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KCTD15 Gene

protein-coding   GIFtS: 55
GCID: GC19P034287

Potassium Channel Tetramerization Domain Containing 15

(Previous name: potassium channel tetramerisation domain containing 15)
  Search for KCTD15
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Potassium Channel Tetramerization Domain Containing 151 2
Potassium Channel Tetramerisation Domain Containing 151 2
Potassium Channel Tetramerization Domain-Containing Protein 152 3
BTB/POZ Domain-Containing Protein KCTD152

External Ids:    HGNC: 232971   Entrez Gene: 790472   Ensembl: ENSG000001538857   OMIM: 6152405   UniProtKB: Q96SI13   

Export aliases for KCTD15 gene to outside databases

Previous GC identifers: GC19P038979 GC19P030786


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KCTD15 Gene:
KCTD15 (potassium channel tetramerization domain containing 15) is a protein-coding gene. An important paralog of this gene is KCTD1.

UniProtKB/Swiss-Prot: KCD15_HUMAN, Q96SI1
Function: During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2
transcriptional activity by interaction with its activation domain

Gene Wiki entry for KCTD15 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the KCTD15 gene promoter:
         MEF-2A   SRF   TBP   SRF (504 AA)   IRF-7A   aMEF-2   Tal-1beta   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCTD15 promoter sequence
   Search Chromatin IP Primers for KCTD15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KCTD15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.11   Ensembl cytogenetic band:  19q13.11   HGNC cytogenetic band: 19q13.12

KCTD15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD15 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P034287:  view genomic region     (about GC identifiers)

Start:
34,286,838 bp from pter      End:
34,306,668 bp from pter
Size:
19,831 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KCD15_HUMAN, Q96SI1 (See protein sequence)
Recommended Name: BTB/POZ domain-containing protein KCTD15  
Size: 283 amino acids; 31942 Da
Subunit: Interacts with TFAP2A; this interaction inhibits TFAP2A transcriptional activation
Secondary accessions: A8K600 Q9BVI6
Alternative splicing: 2 isoforms:  Q96SI1-1   Q96SI1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KCTD15: NX_Q96SI1

Explore proteomics data for KCTD15 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KCTD15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001123466.1  NP_001123467.1  NP_076981.2  

    ENSEMBL proteins: 
     ENSP00000466357   ENSP00000466804   ENSP00000467955   ENSP00000464722   ENSP00000467612  
     ENSP00000284006   ENSP00000464812   ENSP00000467353   ENSP00000394390   ENSP00000477220  

    KCTD15 Human Recombinant Protein Products:

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    Novus Biologicals KCTD15 Proteins
    Novus Biologicals KCTD15 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for KCTD15
    Cloud-Clone Corp. Proteins for KCTD15

     
    Search eBioscience for Proteins for KCTD15 

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    Cloud-Clone Corp. CLIAs for KCTD15
    Search eBioscience for ELISAs for KCTD15 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR003131 T1-type_BTB

    Graphical View of Domain Structure for InterPro Entry Q96SI1

    ProtoNet protein and cluster: Q96SI1

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: KCD15_HUMAN, Q96SI1
    Similarity: Contains 1 BTB (POZ) domain


    Find genes that share domains with KCTD15           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCD15_HUMAN, Q96SI1
    Function: During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2
    transcriptional activity by interaction with its activation domain

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KCTD15           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for KCTD15:
     Decreased viability 

         1 MGI phenotypic allele for Kctd15 (no phenotypes)

    Find genes that share phenotypes with KCTD15           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KCTD15
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KCTD15
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KCTD15

    miRNA
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    miRTarBase miRNAs that target KCTD15:
    hsa-mir-25-3p (MIRT050356), hsa-mir-423-5p (MIRT038168), hsa-mir-192-5p (MIRT026293), hsa-mir-29c-3p (MIRT020375), hsa-mir-186-5p (MIRT021087), hsa-mir-215-5p (MIRT024933), hsa-mir-342-3p (MIRT043670), hsa-mir-1229-3p (MIRT036284)

    Block miRNA regulation of human, mouse, rat KCTD15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD15 (see all 67):
    hsa-miR-631 hsa-miR-300 hsa-miR-146a hsa-miR-298 hsa-miR-629 hsa-miR-200b hsa-miR-4324 hsa-miR-455-5p
    SwitchGear 3'UTR luciferase reporter plasmidKCTD15 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat KCTD15

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    GenScript: all cDNA clones in your preferred vector (see all 3): KCTD15 (NM_024076)
    Sino Biological Human cDNA Clone for KCTD15
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KCTD15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD15

