KCNU1 Gene
protein-coding GIFtS: 46
GCID: GC08P036641
|
|
potassium channel, subfamily U, member 1
| |
Aliases
for KCNU1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Potassium Channel, Subfamily U, Member 11 2 | | Calcium-Activated Potassium Channel Subunit Alpha-32 3 | | KCNMC11 2 3 | | Calcium-Activated Potassium Channel, Subfamily M Subunit Alpha-32 3 | | KCa5.11 2 | | Slowpoke Homolog 32 3 | | Kcnma31 2 | | Potassium Channel Subfamily U Member 12 | | Slo31 2 | | KCNMA33 | | KCa52 3 | | SLO33 |
Export aliases for KCNU1 gene to outside databasesPrevious GC identifers: GC08U990155 GC08P036761 GC08P035176 |
Summaries
for KCNU1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: KCNU1_HUMAN, A8MYU2Function: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediatesexport of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilizationwhere changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it isnot activated by Ca(2+) or Mg(2+) (By similarity)
 summary
for KCNU1: Ca2+-activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+
ions across biological membranes. They are broadly classified into three subtypes, SK, IK and BK channels,
based on their conductance (small, intermediate and big conductance respectively). The small conductance KCa
channels (KCa2.1, 2.2 and 2.3, also known as SK1, SK2 and SK3 respectively) and the intermediate conductance
KCa channel (KCa3.1, also known as SK4) are voltage-insensitive and are activated by Ca2+-calmodulin. Both
play important roles in many processes involving Ca2+-dependent signalling in both electrically excitable
and non-excitable cells. The BK family of KCa channels (also known as Slo or Maxi-K channels) are also
voltage-sensitive and include KCa1.1 (Slo1), KCa4.1 (Slo2.2), KCa4.2 (Slo2.1) and KCa5.1 (Slo3). These
channels do not require calmodulin for activation as they contain three direct bivalent cation binding
sites.
Gene Wiki entry for KCNU1
|
Genomic Views
for KCNU1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KCNU1 gene promoter:
RFX1 ISGF-3 Nkx2-5 POU3F2 Gfi-1 Evi-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KCNU1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNU1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p11.23 Ensembl cytogenetic band: 8p11.23 HGNC cytogenetic band: 8p11.2KCNU1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P036641: view genomic region
(about GC identifiers)
Start:
|
36,641,842 bp from pter |
End:
|
36,793,646 bp from pter |
Size:
|
151,805 bases |
Orientation:
|
plus strand |
|
Proteins
for KCNU1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KCNU1_HUMAN, A8MYU2 (See
protein sequence)Recommended Name: Potassium channel subfamily U member 1 Size: 1149 amino acids; 129543 Da
Subunit: Homotetramer; which constitutes the calcium-activated potassium channel (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
1 PDB 3D structure from  and Proteopedia  for KCNU1:4HPF (3D)
Explore the universe of human proteins at neXtProt for KCNU1: NX_A8MYU2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A8MYU2
KCNU1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001027006.2
ENSEMBL proteins: ENSP00000429951 ENSP00000382770 ENSP00000428552 ENSP00000429149 ENSP00000428106
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008076 | voltage-gated potassium channel complex |
IBA | -- | | GO:0016021 | integral to membrane |
-- | -- |
KCNU1 for ontologies About GeneDecksing
KCNU1 Antibody Products:
Assay Products for KCNU1: |
Protein
Domains /
Families
for KCNU1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KCNU1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A8MYU2ProtoNet protein and cluster: A8MYU2 UniProtKB/Swiss-Prot: KCNU1_HUMAN, A8MYU2Domain: The S4 segment, which is characterized by a series of positively charged amino acids at every third position,is part of the voltage-sensor (By similarity)Domain: The pore-forming domain (also referred as P region) is imbedded into the membrane, and forms the selectivityfilter of the pore. It contains the signature sequence of potassium channels that displays selectivity to potassium(By similarity)Domain: The RCK N-terminal domain mediates the homotetramerization, thereby promoting the assembly of monomers intofunctional potassium channel (By similarity)Domain: The C-terminal cytosolic region confers the pH-dependence (By similarity)Similarity: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa5.1/KCNU1sub-subfamilySimilarity: Contains 1 RCK N-terminal domain |
Function
for KCNU1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KCNU1_HUMAN, A8MYU2Function: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediatesexport of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilizationwhere changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it isnot activated by Ca(2+) or Mg(2+) (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNU1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNU1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KCNU1 (NM_001031836) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNU1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KCNU1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNU1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0005216 | ion channel activity |
-- | -- | | GO:0005249 | voltage-gated potassium channel activity |
IBA | -- | | GO:0015269 | calcium-activated potassium channel activity |
-- | -- | | GO:0060072 | large conductance calcium-activated potassium channel activity |
IBA | -- |
KCNU1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for KCNU1:
Animal Models:
Mouse knock-outs for KCNU1: Kcnu1tm1Cmsa Kcnu1tm1.2Clin
1 MGI mutant phenotype (inferred from 3 alleles ) (MGI details for Kcnu1):
KCNU1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KCNU1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sweet Taste Signaling | | | 2 | Activation of cAMP-Dependent PKA | | | 3 | Neuropathic Pain-Signaling in Dorsal Horn Neurons | | | 4 | Hepatic ABC Transporters | | | 5 | GnRH signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KCNU1 (see all 13)
1 
Kegg Pathway (Kegg details for KCNU1):
KCNU1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCNU1
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5 Interacting proteins for KCNU1 (ENSP000003827704) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0071805 | potassium ion transmembrane transport |
IBA | -- |
KCNU1 for ontologies About GeneDecksing
|
Drugs & Compounds
for KCNU1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for KCNU1 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| YS-035 hydrochloride | Inhibits K+ outward/pacemaker current | [33978-72-2] | | DMP 543 | K+ channel blocker and potent ACh release enhancer | [160588-45-4] | | | -- | | 4-Aminopyridine | Non-selective KV channel blocker | [504-24-5] |
1 HMDB Compound for KCNU1 About this table
Search CenterWatch for drugs/clinical trials and news about KCNU1
|
Transcripts
for KCNU1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KCNU1 gene: NM_001031836.2 Unigene Cluster for KCNU1: Potassium channel, subfamily U, member 1 Hs.13861 [show with all ESTs]Unigene Representative Sequence: BC0287015 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523973 ENST00000399881(uc010lvw.3) ENST00000522372(uc003xjw.2)
ENST00000522417 ENST00000518904
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNU1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNU1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KCNU1 (NM_001031836) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNU1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KCNU1 |
Additional cDNA sequence: AK302391.1 BC028701.2 3 DOTS entries: DT.91917608 DT.120648295 DT.209915
GeneLoc Exon Structure
|
Expression
for KCNU1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KCNU1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCATTTTTCT
About this image
See KCNU1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KCNU1
SOURCE GeneReport for Unigene cluster: Hs.13861
UniProtKB/Swiss-Prot: KCNU1_HUMAN, A8MYU2Tissue specificity: Testis-specific
SABiosciences Custom PCR Arrays for KCNU1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNU1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KCNU1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNU1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNU1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNU1 |
Orthologs
for KCNU1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KCNU1 gene from 3/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KCNU16 |
Uncharacterized protein |
44(a) |
1 ↔ 1 |
22(1979617-2055205) |
lizard
(Anolis carolinensis) |
Reptilia |
KCNU16 |
-- |
47(a) |
1 ↔ 1 |
GL343624.1(275649-363051) |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
39(a) |
1 ↔ 1 |
GroupUn.63(36310-79631) |
ENSEMBL Gene Tree for KCNU1 (if available)
TreeFam Gene Tree for KCNU1 (if available) |
Paralogs
for KCNU1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KCNU1 gene
- KCNMA12 KCNT12 KCNT22
1 SIMAP similar gene for KCNU1 using alignment to 5 protein entries: KCNU1_HUMAN (see all proteins):KCNMA1
KCNU1 for paralogs About GeneDecksing
|
Genomic Variants
for KCNU1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KCNU1 (36641842 - 36793646 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KCNU1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNU1 |
|
Disorders
/ Diseases
for KCNU1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KCNU1 for disorders About GeneDecksing
7  diseases for KCNU1: About MalaCardsmale infertility infertility maturity-onset diabetes of the young aldosteronism
cholera hepatitis neuronitis
1 disease from the University of Copenhagen DISEASES database for KCNU1:Male infertility Human Genome Epidemiology (HuGE) Navigator: KCNU1 (1 document)
Export disorders for KCNU1 gene to outside databases
|
Publications
for KCNU1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KCNU1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KCNU1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)1, 2 Nusbaum C....Lander E.S. (2006)
- International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. (PubMed id 16382103)1, 3 Wei A.D....Wulff H. (2005)
- Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes. (PubMed id 9452476)1, 2 Schreiber M.... Salkoff L. (1998)
- Functional and structural analysis of the human SLO3 p H- and voltage-gated K+ channel. (PubMed id 23129643)1 Leonetti M.D....Mackinnon R. (2012)
- Genetic variants associated with breast size also infl uence breast cancer risk. (PubMed id 22747683)1 Eriksson N....Tung J.Y. (2012)
- Genome-wide detection of allele specific copy number v ariation associated with insulin resistance in African Americans from the HyperG EN study. (PubMed id 21901158)1 Irvin M.R....Arnett D.K. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for KCNU1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KCNU1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KCNU1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KCNU1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KCNU1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KCNU1 gene:
Search GeneIP for patents involving KCNU1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KCNU1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KCNU1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCNU1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNU1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KCNU1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNU1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNU1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KCNU1 | | OriGene Custom Protein Services for KCNU1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KCNU1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNU1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNU1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNU1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNU1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNU1 |
| |
 |  |  |  | |
| | | | Tocris compounds for KCNU1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | KCNU1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNU1 |
|  |  |  | | | | Search ThermoFisher Antibodies for KCNU1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KCNU1 |
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