Aliases for KCNK5 Gene
Aliases for KCNK5 Gene
- Potassium Two Pore Domain Channel Subfamily K Member 5 2 3 5
- Potassium Channel, Two Pore Domain Subfamily K, Member 5 2 3
- Acid-Sensitive Potassium Channel Protein TASK-2 3 4
- TWIK-Related Acid-Sensitive K(+) Channel 2 3 4
- TASK2 3 4
- Potassium Channel, Subfamily K, Member 1 (TASK-2) 3
- Potassium Channel, Subfamily, Member 5 (KCNK5) 3
- Potassium Channel, Subfamily K, Member 5 2
External Ids for KCNK5 Gene
- HGNC: 6280
- Entrez Gene: 8645
- Ensembl: ENSG00000164626
- OMIM: 603493
- UniProtKB: O95279
Previous GeneCards Identifiers for KCNK5 Gene
- GC06M039158
- GC06M039203
- GC06M039264
- GC06M038875
- GC06M039208
- GC06M039242
- GC06M039292
- GC06M039246
- GC06M039352
- GC06M039381
- GC06M039407
- GC06M039442
Summaries for KCNK5 Gene
-
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNK5 Gene
KCNK5 (Potassium Two Pore Domain Channel Subfamily K Member 5) is a Protein Coding gene. Diseases associated with KCNK5 include Balkan Nephropathy and Central Hypoventilation Syndrome, Congenital. Among its related pathways are Collagen chain trimerization and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK10.
UniProtKB/Swiss-Prot for KCNK5 Gene
-
pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KCNK5 Gene
Genomics for KCNK5 Gene
Regulatory Elements for KCNK5 Gene
Enhancers for KCNK5 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G039279 | 1.1 | FANTOM5 ENCODE | 13.9 | -50.9 | -50913 | 2.7 | ATF1 KLF17 RAD21 YY1 SCRT2 FOS CREM NCOA1 ZNF518A NR2F2 | KCNK17 KCNK5 PIR44224 |
| GH06G039251 | 1.2 | ENCODE dbSUPER | 10.4 | -22.0 | -21972 | 0.3 | PKNOX1 SIN3A FEZF1 ZNF2 YY1 TCF12 FOS KLF7 ZNF263 YY2 | KCNK5 PIR44224 |
| GH06G039101 | 1.2 | Ensembl ENCODE dbSUPER | 10.4 | +127.4 | 127352 | 1.1 | CTCF PKNOX1 ATF1 RB1 ZFP64 HLF REST RAD21 JUND KLF16 | SAYSD1 GLP1R KCNK17 KCNK5 PIR34726 GC06M039484 LOC105375046 |
| GH06G039323 | 1 | dbSUPER | 10.1 | -98.0 | -98017 | 7.7 | FOXA2 YY1 FOS ZNF548 ZNF263 MCM3 SP5 NFIL3 MIER3 SMARCA4 | KCNK5 SAYSD1 KCNK17 KCNK16 LOC100124373 |
| GH06G039217 | 1.5 | Ensembl ENCODE dbSUPER | 5.9 | +10.8 | 10779 | 3.1 | HDGF ATF1 PKNOX1 ARNT SIN3A FEZF1 TCF12 GLIS2 ZNF766 GATA2 | KCNK5 PIR34969 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around KCNK5 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the KCNK5 gene promoter:
Regulatory Element Products
Genomic Location for KCNK5 Gene
- Chromosome:
- 6
- Start:
- 39,188,971 bp from pter
- End:
- 39,229,475 bp from pter
- Size:
- 40,505 bases
- Orientation:
- Minus strand
Genomic View for KCNK5 Gene
Genes around KCNK5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.2 by Ensembl
- 6p21.2 by Entrez Gene
- 6p21.2 by HGNC
KCNK5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KCNK5 Gene
Proteins for KCNK5 Gene
-
Protein details for KCNK5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95279-KCNK5_HUMAN
- Recommended name:
- Potassium channel subfamily K member 5
- Protein Accession:
- O95279
- B2RAQ6
- B5TJL2
- Q5VV76
Protein attributes for KCNK5 Gene
- Size:
- 499 amino acids
- Molecular mass:
- 55130 Da
- Quaternary structure:
-
- Homodimer; disulfide-linked.
- Miscellaneous:
-
- Inhibited by quinine, quinidine and external acidification.
Post-translational modifications for KCNK5 Gene
Other Protein References for KCNK5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for KCNK5
- Novus Biologicals Antibodies for KCNK5
-
Abcam antibodies for KCNK5
- Invitrogen Antibodies for KCNK5
- antibodies-online Antibodies for KCNK5: See all 18
- GeneTex KCNK5 antibody for KCNK5
-
Santa Cruz Biotechnology (SCBT) Antibodies for KCNK5
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-
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Assay Products
No data available for DME Specific Peptides for KCNK5 Gene
Domains & Families for KCNK5 Gene
Gene Families for KCNK5 Gene
Protein Domains for KCNK5 Gene
Suggested Antigen Peptide Sequences for KCNK5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O95279UniProtKB/Swiss-Prot:
KCNK5_HUMAN :- Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
- Domain:
-
- Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Function for KCNK5 Gene
Molecular function for KCNK5 Gene
- GENATLAS Biochemistry:
- potassium non voltage-gated channel inwardly rectifying,subfamily K,member 5,mainly expressed in cortical tubules and collecting ducts of kidneys
- UniProtKB/Swiss-Prot Function:
- pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005249 | voltage-gated potassium channel activity | IEA | -- |
| GO:0005267 | potassium channel activity | TAS | 9812978 |
Phenotypes for KCNK5 Gene
- MGI mutant phenotypes for KCNK5:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for KCNK5:
Animal Model Products
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miRNA for KCNK5 Gene
- miRTarBase miRNAs that target KCNK5
-
- hsa-mir-335-5p (MIRT017258)
- hsa-mir-602 (MIRT610745)
- hsa-mir-8485 (MIRT610746)
- hsa-mir-4680-5p (MIRT614942)
- hsa-mir-1-5p (MIRT614943)
- hsa-mir-5003-3p (MIRT614944)
- hsa-mir-487a-3p (MIRT616587)
- hsa-mir-154-3p (MIRT616588)
- hsa-mir-362-3p (MIRT623502)
- hsa-mir-329-3p (MIRT623503)
- hsa-mir-5590-5p (MIRT623504)
- hsa-mir-513a-5p (MIRT623505)
- hsa-mir-6817-5p (MIRT623506)
- hsa-mir-4769-3p (MIRT623507)
- hsa-mir-34b-3p (MIRT623508)
- hsa-mir-552-5p (MIRT657012)
- hsa-mir-3913-5p (MIRT657013)
- hsa-mir-3122 (MIRT657014)
- hsa-mir-4298 (MIRT657015)
- hsa-mir-1302 (MIRT657016)
- hsa-mir-302d-5p (MIRT657017)
- hsa-mir-302b-5p (MIRT657018)
- hsa-mir-150-5p (MIRT657019)
- hsa-mir-3189-3p (MIRT657020)
- hsa-mir-212-5p (MIRT657021)
- hsa-mir-500b-5p (MIRT657022)
- hsa-mir-362-5p (MIRT657023)
- hsa-mir-7161-3p (MIRT657024)
- hsa-mir-28-3p (MIRT657025)
- hsa-mir-6776-3p (MIRT657026)
- hsa-mir-7977 (MIRT670393)
- hsa-mir-24-3p (MIRT670394)
- hsa-mir-4284 (MIRT670395)
- hsa-mir-564 (MIRT670396)
- hsa-mir-383-3p (MIRT670397)
- hsa-mir-372-5p (MIRT713800)
- hsa-mir-371a-5p (MIRT713801)
- hsa-mir-616-5p (MIRT713802)
- hsa-mir-373-5p (MIRT713803)
- hsa-mir-371b-5p (MIRT713804)
- hsa-mir-3065-5p (MIRT713805)
- hsa-mir-3613-3p (MIRT713806)
- hsa-mir-3529-3p (MIRT713807)
- hsa-mir-6809-3p (MIRT722768)
- hsa-mir-6833-3p (MIRT722769)
- hsa-mir-4768-5p (MIRT722770)
- hsa-mir-29b-2-5p (MIRT722771)
- hsa-mir-4753-3p (MIRT722772)
- hsa-mir-29b-1-5p (MIRT722773)
- hsa-mir-1236-3p (MIRT722774)
- hsa-mir-6515-3p (MIRT722775)
- hsa-mir-4793-5p (MIRT722776)
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Horizon Cell Lines for KCNK5
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KCNK5 Gene
Localization for KCNK5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KCNK5 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 2 |
| endoplasmic reticulum | 2 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005887 | integral component of plasma membrane | TAS | 9812978 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for KCNK5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Sweet Taste Signaling |
.37
|
|
| 2 | Activation of cAMP-Dependent PKA |
.77
|
.56
|
| 3 | Neuropathic Pain-Signaling in Dorsal Horn Neurons | ||
| 4 | Cardiac conduction | ||
| 5 | Hepatic ABC Transporters | ||
Pathways by source for KCNK5 Gene
3 Reactome pathways for KCNK5 Gene
2 KEGG pathways for KCNK5 Gene
13 Qiagen pathways for KCNK5 Gene
Interacting Proteins for KCNK5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006813 | potassium ion transport | TAS | 9812978 |
| GO:0007588 | excretion | TAS | 9812978 |
| GO:0034765 | regulation of ion transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for KCNK5 Gene
Drugs & Compounds for KCNK5 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Doxapram HCl | Pharma | 0 | ||||
| BL 1249 | Pharma | Putative activator of potassium TREK-1, Putative K2P2.1 (TREK-1) channel opener | 0 | |||
| DMP 543 | Pharma | K+ channel blocker and potent ACh release enhancer | 0 | |||
| ML365 | Pharma | Potent and selective TASK-1 channel blocker | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| PK-THPP |
|
1332454-07-5 |
|
|
||
| Spadin |
|
1270083-24-3 |
|
|
(5) Tocris Compounds for KCNK5 Gene
| Compound | Action | Cas Number |
|---|---|---|
| BL 1249 | Putative K2P2.1 (TREK-1) channel opener | 18200-13-0 |
| DMP 543 | K+ channel blocker and potent ACh release enhancer | 160588-45-4 |
| ML 365 | Potent and selective TASK-1 channel blocker | 947914-18-3 |
| PK-THPP | Potent TASK-3 channel blocker | 1332454-07-5 |
| Spadin | Potent TREK-1 channel blocker | 1270083-24-3 |
(1) ApexBio Compounds for KCNK5 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Doxapram HCl | 7081-53-0 |
Drug Products
- ApexBio compounds for KCNK5
Transcripts for KCNK5 Gene
mRNA/cDNA for KCNK5 Gene
- (3) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (75) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for KCNK5 Gene
CRISPR Products
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Expression for KCNK5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Periportal Hepatocytes Liver Lobule
-
Blood (Hematopoietic System)
- Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone Marrow
-
Kidney (Urinary System)
mRNA differential expression in normal tissues according to GTEx for KCNK5 Gene
This gene is overexpressed in Kidney - Cortex (x9.8) and Skin - Sun Exposed (Lower leg) (x5.1).
NURSA nuclear receptor signaling pathways regulating expression of KCNK5 Gene:
KCNK5SOURCE GeneReport for Unigene cluster for KCNK5 Gene:
Hs.444448mRNA Expression by UniProt/SwissProt for KCNK5 Gene:
O95279-KCNK5_HUMAN
Tissue specificity:
Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
Evidence on tissue expression from TISSUES for KCNK5 Gene
- Kidney(4.4)
- Nervous system(4.4)
Primer Products
-
OriGene qPCR primer pairs for KCNK5
-
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No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNK5 Gene
Orthologs for KCNK5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | KCNK5 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | KCNK5 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | KCNK5 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Kcnk5 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Kcnk5 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KCNK5 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | KCNK5 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | KCNK5 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | KCNK5 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | kcnk5 34 |
|
||
| Str.16771 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.7279 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | kcnk5a 34 35 |
|
||
| kcnk5b 35 |
|
OneToMany | |||
| Dr.17953 34 |
|
||||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.6929 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.1682 34 |
|
- Species where no ortholog for KCNK5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KCNK5 Gene
Variants for KCNK5 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000010562 | -- | 39,221,312(+) | CCCAA(A/G)CCTGT | intron-variant | |
| rs1000030532 | -- | 39,194,878(+) | CAGTA(C/G)TTAAG | intron-variant, upstream-variant-2KB | |
| rs1000079352 | -- | 39,215,941(+) | CAACC(A/C)CACCT | intron-variant | |
| rs1000189534 | -- | 39,193,952(+) | AAAAA(G/T)GCCAT | intron-variant | |
| rs1000281101 | -- | 39,200,863(+) | TGGGG(-/C)ATCCC | intron-variant |
Residual Variation Intolerance Score:
66.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.00;
60.22% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for KCNK5 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNK5 Gene
Disorders for KCNK5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| balkan nephropathy |
|
|
| central hypoventilation syndrome, congenital |
|
|
Search KCNK5 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for KCNK5
No data available for UniProtKB/Swiss-Prot and Genatlas for KCNK5 Gene
Publications for KCNK5 Gene
- Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney. (PMID: 9812978) Reyes R. … Lazdunski M. (J. Biol. Chem. 1998) 2 3 4 22 64
- Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein. (PMID: 18516069) Gierten J. … Thomas D. (Br. J. Pharmacol. 2008) 3 4 64
- International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. (PMID: 16382106) Goldstein S.A. … Rajan S. (Pharmacol. Rev. 2005) 2 3 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellum. (PMID: 15197476) RusznA!k Z. … SzA1cs G. (Cell. Mol. Life Sci. 2004) 3 22 64
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- Santa Cruz Biotechnology (SCBT) Antibodies for KCNK5
- Search Santa Cruz Biotechnology (SCBT) for KCNK5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KCNK5
- Horizon Cell Lines for KCNK5
- Cyagen custom Knockout/knockin (KOKI) mouse models for KCNK5
- VectorBuilder custom plasmid, inducible vectors for KCNK5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KCNK5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for KCNK5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer