Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



KCTD16 Gene

protein-coding   GIFtS: 47
GCID: GC05P143565

Potassium Channel Tetramerization Domain Containing 16

(Previous name: potassium channel tetramerisation domain containing 16)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Potassium Channel Tetramerization Domain Containing 161 2
Potassium Channel Tetramerisation Domain Containing 161 2
Potassium Channel Tetramerization Domain-Containing Protein 162 3
KIAA13173 5
BTB/POZ Domain-Containing Protein KCTD162

External Ids:    HGNC: 292441   Entrez Gene: 575282   Ensembl: ENSG000001837757   OMIM: 6134235   UniProtKB: Q68DU83   

Export aliases for KCTD16 gene to outside databases

Previous GC identifers: GC05P143613 GC05P138699


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for KCTD16 Gene:
KCTD16 (potassium channel tetramerization domain containing 16) is a protein-coding gene. An important paralog of this gene is KCTD1.

UniProtKB/Swiss-Prot: KCD16_HUMAN, Q68DU8
Function: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor
response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating
onset and promoting desensitization (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_029289.12  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCTD16 gene promoter:
         RP58   Nkx2-5   GATA-1   HNF-1A   SRY   POU2F1   HNF-1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCTD16 promoter sequence
   Search Chromatin IP Primers for KCTD16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCTD16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q32

KCTD16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD16 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P143565:  view genomic region     (about GC identifiers)

Start:
143,550,396 bp from pter      End:
143,865,249 bp from pter
Size:
314,854 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: KCD16_HUMAN, Q68DU8 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein KCTD16  
Size: 428 amino acids; 49138 Da
Subunit: Interacts as a tetramer with GABRB1 and GABRB2 (By similarity)
Sequence caution: Sequence=BAA92555.1; Type=Erroneous initiation;
Secondary accessions: Q9P2M9

Explore the universe of human proteins at neXtProt for KCTD16: NX_Q68DU8

Explore proteomics data for KCTD16 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KCTD16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065819.1  
    ENSEMBL proteins: 
     ENSP00000424151   ENSP00000426548  

    KCTD16 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for KCTD16
    OriGene Protein Over-expression Lysate for KCTD16
    OriGene MassSpec for KCTD16
    OriGene Custom Protein Services for KCTD16
    GenScript Custom Purified and Recombinant Proteins Services for KCTD16
    Novus Biologicals KCTD16 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KCTD16

     
    Search eBioscience for Proteins for KCTD16 

     
    antibodies-online proteins for KCTD16 (2 products) 

     
    antibodies-online peptides for KCTD16

    KCTD16 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for KCTD16
    Novus Biologicals KCTD16 Antibodies
    Abcam antibodies for KCTD16
    Cloud-Clone Corp. Antibodies for KCTD16
    Search ThermoFisher Antibodies for KCTD16
    LSBio Antibodies in human, mouse, rat for KCTD16
    antibodies-online antibodies for KCTD16 (9 products) 

    KCTD16 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for KCTD16
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for KCTD16
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KCTD16
    Cloud-Clone Corp. CLIAs for KCTD16
    Search eBioscience for ELISAs for KCTD16 
    antibodies-online kits for KCTD16 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    IUPHAR Guide to PHARMACOLOGY protein family classification: KCTD16


    3 InterPro protein domains:
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR003131 T1-type_BTB

    Graphical View of Domain Structure for InterPro Entry Q68DU8

    ProtoNet protein and cluster: Q68DU8

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: KCD16_HUMAN, Q68DU8
    Similarity: Contains 1 BTB (POZ) domain


    Find genes that share domains with KCTD16           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCD16_HUMAN, Q68DU8
    Function: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor
    response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating
    onset and promoting desensitization (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KCTD16           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for KCTD16:
     Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCTD16
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KCTD16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KCTD16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KCTD16

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat KCTD16 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD16 (see all 40):
    hsa-miR-124* hsa-miR-1321 hsa-let-7d hsa-miR-199a-3p hsa-miR-218 hsa-let-7g hsa-miR-3122 hsa-miR-3658
    SwitchGear 3'UTR luciferase reporter plasmidKCTD16 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KCTD16
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD16

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KCTD16

    Clone
    Products:
         
    OriGene clones in human, mouse for KCTD16 (see all 7)
    OriGene ORF clones in mouse, rat for KCTD16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KCTD16 (NM_020768)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD16

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KCTD16
    Browse ESI BIO Cell Lines and PureStem Progenitors for KCTD16 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD16


