KCNK18 Gene
protein-coding GIFtS: 53
GCID: GC10P118947
|
|
potassium channel, subfamily K, member 18
| |
Aliases
for KCNK18 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Potassium Channel, Subfamily K, Member 181 2 | | TWIK-Related Individual Potassium Channel2 3 | | TRESK1 2 3 5 | | TWIK-Related Spinal Cord Potassium Channel2 3 | | TRIK1 2 3 5 | | MGR132 5 | | K2p18.11 2 | | Potassium Channel Subfamily K Member 182 | | TRESK-21 2 | | TWIK-Related Individual K+ Channel2 | | TRESK21 2 | | TWIK-Related Spinal Cord K+ Channel2 |
Export aliases for KCNK18 gene to outside databasesPrevious GC identifer: GC10P112584 |
Summaries
for KCNK18 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KCNK18:
Potassium channels play a role in many cellular processes including maintenance of the action potential, musclecontraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily ofpotassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outwardrectifying potassium channel. A mutation in this gene has been found to be associated with migraine withaura.(provided by RefSeq, Jan 2011)
UniProtKB/Swiss-Prot: KCNKI_HUMAN, Q7Z418Function: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Mayfunction as background potassium channel that sets the resting membrane potential. Channel activity is directlyactivated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustlyactivates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the currentto the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturatedfree fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be theprimary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensoryfunction with special respect to pain sensation (By similarity)
Gene Wiki entry for KCNK18
|
Genomic Views
for KCNK18 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KCNK18 gene promoter:
AP-2rep AP-1 p300 HTF NRSF form 1 NRSF form 2 HNF-1A AREB6 HNF-1 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for KCNK18
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNK18 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q25.3 Ensembl cytogenetic band: 10q25.3 HGNC cytogenetic band: 10q26.11KCNK18 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P118947: view genomic region
(about GC identifiers)
Start:
|
118,957,000 bp from pter |
End:
|
118,969,810 bp from pter |
Size:
|
12,811 bases |
Orientation:
|
plus strand |
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Proteins
for KCNK18 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KCNKI_HUMAN, Q7Z418 (See
protein sequence)Recommended Name: Potassium channel subfamily K member 18 Size: 384 amino acids; 43671 Da
Subunit: Interacts with calcineurin (By similarity). Interacts with YWHAH, in a phosphorylation-dependent manner (Bysimilarity)
Subcellular location: Cell membrane; Multi-pass membrane protein
Miscellaneous: In contrast to its mouse ortholog, it is not regulated by extracellular protons
Secondary accessions: Q5SQQ8Explore the universe of human proteins at neXtProt for KCNK18: NX_Q7Z418
Post-translational modifications:
Phosphorylation of Ser-252 is required for the binding of 14-3-3eta/YWHAH. Calcineurin-mediated dephosphorylation ofSer-264 enhances channel activity (By similarity)1
N-glycosylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z418
KCNK18 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_862823.1
ENSEMBL proteins: ENSP00000334650 Reactome Protein details: Q7Z418
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
KCNK18 for ontologies About GeneDecksing
KCNK18 Antibody Products:
Assay Products for KCNK18: |
Protein
Domains /
Families
for KCNK18 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KCNK18 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7Z418ProtoNet protein and cluster: Q7Z418 2 Blocks protein families: IPB003280 Two pore domain K+ channel signature IPB013099 Ion transport 2
UniProtKB/Swiss-Prot: KCNKI_HUMAN, Q7Z418Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family |
Function
for KCNK18 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KCNKI_HUMAN, Q7Z418Function: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Mayfunction as background potassium channel that sets the resting membrane potential. Channel activity is directlyactivated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustlyactivates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the currentto the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturatedfree fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be theprimary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensoryfunction with special respect to pain sensation (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK18 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK18 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
KCNK18 for ontologies About GeneDecksing
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Kcnk18):
KCNK18 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KCNK18 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Potassium Channels | | | 2 | Tandem pore domain potassium channels | | | 3 | TWIK-related spinal cord K+ channel (TRESK) | | | 4 | Potassium transporters: inward current | | | 5 | Transmission across Chemical Synapses | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KCNK18
4 
Reactome Pathways for KCNK18
KCNK18 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCNK18
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for KCNK18 (Q7Z4183 ENSP000003346504) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
KCNK18 for ontologies About GeneDecksing
|
Drugs & Compounds
for KCNK18 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KCNK18 for compounds About GeneDecksing
 Compounds for KCNK18 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| YS-035 hydrochloride | Inhibits K+ outward/pacemaker current | [33978-72-2] | | DMP 543 | K+ channel blocker and potent ACh release enhancer | [160588-45-4] |
3 Novoseek chemical compound relationships for KCNK18 gene About this table
Search CenterWatch for drugs/clinical trials and news about KCNK18 / KCNKI
|
Transcripts
for KCNK18 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KCNK18 gene: NM_181840.1 Unigene Cluster for KCNK18: Potassium channel, subfamily K, member 18 Hs.449650 Unigene Representative Sequence: AB0871381 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000334549(uc010qsr.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK18 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KCNK18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KCNK18 (NM_181840) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KCNK18 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK18 |
Additional cDNA sequence: AB087138.1 1 DOTS entry: DT.100697388 2 AceView cDNA sequences: AB087138 NM_181840
GeneLoc Exon Structure
|
Expression
for KCNK18 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KCNK18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAGGAGTA
About this image
See KCNK18 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.449650
UniProtKB/Swiss-Prot: KCNKI_HUMAN, Q7Z418Tissue specificity: Expressed specifically in dorsal root ganglion and trigeminal ganglion neurons. Detected at lowlevels in spinal cord
SABiosciences Custom PCR Arrays for KCNK18
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KCNK18
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KCNK18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNK18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNK18 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK18 |
Orthologs
for KCNK18 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KCNK18 gene from 5/16 species (see all 16) About this table
ENSEMBL Gene Tree for KCNK18 (if available)
TreeFam Gene Tree for KCNK18 (if available) |
Paralogs
for KCNK18 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KCNK18 gene
- KCNK152 KCNK52 KCNK162 KCNK32 KCNK122 KCNK92 KCNK62 KCNK22
- KCNK172 KCNK102 KCNK72 KCNK42 KCNK132 KCNK12
KCNK18 for paralogs About GeneDecksing
|
Genomic Variants
for KCNK18 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KCNK18 (118957000 - 118969810 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KCNK18
1 CNV: 48031
Human Gene Mutation Database (HGMD): KCNK18
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNK18 |
|
Disorders
/ Diseases
for KCNK18 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KCNK18 for disorders About GeneDecksing
OMIM gene information: 613655
OMIM disorders: 613656
UniProtKB/Swiss-Prot: KCNKI_HUMAN, Q7Z418
Defects in KCNK18 are a cause of migraine with or without aura type 13 (MGR13) [MIM:613656]. A form ofmigraine trasmitted in an autosomal dominant pattern. Migraine is a disabling symptom complex of periodic headaches,usually temporal and unilateral. Headaches are often accompanied by irritability, nausea, vomiting and photobia,preceded by constriction of the cranial arteries. The two major subtypes are common migraine (migraine without aura)and classic migraine (migraine with aura). Classic migraine is characterized by recurrent attacks of reversibleneurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensorydisturbances, such as blurred vision, hallucinations, vertigo, numbness and difficulty in concentrating and speaking.Note=Susceptibility to migraine has been shown to be conferred by a frameshift mutation that segregates with thedisorder in a large multigenerational family. Migraine was associated with sensitivity to lights, sounds, and smells,as well as nausea and occasional vomiting. Triggers included fatigue, alcohol and bright lights. Mutations in KCNK18are a rare cause of migraine
7  diseases for KCNK18: About MalaCardsmigraine with aura migraine without aura migraine headache
paralysis alzheimer's disease neuronitis
1 disease from the University of Copenhagen DISEASES database for KCNK18:Migraine Human Genome Epidemiology (HuGE) Navigator: KCNK18 (2 documents)
Export disorders for KCNK18 gene to outside databases
|
Publications
for KCNK18 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KCNK18 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with KCNK18) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord. (PubMed id 12754259)1, 2, 9 Sano Y.... Furuichi K. (2003)
- A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura. (PubMed id 20871611)1, 2 Lafreniere R.G.... Rouleau G.A. (2010)
- N-linked glycosylation determines cell surface expres sion of two-pore-domain K+ channel TRESK. (PubMed id 20006580)1, 2 Egenberger B....DAPring F. (2010)
- International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. (PubMed id 16382106)1, 3 Goldstein S.A....Rajan S. (2005)
- TRESK background K(+) channel is inhibited by phospho rylation via two distinct pathways. (PubMed id 20215114)1, 9 CzirjA!k G. and Enyedi P. (2010)
- The two-pore domain K+ channel, TRESK, is activated by the cytoplasmic calcium signal through calcineurin. (PubMed id 14981085)1, 9 Czirjak G....Enyedi P. (2004)
- TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones. (PubMed id 17962323)2, 9 Dobler T....Doring F. (2007)
- TRESK: the lone ranger of two-pore domain potassium ch annels. (PubMed id 22115960)1 Enyedi P....Czirjak G. (2012)
- Migraine: Role of the TRESK two-pore potassium channe l. (PubMed id 21855646)1 LafreniA"re R.G. and Rouleau G.A. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
|
External Searches for KCNK18 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KCNK18 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KCNK18 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KCNK18 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KCNK18 | Pharmacogenomics, SNPs, Pathways | | Protein Spotlight | http://web.expasy.org/spotlight/back_issues/sptlt124.shtml |
|
| | |
About This Section
| Patent Information for KCNK18 gene:
Search GeneIP for patents involving KCNK18
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KCNK18 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KCNK18 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KCNK18 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNK18 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KCNK18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KCNK18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KCNK18 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK18 |
|  |  |  | | | | ThermoFisher Antibodies for KCNK18 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KCNK18 |
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