KCNK9 Gene
protein-coding GIFtS: 60
GCID: GC08M140693
|
|
potassium channel, subfamily K, member 9
| |
Aliases
for KCNK9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Potassium Channel, Subfamily K, Member 91 2 | | Two Pore Potassium Channel KT3.22 3 | | TASK31 2 3 5 | | TWIK-Related Acid-Sensitive K(+) Channel 32 3 | | K2p9.11 2 | | KT3.22 | | TASK-31 2 | | Potassium Channel Subfamily K Member 92 | | Acid-Sensitive Potassium Channel Protein TASK-32 3 | | Potassium Channel TASK32 | | Two Pore K(+) Channel KT3.22 3 | | TWIK-Related Acid-Sensitive K+ Channel 32 |
Export aliases for KCNK9 gene to outside databasesPrevious GC identifers: GC08M139585 GC08M140782 GC08M140309 GC08M140595 GC08M135936 |
Summaries
for KCNK9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KCNK9:
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, andis highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in severaltypes of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferentialexpression from the maternal allele. (provided by RefSeq, Oct 2010)
UniProtKB/Swiss-Prot: KCNK9_HUMAN, Q9NPC2Function: pH-dependent, voltage-insensitive, background potassium channel protein
Gene Wiki entry for KCNK9
|
Genomic Views
for KCNK9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KCNK9 gene promoter:
NF-1 NF-1/L GCNF MyoD E47 CREB deltaCREB GCNF-1 COMP1 GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KCNK9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNK9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.3 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24.3KCNK9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M140693: view genomic region
(about GC identifiers)
Start:
|
140,613,081 bp from pter |
End:
|
140,715,299 bp from pter |
Size:
|
102,219 bases |
Orientation:
|
minus strand |
|
Proteins
for KCNK9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KCNK9_HUMAN, Q9NPC2 (See
protein sequence)Recommended Name: Potassium channel subfamily K member 9 Size: 374 amino acids; 42264 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Miscellaneous: Inhibited by phorbol 12-myristate 13-acetate (PMA). TASK-3 current is strongly decreased in the presenceof an extracellular pH inferior to 7.0
Miscellaneous: Overexpressed in a high proportion of breast cancers. May confer resistance to growth factor deprivationand hypoxia, thereby promoting tumor cell survival in poorly oxygenated areas of solid tumors
6/13 PDB 3D structures from  and Proteopedia  for KCNK9 (see all 13):3P1N (3D)
3P1O (3D)
3P1P (3D)
3P1Q (3D)
3P1R (3D)
3P1S (3D)
Secondary accessions: Q2M290 Q540F2Explore the universe of human proteins at neXtProt for KCNK9: NX_Q9NPC2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NPC2
KCNK9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057685.1
ENSEMBL proteins: ENSP00000429847 ENSP00000430676 ENSP00000302166 Reactome Protein details: Q9NPC2
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
KCNK9 for ontologies About GeneDecksing
KCNK9 Antibody Products:
Assay Products for KCNK9: |
Protein
Domains /
Families
for KCNK9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KCNK9 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NPC2ProtoNet protein and cluster: Q9NPC2 4 Blocks protein families: IPB003092 TASK K+ channel signature IPB003280 Two pore domain K+ channel signature IPB005407 TASK-3 K+ channel signature IPB013099 Ion transport 2
UniProtKB/Swiss-Prot: KCNK9_HUMAN, Q9NPC2Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family |
Function
for KCNK9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KCNK9_HUMAN, Q9NPC2Function: pH-dependent, voltage-insensitive, background potassium channel protein
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK9
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KCNK9 (NM_016601) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNK9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK9 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK9 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005244 | voltage-gated ion channel activity |
IEA | -- | | GO:0005267 | potassium channel activity |
NAS | -- | | GO:0042803 | protein homodimerization activity |
IEA | -- | | GO:0046982 | protein heterodimerization activity |
IEA | -- |
KCNK9 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for KCNK9:
Animal Models:
Mouse knock-outs for KCNK9: Kcnk9tm1Sgb Kcnk9tm1.1Fles Kcnk9tm1.1Daba
7 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Kcnk9):
