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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

KCTD15 Gene

protein-coding GIFtS: 52
GCID: GC19P034287

potassium channel tetramerisation domain containing 15

Explore 6 diseases affiliated with
KCTD15 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Potassium Channel Tetramerisation Domain Containing 15¹ ²
MGC25497¹
BTB/POZ Domain-Containing Protein KCTD15²

External Ids:	HGNC: 23297¹	Entrez Gene: 79047²	Ensembl: ENSG00000153885⁷	UniProtKB: Q96SI1³

Export aliases for KCTD15 gene to outside databases

Previous GC identifers: GC19P038979 GC19P030786

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for KCTD15

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the KCTD15 gene promoter:
MEF-2A SRF TBP SRF (504 AA) IRF-7A aMEF-2 Tal-1beta En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KCTD15 promoter sequence

Search SABiosciences Chromatin IP Primers for KCTD15

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCTD15

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.11 Ensembl cytogenetic band: 19q13.11 HGNC cytogenetic band: 19q13.12

KCTD15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD15 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P034287: view genomic region (about GC identifiers)

Start:	34,286,838 bp from pter	End:	34,306,666 bp from pter
Size:	19,829 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KCD15_HUMAN, Q96SI1 (See protein sequence)

Recommended Name: BTB/POZ domain-containing protein KCTD15

Size: 283 amino acids; 31942 Da

Secondary accessions: A8K600 Q9BVI6

Alternative splicing: 2 isoforms: Q96SI1-1 Q96SI1-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KCTD15: NX_Q96SI1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96SI1

KCTD15 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001123466.1 NP_001123467.1 NP_076981.2

ENSEMBL proteins:

ENSP00000466357 ENSP00000466804 ENSP00000467955 ENSP00000464722 ENSP00000467612

ENSP00000284006 ENSP00000464812 ENSP00000467353 ENSP00000394390

Human Recombinant Protein Products:

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	Browse recombinant and purified proteins available from Enzo Life Sciences
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	Novus Biologicals KCTD15 Proteins Novus Biologicals KCTD15 Lysates
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	Uscn Proteins for KCTD15

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	ThermoFisher Antibodies for KCTD15

Assay Products for KCTD15:

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	GenScript Custom Assay Services for KCTD15
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for KCTD15

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

KCTD15 for domains About GeneDecksing

3 InterPro domains/families:

IPR000210 BTB/POZ-like

IPR011333 BTB/POZ_fold

IPR003131 T1-type_BTB

Graphical View of Domain Structure for InterPro Entry Q96SI1

ProtoNet protein and cluster: Q96SI1

1 Blocks protein family: IPB000210 BTB/POZ domain

UniProtKB/Swiss-Prot: KCD15_HUMAN, Q96SI1

Similarity: Contains 1 BTB (POZ) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 3): KCTD15 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KCTD15
		8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate KCTD15 (see all 67):
		hsa-miR-631 hsa-miR-300 hsa-miR-146a hsa-miR-298 hsa-miR-629 hsa-miR-200b hsa-miR-4324 hsa-miR-455-5p

		SwitchGear 3'UTR luciferase reporter plasmid: KCTD15 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCTD15 (see all 7) OriGene shRNA RFP: KCTD15 OriGene siRNA: KCTD15
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCTD15

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for KCTD15

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCTD15 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCTD15 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): KCTD15 (NM_024076)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD15
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD15

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for KCTD15
		Search LifeMap BioReagents cell lines for KCTD15

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD15

1 GenomeRNAi human phenotype for KCTD15:

Decreased viability

Animal Models:
1 MGI phenotypic allele

for Kctd15 (no phenotypes)

KCTD15 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Sweet Taste Signaling

Sweet Taste Signaling	1.00	Bitter Taste Signaling	0.44
Melatonin Signaling	0.72	Sperm Motility	0.36
Cellular Effects of Sildenafil	0.46

Activation of cAMP-Dependent PKA

	Activation of cAMP-Dependent PKA	1.00			PKA Signaling	0.56
	cAMP Pathway	0.77

Neuropathic Pain-Signaling in Dorsal Horn Neurons

	Neuropathic Pain-Signaling in Dorsal Horn Neurons	1.00			Cholera Infection	0.40
	Aldosterone Signaling in Epithelial Cells	0.47

Hepatic ABC Transporters

Hepatic ABC Transporters

1.00

MODY (Maturity-Onset Diabetes of Young)

0.41

5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KCTD15 (see all 13)