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    KCD16_HUMAN, Q68DU8: Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell
    membrane (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    plasma membrane3
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030054cell junction IEA--
    GO:0042734presynaptic membrane IEA--
    GO:0043235receptor complex IEA--
    GO:0045211postsynaptic membrane IEA--

    Find genes that share ontologies with KCTD16           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KCTD16
    Interactions:

        Search GeneGlobe Interaction Network for KCTD16

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008277regulation of G-protein coupled receptor protein signaling pathway IEA--
    GO:0051260protein homooligomerization IEA--

    Find genes that share ontologies with KCTD16           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KCTD16 (KCD16)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for KCTD16 gene: 
    NM_020768.3  

    Unigene Cluster for KCTD16:

    Potassium channel tetramerisation domain containing 16
    Hs.661870  [show with all ESTs]
    Unigene Representative Sequence: AB037738
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000512467 ENST00000507359(uc003lnm.1 uc003lnn.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KCTD16 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD16 (see all 40):
    hsa-miR-124* hsa-miR-1321 hsa-let-7d hsa-miR-199a-3p hsa-miR-218 hsa-let-7g hsa-miR-3122 hsa-miR-3658
    SwitchGear 3'UTR luciferase reporter plasmidKCTD16 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KCTD16
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD16
    Clone
    Products:
         
    OriGene clones in human, mouse for KCTD16 (see all 7)
    OriGene ORF clones in mouse, rat for KCTD16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KCTD16 (NM_020768)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD16
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KCTD16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD16
      QuantiTect SYBR Green Assays in human, mouse, rat KCTD16
      QuantiFast Probe-based Assays in human, mouse, rat KCTD16

    Additional mRNA sequence: 

    AB037738.1 AK292477.1 BC111962.1 BC113435.1 CR749266.1 

    2 DOTS entries:

    DT.120808583  DT.40251046 

    4 AceView cDNA sequences:

    AA332022 AL120401 AB037738 CR749266 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    KCTD16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCAGCAAAA
    KCTD16 Expression
    About this image


    KCTD16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Lung (Respiratory System)
             Trachea
     
     Eye (Sensory Organs)
             Retina
     
     Neural Tube (Nervous System)
             Spinal Ventral Columns
     
     Brain (Nervous System)
             Medulla Oblongata
    KCTD16 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KCTD16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.661870
        Custom PCR Arrays for KCTD16
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for KCTD16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD16
    QuantiTect SYBR Green Assays in human, mouse, rat KCTD16
    QuantiFast Probe-based Assays in human, mouse, rat KCTD16
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for KCTD16 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kctd161 , 5 potassium channel tetramerisation domain containing more1, 5 89.7(n)1
    96.49(a)1
      18 (21.30 cM)5
    3833481  NM_026135.11  NP_080411.11 
     402583615 
    chicken
    (Gallus gallus)
    Aves KCTD161 potassium channel tetramerisation domain containing more 81.3(n)
    90.14(a)
      427644  XM_425217.3  XP_425217.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    90(a)
    84(a)
    many → 1
    many → 1
    GL343234.1(1807046-1807556)
    GL343234.1(2084281-2085552)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.130022 Xenopus laevis transcribed sequences 76.23(n)    BJ095666.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kctd16b1 potassium channel tetramerisation domain containing more 70.18(n)
    76.79(a)
      569756  NM_001128752.1  NP_001122224.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG108306
    --
    50(a)
    1 → many
    3R(16720174-16723042)
    worm
    (Caenorhabditis elegans)
    Secernentea VM106R.16
    Protein VM106R.1 (VM106R.1) mRNA, complete cds
    37(a)
    many ↔ many
    II(10827716-10829556) WBGene00014848


    ENSEMBL Gene Tree for KCTD16 (if available)
    TreeFam Gene Tree for KCTD16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for KCTD16 gene
    KCTD12  KCTD82  KCTD152  KCTD42  KCTD112  KCNRG2  KCTD122  KCTD212  
    KCTD62  KCTD142  
    2 SIMAP similar genes for KCTD16 using alignment to 1 protein entry:     KCD16_HUMAN:
    KCTD8    KCTD12