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD15


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KCTD15 About    
    See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Bitter Taste Signaling0.44
    Melatonin Signaling0.72
    Sperm Motility0.37
    Cellular Effects of Sildenafil0.46
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47
    Cholera Infection0.40
    Aldosterone Signaling in Epithelial Cells0.47
    4Hepatic ABC Transporters
    Hepatic ABC Transporters0.41
    MODY (Maturity-Onset Diabetes of Young)0.41

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for KCTD15 (see all 13)
        Cholera Infection
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Hepatic ABC Transporters
    PKA Signaling
    Sweet Taste Signaling



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KCTD15
    Interactions:

        Search GeneGlobe Interaction Network for KCTD15

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for KCTD15 (Q96SI12, 3 ENSP000003943904) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000215641P143732, 3MINT-65370 I2D: score=4 
    ENSG00000229006P143732, 3MINT-65370 I2D: score=4 
    ENSG00000234495P143732, 3MINT-65370 I2D: score=4 
    ENSG00000237071P143732, 3MINT-65370 I2D: score=4 
    TRIM27P143732, 3MINT-65370 I2D: score=4 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0051260protein homooligomerization IEA--

    Find genes that share ontologies with KCTD15           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KCTD15 (KCD15)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KCTD15 gene (3 alternative transcripts): 
    NM_001129994.1  NM_001129995.1  NM_024076.2  

    Unigene Cluster for KCTD15:

    Potassium channel tetramerisation domain containing 15
    Hs.221873  [show with all ESTs]
    Unigene Representative Sequence: NM_024076
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587658 ENST00000587559 ENST00000588637 ENST00000590771 ENST00000589786
    ENST00000284006(uc002nuv.3 uc002nuy.4 uc010xrt.2 uc002nux.4)
    ENST00000588881 ENST00000590906 ENST00000430256(uc002nuw.4) ENST00000592210
    ENST00000590385 ENST00000592363
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KCTD15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KCTD15 (see all 67):
    hsa-miR-631 hsa-miR-300 hsa-miR-146a hsa-miR-298 hsa-miR-629 hsa-miR-200b hsa-miR-4324 hsa-miR-455-5p
    SwitchGear 3'UTR luciferase reporter plasmidKCTD15 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KCTD15
    Predesigned siRNA for gene silencing in human, mouse, rat KCTD15
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): KCTD15 (NM_024076)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCTD15
    Primer
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    OriGene qPCR primer pairs and template standards for KCTD15
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KCTD15
      QuantiTect SYBR Green Assays in human, mouse, rat KCTD15
      QuantiFast Probe-based Assays in human, mouse, rat KCTD15

    Additional mRNA sequence: 

    AK025590.1 AK027901.1 AK096843.1 AK225793.1 AK291465.1 AK294543.1 BC001185.1 BC009335.2 

    8 DOTS entries:

    DT.453844  DT.92427113  DT.97777800  DT.95264141  DT.121498397  DT.121498402  DT.40121488  DT.121498404 

    Selected AceView cDNA sequences (see all 169):

    BF061821 AI803386 BM834184 AI827822 AI989791 BU175567 AI498644 BG677356 
    AA331978 CA950056 AW959399 AI992053 AW510640 BU158268 AA425927 AI263714 
    N31532 BG571742 BE312560 CA943857 AA461228 AI808997 BM840722 AI355596 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KCTD15 (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c · 9d ^ 10 ^ 11a · 11b
    SP1:                                      -     -     -           -                                                                     
    SP2:                                                              -                                                           -         
    SP3:        -     -     -     -     -     -     -     -           -                                                                     
    SP4:                    -     -     -     -     -     -           -                                                                     
    SP5:                    -     -     -     -     -     -                                                                                 


    ECgene alternative splicing isoforms for KCTD15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KCTD15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAAAGCTTC
    KCTD15 Expression
    About this image

    KCTD15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KCTD15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.221873
        Custom PCR Arrays for KCTD15
    Primer
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    QuantiTect SYBR Green Assays in human, mouse, rat KCTD15
    QuantiFast Probe-based Assays in human, mouse, rat KCTD15
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KCTD15 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kctd151 , 5 potassium channel tetramerisation domain containing more1, 5 88.46(n)1
    97.53(a)1
      7 (20.41 cM)5
    2331071  NM_146188.11  NP_666300.11 
     346390145 
    chicken
    (Gallus gallus)
    Aves KCTD151 potassium channel tetramerisation domain containing more 74.97(n)
    90.94(a)
      415779  XM_414140.4  XP_414140.4 
    lizard
    (Anolis carolinensis)
    Reptilia KCTD156
    potassium channel tetramerization domain containin...
    79(a)
    1 ↔ 1
    GL343508.1(96592-154448)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC761382 hypothetical protein MGC76138 77.25(n)    BC063913.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.155922 Transcribed sequence with moderate similarity to protein more 76.08(n)    BM342205.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104401 CG10440 60.71(n)
    54.89(a)
      37456  NM_001259520.1  NP_001246449.1 


    ENSEMBL Gene Tree for KCTD15 (if available)
    TreeFam Gene Tree for KCTD15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KCTD15 gene
    KCTD12  KCTD82  KCTD162  KCTD42  KCTD112  KCNRG2  KCTD122  KCTD212  
    KCTD62  KCTD142  
    5 SIMAP similar genes for KCTD15 using alignment to 7 protein entries:     KCD15_HUMAN (see all proteins):
    KCTD1    KCTD21    KCTD6    KCTD19    SHKBP1

    Find genes that share paralogs with KCTD15           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KCTD15 (see all 418)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1488316111,2
    --34285813(+) ACGCGC/TAGAGA 3 -- us2k10--------
    rs38103611,2
    C,F,H--34285951(-) AAAGAA/GGCCCT 3 -- us2k121Minor allele frequency- G:0.44NS EA WA NA CSA 2343
    rs1832015201,2
    --34286025(+) TTTGTA/GAGCTA 3 -- us2k10--------
    rs1434408071,2
    --34286249(+) GCGAGA/GTCCTC 3 -- us2k10--------
    rs1159194101,2
    F--34286516(+) GCGCTC/TCGTTT 3 -- us2k11Minor allele frequency- T:0.26WA 118
    rs1878452131,2
    --34286572(+) GCGGGA/GCGCAA 3 -- us2k10--------
    rs2856771,2
    C,F--34286666(-) CCCGGG/ACGCCC 3 -- us2k16Minor allele frequency- A:0.43NA CSA WA EA 363
    rs1929549521,2
    --34286722(+) CGCGCC/TGCGCG 3 -- us2k10--------
    rs1132349811,2
    C,F--34286841(+) GCGGGG/TCAGAG 3 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1849769501,2
    --34286889(+) CCTGGA/CCCCCG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for KCTD15 (34286838 - 34306668 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for KCTD15:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2464CNV Insertion18451855
    nsv833809CNV Loss17160897
    nsv911609CNV Loss21882294
    dgv139e55CNV Gain17911159
    nsv828528CNV Gain20364138
    dgv1073e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KCTD15
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615240    OMIM disorders: --


    Find genes that share disorders with KCTD15           About GenesLikeMe

    Genetic Association Database (GAD): KCTD15
    Human Genome Epidemiology (HuGE) Navigator: KCTD15 (23 documents)

    Export disorders for KCTD15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KCTD15 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with KCTD15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Inhibition of neural crest formation by Kctd15 involves regulation of transcription factor AP-2. (PubMed id 23382213)1, 2 Zarelli V.E. and Dawid I.B. (Proc. Natl. Acad. Sci. U.S.A. 2013)
    2. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)1, 4 Speliotes E.K....Loos R.J. (Nat. Genet. 2010)
    3. Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies. (PubMed id 20724581)1, 4 den Hoed M....Loos R.J. (Diabetes 2010)
    4. Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. (PubMed id 20520848)1, 4 Elks C.E....Ong K.K. (PLoS Med. 2010)
    5. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. (PubMed id 20571754)1, 4 Fontaine-Bisson B....Franks P.W. (Diabetologia 2010)
    6. Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)1, 4 Ng M.C....Ma R.C. (J. Clin. Endocrinol. Metab. 2010)
    7. Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa? (PubMed id 19746409)1, 4 Brandys M.K....Adan R.A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    8. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (J. Allergy Clin. Immunol. 2010)
    9. Obesity and diabetes genetic variants associated with gestational weight gain. (PubMed id 20816152)1, 4 Stuebe A.M....Siega-Riz A.M. (Am. J. Obstet. Gynecol. 2010)
    10. Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus. (PubMed id 19910641)1, 4 He M....Qi L. (Arterioscler. Thromb. Vasc. Biol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79047 HGNC: 23297 AceView: KCTD15 Ensembl:ENSG00000153885 euGenes: HUgn79047
    ECgene: KCTD15 H-InvDB: KCTD15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KCTD15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for KCTD15 gene:
    Search GeneIP for patents involving KCTD15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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