KCNK9 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KCNK9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sweet Taste Signaling | | | 2 | Activation of cAMP-Dependent PKA | | | 3 | Neuropathic Pain-Signaling in Dorsal Horn Neurons | | | 4 | Hepatic ABC Transporters | | | 5 | Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KCNK9
5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KCNK9 (see all 13)
1  BioSystems Pathway for KCNK9
4 
Reactome Pathways for KCNK9
1  PharmGKB Pathway for KCNK9
KCNK9 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KCNK9
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for KCNK9 (Q9NPC23 ENSP000003021664) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
KCNK9 for ontologies About GeneDecksing
|
Drugs & Compounds
for KCNK9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KCNK9 for compounds About GeneDecksing
 Compounds for KCNK9 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| YS-035 hydrochloride | Inhibits K+ outward/pacemaker current | [33978-72-2] | | DMP 543 | K+ channel blocker and potent ACh release enhancer | [160588-45-4] |
2 DrugBank Compounds for KCNK9 About this table
6 Novoseek chemical compound relationships for KCNK9 gene About this table
Search CenterWatch for drugs/clinical trials and news about KCNK9
|
Transcripts
for KCNK9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KCNK9 gene: NM_016601.2 Unigene Cluster for KCNK9: Potassium channel, subfamily K, member 9 Hs.493037 [show with all ESTs]Unigene Representative Sequence: AK0907076 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000522317(uc003yve.1 uc003yvf.1) ENST00000523477 ENST00000523653
ENST00000519923 ENST00000520439(uc003yvg.1) ENST00000303015
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK9
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KCNK9 (NM_016601) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNK9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK9 |
Additional cDNA sequence: AF212829.1 AF248241.1 AF257080.1 AF279809.1 AK090707.1 AK095204.1 AY190605.1 BC034734.1 BC075079.2 BC075080.2 BC112063.1 BC112065.1 5 DOTS entries: DT.101970276 DT.99932762 DT.40122834 DT.410703 DT.40312590 24/44 AceView cDNA sequences (see all 44): AF257080 BX092753 AF279809 BC075080 AK090707 BC075079 BC034734 AF212829 BG575621 AY190605 F10471 AA676876 BF061574 NM_016601 F13494 AW085193 BE313755 AK095204 BI754880 CO247577 CO248626 CO245105 AK094401 CO248082
GeneLoc Exon Structure
|
Expression
for KCNK9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KCNK9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAGGCACTC
About this image
See KCNK9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KCNK9
SOURCE GeneReport for Unigene cluster: Hs.493037
UniProtKB/Swiss-Prot: KCNK9_HUMAN, Q9NPC2Tissue specificity: Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung
SABiosciences Custom PCR Arrays for KCNK9
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNK9
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KCNK9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNK9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNK9 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK9 |
Orthologs
for KCNK9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KCNK9 gene from 6/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC1008595451 |
potassium channel subfamily K member 9-like |
83.42(n)
90.91(a) |
|
100859545 XM_003640857.1 XP_003640905.1 |
lizard
(Anolis carolinensis) |
Reptilia |
KCNK96 |
-- |
85(a) |
1 ↔ 1 |
4(16041507-16127709) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.140392 |
Transcribed sequence with moderate similarity to protein more |
82.45(n) |
|
BX745213.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC7997041 |
novel protein similar to vertebrate potassium channel, more |
78.52(n)
81.28(a) |
|
799704 NM_001128549.1 NP_001122021.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG96373
Task71 |
inward rectifier potassium channel3
CG9361-PA1 |
57(a)
(best of 2)3
57.56(n)1
52.67(a)1 |
|
87F73
411251 NM_141634.21 NP_649891.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
twk-233 |
Expression: neurons, muscle |
55(a)
(best of 2) |
|
II(2684746-2686974) -- |
ENSEMBL Gene Tree for KCNK9 (if available)
TreeFam Gene Tree for KCNK9 (if available) |
Paralogs
for KCNK9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KCNK9 gene
- KCNK152 KCNK52 KCNK162 KCNK32 KCNK122 KCNK62 KCNK22 KCNK182
- KCNK172 KCNK102 KCNK72 KCNK42 KCNK132 KCNK12
3 SIMAP similar genes for KCNK9 using alignment to 1 protein entry: KCNK9_HUMAN:KCNK15 KCNK3 KCNK16
KCNK9 for paralogs About GeneDecksing
|
Genomic Variants
for KCNK9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KCNK9 (140613081 - 140715299 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for KCNK9
2 Indels: 47481 13136
Human Gene Mutation Database (HGMD): KCNK9
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for KCNK9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KCNK9 for disorders About GeneDecksing
OMIM gene information: 605874
OMIM disorders: 612292
UniProtKB/Swiss-Prot: KCNK9_HUMAN, Q9NPC2
Defects in KCNK9 are the cause of Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:612292]. Asyndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism
17  diseases for KCNK9: About MalaCardsbirk-barel syndrome childhood absence epilepsy absence epilepsy breast cancer
fetal alcohol spectrum disorder prosopagnosia hyperaldosteronism carcinoma
hypotonia aldosteronism medulloblastoma alcoholism
pharyngitis colorectal cancer hypoxia melanoma
neuronitis
3 diseases from the University of Copenhagen DISEASES database for KCNK9:Birk-Barel syndrome Juvenile absence epilepsy Central sleep apnea 3 Novoseek disease relationships for KCNK9 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| childhood absence epilepsy |
71.1 |
1 |
11857586 (1) |
| absence seizures |
52.6 |
5 |
15781965 (3), 11857586 (2) |
| acidosis |
31.7 |
1 |
11042359 (1) |
Human Genome Epidemiology (HuGE) Navigator: KCNK9 (2 documents)
Export disorders for KCNK9 gene to outside databases
|
Publications
for KCNK9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KCNK9 gene, integrated from 9 sources (see all 58):
(articles sorted by number of sources associating them with KCNK9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1. (PubMed id 11431495)1, 2, 9 Vega-Saenz de Miera E.... Rudy B. (2001)
- TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histidine as pH sensor. (PubMed id 10747866)1, 2, 9 Rajan S.... Derst C. (2000)
- Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel. (PubMed id 11042359)1, 2, 9 Chapman C.G.... Gloger I.S. (2000)
- Maternally inherited Birk Barel mental retardation dysmorphism syndrome caused by a mutation in the genomically imprinted potassium channel KCNK9. (PubMed id 18678320)1, 2 Barel O.... Birk O.S. (2008)
- International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. (PubMed id 16382106)1, 3 Goldstein S.A....Rajan S. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. (PubMed id 12676587)1, 2 Mu D.... Powers S. (2003)
- TASK-3, a new member of the tandem pore K(+) channel family. (PubMed id 10734076)1, 3 Kim Y....Kim D. (2000)
- Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. (PubMed id 12782791)1, 9 Pei L....Hoey T. (2003)
- Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc. (PubMed id 15284350)1, 9 Clarke C.E....Mathie A. (2004)
|
External Searches for KCNK9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KCNK9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KCNK9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KCNK9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KCNK9 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KCNK9 gene:
Search GeneIP for patents involving KCNK9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KCNK9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KCNK9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KCNK9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNK9 | | | OriGene Protein Over-expression Lysate for KCNK9 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KCNK9 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KCNK9 | | OriGene Custom Protein Services for KCNK9 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KCNK9 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNK9 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNK9 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNK9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNK9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNK9 |
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| | | | Tocris compounds for KCNK9 |
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 | | | KCNK9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK9 |
|  |  |  | | | | Search ThermoFisher Antibodies for KCNK9 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK9 |
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