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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KCNK16 Gene

protein-coding   GIFtS: 53
GCID: GC06M039282

Potassium Channel, Subfamily K, Member 16

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Potassium Channel, Subfamily K, Member 161 2     TWIK-Related Alkaline PH-Activated K(+) Channel 12 3
TALK12 3 5     K2p16.12
2P Domain Potassium Channel Talk-12 3     Pancreatic Potassium Channel Talk-12
TALK-12 3     Potassium Channel Subfamily K Member 162

External Ids:    HGNC: 144641   Entrez Gene: 837952   Ensembl: ENSG000000959817   OMIM: 6073695   UniProtKB: Q96T553   

Export aliases for KCNK16 gene to outside databases

Previous GC identifers: GC06M039284 GC06M039329 GC06M039390 GC06M039000


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KCNK16 Gene:
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P
domains. This channel is an open rectifier which primarily passes outward current under physiological K+
concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several
alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
(provided by RefSeq, Sep 2008)

GeneCards Summary for KCNK16 Gene: 
KCNK16 (potassium channel, subfamily K, member 16) is a protein-coding gene. Diseases associated with KCNK16 include maturity-onset diabetes of the young, and pancreatitis, and among its related super-pathways are Melatonin Signaling and Activation of cAMP-Dependent PKA. GO annotations related to this gene include voltage-gated ion channel activity and potassium channel activity. An important paralog of this gene is KCNK15.

UniProtKB/Swiss-Prot: KCNKG_HUMAN, Q96T55
Function: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier
K(+) currents

Gene Wiki entry for KCNK16 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KCNK16 gene promoter:
         Oct-B1   RFX1   oct-B2   Pbx1a   Pax-2   Pax-2a   Tal-1beta   E47   Nkx6-1   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKCNK16 promoter sequence
   Search SABiosciences Chromatin IP Primers for KCNK16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KCNK16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2-p21.1   Ensembl cytogenetic band:  6p21.2   HGNC cytogenetic band: 6p21.2-p21.1

KCNK16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KCNK16 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M039282:  view genomic region     (about GC identifiers)

Start:
39,282,474 bp from pter      End:
39,290,744 bp from pter
Size:
8,271 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KCNKG_HUMAN, Q96T55 (See protein sequence)
Recommended Name: Potassium channel subfamily K member 16  
Size: 309 amino acids; 34153 Da
Subunit: Homodimer (Potential)
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Inhibited by Ba(2+), quinine, quinidine, chloroform and halothane. Activated at alkaline pH
Secondary accessions: B5TJL9 Q2M2N9 Q5TCF3 Q6X6Z3 Q6X6Z4 Q6X6Z5 Q9H591
Alternative splicing: 4 isoforms:  Q96T55-1   Q96T55-3   Q96T55-4   Q96T55-5   

Explore the universe of human proteins at neXtProt for KCNK16: NX_Q96T55

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96T55

  • KCNK16 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins (4 alternative transcripts): 
    NP_001128577.1  NP_001128578.1  NP_001128579.1  NP_115491.1  

    ENSEMBL proteins: 
     ENSP00000362326   ENSP00000391498   ENSP00000423842   ENSP00000362324   ENSP00000415375  
    Reactome Protein details: Q96T55
    Human Recombinant Protein Products for KCNK16: 
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    Cloud-Clone Corp. Proteins for KCNK16 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    KCNK16 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    KCN: Potassium channels
    KCNK: Voltage-gated ion channels / Potassium channels, Two-P

    IUPHAR Guide to PHARMACOLOGY protein family classification: K2P16.1 
    Two-P potassium channels

    3 InterPro protein domains:
     IPR003280 2pore_dom_K_chnl
     IPR003092 2pore_dom_K_chnl_TASK
     IPR013099 Ion_trans_2

    Graphical View of Domain Structure for InterPro Entry Q96T55

    ProtoNet protein and cluster: Q96T55

    3 Blocks protein domains:
    IPB003092 TASK K+ channel signature
    IPB003280 Two pore domain K+ channel signature
    IPB013099 Ion transport 2


    UniProtKB/Swiss-Prot: KCNKG_HUMAN, Q96T55
    Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family


    KCNK16 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCNKG_HUMAN, Q96T55
    Function: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier
    K(+) currents

