Aliases for KCNK13 Gene
External Ids for KCNK13 Gene
Previous GeneCards Identifiers for KCNK13 Gene
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013]
GeneCards Summary for KCNK13 Gene
KCNK13 (Potassium Channel, Two Pore Domain Subfamily K, Member 13) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK3.
UniProtKB/Swiss-Prot for KCNK13 Gene
Potassium channel displaying weak inward rectification in symmetrical K(+) solution.