Aliases for KCTD17 Gene
External Ids for KCTD17 Gene
Previous GeneCards Identifiers for KCTD17 Gene
GeneCards Summary for KCTD17 Gene
KCTD17 (Potassium Channel Tetramerization Domain Containing 17) is a Protein Coding gene. Diseases associated with KCTD17 include dystonia 26, myoclonic and dystonia. GO annotations related to this gene include identical protein binding. An important paralog of this gene is KCTD5.
UniProtKB/Swiss-Prot for KCTD17 Gene
Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).