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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KCNT2 Gene

protein-coding   GIFtS: 50
GCID: GC01M196194

potassium channel, subfamily T, member 2
 Explore 5 diseases affiliated with
KCNT2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KCNT2    

Aliases
for KCNT2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Potassium Channel, Subfamily T, Member 21 2     Potassium Channel Subfamily T Member 22
SLICK1 2 3 5     Sodium Activated Potassium Channel2
KCa4.21 2     Sodium And Chloride Activated ATP Sensitive Potassium Channel2
SLO2.11 2     Sodium- And Chloride-Activated ATP-Sensitive Potassium Channel2
Sequence Like An Intermediate Conductance Potassium Channel Subunit2 3     Sodium-And Chloride-Activated ATP-Sensitive Potassium Channel (SLICK)2
Sodium And Chloride-Activated ATP-Sensitive Potassium Channel Slo2.12 3     

External Ids:    HGNC: 188661   Entrez Gene: 3434502   Ensembl: ENSG000001626877   OMIM: 6100445   UniProtKB: Q6UVM33   

Export aliases for KCNT2 gene to outside databases

Previous GC identifers: GC01M193941 GC01U900041 GC01M192927 GC01M194461 GC01M167436


Summaries
for KCNT2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: KCNT2_HUMAN, Q6UVM3
Function: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated
by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics,
such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1

summary for KCNT2:
Ca2+-activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+
ions across biological membranes. They are broadly classified into three subtypes, SK, IK and BK channels,
based on their conductance (small, intermediate and big conductance respectively). The small conductance KCa
channels (KCa2.1, 2.2 and 2.3, also known as SK1, SK2 and SK3 respectively) and the intermediate conductance
KCa channel (KCa3.1, also known as SK4) are voltage-insensitive and are activated by Ca2+-calmodulin. Both
play important roles in many processes involving Ca2+-dependent signalling in both electrically excitable
and non-excitable cells. The BK family of KCa channels (also known as Slo or Maxi-K channels) are also
voltage-sensitive and include KCa1.1 (Slo1), KCa4.1 (Slo2.2), KCa4.2 (Slo2.1) and KCa5.1 (Slo3). These
channels do not require calmodulin for activation as they contain three direct bivalent cation binding
sites.

Gene Wiki entry for KCNT2


Genomic Views
for KCNT2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KCNT2 gene promoter:
         TBP   HOXA9   HOXA9B   Pbx1a   Tal-1beta   E47   c-Ets-1   TFIID   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KCNT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for KCNT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q31.3   Ensembl cytogenetic band:  1q31.3   HGNC cytogenetic band: 1q31.3

KCNT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCNT2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M196194:  view genomic region     (about GC identifiers)

Start:
 196,194,909 bp from pter      End:
 196,577,541 bp from pter
Size:
 382,633 bases      Orientation:
 minus strand

Proteins
for KCNT2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KCNT2_HUMAN, Q6UVM3 (See protein sequence)
Recommended Name: Potassium channel subfamily T member 2  
Size: 1135 amino acids; 130501 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: Q3SY59 Q5VTN1 Q6ZMT3
Alternative splicing: 4 isoforms:  Q6UVM3-1   Q6UVM3-2   Q6UVM3-3   Q6UVM3-4   

Explore the universe of human proteins at neXtProt for KCNT2: NX_Q6UVM3

Post-translational modifications:

  • Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain inhibits channel activity1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6UVM3

    • KCNT2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_940905.2  
    ENSEMBL proteins: 
     ENSP00000356403   ENSP00000294725   ENSP00000356401   ENSP00000405474  

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    Uscn Proteins for KCNT2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008076voltage-gated potassium channel complex IBA--
    GO:0016020membrane ----


    KCNT2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for KCNT2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KCNT2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR016040 NAD(P)-bd_dom
     IPR013099 Ion_trans_2
     IPR003929 K_chnl_Ca-activ_BK_asu

    Graphical View of Domain Structure for InterPro Entry Q6UVM3

    ProtoNet protein and cluster: Q6UVM3

    1 Blocks protein family: IPB013099 Ion transport 2

    UniProtKB/Swiss-Prot: KCNT2_HUMAN, Q6UVM3
    Similarity: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.2/KCNT2
    sub-subfamily
    Similarity: Contains 1 RCK N-terminal domain


