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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

KCTD12 Gene

protein-coding GIFtS: 55
GCID: GC13M077454

potassium channel tetramerisation domain containing 12

(Previous name: chromosome 13 open reading frame 2 )
(Previous symbol: C13orf2)

Explore 5 diseases affiliated with
KCTD12 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Potassium Channel Tetramerisation Domain Containing 12¹ ²		Chromosome 13 Open Reading Frame 2¹
C13orf2¹ ² ³		PFETIN²
PFET1¹ ² ³		BTB/POZ Domain-Containing Protein KCTD12²
KIAA1778¹ ³		Pfetin³
Predominantly Fetal Expressed T1 Domain² ³

External Ids:	HGNC: 14678¹	Entrez Gene: 115207²	Ensembl: ENSG00000178695⁷	OMIM: 610521⁵	UniProtKB: Q96CX2³

Export aliases for KCTD12 gene to outside databases

Previous GC identifers: GC13M075255 GC13M075252 GC13M076352 GC13M058151

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: KCD12_HUMAN, Q96CX2

Function: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response.

Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and

promoting desensitization (By similarity)

Gene Wiki entry for KCTD12

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000013.10 NC_018924.1 NT_024524.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the KCTD12 gene promoter:
AML1a Pbx1a Pax-5 POU6F1 (c2) AP-4 MIF-1 CREB deltaCREB IRF-7A
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KCTD12 promoter sequence

Search SABiosciences Chromatin IP Primers for KCTD12

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCTD12

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q22.3 Ensembl cytogenetic band: 13q22.3 HGNC cytogenetic band: 13q21

KCTD12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCTD12 gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13M077454: view genomic region (about GC identifiers)

Start:	77,454,304 bp from pter	End:	77,460,540 bp from pter
Size:	6,237 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KCD12_HUMAN, Q96CX2 (See protein sequence)

Recommended Name: BTB/POZ domain-containing protein KCTD12

Size: 325 amino acids; 35701 Da

Subunit: Interacts as a tetramer with GABRB1 and GABRB2

Subcellular location: Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell

membrane (By similarity)

Explore the universe of human proteins at neXtProt for KCTD12: NX_Q96CX2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96CX2

KCTD12 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_612453.1

ENSEMBL proteins:

ENSP00000366694 ENSP00000317141

Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for KCTD12

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0030054	cell junction	IEA	--
GO:0042734	presynaptic membrane	IEA	--
GO:0043235	receptor complex	IEA	--
GO:0045211	postsynaptic membrane	IEA	--

KCTD12 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for KCTD12

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

KCTD12 for domains About GeneDecksing

3 InterPro domains/families:

IPR000210 BTB/POZ-like

IPR011333 BTB/POZ_fold

IPR003131 T1-type_BTB

Graphical View of Domain Structure for InterPro Entry Q96CX2

ProtoNet protein and cluster: Q96CX2

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: KCD12_HUMAN, Q96CX2

Function: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response.

Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and

promoting desensitization (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: KCTD12 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KCTD12
		8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate KCTD12 (see all 59):
		hsa-miR-142-5p hsa-miR-323-3p hsa-miR-4307 hsa-miR-607 hsa-miR-300 hsa-miR-200a hsa-miR-139-5p hsa-miR-1260b

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for KCTD12

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		Search LifeMap BioReagents cell lines for KCTD12

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD12

1 GenomeRNAi human phenotype for KCTD12:

Synthetic lethal with Ras

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Sweet Taste Signaling

Sweet Taste Signaling	1.00	Bitter Taste Signaling	0.44
Melatonin Signaling	0.72	Sperm Motility	0.36
Cellular Effects of Sildenafil	0.46

Activation of cAMP-Dependent PKA

	Activation of cAMP-Dependent PKA	1.00			PKA Signaling	0.56
	cAMP Pathway	0.77

Neuropathic Pain-Signaling in Dorsal Horn Neurons

	Neuropathic Pain-Signaling in Dorsal Horn Neurons	1.00			Cholera Infection	0.40
	Aldosterone Signaling in Epithelial Cells	0.47

Hepatic ABC Transporters

Hepatic ABC Transporters

1.00

MODY (Maturity-Onset Diabetes of Young)

