Aliases for KCNMB2 Gene
Aliases for KCNMB2 Gene
- Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2 2 3 5
- Potassium Large Conductance Calcium-Activated Channel, Subfamily M, Beta Member 2 2 3
- Potassium Channel Subfamily M Regulatory Beta Subunit 2 2 3
- Charybdotoxin Receptor Subunit Beta-2 3 4
- Big Potassium Channel Beta Subunit 2 2 3
- MaxiK Channel Beta-Subunit 2 2 3
- BK Channel Beta Subunit 2 2 3
- BK Channel Subunit Beta-2 3 4
- K(VCA)Beta-2 3 4
- Slo-Beta-2 3 4
- Hbeta2 3 4
- Large Conductance Calcium-Activated Potassium Channel Beta 2 Subunit 3
- Calcium-Activated Potassium Channel, Subfamily M Subunit Beta-2 4
- Large-Conductance Ca2+-Activated K+ Channel Beta2 Subunit 3
- Calcium-Activated Potassium Channel Subunit Beta-2 3
- Maxi K Channel Subunit Beta-2 4
- MaxiK Channel Beta 2 Subunit 3
- HCG1646471 3
- BKbeta2 4
- Hbeta3 4
External Ids for KCNMB2 Gene
- HGNC: 6286
- Entrez Gene: 10242
- Ensembl: ENSG00000197584
- OMIM: 605214
- UniProtKB: Q9Y691
Previous GeneCards Identifiers for KCNMB2 Gene
- GC03M181111
- GC03U900023
- GC03P179656
- GC03P179575
- GC03P179736
- GC03P177990
- GC03P175660
- GC03P178420
Summaries for KCNMB2 Gene
-
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]
GeneCards Summary for KCNMB2 Gene
KCNMB2 (Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2) is a Protein Coding gene. Among its related pathways are Vascular smooth muscle contraction and Insulin secretion. GO annotations related to this gene include potassium channel regulator activity and ion channel inhibitor activity. An important paralog of this gene is ENSG00000275163.
UniProtKB/Swiss-Prot for KCNMB2 Gene
-
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
-
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCNMB2 Gene
Genomics for KCNMB2 Gene
Regulatory Elements for KCNMB2 Gene
Enhancers for KCNMB2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH03G178237 | 0.5 | ENCODE | 11.4 | -35.0 | -34977 | 1.0 | GATA3 HDAC2 POU5F1 CHD7 | KCNMB2 GC03P178121 |
| GH03G178525 | 0.5 | ENCODE | 5.6 | +254.4 | 254435 | 3.2 | PKNOX1 SMARCA4 PBX2 ZIC2 | KCNMB2 ENSG00000271131 KCNMB2-AS1 |
| GH03G178392 | 0.6 | Ensembl ENCODE | 4.6 | +120.2 | 120224 | 1.3 | JUNB | KCNMB2 LOC105374235 ENSG00000275163 |
| GH03G178551 | 0.6 | Ensembl | 4.1 | +279.2 | 279169 | 0.6 | ZFHX2 EED PBX2 CEBPB CEBPG MYC | KCNMB2 ENSG00000271131 KCNMB2-AS1 |
| GH03G178403 | 0.5 | ENCODE | 4.7 | +132.4 | 132445 | 2.9 | PBX2 CUX1 FOXP2 EP300 | LINC01014 KCNMB2 ENSG00000275163 LOC105374235 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around KCNMB2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the KCNMB2 gene promoter:
Regulatory Element Products
Genomic Location for KCNMB2 Gene
- Chromosome:
- 3
- Start:
- 178,272,932 bp from pter
- End:
- 178,844,429 bp from pter
- Size:
- 571,498 bases
- Orientation:
- Plus strand
Genomic View for KCNMB2 Gene
Genes around KCNMB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q26.32 by Ensembl
- 3q26.32 by Entrez Gene
- 3q26.32 by HGNC
KCNMB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KCNMB2 Gene
Proteins for KCNMB2 Gene
-
Protein details for KCNMB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y691-KCMB2_HUMAN
- Recommended name:
- Calcium-activated potassium channel subunit beta-2
- Protein Accession:
- Q9Y691
Protein attributes for KCNMB2 Gene
- Size:
- 235 amino acids
- Molecular mass:
- 27130 Da
- Quaternary structure:
-
- Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB2 per KCNMA1 tetramer.
Post-translational modifications for KCNMB2 Gene
- N-glycosylated.