    Function
    for KCNT2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KCNT2_HUMAN, Q6UVM3
    Function: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated
    by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics,
    such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1

    miRNA
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    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate KCNT2 (see all 31):
    hsa-miR-582-3p hsa-miR-3910 hsa-miR-3607-5p hsa-miR-4307 hsa-miR-607 hsa-miR-522 hsa-miR-4305 hsa-miR-944
    SwitchGear 3'UTR luciferase reporter plasmid: KCNT2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005249voltage-gated potassium channel activity IBA--
    GO:0005524ATP binding IEA--
    GO:0015269calcium-activated potassium channel activity IBA--


    KCNT2 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for KCNT2:
     Increased circadian period len  Synthetic lethal with Ras 


    Pathways & Interactions
    for KCNT2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCNT2

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0071805potassium ion transmembrane transport IBA--


    KCNT2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for KCNT2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for KCNT2 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    YS-035 hydrochlorideInhibits K+ outward/pacemaker current[33978-72-2]
    DMP 543K+ channel blocker and potent ACh release enhancer[160588-45-4]
    --
    4-AminopyridineNon-selective KV channel blocker[504-24-5]

    3 HMDB Compounds for KCNT2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    ChlorineCl2 (see all 13)16887-00-6--
    SodiumSodium (see all 2)7440-23-5--
    Search CenterWatch for drugs/clinical trials and news about KCNT2 

    Transcripts
    for KCNT2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KCNT2 gene: 
    NM_198503.2  

    Unigene Cluster for KCNT2:

    Potassium channel, subfamily T, member 2
    Hs.657046  [show with all ESTs]
    Unigene Representative Sequence: BX647852
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367433(uc001gtd.1 uc001gtf.1 uc001gtg.1) ENST00000498426(uc009wyt.1)
    ENST00000294725(uc001gth.1 uc009wyu.3 uc009wyv.1) ENST00000466914
    ENST00000367431(uc001gte.1) ENST00000451324

    miRNA
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    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate KCNT2 (see all 31):
    hsa-miR-582-3p hsa-miR-3910 hsa-miR-3607-5p hsa-miR-4307 hsa-miR-607 hsa-miR-522 hsa-miR-4305 hsa-miR-944
    SwitchGear 3'UTR luciferase reporter plasmid: KCNT2 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: KCNT2
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNT2
    Clone
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    Primer
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    Additional cDNA sequence: 

    AK021684.1 AK127807.1 AK131498.1 AK309729.1 AY359444.1 BC103947.1 BC103948.1 BC103949.1 
    BC103950.1 BX647852.1 EU251076.1 

    8 DOTS entries:

    DT.100721194  DT.405671  DT.100654802  DT.95309125  DT.405670  DT.91959352  DT.40233416  DT.91652261 

    24/27 AceView cDNA sequences (see all 27):

    AK131498 AK127807 NM_198503 CD643951 BX482174 BU101736 BE350607 AY359444 
    BX503508 AI732637 BX647852 AK021684 AA599741 AU118688 CD656098 AW167113 
    AU145191 Z78375 R51506 R51505 AI791929 AV748447 BG461868 Z78376 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for KCNT2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^
    SP1:                                                                                                                    -                                       
    SP2:                                                                                                              -                                             

    ExUns: 27 ^ 28a · 28b
    SP1:                  
    SP2:                  


    ECgene alternative splicing isoforms for KCNT2

    Expression
    for KCNT2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KCNT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    KCNT2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 5 LifeMap Cells 
    NameCategory
    PureStem™ progenitor T42 (Embryonic Progenitor Cell)
    PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)Lateral Plate Mesoderm, Neural Crest
    PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor E69 (Embryonic Progenitor Cell)
    PureStem™ progenitor T36 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See KCNT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KCNT2