    Find genes that share paralogs with KCTD16           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for KCTD16 (see all 5493)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1433567941,2
    Cuntested1143586716(+) GAAGCA/GACACA 2 N D mis10--------
    rs1829259391,2
    --143552306(+) CCTAAA/TTCAGT 1 -- int10--------
    rs1876209431,2
    --143552395(+) AATCCA/TTCATT 1 -- int10--------
    rs1415407981,2
    --143552484(+) AAAAAG/TGATAT 1 -- int10--------
    rs1926008031,2
    --143552577(+) GAATGC/TGTATA 1 -- int10--------
    rs1842529341,2
    --143552632(+) AGTGTG/TGCGAA 1 -- int10--------
    rs1896110561,2
    --143552725(+) CTATCA/GTAACT 1 -- int10--------
    rs750476881,2
    C,F--143552726(+) TACCAC/TGAAAA 1 -- int13Minor allele frequency- T:0.25NA 8
    rs1926902561,2
    --143552732(+) AACTAC/TGCATG 1 -- int10--------
    rs1145325661,2
    F--143552790(+) AGCAAC/TTTAAA 1 -- int11Minor allele frequency- T:0.01NA 120

    HapMap Linkage Disequilibrium report for KCTD16 (143550396 - 143800396 bp, first 250kb of KCTD16)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for KCTD16:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1047e199CNV Deletion23128226
    esv2730867CNV Deletion23290073
    esv2207447CNV Deletion18987734
    nsv5046CNV Insertion18451855
    esv273840CNV Insertion20981092
    nsv5045CNV Insertion18451855
    esv271239CNV Insertion20981092
    nsv882997CNV Gain21882294
    nsv830513CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KCTD16
    DNA2.0 Custom Variant and Variant Library Synthesis for KCTD16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613423    OMIM disorders: --


    Find genes that share disorders with KCTD16           About GenesLikeMe

    Genetic Association Database (GAD): KCTD16
    Human Genome Epidemiology (HuGE) Navigator: KCTD16 (1 document)

    Export disorders for KCTD16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for KCTD16 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with KCTD16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 57528 HGNC: 29244 AceView: KCTD16 Ensembl:ENSG00000183775 euGenes: HUgn57528
    ECgene: KCTD16 H-InvDB: KCTD16

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1317

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for KCTD16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for KCTD16 gene:
    Search GeneIP for patents involving KCTD16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KCTD16  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for KCTD16  
     OriGene MassSpec for KCTD16   OriGene clones in human, mouse for KCTD16  
     OriGene qSTAR qPCR primer pairs in human, mouse for KCTD16   OriGene Purified Protein for KCTD16  
     OriGene ORF clones in mouse, rat for KCTD16   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for KCTD16   OriGene Custom Protein Services for KCTD16  

     
     
     Block miRNA regulation of human, mouse, rat KCTD16 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing KCTD16
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCTD16 Predesigned siRNA for gene silencing in human, mouse, rat KCTD16
     QuantiFast Probe-based Assays in human, mouse, rat KCTD16 QuantiTect SYBR Green Assays in human, mouse, rat KCTD16
     Custom PCR Arrays for KCTD16 Search Chromatin IP Primers for KCTD16
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD16  Search GeneGlobe Interaction Network for KCTD16
     Regulatory tfbs in KCTD16 promoter
     GenScript Custom Purified and Recombinant Proteins Services for KCTD16 GenScript cDNA clones with any tag delivered in your preferred vector for KCTD16
     GenScript Custom Assay Services for KCTD16 GenScript Custom overexpressing Cell Line Services for KCTD16
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for KCTD16 (KCD16)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     KCTD16 antibodies
     KCTD16 lysates
     Antibodies for KCTD16
     See all of Abcam's Antibodies, Kits and Proteins for KCTD16
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for KCTD16
     Antibodies for KCTD16
     ELISAs for KCTD16
     CLIAs for KCTD16



     Browse ESI BIO Cell Lines and PureStem Progenitors for KCTD16
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD16
     SwitchGear 3'UTR luciferase reporter plasmids for KCTD16
     SwitchGear Promoter luciferase reporter plasmids for KCTD16
     Search ThermoFisher Antibodies for KCTD16
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD16
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCTD16
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KCTD16
     LSBio Antibodies in human, mouse, rat for KCTD16
     Browse compounds at ApexBio
     Search Addgene for plasmids for KCTD16
      Search eBioscience for proteins for KCTD16
      Search eBioscience for elisas for KCTD16
      eBioscience FlowRNA Probe Sets
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     antibodies-online antibodies for KCTD16 (9 products)
     antibodies-online kits for KCTD16 (4 products)
     antibodies-online peptides for KCTD16
     antibodies-online proteins for KCTD16 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      KCTD16 gene at Home site.
    Version: 3.12.234 23 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4