0.41

5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KCTD12 (see all 13)

	Cholera Infection
	Neuropathic Pain-Signaling in Dorsal Horn Neurons
	Hepatic ABC Transporters
	PKA Signaling
	Sweet Taste Signaling

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for KCTD12

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/21 Interacting proteins for KCTD12 (Q96CX2^{2, 3} ENSP00000317141⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 21)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TNFRSF1B	P20333²^,³	MINT-49423 I2D: score=2
RASSF5	Q8WWW0³, ENSP00000347443⁴	I2D: score=3 STRING: ENSP00000347443
RIPK2	O43353³, ENSP00000220751⁴	I2D: score=2 STRING: ENSP00000220751
ARAP1	Q96P48³, ENSP00000377233⁴	I2D: score=1 STRING: ENSP00000377233
ATG5	Q9H1Y0³, ENSP00000343313⁴	I2D: score=1 STRING: ENSP00000343313

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	IEA	--
GO:0051260	protein homooligomerization	IEA	--

KCTD12 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KCTD12
Search CenterWatch for drugs/clinical trials and news about KCTD12 / KCD12

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for KCTD12 gene:

NM_138444.3

Unigene Cluster for KCTD12:

Potassium channel tetramerisation domain containing 12

Hs.644125 [show with all ESTs]

Unigene Representative Sequence: NM_138444

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000377474(uc010aeu.1) ENST00000317765(uc001vka.1)

miRNA Products:		OriGene 3'-UTR Clone: KCTD12 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KCTD12
		8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate KCTD12 (see all 59):
		hsa-miR-142-5p hsa-miR-323-3p hsa-miR-4307 hsa-miR-607 hsa-miR-300 hsa-miR-200a hsa-miR-139-5p hsa-miR-1260b

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCTD12

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCTD12

Additional cDNA sequence:

AB593182.1 AF052169.1 AF359381.1 AK057635.1 AK128363.1 AK311268.1 AK311543.1 BC013764.1

14 DOTS entries:

DT.99945554 DT.75148475 DT.100649928 DT.95145895 DT.120780028 DT.120780030 DT.120780038 DT.452943

DT.120780020 DT.120780027 DT.120780042 DT.120780052 DT.91765696 DT.95145896

24/129 AceView cDNA sequences (see all 129):

N47068 AI188744 BU074517 AA007212 AA973828 AI246472 AI350690 BM723864

BG230560 AK057635 AA007211 AA908162 BF589903 BU735630 BM995949 BE502121

BU625371 BM677106 BM697859 BU737138 AA477748 AA404400 BX093379 BC013764

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

KCTD12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCAAACTTT

About this image

KCTD12 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 9 LifeMap Cells

Name

Category

PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)

Blood, Endothelium

PureStem™ endothelial Progenitor 30-SM2-3 (Embryonic Progenitor Cell)

Blood, Endothelium

PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)

Endothelium

PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)

Endothelium

PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)

Endothelium

PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

PureStem™ progenitor U31 (Embryonic Progenitor Cell)

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See KCTD12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KCTD12

SOURCE GeneReport for Unigene cluster: Hs.644125

UniProtKB/Swiss-Prot: KCD12_HUMAN, Q96CX2

Tissue specificity: Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and,

in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung

SABiosciences Custom PCR Arrays for KCTD12

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCTD12

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCTD12

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for KCTD12 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	KCTD12⁶	--	66(a)	1 ↔ 1	3(86712468-86713442)
African clawed frog (Xenopus laevis)	Amphibia	CF270687.1²	--	77.27(n)		CF270687.1
zebrafish (Danio rerio)	Actinopterygii	AY120891.1²	--	76.66(n)		373865 AY120891.1
fruit fly (Drosophila melanogaster)	Insecta	CG10830¹	CG10830	62.39(n) 50(a)		42475 NM_142669.4 NP_650926.1
worm (Caenorhabditis elegans)	Secernentea	VM106R.1¹	hypothetical protein	50.56(n) 45.42(a)		4926896 NM_001083165.1 NP_001076634.1