    SOURCE GeneReport for Unigene cluster: Hs.657046
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    In Situ
    Assay Products:     
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    Orthologs
    for KCNT2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for KCNT2 gene from 5/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves KCNT21 potassium channel, subfamily T, member 2 83.67(n)
    91.89(a)    		   429058  XM_426614.3  XP_426614.3 
    lizard
    (Anolis carolinensis)    		 Reptilia KCNT26
    		 --
    		 88(a)
    		 1 ↔ 1
    		 GL343440.1(440801-592457)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC5656911 potassium channel subfamily T member 2-like 68.43(n)
    78.02(a)    		   565691  XM_688958.5  XP_694050.5 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG427326
    		 --
    		 32(a)
    		 1 → many
    		 2R(6209700-6304501)
    worm
    (Caenorhabditis elegans)    		 Secernentea slo-26
    		 SLOwpoke potassium channel family member (slo-2)
    		 42(a)
    		 1 → many
    		 X(11394541-11401483)


    ENSEMBL Gene Tree for KCNT2 (if available)
    TreeFam Gene Tree for KCNT2 (if available) 

    Paralogs
    for KCNT2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KCNT2 gene
    KCNMA12  KCNT12  KCNU12  
    1 SIMAP similar gene for KCNT2 using alignment to 4 protein entries:     KCNT2_HUMAN (see all proteins):
    KCNT1

    KCNT2 for paralogs           About GeneDecksing



    Genomic Variants
    for KCNT2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/131 NCBI SNPs in KCNT2 are shown (see all 131)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1113427961,2
    		--167793144(+) TATTTT/ACTTAT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs168401891,2
    		C,F,H,--167793176(+) TACAAC/TGCCAA 1 -- int119Minor allele frequency- T:0.02NA NS EA WA 2056
    rs741343721,2
    		C,--167793877(+) TCAGCT/CTGTCC 1 -- int12Minor allele frequency- C:0.25WA 120
    rs776149331,2
    		F,--167793983(+) TTATAC/TAGGAT 1 -- int13Minor allele frequency- T:0.06WA NA EA 358
    rs788298861,2
    		F,--167793985(+) ATACAG/TGATTA 1 -- int13Minor allele frequency- T:0.06WA NA EA 358
    rs783362031,2
    		F,--167794266(+) GAAGCG/ATAATA 1 -- int11Minor allele frequency- A:0.08WA 118
    rs286209951,2
    		C,F,--167794336(+) CTGTAG/ATGAAC 1 -- int16Minor allele frequency- A:0.29WA CSA NA 245
    rs789189411,2
    		F,--167794760(+) CATAGA/GAATCA 1 -- int11Minor allele frequency- G:0.02WA 118
    rs176547241,2
    		C,--167794830(+) CTGGCA/GTGAAA 1 -- int14Minor allele frequency- G:0.01NA 262
    rs780256821,2
    		F,--167794902(+) CAAGAT/CAGAAG 1 -- int11Minor allele frequency- C:0.08WA 118

    HapMap Linkage Disequilibrium report for KCNT2 (196194909 - 196444909 bp, first 250kb of KCNT2)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for KCNT2
         1 CNV: 2053

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    Disorders / Diseases
    for KCNT2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KCNT2 for disorders           About GeneDecksing

    OMIM gene information: 610044    OMIM disorders: --

    5 diseases for KCNT2:    About MalaCards
    generalized epilepsy and paroxysmal dyskinesia    generalized epilepsy    pharyngitis    alzheimer's disease
    neuronitis


    Export disorders for KCNT2 gene to outside databases

    Publications
    for KCNT2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KCNT2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KCNT2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP. (PubMed id 14684870)1, 2, 9 Bhattacharjee A....Kaczmarek L.K. (2003)
    2. Opposite regulation of Slick and Slack K+ channels by neuromodulators. (PubMed id 16687497)1, 2, 9 Santi C.M.... Salkoff L. (2006)
    3. International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. (PubMed id 16382103)1, 3 Wei A.D....Wulff H. (2005)
    4. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PubMed id 21116278)1 Furney S.J....Lovestone S. (2010)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    6. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for KCNT2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing KCNT2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 343450 HGNC: 18866 AceView: SLICK Ensembl:ENSG00000162687 euGenes: HUgn343450
    ECgene: KCNT2 H-InvDB: KCNT2

    Other Databases showing KCNT2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KCNT2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KCNT2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for KCNT2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KCNT2 gene:
    Search GeneIP for patents involving KCNT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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