	Cholera Infection
	Neuropathic Pain-Signaling in Dorsal Horn Neurons
	Hepatic ABC Transporters
	PKA Signaling
	Sweet Taste Signaling

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for KCTD15

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5/9 Interacting proteins for KCTD15 (Q96SI1^{2, 3} ENSP00000394390⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
REN	P00797²^,³, ENSP00000272190⁴	MINT-65369 I2D: score=5 STRING: ENSP00000272190
WIPI1	Q5MNZ9²^,³	MINT-65371 I2D: score=5
ENSA	O43768²^,³	MINT-65372 I2D: score=4
TRIM27	P14373²^,³	MINT-65370 I2D: score=4
TERF1	P54274³, ENSP00000276603⁴	I2D: score=1 STRING: ENSP00000276603

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0051260	protein homooligomerization	IEA	--

KCTD15 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KCTD15
Search CenterWatch for drugs/clinical trials and news about KCTD15 / KCD15

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for KCTD15 gene (3 alternative transcripts):

NM_001129994.1 NM_001129995.1 NM_024076.2

Unigene Cluster for KCTD15:

Potassium channel tetramerisation domain containing 15

Hs.221873 [show with all ESTs]

Unigene Representative Sequence: NM_024076

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000587658 ENST00000587559 ENST00000588637 ENST00000590771 ENST00000589786

ENST00000284006(uc002nuv.3 uc002nuy.4 uc010xrt.2 uc002nux.4)

ENST00000588881 ENST00000590906 ENST00000430256(uc002nuw.4) ENST00000592210

ENST00000590385 ENST00000592363

miRNA Products:		OriGene 3'-UTR Clone (see all 3): KCTD15 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KCTD15
		8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate KCTD15 (see all 67):
		hsa-miR-631 hsa-miR-300 hsa-miR-146a hsa-miR-298 hsa-miR-629 hsa-miR-200b hsa-miR-4324 hsa-miR-455-5p

		SwitchGear 3'UTR luciferase reporter plasmid: KCTD15 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCTD15 (see all 7) OriGene shRNA RFP: KCTD15 OriGene siRNA: KCTD15
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCTD15

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCTD15 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCTD15 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCTD15 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat KCTD15
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCTD15
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCTD15

Additional cDNA sequence:

AK025590.1 AK027901.1 AK096843.1 AK225793.1 AK291465.1 AK294543.1 BC001185.1 BC009335.2

8 DOTS entries:

DT.453844 DT.92427113 DT.97777800 DT.95264141 DT.121498397 DT.121498402 DT.40121488 DT.121498404

24/169 AceView cDNA sequences (see all 169):

AW510640 N31532 AA425927 AA331978 BU175567 CA950056 BM840722 BG571742

BG677356 AA461228 AI498644 BF061821 AI263714 BU158268 BM834184 AI803386

AI992053 AI827822 CA943857 AI808997 AW959399 BE312560 AI989791 CA397552

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for KCTD15 (see all 9) About this scheme

ExUns:	1	^	2a	·	2b	^	3a	·	3b	·	3c	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	·	9c	·	9d	^	10	^	11a	·	11b
SP1:													-		-		-				-
SP2:																					-																				-
SP3:			-		-		-		-		-		-		-		-				-
SP4:							-		-		-		-		-		-				-
SP5:							-		-		-		-		-		-

ECgene alternative splicing isoforms for KCTD15

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

KCTD15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAAAGCTTC

About this image

KCTD15 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor T42 (Embryonic Progenitor Cell)

PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See KCTD15 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KCTD15

SOURCE GeneReport for Unigene cluster: Hs.221873

SABiosciences Custom PCR Arrays for KCTD15

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCTD15 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCTD15

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD15

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for KCTD15 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	KCTD15¹	potassium channel tetramerisation domain containing more	75.38(n) 91.92(a)		415779 XM_414140.3 XP_414140.3
lizard (Anolis carolinensis)	Reptilia	KCTD15⁶	--	90(a)	1 ↔ 1	GL343508.1(99631-150160)
tropical clawed frog (Xenopus tropicalis)	Amphibia	MGC76138²	hypothetical protein MGC76138	77.25(n)		BC063913.1
zebrafish (Danio rerio)	Actinopterygii	Dr.15592²	Transcribed sequence with moderate similarity to protein more	76.08(n)		BM342205.1
fruit fly (Drosophila melanogaster)	Insecta	CG10440¹	CG10440	60.71(n) 54.89(a)		37456 NM_137744.1 NP_611588.1