ENSEMBL Gene Tree for KCTD12 (if available)
TreeFam Gene Tree for KCTD12 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for KCTD12 gene

KCTD1² KCTD15² KCTD8² KCTD16² KCTD4² KCNRG² KCTD11² KCTD21²

KCTD6² KCTD14²

2 SIMAP similar genes for KCTD12 using alignment to 1 protein entry: KCD12_HUMAN:

KCTD16 KCTD8

KCTD12 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs142226189^1,2		--	77453820(+)	`CCAGAC/TGACTT`	1	--	int¹		0	--	--	--	--
rs189932385^1,2		--	77453996(+)	`ATCTCA/GAAGCT`	1	--	int¹		0	--	--	--	--
rs182548257^1,2		--	77454164(+)	`TGGCCA/GGTTCC`	1	--	int¹		0	--	--	--	--
rs35527145^1,2	C,	--	77454382(+)	`TCATTA/CCTTCA`	1	--	ut3¹		2		NA	122
rs6835^1,2	C,F,H,	--	77454481(-)	`GAATTT/CCTTCA`	1	--	ut3¹		26		MN NS EA NA WA CSA	2952
rs144865290^1,2		--	77454515(+)	`AGACTC/TTGACT`	1	--	ut3¹		0	--	--	--	--
rs148084749^1,2		--	77454547(+)	`GGATTA/TTTTTC`	1	--	ut3¹		0	--	--	--	--
rs9320^1,2	F,	--	77454549(+)	`ATTTTT/CTTCTT`	1	--	ut3¹ trp³		2		MN WA	302
rs116539990^1,2	C,F,	--	77454789(+)	`CTTTGT/CCACTA`	1	--	ut3¹		1		WA	118
rs200829866^1,2		--	77454794(+)	`TCACT-/AAATGGT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for KCTD12 (77454304 - 77460540 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KCTD12
1 CNV: 66486

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCTD12

DNA2.0 Custom Variant and Variant Library Synthesis for KCTD12

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KCTD12 for disorders           About GeneDecksing

OMIM gene information: 610521    OMIM disorders: --

5 diseases for KCTD12:    About MalaCards

gastrointestinal stromal tumor bipolar i disorder clear cell sarcoma coronary heart disease

sarcoma

1 disease from the University of Copenhagen DISEASES database for KCTD12:

Gastrointestinal stromal tumor

Human Genome Epidemiology (HuGE) Navigator: KCTD12 (3 documents)

Export disorders for KCTD12 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for KCTD12 gene, integrated from 9 sources (see all 29):
(articles sorted by number of sources associating them with KCTD12)

Utopia: connect your pdf to the dynamic
world of online information

Isolation from cochlea of a novel human intronless gene with predominant fetal expression. (PubMed id 15357420)^{1, 2, 3, 9} Resendes B.L.... Morton C.C. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Pfetin as a prognostic biomarker of gastrointestinal stromal tumors revealed by proteomics. (PubMed id 18347171)^{1, 9} Suehara Y....Hirohashi S. (2008)
Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)¹ Oshikawa K....Nakayama K.I. (2012)
A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking. (PubMed id 21275903)¹ Yoon H.Y....Randazzo P.A. (2011)
Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)¹ Emanuele M.J....Elledge S.J. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 115207	HGNC: 14678	AceView: KCTD12	Ensembl:ENSG00000178695	euGenes: HUgn115207
ECgene: KCTD12	H-InvDB: KCTD12

(According to HUGE)
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HUGE: KIAA1778

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for KCTD12	Pharmacogenomics, SNPs, Pathways

Intellectual Property for KCTD12 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for KCTD12 gene:
Search GeneIP for patents involving KCTD12

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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KCTD12 Gene

potassium channel tetramerisation domain containing 12

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KCTD12 Gene

potassium channel tetramerisation domain containing 12

Aliasesfor KCTD12 gene

Summariesfor KCTD12 gene

Genomic Viewsfor KCTD12 gene

Proteinsfor KCTD12 gene

Protein Domains /Familiesfor KCTD12 gene

Functionfor KCTD12 gene

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for KCTD12 gene

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for KCTD12 gene

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for KCTD12 gene

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Expression
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Orthologs
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Intellectual Property
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