: - -
SP8: -

Relevant External Links for KCTD17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KCTD17 Gene

mRNA expression in normal human tissues for KCTD17 Gene

mRNA differential expression in normal tissues according to GTEx for KCTD17 Gene

This gene is overexpressed in Brain - Putamen (basal ganglia) (6.2) and Brain - Caudate (basal ganglia) (4.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for KCTD17 Gene

SOURCE GeneReport for Unigene cluster for KCTD17 Gene Hs.517597

genes like me logo Genes that share expressions with KCTD17: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for KCTD17 Gene

Orthologs for KCTD17 Gene

This gene was present in the common ancestor of animals.

Orthologs for KCTD17 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KCTD17 35
  • 94.11 (n)
  • 98.34 (a)
KCTD17 36
  • 84 (a)
(Canis familiaris)
Mammalia KCTD17 35
  • 90.77 (n)
  • 90.96 (a)
KCTD17 36
  • 79 (a)
(Mus musculus)
Mammalia Kctd17 35
  • 88.66 (n)
  • 91.5 (a)
Kctd17 16
Kctd17 36
  • 80 (a)
(Pan troglodytes)
Mammalia KCTD17 35
  • 99.79 (n)
  • 100 (a)
KCTD17 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Kctd17 35
  • 91.55 (n)
  • 97.18 (a)
(Monodelphis domestica)
Mammalia KCTD17 36
  • 72 (a)
(Gallus gallus)
Aves KCTD17 35
  • 82.69 (n)
  • 93.92 (a)
KCTD17 36
  • 76 (a)
(Anolis carolinensis)
Reptilia KCTD17 36
  • 89 (a)
(Danio rerio)
Actinopterygii LOC568267 35
  • 71.64 (n)
  • 79.56 (a)
KCTD17 36
  • 54 (a)
fruit fly
(Drosophila melanogaster)
Insecta inc 36
  • 56 (a)
(Caenorhabditis elegans)
Secernentea inso-1 36
  • 38 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8310 36
  • 59 (a)
Species with no ortholog for KCTD17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for KCTD17 Gene

Gene Tree for KCTD17 (if available)
Gene Tree for KCTD17 (if available)

Paralogs for KCTD17 Gene

Paralogs for KCTD17 Gene

(7) SIMAP similar genes for KCTD17 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with KCTD17: view

Variants for KCTD17 Gene

Sequence variations from dbSNP and Humsavar for KCTD17 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs710183 -- 37,054,720(-) ccagg(A/C)actga intron-variant
rs710184 -- 37,057,219(+) CTGGT(A/G)AATGC intron-variant
rs710185 -- 37,057,412(+) AAGCA(C/T)GTGTA reference, synonymous-codon
rs855792 -- 37,059,645(-) CTGGG(A/G)ATGCT intron-variant
rs855793 -- 37,053,568(-) ACTGC(A/G)TTCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KCTD17 Gene

Variant ID Type Subtype PubMed ID
nsv834187 CNV Loss 17160897
esv34015 CNV Loss 18971310
nsv459882 CNV Gain 19166990
nsv829203 CNV Loss 20364138
dgv4960n71 CNV Loss 21882294
nsv915015 CNV Loss 21882294

Relevant External Links for KCTD17 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCTD17 Gene

Disorders for KCTD17 Gene

Relevant External Links for KCTD17

Genetic Association Database (GAD)

No disorders were found for KCTD17 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for KCTD17 Gene

Publications for KCTD17 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3

Products for KCTD17 Gene

Sources for KCTD17 Gene

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