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005216ion channel activity ----
    GO:0005244voltage-gated ion channel activity IEA--
    GO:0005267potassium channel activity IDA11263999
         
    KCNK16 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for KCNK16:
     Decreased cell number and incr 

         1 MGI phenotypic allele for Kcnk16 (no phenotypes)

    KCNK16 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Kcnk16tm1Lex for KCNK16

       inGenious Targeting Laboratory - Custom generated mouse model solutions for KCNK16 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KCNK16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KCNK16 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate KCNK16:
    hsa-miR-30b*
    SwitchGear 3'UTR luciferase reporter plasmidKCNK16 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KCNK16 About   (see all 8)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Bitter Taste Signaling0.44
    Melatonin Signaling0.72
    Sperm Motility0.37
    Cellular Effects of Sildenafil0.46
    2Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77
    3Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47
    Cholera Infection0.40
    Aldosterone Signaling in Epithelial Cells0.47
    4Hepatic ABC Transporters
    Hepatic ABC Transporters0.41
    MODY (Maturity-Onset Diabetes of Young)0.41
    5Transmission across Chemical Synapses
    Neuronal System0.67

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for KCNK16 (see all 13)
        Cholera Infection
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Hepatic ABC Transporters
    PKA Signaling
    Sweet Taste Signaling

    4        Reactome Pathways for KCNK16
        Potassium Channels
    TWIK-related alkaline pH activated K+ channel (TALK)
    Neuronal System
    Tandem pore domain potassium channels



    KCNK16 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KCNK16

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport ----
    GO:0006813potassium ion transport IDA11263999
    GO:0007268synaptic transmission TAS--
    GO:0055085transmembrane transport ----

    KCNK16 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for KCNK16 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Cesium chloridePotassium channel blocker; neuroprotective[7647-17-8]
    YS-035 hydrochlorideInhibits K+ outward/pacemaker current[33978-72-2]
    BL 1249Putative K2P2.1 (TREK-1) channel opener[18200-13-0]
    DMP 543K+ channel blocker and potent ACh release enhancer[160588-45-4]
    Tetraethylammonium chlorideNon-selective K+ channel blocker[56-34-8]

    Search CenterWatch for drugs/clinical trials and news about KCNK16 / KCNKG

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KCNK16 gene (4 alternative transcripts): 
    NM_001135105.1  NM_001135106.1  NM_001135107.1  NM_032115.3  

    Unigene Cluster for KCNK16:

    Potassium channel, subfamily K, member 16
    Hs.287765  [show with all ESTs]
    Unigene Representative Sequence: NM_001135105
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373229(uc003ooq.3 uc010jwy.3) ENST00000425054(uc003oor.4)
    ENST00000507712 ENST00000373227 ENST00000437525(uc011dtz.1)
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate KCNK16:
    hsa-miR-30b*
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    Inhib. RNA
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    Additional mRNA sequence: 

    AF358909.1 AY253145.1 AY253146.1 AY253147.1 BC111860.1 EU978943.1 

    3 DOTS entries:

    DT.101973012  DT.97774207  DT.97794751 

    22 AceView cDNA sequences:

    NM_032115 BQ925824 CK905734 BM504060 BQ128142 BU789531 BU789594 BU789868 
    AY253146 BU787720 AF358909 AY253147 AY253145 BQ127873 BI710990 BI711434 
    BQ268142 BQ777253 CK905735 CA843225 BQ787952 BQ952392 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for KCNK16    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d
    SP1:        -                             -     -     -                     
    SP2:                                            -     -                     
    SP3:                                      -     -                           
    SP4:                                      -     -     -                     
    SP5:                                                                        


    ECgene alternative splicing isoforms for KCNK16

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KCNK16 expression in normal human tissues (normalized intensities)      KCNK16 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACAAGTGGC
    KCNK16 Expression
    About this image


    KCNK16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 4 entries
             Endocrine Progenitor Cells Ventral Pancreatic Bud

    Genevestigator expression for KCNK16

    SOURCE GeneReport for Unigene cluster: Hs.287765

    UniProtKB/Swiss-Prot: KCNKG_HUMAN, Q96T55
    Tissue specificity: Highly expressed in pancreas. Not detectable in the other tissues tested

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KCNK16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for KCNK16 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kcnk161 , 5 potassium channel, subfamily K, member 161, 5 86.3(n)1
    88.01(a)1
      14 (11.49 cM)5
    745711  NM_029006.11  NP_083282.11 
     202627565 
    chicken
    (Gallus gallus)
    Aves KCNK161 potassium channel, subfamily K, member 16 68.96(n)
    64.86(a)
      772022  XM_001235223.1  XP_001235224.1 
    lizard
    (Anolis carolinensis)
    Reptilia KCNK166
    --
    --
    55(a)
    42(a)
    1 ↔ 1
    possible ortholog
    1(246677431-246691184)
    GL343261.1(1886624-1896458)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480255682   -- 73.59(n)    48025568 


    ENSEMBL Gene Tree for KCNK16 (if available)
    TreeFam Gene Tree for KCNK16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KCNK16 gene
    KCNK152  KCNK52  KCNK32  KCNK122  KCNK92  KCNK62  KCNK22  KCNK102  
    KCNK72  KCNK172  KCNK42  KCNK132  KCNK12  
    8 SIMAP similar genes for KCNK16 using alignment to 2 protein entries:     KCNKG_HUMAN (see all proteins):
    KCNK2    KCNK17    KCNK10    KCNK4    KCNK1    KCNK9
    KCNK6    KCNK15

    KCNK16 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KCNK16
    PGOHUM00000250175


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/255 SNPs in KCNK16 are shown (see all 255)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0636374
    ----see VAR_0636372 A G mis40--------
    VAR_0524304
    ----see VAR_0524302 P H mis40--------
    rs92962931,2
    C,F--39284283(+) TCCATA/CGGGAC 4 -- int11Minor allele frequency- C:0.07WA 118
    rs94625261,2
    F,A--39284341(+) GCAGTT/GGAGGT 4 -- int11Minor allele frequency- G:0.07WA 118
    rs94710671,2
    C,F,A--39284357(+) TCTGCA/GGGGTG 4 -- int11Minor allele frequency- G:0.07WA 118
    rs1132137791,2
    C,F--39284378(+) CTAGAC/TCAGAA 4 -- int11Minor allele frequency- T:0.03NA 120
    rs1896842221,2
    --39284438(+) TTTGGC/TTCCCT 4 -- int10--------
    rs1809023941,2
    C--39284554(+) TGTTCC/TCACCA 4 -- int10--------
    rs94625271,2,4
    C,F,A--39284574(+) TCCCCA/GAAGCC 8 F syn14Minor allele frequency- G:0.02NS WA NA EU 6055
    rs412731321,2
    C,F--39284597(+) AGTGAT/GGAAAG 8 /I /L mis13Minor allele frequency- G:0.00NA EU 5857

    HapMap Linkage Disequilibrium report for KCNK16 (39282474 - 39290744 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KCNK16:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv830645CNV Loss17160897
    nsv830644CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607369    OMIM disorders: --

    5 diseases for KCNK16:    About MalaCards
    maturity-onset diabetes of the young    pancreatitis    cholera    hepatitis
    neuronitis


    KCNK16 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KCNK16

    Export disorders for KCNK16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KCNK16 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KCNK16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels. (PubMed id 11263999)1, 2, 3 Girard C.... Lesage F. (2001)
    2. Functional properties of four splice variants of a human pancreatic tandem-pore K+ channel, TALK-1. (PubMed id 12724142)1, 2, 9 Han J.... Kim D. (2003)
    3. Meta-analysis of genome-wide association studies ident ifies eight new loci for type 2 diabetes in east Asians. (PubMed id 22158537)1, 4 Cho Y.S....Seielstad M. (2012)
    4. Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein. (PubMed id 18516069)1, 2 Gierten J....Thomas D. (2008)
    5. International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. (PubMed id 16382106)1, 3 Goldstein S.A....Rajan S. (2005)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Potassium leak channels and the KCNK family of two-P-domain subunits. (PubMed id 11256078)1 Goldstein S.A....Zilberberg N. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83795 HGNC: 14464 AceView: KCNK16 Ensembl:ENSG00000095981 euGenes: HUgn83795
    ECgene: KCNK16 H-InvDB: KCNK16

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KCNK16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KCNK16 gene:
    Search GeneIP for patents involving KCNK16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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