ENSEMBL Gene Tree for KCTD15 (if available)
TreeFam Gene Tree for KCTD15 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for KCTD15 gene

KCTD1² KCTD8² KCTD16² KCTD4² KCNRG² KCTD11² KCTD12² KCTD21²

KCTD6² KCTD14²

4 SIMAP similar genes for KCTD15 using alignment to 6 protein entries: KCD15_HUMAN (see all proteins):

KCTD1 KCTD21 KCTD6 KCTD19

KCTD15 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs148831611^1,2		--	34285813(+)	`ACGCGC/TAGAGA`	3	--	us2k¹		0	--	--	--	--
rs3810361^1,2	C,F,H,	--	34285951(-)	`AAAGAA/GGCCCT`	3	--	us2k¹		21		NS EA WA NA CSA	2343
rs183201520^1,2		--	34286025(+)	`TTTGTA/GAGCTA`	3	--	us2k¹		0	--	--	--	--
rs143440807^1,2		--	34286249(+)	`GCGAGA/GTCCTC`	3	--	us2k¹		0	--	--	--	--
rs115919410^1,2	F,	--	34286516(+)	`GCGCTC/TCGTTT`	3	--	us2k¹		1		WA	118
rs187845213^1,2		--	34286572(+)	`GCGGGA/GCGCAA`	3	--	us2k¹		0	--	--	--	--
rs285677^1,2	C,F,	--	34286666(-)	`CCCGGG/ACGCCC`	3	--	us2k¹		6		NA CSA WA EA	363
rs192954952^1,2		--	34286722(+)	`CGCGCC/TGCGCG`	3	--	us2k¹		0	--	--	--	--
rs113234981^1,2	C,	--	34286841(+)	`GCGGGG/TCAGAG`	3	--	us2k¹		1		NA	2
rs184976950^1,2		--	34286889(+)	`CCTGGA/CCCCCG`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for KCTD15 (34286838 - 34306666 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for KCTD15
4 CNVs: 8871 78167 3188 4076

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCTD15

DNA2.0 Custom Variant and Variant Library Synthesis for KCTD15

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KCTD15 for disorders About GeneDecksing

6 diseases for KCTD15: About MalaCards

type 2 diabetes mellitus anorexia nervosa diabetes mellitus asthma

obesity neuronitis

Human Genome Epidemiology (HuGE) Navigator: KCTD15 (23 documents)

Export disorders for KCTD15 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for KCTD15 gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with KCTD15)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)¹ Tatham M.H....Hay R.T. (2011)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)¹ Speliotes E.K....Loos R.J. (2010)
Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide assoc iation studies. (PubMed id 20724581)¹ den Hoed M....Loos R.J. (2010)
Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. (PubMed id 20520848)¹ Elks C.E....Ong K.K. (2010)
Evaluating the discriminative power of multi-trait ge netic risk scores for type 2 diabetes in a northern Swedish population. (PubMed id 20571754)¹ Fontaine-Bisson B....Franks P.W. (2010)
Implication of genetic variants near NEGR1, SEC16B, T MEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, a nd KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)¹ Ng M.C....Ma R.C. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 79047	HGNC: 23297	AceView: KCTD15	Ensembl:ENSG00000153885	euGenes: HUgn79047
ECgene: KCTD15	H-InvDB: KCTD15

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for KCTD15	Pharmacogenomics, SNPs, Pathways

Intellectual Property for KCTD15 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for KCTD15 gene:
Search GeneIP for patents involving KCTD15

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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KCTD15 Gene

potassium channel tetramerisation domain containing 15

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KCTD15 Gene

potassium channel tetramerisation domain containing 15

Aliasesfor KCTD15 gene

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Genomic Viewsfor KCTD15 gene

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Protein Domains /Familiesfor KCTD15 gene

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External Searches for KCTD15 gene

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Specialized Databases showing KCTD15 gene

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for KCTD15 gene

Genomic Views
for KCTD15 gene

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for KCTD15 gene

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Families
for KCTD15 gene

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for KCTD15 gene

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for KCTD15 gene

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for KCTD15 gene

Transcripts
for KCTD15 gene

Expression
for KCTD15 gene

Orthologs
for KCTD15 gene

Paralogs
for KCTD15 gene

Genomic Variants
for KCTD15 gene

Disorders / Diseases
for KCTD15 gene

Publications
for KCTD15 gene

Intellectual Property
for KCTD15 gene

Products
for KCTD15 gene