- Glycosylation at posLast=8888, posLast=9696, and isoforms=119
- Modification sites at PhosphoSitePlus
Other Protein References for KCNMB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for KCNMB2
- Novus Biologicals Antibodies for KCNMB2
-
Abcam antibodies for KCNMB2
- Invitrogen Antibodies for KCNMB2
- antibodies-online Antibodies for KCNMB2: See all 80
- GeneTex KCNMB2 antibody for KCNMB2
Protein Products
-
OriGene Purified Proteins for KCNMB2
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- Search GeneTex for Proteins for KCNMB2
-
Abcam proteins for KCNMB2
Assay Products
No data available for DME Specific Peptides for KCNMB2 Gene
Domains & Families for KCNMB2 Gene
Gene Families for KCNMB2 Gene
Protein Domains for KCNMB2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for KCNMB2 Gene
- GenScript: Design optimal peptide antigens:
-
- Large-conductance Ca2+-activated K+ channel beta2 subunit (B5BNW6_HUMAN)
- Large-conductance Ca2+-activated K+ channel beta2 subunit (B5BNW7_HUMAN)
- Large-conductance Ca2+-activated K+ channel beta2 subunit (B5BNW8_HUMAN)
- Large-conductance Ca2+-activated K+ channel beta2 subunit (B5BNW9_HUMAN)
- Large-conductance Ca2+-activated K+ channel beta2 subunit (B5BNX0_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y691UniProtKB/Swiss-Prot:
KCMB2_HUMAN :- The ball and chain domain mediates the inactivation of KCNMA1. It occludes the conduction pathway of KCNMA1 channels, and comprises the pore-blocking ball domain (residues 1-17) and the chain domain (residues 20-45) linking it to the transmembrane segment. The ball domain is made up of a flexible N-terminus anchored at a well ordered loop-helix motif. The chain domain consists of a 4-turn helix with an unfolded linker at its C-terminus.
- Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB2 subfamily.
- Domain:
-
- The ball and chain domain mediates the inactivation of KCNMA1. It occludes the conduction pathway of KCNMA1 channels, and comprises the pore-blocking ball domain (residues 1-17) and the chain domain (residues 20-45) linking it to the transmembrane segment. The ball domain is made up of a flexible N-terminus anchored at a well ordered loop-helix motif. The chain domain consists of a 4-turn helix with an unfolded linker at its C-terminus.
- Family:
-
- Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB2 subfamily.
Function for KCNMB2 Gene
Molecular function for KCNMB2 Gene
- UniProtKB/Swiss-Prot Function:
- Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008200 | ion channel inhibitor activity | TAS | 10097176 |
| GO:0015269 | calcium-activated potassium channel activity | IEA,IDA | 10692449 |
| GO:0015459 | potassium channel regulator activity | TAS | 10097176 |
Phenotypes for KCNMB2 Gene
- MGI mutant phenotypes for KCNMB2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for KCNMB2:
Animal Models for KCNMB2 Gene
- MGI Knock Outs for KCNMB2:
-
- Kcnmb2 tm1.2Clin
Animal Model Products
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-
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-
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CRISPR Products
-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNMB2
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miRNA for KCNMB2 Gene
- miRTarBase miRNAs that target KCNMB2
miRNA Products
- Search ViGene Biosciences for KCNMB2
Inhibitory RNA Products
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-
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Clone Products
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Cell Line Products
-
Horizon Cell Lines for KCNMB2
-
ViGene Biosciences adenoviral particle packaged cDNA for KCNMB2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for KCNMB2 gene
-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KCNMB2 Gene
Localization for KCNMB2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KCNMB2 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IDA | 10692449 |
| GO:0008076 | voltage-gated potassium channel complex | IDA | 10692449 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for KCNMB2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Vascular smooth muscle contraction | ||
| 2 | Insulin secretion | ||
| 3 | Nitric oxide stimulates guanylate cyclase |
.01
|
|
| 4 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
| 5 | Transmission across Chemical Synapses |
.62
|
|
Pathways by source for KCNMB2 Gene
7 Reactome pathways for KCNMB2 Gene
3 KEGG pathways for KCNMB2 Gene
Interacting Proteins for KCNMB2 Gene
Selected Interacting proteins:
Q9Y691-KCMB2_HUMAN
ENSP00000351068
for KCNMB2 Gene via
IID
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001508 | action potential | IDA | 10692449 |
| GO:0005513 | detection of calcium ion | IDA | 10692449 |
| GO:0006810 | transport | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006813 | potassium ion transport | IDA,IEA | 10692449 |
No data available for SIGNOR curated interactions for KCNMB2 Gene
Drugs & Compounds for KCNMB2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Miconazole | Approved, Investigational, Vet_approved | Pharma | Antagonist, Pore Blocker, Target, inhibitor | 3706 | ||
| Procaine | Approved, Investigational, Vet_approved | Pharma | Channel blocker, Target, binder | 49 | ||
| 4-Aminopyridine | Approved | Pharma | Pore Blocker | potassium channel-blocking agent, Non-selective KV channel blocker | 69 | |
| (2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium | Experimental | Pharma | Target | 0 | ||
| calcium | Nutra | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| HMR 1556 |
|
223749-46-0 |
|
|
(5) Tocris Compounds for KCNMB2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 4-Aminopyridine | Non-selective KV channel blocker | 504-24-5 |
| E-4031 dihydrochloride | KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | 113559-13-0 |
| HMR 1556 | Potent and selective Iks channel blocker | 223749-46-0 |
| Linopirdine dihydrochloride | KV7 (KCNQ) channel blocker | 113168-57-3 |
| XE 991 dihydrochloride | Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents | 122955-13-9 |
Transcripts for KCNMB2 Gene
mRNA/cDNA for KCNMB2 Gene
- (4) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (30) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for KCNMB2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for KCNMB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for KCNMB2
- GenScript: Design CRISPR guide RNA sequences for KCNMB2
miRNA Products
- Search ViGene Biosciences for KCNMB2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for KCNMB2
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-
ViGene Biosciences ready-to-package AAV shRNAs for KCNMB2 gene
Clone Products
- Sino Biological Human cDNA Clone for KCNMB2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for KCNMB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
-
Ovary (Reproductive System)
- Ovarian Somatic Cells Ovigerous Cord
mRNA differential expression in normal tissues according to GTEx for KCNMB2 Gene
This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (x5.1) and Brain - Hippocampus (x4.6).
NURSA nuclear receptor signaling pathways regulating expression of KCNMB2 Gene:
KCNMB2SOURCE GeneReport for Unigene cluster for KCNMB2 Gene:
Hs.478368mRNA Expression by UniProt/SwissProt for KCNMB2 Gene:
Q9Y691-KCMB2_HUMAN
Tissue specificity:
Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues.
Primer Products
-
OriGene qPCR primer pairs for KCNMB2
-
OriGene qPCR primer pairs and template standards for KCNMB2
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNMB2 Gene
Orthologs for KCNMB2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | KCNMB3 35 |
|
OneToOne | |
| KCNMB2 34 |
|
||||
| chimpanzee (Pan troglodytes) |
Mammalia | KCNMB2 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KCNMB2 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | KCNMB2 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | KCNMB2 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Kcnmb2 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Kcnmb2 34 |
|
||
| chicken (Gallus gallus) |
Aves | KCNMB2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | KCNMB2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | kcnmb2 34 |
|
||
| Str.13335 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | LOC796753 34 |
|
||
| CR855338.1 35 |
|
ManyToMany | |||
| kcnmb2 35 |
|
ManyToMany |
- Species where no ortholog for KCNMB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KCNMB2 Gene
(3) SIMAP similar genes for KCNMB2 Gene using alignment to 12 proteins:
Variants for KCNMB2 Gene
| SNP ID | Clin | Chr 03 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000015562 | -- | 178,671,119(+) | AAACA(A/C)ACGTA | intron-variant | |
| rs1000020575 | -- | 178,742,058(+) | CCAAC(G/T)GTTAA | intron-variant | |
| rs1000024062 | -- | 178,823,722(+) | CTGGA(A/G)CACAA | intron-variant | |
| rs1000030388 | -- | 178,729,251(+) | TCAGG(A/C)AAAAT | intron-variant | |
| rs1000043375 | -- | 178,838,377(+) | CTGCT(C/T)TACTC | intron-variant |
Residual Variation Intolerance Score:
38.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.48;
10.51% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for KCNMB2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KCNMB2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNMB2 Gene
Disorders for KCNMB2 Gene
Relevant External Links for KCNMB2
No disorders were found for KCNMB2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KCNMB2 Gene
Publications for KCNMB2 Gene
- Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog. (PMID: 10097176) Wallner M. … Toro L. (Proc. Natl. Acad. Sci. U.S.A. 1999) 2 3 4 64
- Germline genomic variants associated with childhood acute lymphoblastic leukemia. (PMID: 19684603) Trevino L.R. … Relling M.V. (Nat. Genet. 2009) 3 46 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Inactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues. (PMID: 12566540) Xia X.-M. … Lingle C.J. (J. Gen. Physiol. 2003) 3 4 64
- New disguises for an old channel: MaxiK channel beta-subunits. (PMID: 12136044) Orio P. … Latorre R. (News Physiol. Sci. 2002) 3 4 64
Products for KCNMB2 Gene
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for KCNMB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
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- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer