Aliases for KCNK6 Gene
External Ids for KCNK6 Gene
Previous GeneCards Identifiers for KCNK6 Gene
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNK6 Gene
KCNK6 (Potassium Channel, Two Pore Domain Subfamily K, Member 6) is a Protein Coding gene. Diseases associated with KCNK6 include hemopericardium and developmental coordination disorder. Among its related pathways are Activation of cAMP-Dependent PKA and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK3.
UniProtKB/Swiss-Prot for KCNK6 Gene
Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions